CYP2C9 c.482-334C>T

Variant ID: 10-96707202-C-T

NM_000771.3(CYP2C9):c.482-334C>T

This variant was identified in 25 publications

View GRCh38 version.




Publications:


Pharmacogenomics in Psychiatry Practice: The Value and the Challenges.

International Journal Of Molecular Sciences
Alchakee, Aminah A; Ahmed, Munazza M; Eldohaji, Leen L; Alhaj, Hamid H; Saber-Ayad, Maha M
Publication Date: 2022-11-03

Variant appearance in text: rs4086116
PubMed Link: 36362270
Variant Present in the following documents:
  • Main text
  • ijms-23-13485.pdf
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Modified eQTL and Somatic DNA Segment Alterations in Esophageal Squamous Cell Carcinoma for Genes Related to Immunity, DNA Repair, and Inflammation.

Cancers
Yang, Howard H HH; Liu, Huaitian H; Hu, Nan N; Su, Hua H; Wang, Chaoyu C; Giffen, Carol C; Goldstein, Alisa M AM; Taylor, Philip R PR; Lee, Maxwell P MP
Publication Date: 2022-03-23

Variant appearance in text: rs4086116
PubMed Link: 35406404
Variant Present in the following documents:
  • cancers-14-01629.pdf
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Genomewide association analysis of warfarin dose requirements in Middle Eastern and North African populations.

Clinical And Translational Science
El Rouby, Nihal N; Shahin, Mohamed H MH; Bader, Loulia L; Khalifa, Sherief I SI; Elewa, Hazem H
Publication Date: 2022-02

Variant appearance in text: rs4086116
PubMed Link: 34729928
Variant Present in the following documents:
  • Main text
  • CTS-15-558.pdf
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Genome-Wide Association Study of VKORC1 and CYP2C9 on acenocoumarol dose, stroke recurrence and intracranial haemorrhage in Spain.

Scientific Reports
Cullell, Natalia N; Carrera, Caty C; Muiño, Elena E; Torres-Aguila, Nuria-Paz NP; Cárcel-Márquez, Jara J; González-Sánchez, Jonathan J; Gallego-Fabrega, Cristina C; Molina, Jessica J; Besora, Sarah S; Sotoca, Javier J; Buongiorno, Maria-Teresa MT; Jiménez-Conde, Jordi J; Giralt-Steinhauer, Eva E; de Torres-Chacón, Reyes R; Montaner, Joan J; Mancha, Fernando F; Cabezas, Juan A JA; Martí-Fàbregas, Joan J; Prats-Sánchez, Luis L; Camps-Renom, Pol P; Purroy, Francisco F; Cambray, Serafi S; Freijo, María Del Mar MDM; Vives-Bauzá, Cristòfol C; Tur, Silvia S; Font, Maria-Àngels MÀ; López-Cancio, Elena E; Hernandez-Perez, Maria M; Obach, Victor V; Calleja, Ana A; Arenillas, Juan J; Rodríguez-Yáñez, Manuel M; Castillo, José J; Sobrino, Tomas T; Fernández-Cádenas, Israel I; Krupinski, Jerzy J
Publication Date: 2020-02-18

Variant appearance in text: rs4086116
PubMed Link: 32071341
Variant Present in the following documents:
  • Main text
  • 41598_2020_Article_59641.pdf
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Association of CYP gene polymorphisms with breast cancer risk and prognostic factors in the Jordanian population.

Bmc Medical Genetics
Al-Eitan, Laith N LN; Rababa'h, Doaa M DM; Alghamdi, Mansour A MA; Khasawneh, Rame H RH
Publication Date: 2019-09-02

Variant appearance in text: rs4086116
PubMed Link: 31477036
Variant Present in the following documents:
  • Main text
  • 12881_2019_Article_884.pdf
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Effects of CYP2C9 and VKORC1 polymorphisms on warfarin sensitivity and responsiveness during the stabilization phase of therapy.

