Variant ID: 10-96741053-A-C

NM_000771.3(CYP2C9):c.1075A>C;(p.Ile359Leu)

This variant was identified in 530 publications




Publications:


Gene Polymorphisms Affecting the Pharmacokinetics and Pharmacodynamics of Donepezil Efficacy.

Frontiers In Pharmacology
J Lu, X Wang, L Wan, J Fu, Y Huo, Y Zhao, C Guo
Publication Date: 2020

Variant appearance in text: rs1057910
PMID: 32636753
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rs622342 in SLC22A1, CYP2C9*2 and CYP2C9*3 and Glycemic Response in Individuals with Type 2 Diabetes Mellitus Receiving Metformin/Sulfonylurea Combination Therapy: 6-Month Follow-Up Study.

Journal Of Personalized Medicine
K Naja, A Salami, S El Shamieh, R Fakhoury
Publication Date: 2020-06-20

Variant appearance in text: rs1057910
PMID: 32575674
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Genotype-Guided Dosing of Warfarin in Chinese Adults: A Multicenter Randomized Clinical Trial.

Circulation. Genomic And Precision Medicine
C Guo, Y Kuang, H Zhou, H Yuan, Q Pei, J Li, W Jiang, CM Ng, X Chen, Y Huo, Y Cui, X Wang, J Yu, X Sun, W Yu, P Chen, D Miao, W Liu, Z Yu, Z Ouyang, X Shi, C Lv, Z Peng, G Xiong, G Zeng, J Zeng, H Dai, J Peng, Y Zhang, F Xu, J Wu, X Chen, H Gong, Z Yang, X Wu, Q Fang, L Yang, H Li, H Tan, Z Huang, X Tang, Q Yang, S Tu, X Wang, Y Xiang, J Huang, X Wang, J Cai, S Jiang, L Huang, J Peng, L Gong, C Zou, G Yang
Publication Date: 2020-06-08

Variant appearance in text: rs1057910
PMID: 32510984
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Possible Genetic Determinants of Response to Phenytoin in a Group of Colombian Patients With Epilepsy.

Frontiers In Pharmacology
CA Calderon-Ospina, JM Galvez, C López-Cabra, N Morales, CM Restrepo, J Rodríguez, FA Aristizábal-Gutiérrez, A Velez-van-Meerbeke, P Laissue, DJ Fonseca-Mendoza
Publication Date: 2020

Variant appearance in text: CYP2C9: 1075A>C; rs1057910
PMID: 32457604
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Population Pharmacokinetic, Pharmacogenetic, and Pharmacodynamic Analysis of Cyclophosphamide in Ethiopian Breast Cancer Patients.

Frontiers In Pharmacology
JH Ahmed, E Makonnen, RK Bisaso, JK Mukonzo, A Fotoohi, A Aseffa, R Howe, M Hassan, E Aklillu
Publication Date: 2020

Variant appearance in text: rs1057910
PMID: 32390827
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The Identification of Admixture Patterns Could Refine Pharmacogenetic Counseling: Analysis of a Population-Based Sample in Mexico.

Frontiers In Pharmacology
JJ Martínez-Magaña, AD Genis-Mendoza, JA Villatoro Velázquez, B Camarena, R Martín Del Campo Sanchez, C Fleiz Bautista, M Bustos Gamiño, E Reséndiz, A Aguilar, ME Medina-Mora, H Nicolini
Publication Date: 2020

Variant appearance in text: N/A
PMID: 32390825
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The influence of genetic polymorphisms in drug metabolism enzymes and transporters on the pharmacokinetics of different fluvastatin formulations.

Asian Journal Of Pharmaceutical Sciences
Q Xiang, W Wu, N Zhao, C Li, J Xu, L Ma, X Zhang, Q Xie, Z Zhang, J Wang, W Xu, X Zhao, Y Cui
Publication Date: 2020-03

Variant appearance in text: rs1057910
PMID: 32373204
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Genetic polymorphisms of pharmacogenomic VIP variants in the Dai population from Yunnan province.

Molecular Genetics & Genomic Medicine
Y Cheng, R Dai, W Chen, Q Li, C Zhang, T Yang
Publication Date: 2020-04-29

Variant appearance in text: rs1057910
PMID: 32347657
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Variants in clopidogrel-relevant genes and early neurological deterioration in ischemic stroke patients receiving clopidogrel.

Bmc Neurology
X Yi, Q Zhou, Y Zhang, J Zhou, J Lin
Publication Date: 2020-04-28

Variant appearance in text: rs1057910
PMID: 32345264
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Genotype-guided warfarin dosing may benefit patients with mechanical aortic valve replacements: randomized controlled study.

Scientific Reports
KE Lee, J Yee, GY Lee, JE Chung, JM Seong, BC Chang, HS Gwak
Publication Date: 2020-04-24

Variant appearance in text: rs1057910
PMID: 32332930
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A Pharmacogenetically Guided Acenocoumarol Dosing Algorithm for Chilean Patients: A Discovery Cohort Study.

Frontiers In Pharmacology
A Roco, E Nieto, M Suárez, M Rojo, MP Bertoglia, G Verón, F Tamayo, A Arredondo, D Cruz, J Muñoz, G Bravo, P Salas, F Mejías, G Godoy, P Véliz, LA Quiñones
Publication Date: 2020

Variant appearance in text: CYP2C9: Ile359Leu; rs1057910
PMID: 32327994
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Effect of SAMe-TT2R2 score and genetic polymorphism on the quality of anticoagulation control in Qatari patients treated with warfarin.

Journal Of Thrombosis And Thrombolysis
H Elewa, I Qurishi, R Abouelhassan, S Abou Safrah, E Alhamoud, L Bader
Publication Date: 2020-04-10

Variant appearance in text: rs1057910
PMID: 32274641
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Functionally Significant Coumarin-Related Variant Alleles and Time to Therapeutic Range in Chilean Cardiovascular Patients.

Clinical And Applied Thrombosis/Hemostasis : Official Journal Of The International Academy Of Clinical And Applied Thrombosis/Hemostasis
M Rojo, AM Roco, M Suarez, MA Lavanderos, G Verón, MP Bertoglia, A Arredondo, E Nieto, JC Rubilar, F Tamayo, D Cruz, J Muñoz, G Bravo, P Salas, F Mejías, P Véliz, G Godoy, NM Varela, G Llull, LA Quiñones
Publication Date: 2020

Variant appearance in text: rs1057910
PMID: 32228310
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Implementation of a Renal Precision Medicine Program: Clinician Attitudes and Acceptance.

Life (Basel, Switzerland)
KM Spiech, PR Tripathy, AM Woodcock, NA Sheth, KS Collins, K Kannegolla, AD Sinha, AA Sharfuddin, VM Pratt, M Khalid, DS Hains, SM Moe, TC Skaar, RN Moorthi, MT Eadon
Publication Date: 2020-03-26

Variant appearance in text: rs1057910
PMID: 32224869
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A Pharmacogenomic Dissection of a Rosuvastatin-Induced Rhabdomyolysis Case Evokes the Polygenic Nature of Adverse Drug Reactions.

Pharmacogenomics And Personalized Medicine
CA Calderon-Ospina, M Hernández-Sómerson, AM García, A Mejia, C Tamayo-Agudelo, P Laissue, DJ Fonseca Mendoza
Publication Date: 2020

Variant appearance in text: CYP2C9: 1075A>C; Ile359Leu; rs1057910
PMID: 32184647
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Towards low cost, multiplex clinical genotyping: 4-fluorescent Kompetitive Allele-Specific PCR and its application on pharmacogenetics.

Plos One
W Suo, X Shi, S Xu, X Li, Y Lin
Publication Date: 2020

Variant appearance in text: rs1057910
PMID: 32176732
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CYP2C19*2 Polymorphism Is Associated with Impaired Oral Clearance of Gliclazide in Healthy Chinese.

Pharmacogenomics And Personalized Medicine
E Chow, EW Poon, BS Fok, JC Chan, B Tomlinson
Publication Date: 2019

Variant appearance in text: rs1057910
PMID: 32099442
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Analysis of protein missense alterations by combining sequence- and structure-based methods.

Molecular Genetics & Genomic Medicine
A Gyulkhandanyan, AR Rezaie, L Roumenina, N Lagarde, V Fremeaux-Bacchi, MA Miteva, BO Villoutreix
Publication Date: 2020-02-25

Variant appearance in text: CYP2C9: I359L
PMID: 32096919
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Genome-Wide Association Study of VKORC1 and CYP2C9 on acenocoumarol dose, stroke recurrence and intracranial haemorrhage in Spain.

Scientific Reports
N Cullell, C Carrera, E Muiño, NP Torres-Aguila, J Cárcel-Márquez, J González-Sánchez, C Gallego-Fabrega, J Molina, S Besora, J Sotoca, MT Buongiorno, J Jiménez-Conde, E Giralt-Steinhauer, R de Torres-Chacón, J Montaner, F Mancha, JA Cabezas, J Martí-Fàbregas, L Prats-Sánchez, P Camps-Renom, F Purroy, S Cambray, MDM Freijo, C Vives-Bauzá, S Tur, MÀ Font, E López-Cancio, M Hernandez-Perez, V Obach, A Calleja, J Arenillas, M Rodríguez-Yáñez, J Castillo, T Sobrino, I Fernández-Cádenas, J Krupinski
Publication Date: 2020-02-18

Variant appearance in text: N/A
PMID: 32071341
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Phenprocoumon Dose Requirements, Dose Stability and Time in Therapeutic Range in Elderly Patients With CYP2C9 and VKORC1 Polymorphisms.

Frontiers In Pharmacology
KL Schneider, M Kunst, AK Leuchs, M Böhme, K Weckbecker, K Kastenmüller, M Bleckwenn, S Holdenrieder, C Coch, G Hartmann, JC Stingl
Publication Date: 2019

Variant appearance in text: rs1057910
PMID: 32047440
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Effect of Gene-Based Warfarin Dosing on Anticoagulation Control and Clinical Events in a Real-World Setting.

Frontiers In Pharmacology
J Zhang, T Wu, W Chen, J Fu, X Xia, L Chen
Publication Date: 2019

Variant appearance in text: rs1057910
PMID: 32038232
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The Effect of UGT1A9, CYP2B6 and CYP2C9 Genes Polymorphism on Propofol Pharmacokinetics in Children.

Pharmacogenomics And Personalized Medicine
D Pavlovic, I Budic, T Jevtovic Stoimenov, D Stokanovic, V Marjanovic, M Stevic, M Slavkovic, D Simic
Publication Date: 2020

Variant appearance in text: CYP2C9: 1075A>C; I359L; rs1057910
PMID: 32021384
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Pharmacogene Variation in Thai Plasmodium vivax Relapse Patients Treated with a Combination of Primaquine and Chloroquine.