Saudi Pharmaceutical Journal : Spj : The Official Publication Of The Saudi Pharmaceutical Society
Al-Eitan, Laith N LN; Almasri, Ayah Y AY; Khasawneh, Rame H RH
Publication Date: 2019-05

Variant appearance in text: rs4086116
PubMed Link: 31061616
Variant Present in the following documents:
  • Main text
  • main.pdf
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Influence of Genetic Variants on Steady-State Etonogestrel Concentrations Among Contraceptive Implant Users.

Obstetrics And Gynecology
Lazorwitz, Aaron A; Aquilante, Christina L CL; Oreschak, Kris K; Sheeder, Jeanelle J; Guiahi, Maryam M; Teal, Stephanie S
Publication Date: 2019-04

Variant appearance in text: rs4086116
PubMed Link: 30870275
Variant Present in the following documents:
  • Main text
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Impact of CYP2C9 and VKORC1 Polymorphisms on Warfarin Sensitivity and Responsiveness in Jordanian Cardiovascular Patients during the Initiation Therapy.

Genes
Al-Eitan, Laith N LN; Almasri, Ayah Y AY; Khasawneh, Rame H RH
Publication Date: 2018-11-27

Variant appearance in text: rs4086116
PubMed Link: 30486437
Variant Present in the following documents:
  • Main text
  • genes-09-00578.pdf
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Intake of Vitamin K Antagonists and Worsening of Cardiac and Vascular Disease: Results From the Population-Based Gutenberg Health Study.

Journal Of The American Heart Association
Eggebrecht, Lisa L; Prochaska, Jürgen H JH; Schulz, Andreas A; Arnold, Natalie N; Jünger, Claus C; Göbel, Sebastian S; Laubert-Reh, Dagmar D; Binder, Harald H; Beutel, Manfred E ME; Pfeiffer, Nobert N; Blankenberg, Stefan S; Lackner, Karl J KJ; Spronk, Henri M HM; Ten Cate, Hugo H; Münzel, Thomas T; Wild, Philipp S PS
Publication Date: 2018-09-04

Variant appearance in text: rs4086116
PubMed Link: 30371151
Variant Present in the following documents:
  • Main text
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Whole genome sequencing identifies high-impact variants in well-known pharmacogenomic genes.

The Pharmacogenomics Journal
Choi, Jihoon J; Tantisira, Kelan G KG; Duan, Qing Ling QL
Publication Date: 2019-04

Variant appearance in text: rs4086116
PubMed Link: 30214008
Variant Present in the following documents:
  • NIHMS1503453-supplement-3.xlsx, sheet 1
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Pharmacogenetic studies with oral anticoagulants. Genome-wide association studies in vitamin K antagonist and direct oral anticoagulants.

Oncotarget
Cullell, Natalia N; Carrera, Caty C; Muiño, Elena E; Torres, Nuria N; Krupinski, Jerzy J; Fernandez-Cadenas, Israel I
Publication Date: 2018-06-26

Variant appearance in text: rs4086116
PubMed Link: 30018749
Variant Present in the following documents:
  • Main text
  • oncotarget-09-29238.pdf
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Genetic variation in the eicosanoid pathway is associated with non-small-cell lung cancer (NSCLC) survival.

Plos One
Sausville, Lindsay N LN; Jones, Carissa C CC; Aldrich, Melinda C MC; Blot, William J WJ; Pozzi, Ambra A; Williams, Scott M SM
Publication Date: 2017

Variant appearance in text: rs4086116
PubMed Link: 28704416
Variant Present in the following documents:
  • Main text
  • pone.0180471.pdf
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Influence of common and rare genetic variation on warfarin dose among African-Americans and European-Americans using the exome array.