Pharmacogenomics And Personalized Medicine
M Chamnanphon, A Gaedigk, A Puangpetch, E Pasomsub, W Chantratita, RJ Longley, J Sattabongkot, P Chariyavilaskul, C Sukasem
Publication Date: 2020

Variant appearance in text: CYP2C9: 1075A>C; rs1057910
PMID: 32021383
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Heterogeneity in the distribution of 159 drug-response related SNPs in world populations and their genetic relatedness.

Plos One
T Ahsan, NJ Urmi, AA Sajib
Publication Date: 2020

Variant appearance in text: rs1057910
PMID: 31971968
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Pharmacogenomic network analysis of the gene-drug interaction landscape underlying drug disposition.

Computational And Structural Biotechnology Journal
Y Zhou, VM Lauschke
Publication Date: 2020

Variant appearance in text: rs1057910
PMID: 31890144
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Genetic risk assessment towards warfarin application: Saudi Arabia study with a potential to predict and prevent side effects.

Saudi Journal Of Biological Sciences
FI Al-Saikhan
Publication Date: 2020-01

Variant appearance in text: rs1057910
PMID: 31889870
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Olfactory-Related Quality of Life in Multiple Chemical Sensitivity: A Genetic-Acquired Factors Model.

International Journal Of Molecular Sciences
A Micarelli, A Cormano, D Caccamo, M Alessandrini
Publication Date: 2019-12-25

Variant appearance in text: CYP2C9: I359L; rs1057910
PMID: 31881664
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Effects of Polymorphisms in Myc-Related Genes on Bleeding Complications in Patients with Stable Warfarin Responses.

Cardiovascular Therapeutics
J Yee, W Kim, BC Chang, JE Chung, KE Lee, HS Gwak
Publication Date: 2019

Variant appearance in text: rs1057910
PMID: 31772606
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Clinical Utility of Pharmacogene Panel-Based Testing in Patients Undergoing Percutaneous Coronary Intervention (PCI).

Clinical And Translational Science
N El Rouby, A Alrwisan, T Langaee, G Lipori, DJ Angiolillo, F Franchi, A Riva, A Elsey, JA Johnson, LH Cavallari, AG Winterstein
Publication Date: 2019-11-23

Variant appearance in text: CYP2C9: 1075A>C; rs1057910
PMID: 31758664
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Variation in Actionable Pharmacogenetic Markers in Natives and Mestizos From Mexico.

Frontiers In Pharmacology
V Gonzalez-Covarrubias, M Morales-Franco, OF Cruz-Correa, A Martínez-Hernández, H García-Ortíz, F Barajas-Olmos, AD Genis-Mendoza, JJ Martínez-Magaña, H Nicolini, L Orozco, X Soberón
Publication Date: 2019

Variant appearance in text: rs1057910
PMID: 31649539
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The Three Ps: Psychiatry, Pharmacy, and Pharmacogenomics, a Brief Report From New Zealand.

Frontiers In Psychiatry
SDS Maggo, KLV Sycamore, AL Miller, MA Kennedy
Publication Date: 2019

Variant appearance in text: rs1057910
PMID: 31616328
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Steroid hormone-related polymorphisms associate with the development of bone erosions in rheumatoid arthritis and help to predict disease progression: Results from the REPAIR consortium.

Scientific Reports
JM Sánchez-Maldonado, R Cáliz, L Canet, RT Horst, O Bakker, AA den Broeder, M Martínez-Bueno, H Canhão, A Rodríguez-Ramos, CB Lupiañez, MJ Soto-Pino, A García, E Pérez-Pampin, A González-Utrilla, A Escudero, J Segura-Catena, RT Netea-Maier, MÁ Ferrer, E Collantes-Estevez, MÁ López Nevot, Y Li, M Jurado, JE Fonseca, MG Netea, MJH Coenen, J Sainz
Publication Date: 2019-10-15

Variant appearance in text: CYP2C9: I359L; rs1057910
PMID: 31616008
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Role of Biological Markers for Cerebral Bleeding Risk STRATification in Patients with Atrial Fibrillation on Oral Anticoagulants for Primary or Secondary Prevention of Ischemic Stroke (Strat-AF Study): Study Design and Methodology.

Medicina (Kaunas, Lithuania)
A Poggesi, C Barbato, F Galmozzi, E Camilleri, F Cesari, S Chiti, S Diciotti, S Galora, B Giusti, AM Gori, C Marzi, A Melone, D Mistri, F Pescini, G Pracucci, V Rinnoci, C Sarti, E Fainardi, R Marcucci, E Salvadori
Publication Date: 2019-09-23

Variant appearance in text: rs1057910
PMID: 31548494
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Risk Factors for Recurrent Colorectal Polyps.

Gut And Liver
Y Hao, Y Wang, M Qi, X He, Y Zhu, J Hong
Publication Date: 2019-09-25

Variant appearance in text: rs1057910
PMID: 31547641
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CYP2D6 Genotype Predicts Plasma Concentrations of Tamoxifen Metabolites in Ethiopian Breast Cancer Patients.

Cancers
JH Ahmed, E Makonnen, A Fotoohi, A Aseffa, R Howe, E Aklillu
Publication Date: 2019-09-12

Variant appearance in text: rs1057910
PMID: 31547390
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Pharmacogenomic genotypes define genetic ancestry in patients and enable population-specific genomic implementation.

The Pharmacogenomics Journal
W Hernandez, K Danahey, X Pei, KJ Yeo, E Leung, SL Volchenboum, MJ Ratain, DO Meltzer, BE Stranger, MA Perera, PH O'Donnell
Publication Date: 2019-09-11

Variant appearance in text: rs1057910
PMID: 31506565
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Clinical Model for Predicting Warfarin Sensitivity.

Scientific Reports
Z Ma, G Cheng, P Wang, B Khalighi, K Khalighi
Publication Date: 2019-09-06

Variant appearance in text: rs1057910
PMID: 31492893
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CYP2C9*2 is associated with indomethacin treatment failure for patent ductus arteriosus.

Pharmacogenomics
SR Rooney, EL Shelton, I Aka, CM Shaffer, RI Clyman, JM Dagle, K Ryckman, TR Lewis, J Reese, SL Van Driest, PJ Kannankeril
Publication Date: 2019-08

Variant appearance in text: rs1057910
PMID: 31486736
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Functional Characterization of Pharmcogenetic Variants of Human Cytochrome P450 2C9 in Korean Populations.

Biomolecules & Therapeutics
MA Cho, JG Yoon, V Kim, H Kim, R Lee, MG Lee, D Kim
Publication Date: 2019-11-01

Variant appearance in text: rs1057910
PMID: 31484472
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Assessing the clinical impact of CYP2C9 pharmacogenetic variation on phenytoin prescribing practice and patient response in an integrated health system.

Pharmacogenetics And Genomics
AE Fohner, DK Ranatunga, KK Thai, BL Lawson, N Risch, A Oni-Orisan, AT Jelalian, AE Rettie, VX Liu, CA Schaefer
Publication Date: 2019-10

Variant appearance in text: rs1057910
PMID: 31461080
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Polymorphisms of CYP2C9*2, CYP2C9*3 and VKORC1 genes related to time in therapeutic range in patients with atrial fibrillation using warfarin.

The Application Of Clinical Genetics
MMBM da Silveira, LA Melo, FMF Gomes, LJCBDR Andrade, IP Serur, ICV Piscoya, RM Gueiros, K Palmeira do Ó, RE de Lima, VAE Brasileiro, LRS Vasconcelos, DC Sobral Filho
Publication Date: 2019

Variant appearance in text: rs1057910
PMID: 31447576
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Harmonizing Clinical Sequencing and Interpretation for the eMERGE III Network.

American Journal Of Human Genetics
,
Publication Date: 2019-09-05

Variant appearance in text: N/A
PMID: 31447099
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Preliminary outcomes of preemptive warfarin pharmacogenetic testing at a large rural healthcare center.

American Journal Of Health-System Pharmacy : Ajhp : Official Journal Of The American Society Of Health-System Pharmacists
E Leary, M Brilliant, P Peissig, S Griesbach
Publication Date: 2019-02-21

Variant appearance in text: CYP2C9: I359L; rs1057910
PMID: 31415684
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Pharmacogenomic considerations for medications in the perioperative setting.

Pharmacogenomics
EH Jhun, JL Apfelbaum, DM Dickerson, S Shahul, R Knoebel, K Danahey, MJ Ratain, PH O'Donnell
Publication Date: 2019-07

Variant appearance in text: CYP2C9: I359L; rs1057910
PMID: 31411557
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Genetic polymorphisms analysis of pharmacogenomic VIP variants in Bai ethnic group from China.

Molecular Genetics & Genomic Medicine
W Chen, H Ding, Y Cheng, Q Li, R Dai, X Yang, C Zhang
Publication Date: 2019-09

Variant appearance in text: rs1057910
PMID: 31361092
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Association between four microRNA binding site-related polymorphisms and the risk of warfarin-induced bleeding complications.

Excli Journal
M Hosseindokht, M Boroumand, R Salehi, A Mandegary, A Hajhosseini Talasaz, L Pourgholi, H Zare, S Ziaee, M Sharifi
Publication Date: 2019

Variant appearance in text: rs1057910
PMID: 31338002
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Analyzing and Reanalyzing the Genome: Findings from the MedSeq Project.

American Journal Of Human Genetics
K Machini, O Ceyhan-Birsoy, DR Azzariti, H Sharma, P Rossetti, L Mahanta, L Hutchinson, H McLaughlin, , RC Green, M Lebo, HL Rehm
Publication Date: 2019-07-03

Variant appearance in text: rs1057910
PMID: 31256874
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High and variable population prevalence of HLA-B*56:02 in indigenous Australians and relation to phenytoin-associated drug reaction with eosinophilia and systemic symptoms.

British Journal Of Clinical Pharmacology
AA Somogyi, DT Barratt, EJ Phillips, K Moore, F Ilyas, GM Gabb
Publication Date: 2019-09

Variant appearance in text: rs1057910
PMID: 31206740
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Genetic variations in the transcription factors GATA4 and GATA6 and bleeding complications in patients receiving warfarin therapy.

Drug Design, Development And Therapy
J Yee, W Kim, BC Chang, JE Chung, KE Lee, HS Gwak
Publication Date: 2019

Variant appearance in text: rs1057910
PMID: 31190750
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Population study of thrombophilic markers and pharmacogenetic markers of warfarin prevalence in Bosnia and Herzegovina.