Pharmacogenomics
Liu, Nianjun N; Irvin, Marguerite R MR; Zhi, Degui D; Patki, Amit A; Beasley, T Mark TM; Nickerson, Deborah A DA; Hill, Charles E CE; Chen, Jinbo J; Kimmel, Stephen E SE; Limdi, Nita A NA
Publication Date: 2017-07

Variant appearance in text: rs4086116
PubMed Link: 28686080
Variant Present in the following documents:
  • Main text
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Polymorphisms in CYP2C9 are associated with response to indomethacin among neonates with patent ductus arteriosus.

Pediatric Research
Smith, Caitlin J CJ; Ryckman, Kelli K KK; Bahr, Timothy M TM; Dagle, John M JM
Publication Date: 2017-11

Variant appearance in text: rs4086116
PubMed Link: 28609430
Variant Present in the following documents:
  • Main text
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Association of PON1, P2Y12 and COX1 with Recurrent Ischemic Events in Patients with Extracranial or Intracranial Stenting.

Plos One
Li, Xiao-Qing XQ; Ma, Ning N; Li, Xin-Gang XG; Wang, Bo B; Sun, Shu-Sen SS; Gao, Feng F; Mo, Da-Peng DP; Song, Li-Gang LG; Sun, Xuan X; Liu, Lian L; Zhao, Xing-Quan XQ; Wang, Yi-Long YL; Wang, Yong-Jun YJ; Zhao, Zhi-Gang ZG; Miao, Zhong-Rong ZR
Publication Date: 2016

Variant appearance in text: rs4086116
PubMed Link: 26870959
Variant Present in the following documents:
  • Main text
  • pone.0148891.pdf
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Genetic markers in the EET metabolic pathway are associated with outcomes in patients with aneurysmal subarachnoid hemorrhage.

Journal Of Cerebral Blood Flow And Metabolism : Official Journal Of The International Society Of Cerebral Blood Flow And Metabolism
Donnelly, Mark K MK; Conley, Yvette P YP; Crago, Elizabeth A EA; Ren, Dianxu D; Sherwood, Paula R PR; Balzer, Jeffery R JR; Poloyac, Samuel M SM
Publication Date: 2015-02

Variant appearance in text: rs4086116
PubMed Link: 25388680
Variant Present in the following documents:
  • Main text
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Diplotypes of CYP2C9 gene is associated with coronary artery disease in the Xinjiang Han population for women in China.

Lipids In Health And Disease
Fu, Zhenyan Z; Zhu, Qing Q; Ma, Yitong Y; Huang, Ding D; Pan, Shuo S; Xie, Xiang X; Liu, Fen F; Cha, Erdenbat E
Publication Date: 2014-09-02

Variant appearance in text: rs4086116
PubMed Link: 25182955
Variant Present in the following documents:
  • Main text
  • 12944_2014_Article_1157.pdf
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Association of CYP2C9*2 with bosentan-induced liver injury.

Clinical Pharmacology And Therapeutics
Markova, S M SM; De Marco, T T; Bendjilali, N N; Kobashigawa, E A EA; Mefford, J J; Sodhi, J J; Le, H H; Zhang, C C; Halladay, J J; Rettie, A E AE; Khojasteh, C C; McGlothlin, D D; Wu, A H B AH; Hsueh, W-C WC; Witte, J S JS; Schwartz, J B JB; Kroetz, D L DL
Publication Date: 2013-12

Variant appearance in text: rs4086116
PubMed Link: 23863877
Variant Present in the following documents:
  • Main text
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Effect of genetic variants, especially CYP2C9 and VKORC1, on the pharmacology of warfarin.

Seminars In Thrombosis And Hemostasis
Fung, Erik E; Patsopoulos, Nikolaos A NA; Belknap, Steven M SM; O'Rourke, Daniel J DJ; Robb, John F JF; Anderson, Jeffrey L JL; Shworak, Nicholas W NW; Moore, Jason H JH
Publication Date: 2012-11

Variant appearance in text: rs4086116
PubMed Link: 23041981
Variant Present in the following documents:
  • Main text
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Gene-drug interaction in stroke.