Croatian Medical Journal
A Ašić, R Salazar, N Storm, S Doğan, W Höppner, D Marjanović, D Primorac
Publication Date: 2019-06-13

Variant appearance in text: CYP2C9: 1075A>C
PMID: 31187948
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Targeted ultra-deep sequencing of a South African Bantu-speaking cohort to comprehensively map and characterize common and novel variants in 65 pharmacologically-related genes.

Pharmacogenetics And Genomics
S Tshabalala, A Choudhury, N Beeton-Kempen, N Martinson, M Ramsay, D Mancama
Publication Date: 2019-09

Variant appearance in text: rs1057910
PMID: 31162291
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Targeted next generation sequencing as a tool for precision medicine.

Bmc Medical Genomics
M Gulilat, T Lamb, WA Teft, J Wang, JS Dron, JF Robinson, RG Tirona, RA Hegele, RB Kim, UI Schwarz
Publication Date: 2019-06-03

Variant appearance in text: CYP2C9: I359L; rs1057910
PMID: 31159795
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CYP2J2∗7 Genotype Predicts Risk of Chemotherapy-Induced Hematologic Toxicity and Reduced Relative Dose Intensity in Ethiopian Breast Cancer Patients.

Frontiers In Pharmacology
JH Ahmed, E Makonnen, G Yimer, D Seifu, A Bekele, M Assefa, A Aseffa, R Howe, A Fotoohi, M Hassan, E Aklillu
Publication Date: 2019

Variant appearance in text: N/A
PMID: 31139078
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Between a rock and a hard place: a high-risk patient with resistance to multiple P2Y12 antagonists.

Pharmacogenomics
BH Davis, C Dillon, A Cai, LA Williams Iii, SV Pamboukian, NA Limdi
Publication Date: 2019-05

Variant appearance in text: CYP2C9: 1075A>C; rs1057910
PMID: 31124414
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Impact of gene polymorphism on the initiation and maintenance phases of warfarin therapy in Chinese patients undergoing heart valve replacement.

American Journal Of Translational Research
J Liu, H Guan, L Zhou, Y Cui, W Cao, L Wang
Publication Date: 2019

Variant appearance in text: rs1057910
PMID: 31105858
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Optimising migraine treatment: from drug-drug interactions to personalized medicine.

The Journal Of Headache And Pain
LM Pomes, M Guglielmetti, E Bertamino, M Simmaco, M Borro, P Martelletti
Publication Date: 2019-05-17

Variant appearance in text: rs1057910
PMID: 31101004
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Implications of genetic variation of common Drug Metabolizing Enzymes and ABC Transporters among the Pakistani Population.

Scientific Reports
NA Afsar, H Bruckmueller, AN Werk, MK Nisar, HR Ahmad, I Cascorbi
Publication Date: 2019-05-13

Variant appearance in text: CYP2C9: 1075A>C; rs1057910
PMID: 31086207
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Recommendations for Clinical CYP2C9 Genotyping Allele Selection: A Joint Recommendation of the Association for Molecular Pathology and College of American Pathologists.

The Journal Of Molecular Diagnostics : Jmd
VM Pratt, LH Cavallari, AL Del Tredici, H Hachad, Y Ji, AM Moyer, SA Scott, M Whirl-Carrillo, KE Weck
Publication Date: 2019-09

Variant appearance in text: CYP2C9: 1075A>C; Ile359Leu; rs1057910
PMID: 31075510
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Effects of CYP2C9 and VKORC1 polymorphisms on warfarin sensitivity and responsiveness during the stabilization phase of therapy.

Saudi Pharmaceutical Journal : Spj : The Official Publication Of The Saudi Pharmaceutical Society
LN Al-Eitan, AY Almasri, RH Khasawneh
Publication Date: 2019-05

Variant appearance in text: rs1057910
PMID: 31061616
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The Advantages and Challenges of Diversity in Pharmacogenomics: Can Minority Populations Bring Us Closer to Implementation?

Clinical Pharmacology And Therapeutics
H Zhang, T De, Y Zhong, MA Perera
Publication Date: 2019-08

Variant appearance in text: rs1057910
PMID: 31038731
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Secondary actionable findings identified by exome sequencing: expected impact on the organisation of care from the study of 700 consecutive tests.

European Journal Of Human Genetics : Ejhg
C Thauvin-Robinet, J Thevenon, S Nambot, J Delanne, P Kuentz, AL Bruel, A Chassagne, E Cretin, A Pelissier, C Peyron, E Gautier, D Lehalle, N Jean-Marçais, P Callier, AL Mosca-Boidron, A Vitobello, A Sorlin, F Tran Mau-Them, C Philippe, P Vabres, L Demougeot, C Poé, T Jouan, M Chevarin, M Lefebvre, M Bardou, E Tisserant, M Luu, C Binquet, JF Deleuze, C Verstuyft, Y Duffourd, L Faivre
Publication Date: 2019-08

Variant appearance in text: rs1057910
PMID: 31019283
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Enantiospecific Pharmacogenomics of Fluvastatin.

Clinical Pharmacology And Therapeutics
P Hirvensalo, A Tornio, M Neuvonen, W Kiander, H Kidron, M Paile-Hyvärinen, T Tapaninen, JT Backman, M Niemi
Publication Date: 2019-09

Variant appearance in text: CYP2C9: 1075A>C; Ile359Leu; rs1057910
PMID: 30989645
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Population Pharmacogenomics for Precision Public Health in Colombia.

Frontiers In Genetics
SD Nagar, AM Moreno, ET Norris, L Rishishwar, AB Conley, KL O'Neal, S Vélez-Gómez, C Montes-Rodríguez, WV Jaraba-Álvarez, I Torres, MA Medina-Rivas, A Valderrama-Aguirre, IK Jordan, JE Gallo
Publication Date: 2019

Variant appearance in text: rs1057910
PMID: 30967898
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Impact of a variable number tandem repeat in the CYP2C9 promoter on warfarin sensitivity and responsiveness in Jordanians with cardiovascular disease.

Pharmacogenomics And Personalized Medicine
LN Al-Eitan, AY Almasri, SO Al-Habahbeh
Publication Date: 2019

Variant appearance in text: CYP2C9: Ile359Leu
PMID: 30962704
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Implementation of genotype-guided dosing of warfarin with point-of-care genetic testing in three UK clinics: a matched cohort study.

Bmc Medicine
AL Jorgensen, C Prince, G Fitzgerald, A Hanson, J Downing, J Reynolds, JE Zhang, A Alfirevic, M Pirmohamed
Publication Date: 2019-04-08

Variant appearance in text: rs1057910
PMID: 30961588
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Pharmacogenetics in the Treatment of Cardiovascular Diseases and Its Current Progress Regarding Implementation in the Clinical Routine.

Genes
CL Dávila-Fajardo, X Díaz-Villamarín, A Antúnez-Rodríguez, AE Fernández-Gómez, P García-Navas, LJ Martínez-González, JA Dávila-Fajardo, JC Barrera
Publication Date: 2019-04-01

Variant appearance in text: rs1057910
PMID: 30939847
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Warfarin dose requirement in patients having severe thrombosis or thrombophilia.

British Journal Of Clinical Pharmacology
TA Helin, L Joutsi-Korhonen, H Asmundela, M Niemi, A Orpana, R Lassila
Publication Date: 2019-08

Variant appearance in text: CYP2C9: 1075A>C; rs1057910
PMID: 30933373
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Actionable Pharmacogenetic Variation in the Slovenian Genomic Database.

Frontiers In Pharmacology
K Hočevar, A Maver, B Peterlin
Publication Date: 2019

Variant appearance in text: CYP2C9: 1075A>C; Ile359Leu
PMID: 30930780
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Influence of Genetic Variants on Steady-State Etonogestrel Concentrations Among Contraceptive Implant Users.

Obstetrics And Gynecology
A Lazorwitz, CL Aquilante, K Oreschak, J Sheeder, M Guiahi, S Teal
Publication Date: 2019-04

Variant appearance in text: rs1057910
PMID: 30870275
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VKORC1 and CYP2C9 Polymorphisms: A Case Report in a Dutch Family with Pulmonary Fibrosis.

International Journal Of Molecular Sciences
P Wijnen, M Drent, O Bekers, J Verschakelen, A Bast
Publication Date: 2019-03-07

Variant appearance in text: rs1057910
PMID: 30866412
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VKORC1 and Novel CYP2C9 Variation Predict Warfarin Response in Alaska Native and American Indian People.

Clinical And Translational Science
LM Henderson, RF Robinson, L Ray, BA Khan, T Li, DA Dillard, BD Schilling, M Mosley, PL Janssen, AE Fohner, AE Rettie, KE Thummel, TA Thornton, DL Veenstra
Publication Date: 2019-05

Variant appearance in text: rs1057910
PMID: 30821933
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High penetrance of acute intermittent porphyria in a Spanish founder mutation population and CYP2D6 genotype as a susceptibility factor.

Orphanet Journal Of Rare Diseases
M Barreda-Sánchez, J Buendía-Martínez, G Glover-López, C Carazo-Díaz, MJ Ballesta-Martínez, V López-González, MJ Sánchez-Soler, L Rodriguez-Peña, AT Serrano-Antón, R Gil-Ferrer, MDC Martínez-Romero, P Carbonell-Meseguer, E Guillén-Navarro
Publication Date: 2019-02-26

Variant appearance in text: rs1057910
PMID: 30808393
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Novel genetic and epigenetic factors of importance for inter-individual differences in drug disposition, response and toxicity.

Pharmacology & Therapeutics
VM Lauschke, Y Zhou, M Ingelman-Sundberg
Publication Date: 2019-05

Variant appearance in text: rs1057910
PMID: 30677473
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Pharmacogenomics of Novel Direct Oral Anticoagulants: Newly Identified Genes and Genetic Variants.

Journal Of Personalized Medicine
SH Kanuri, RP Kreutz
Publication Date: 2019-01-17

Variant appearance in text: rs1057910
PMID: 30658513
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Association between genetic polymorphisms of CYP2C9 and VKORC1 and safety and efficacy of warfarin: Results of a 5 years audit.

Indian Heart Journal
M Biswas, SR Bendkhale, SP Deshpande, SJ Thaker, DV Kulkarni, SJ Bhatia, AG Rajadhyaksha, NJ Gogtay, UM Thatte
Publication Date: 2018-12

Variant appearance in text: CYP2C9: Ile359Leu; rs1057910
PMID: 30595245
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OATP1B3 (699G>A) and CYP2C9*2, *3 significantly influenced the transport and metabolism of glibenclamide and glipizide.