Stroke Research And Treatment
Amici, Serena S; Paciaroni, Maurizio M; Agnelli, Giancarlo G; Caso, Valeria V
Publication Date: 2011

Variant appearance in text: rs4086116
PubMed Link: 22135769
Variant Present in the following documents:
  • Main text
  • SRT2011-212485.pdf
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Selective serotonin re-uptake inhibiting antidepressants and the risk of overanticoagulation during acenocoumarol maintenance treatment.

British Journal Of Clinical Pharmacology
Teichert, Martina M; Visser, Loes E LE; Uitterlinden, Andrė G AG; Hofman, Albert A; Buhre, Peter J PJ; Straus, Sabine S; De Smet, Peter A G M PA; Stricker, Bruno H BH
Publication Date: 2011-11

Variant appearance in text: rs4086116
PubMed Link: 21545482
Variant Present in the following documents:
  • Main text
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Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms.

Plos Genetics
Zhai, Guangju G; Teumer, Alexander A; Stolk, Lisette L; Perry, John R B JR; Vandenput, Liesbeth L; Coviello, Andrea D AD; Koster, Annemarie A; Bell, Jordana T JT; Bhasin, Shalender S; Eriksson, Joel J; Eriksson, Anna A; Ernst, Florian F; Ferrucci, Luigi L; Frayling, Timothy M TM; Glass, Daniel D; Grundberg, Elin E; Haring, Robin R; Hedman, Asa K AK; Hofman, Albert A; Kiel, Douglas P DP; Kroemer, Heyo K HK; Liu, Yongmei Y; Lunetta, Kathryn L KL; Maggio, Marcello M; Lorentzon, Mattias M; Mangino, Massimo M; Melzer, David D; Miljkovic, Iva I; , ; Nica, Alexandra A; Penninx, Brenda W J H BW; Vasan, Ramachandran S RS; Rivadeneira, Fernando F; Small, Kerrin S KS; Soranzo, Nicole N; Uitterlinden, André G AG; Völzke, Henry H; Wilson, Scott G SG; Xi, Li L; Zhuang, Wei Vivian WV; Harris, Tamara B TB; Murabito, Joanne M JM; Ohlsson, Claes C; Murray, Anna A; de Jong, Frank H FH; Spector, Tim D TD; Wallaschofski, Henri H
Publication Date: 2011-04

Variant appearance in text: rs4086116
PubMed Link: 21533175
Variant Present in the following documents:
  • Main text
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An integrative method for scoring candidate genes from association studies: application to warfarin dosing.

Bmc Bioinformatics
Tatonetti, Nicholas P NP; Dudley, Joel T JT; Sagreiya, Hersh H; Butte, Atul J AJ; Altman, Russ B RB
Publication Date: 2010-10-28

Variant appearance in text: rs4086116
PubMed Link: 21044367
Variant Present in the following documents:
  • Main text
  • 1471-2105-11-S9-S9.pdf
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Genome-wide association studies in pharmacogenomics: successes and lessons.

Pharmacogenetics And Genomics
Motsinger-Reif, Alison A AA; Jorgenson, Eric E; Relling, Mary V MV; Kroetz, Deanna L DL; Weinshilboum, Richard R; Cox, Nancy J NJ; Roden, Dan M DM
Publication Date: 2013-08

Variant appearance in text: rs4086116
PubMed Link: 20639796
Variant Present in the following documents:
  • Main text
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A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose.

Blood
Cooper, Gregory M GM; Johnson, Julie A JA; Langaee, Taimour Y TY; Feng, Hua H; Stanaway, Ian B IB; Schwarz, Ute I UI; Ritchie, Marylyn D MD; Stein, C Michael CM; Roden, Dan M DM; Smith, Joshua D JD; Veenstra, David L DL; Rettie, Allan E AE; Rieder, Mark J MJ
Publication Date: 2008-08-15

Variant appearance in text: rs4086116
PubMed Link: 18535201
Variant Present in the following documents:
  • Main text
View BVdb publication page