Scientific Reports
F Yang, L Liu, L Chen, M Liu, F Liu, Y Xiong, X Hu, C Xia
Publication Date: 2018-12-24

Variant appearance in text: CYP2C9: Ile359Leu
PMID: 30584236
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Pharmacogenetics of type 2 diabetes mellitus, the route toward tailored medicine.

Diabetes/Metabolism Research And Reviews
GC Mannino, F Andreozzi, G Sesti
Publication Date: 2019-03

Variant appearance in text: CYP2C9: Ile359Leu; rs1057910
PMID: 30515958
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Effect of CYP4F2, VKORC1, and CYP2C9 in Influencing Coumarin Dose: A Single-Patient Data Meta-Analysis in More Than 15,000 Individuals.

Clinical Pharmacology And Therapeutics
E Danese, S Raimondi, M Montagnana, A Tagetti, T Langaee, P Borgiani, C Ciccacci, AJ Carcas, AM Borobia, HY Tong, C Dávila-Fajardo, M Rodrigues Botton, S Bourgeois, P Deloukas, MD Caldwell, JK Burmester, RL Berg, LH Cavallari, K Drozda, M Huang, LZ Zhao, HJ Cen, R Gonzalez-Conejero, V Roldan, Y Nakamura, T Mushiroda, IY Gong, RB Kim, K Hirai, K Itoh, C Isaza, L Beltrán, E Jiménez-Varo, M Cañadas-Garre, A Giontella, MK Kringen, KBF Haug, HS Gwak, KE Lee, P Minuz, MTM Lee, SA Lubitz, S Scott, C Mazzaccara, L Sacchetti, E Genç, M Özer, A Pathare, R Krishnamoorthy, A Paldi, V Siguret, MA Loriot, VK Kutala, G Suarez-Kurtz, J Perini, JC Denny, AH Ramirez, B Mittal, SS Rathore, H Sagreiya, R Altman, MHA Shahin, SI Khalifa, NA Limdi, C Rivers, A Shendre, C Dillon, IM Suriapranata, HH Zhou, SL Tan, V Tatarunas, V Lesauskaite, Y Zhang, AH Maitland-van der Zee, TI Verhoef, A de Boer, M Taljaard, CF Zambon, V Pengo, JE Zhang, M Pirmohamed, JA Johnson, C Fava
Publication Date: 2019-06

Variant appearance in text: CYP2C9: I359L; rs1057910
PMID: 30506689
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Standardized Biogeographic Grouping System for Annotating Populations in Pharmacogenetic Research.

Clinical Pharmacology And Therapeutics
R Huddart, AE Fohner, M Whirl-Carrillo, GL Wojcik, CR Gignoux, AB Popejoy, CD Bustamante, RB Altman, TE Klein
Publication Date: 2019-05

Variant appearance in text: rs1057910
PMID: 30506572
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Analytical validity of a genotyping assay for use with personalized antihypertensive and chronic kidney disease therapy.

Pharmacogenetics And Genomics
KS Collins, VM Pratt, WM Stansberry, EB Medeiros, K Kannegolla, M Swart, TC Skaar, AB Chapman, BS Decker, RN Moorthi, MT Eadon
Publication Date: 2019-01

Variant appearance in text: rs1057910
PMID: 30489456
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Impact of CYP2C9 and VKORC1 Polymorphisms on Warfarin Sensitivity and Responsiveness in Jordanian Cardiovascular Patients during the Initiation Therapy.

Genes
LN Al-Eitan, AY Almasri, RH Khasawneh
Publication Date: 2018-11-27

Variant appearance in text: CYP2C9: I359L; rs1057910
PMID: 30486437
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CYP genetic variants and toxicity related to anti-tubercular agents: a systematic review and meta-analysis.

Systematic Reviews
M Richardson, J Kirkham, K Dwan, DJ Sloan, G Davies, AL Jorgensen
Publication Date: 2018-11-20

Variant appearance in text: rs1057910
PMID: 30458875
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Warfarin maintenance dose associated with genetic polymorphisms of CYP2C9.

Hippokratia
E Khaleqsefat, M Khalaj-Kondori, B Jabbarpour, E Battaloğlu
Publication Date: 2017

Variant appearance in text: CYP2C9: Ile359Leu
PMID: 30455562
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Low Performance of a Clinical-Genetic Model in the Estimation of Time in Therapeutic Range in Acenocoumarol-Adherent Patients with Nonvalvular Atrial Fibrillation: The Quality of Anticoagulation Challenge.

Biomed Research International
S Wasniewski, L Consuegra-Sánchez, P Conesa-Zamora, L García de Guadiana-Romualdo, P Ramos-Ruiz, M Merelo-Nicolás, FG Clavel-Ruipérez, B Alburquerque-González, F Soria-Arcos, JA Castillo-Moreno
Publication Date: 2018

Variant appearance in text: rs1057910
PMID: 30417015
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Creating and validating a warfarin pharmacogenetic dosing algorithm for Colombian patients.

Pharmacogenomics And Personalized Medicine
JM Galvez, CM Restrepo, NC Contreras, C Alvarado, CA Calderón-Ospina, N Peña, RA Cifuentes, D Duarte, P Laissue, DJ Fonseca
Publication Date: 2018

Variant appearance in text: CYP2C9: 1075A>C; rs1057910
PMID: 30410385
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K-variant BCHE and pesticide exposure: Gene-environment interactions in a case-control study of Parkinson's disease in Egypt.

Scientific Reports
TW Rösler, M Salama, AS Shalash, EM Khedr, A El-Tantawy, G Fawi, A El-Motayam, E El-Seidy, M El-Sherif, M El-Gamal, M Moharram, M El-Kattan, M Abdel-Naby, S Ashour, U Müller, A Dempfle, G Kuhlenbäumer, GU Höglinger
Publication Date: 2018-11-08

Variant appearance in text: rs1057910
PMID: 30410011
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The significance of enzyme and transporter polymorphisms for imatinib plasma levels and achieving an optimal response in chronic myeloid leukemia patients.

Archives Of Medical Science : Ams
P Belohlavkova, F Vrbacky, J Voglova, Z Racil, D Zackova, K Hrochova, J Malakova, J Mayer, P Zak
Publication Date: 2018-10

Variant appearance in text: rs1057910
PMID: 30393497
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Genetic Polymorphisms and In Silico Mutagenesis Analyses of CYP2C9, CYP2D6, and CYPOR Genes in the Pakistani Population.

Genes
S Ahmed, J Zhou, Z Zhou, SQ Chen
Publication Date: 2018-10-22

Variant appearance in text: CYP2C9: I359L; rs1057910
PMID: 30360443
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Association of Genetic Variants With Warfarin-Associated Bleeding Among Patients of African Descent.

Jama
T De, C Alarcon, W Hernandez, I Liko, LH Cavallari, JD Duarte, MA Perera
Publication Date: 2018-10-23

Variant appearance in text: rs1057910
PMID: 30357299
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Frequencies of poor metabolizer alleles of 12 pharmacogenomic actionable genes in Punjabi Sikhs of Indian Origin.

Scientific Reports
DK Sanghera, C Bejar, B Sapkota, GS Wander, S Ralhan
Publication Date: 2018-10-24

Variant appearance in text: rs1057910
PMID: 30356105
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Pharmacogenetics of warfarin dosing in patients of African and European ancestry.

Pharmacogenomics
A Shendre, C Dillon, NA Limdi
Publication Date: 2018-11

Variant appearance in text: rs1057910
PMID: 30345882
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Influence of SLCO1B1 in gastric cancer patients treated with EOF chemotherapy.

Oncology Letters
W Feng, X Liu, X Zhao, M Huang, W Guo, J Yin, Z Chen, X Zhu
Publication Date: 2018-10

Variant appearance in text: N/A
PMID: 30214584
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Establishment of a Han Chinese-specific pharmacogenetic-guided warfarin dosing algorithm.

Medicine
L Pei, X Tian, Y Long, W Nan, M Jia, R Qiao, J Zhang
Publication Date: 2018-09

Variant appearance in text: rs1057910
PMID: 30200121
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Effect of CYP2C9 Polymorphisms on the Pharmacokinetics of Indomethacin During Pregnancy.

European Journal Of Drug Metabolism And Pharmacokinetics
M Shah, M Xu, P Shah, X Wang, SM Clark, M Costantine, HA West, TN Nanovskaya, MS Ahmed, SZ Abdel-Rahman, R Venkataramanan, SN Caritis, GDV Hankins, E Rytting
Publication Date: 2019-02

Variant appearance in text: CYP2C9: I359L; rs1057910
PMID: 30159654
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Effects of Khat (Catha edulis) use on catalytic activities of major drug-metabolizing cytochrome P450 enzymes and implication of pharmacogenetic variations.

Scientific Reports
W Bedada, F de Andrés, E Engidawork, J Hussein, A LLerena, E Aklillu
Publication Date: 2018-08-24

Variant appearance in text: rs1057910
PMID: 30143732
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Cytochrome P450: Polymorphisms and Roles in Cancer, Diabetes and Atherosclerosis

Asian Pacific Journal Of Cancer Prevention : Apjcp
I Elfaki, R Mir, FM Almutairi, FMA Duhier
Publication Date: 2018-08-24

Variant appearance in text: N/A
PMID: 30139042
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The role of pharmacogenetics of cytochrome P450s in phenytoin-induced DRESS syndrome.

Central-European Journal Of Immunology
Ü Yaşar
Publication Date: 2018

Variant appearance in text: rs1057910
PMID: 30135636
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Height, VKORC1 1173, and CYP2C9 Genotypes Determine Warfarin Dose for Pediatric Patients with Kawasaki Disease in Southwest China.

Pediatric Cardiology
D Yang, H Kuang, Y Zhou, C Cai, T Lu
Publication Date: 2019-01

Variant appearance in text: rs1057910
PMID: 30121860
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A phase 1 trial evaluating thioridazine in combination with cytarabine in patients with acute myeloid leukemia.

Blood Advances
L Aslostovar, AL Boyd, M Almakadi, TJ Collins, DP Leong, RG Tirona, RB Kim, JA Julian, A Xenocostas, B Leber, MN Levine, R Foley, M Bhatia
Publication Date: 2018-08-14

Variant appearance in text: rs1057910
PMID: 30093531
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Alternative transcript annotations:

Transcript cDNA Protein Consequence Exon Intron
ENST00000260682.6 c.1075A>C p.Ile359Leu missense_variant 7/9 -
NM_000771.4 c.1075A>C p.Ile359Leu missense_variant 7/9 -