CYP2C8 c.416G>A ;(p.R139K)

Variant ID: 10-96827030-C-T

NM_000770.3(CYP2C8):c.416G>A;(p.R139K)

This variant was identified in 157 publications

View GRCh38 version.




Publications:


Genetic variations that influence paclitaxel pharmacokinetics and intracellular effects that may contribute to chemotherapy-induced neuropathy: A narrative review.

Frontiers In Pain Research (Lausanne, Switzerland)
Johnson, Ken B KB; Sharma, Anukriti A; Henry, N Lynn NL; Wei, Mei M; Bie, Bihua B; Hershberger, Courtney E CE; Rhoades, Emily E EE; Sen, Alper A; Johnson, Ryan E RE; Steenblik, Jacob J; Hockings, Jennifer J; Budd, G Thomas GT; Eng, Charis C; Foss, Joseph J; Rotroff, Daniel M DM
Publication Date: 2023

Variant appearance in text: rs11572080
PubMed Link: 37251592
Variant Present in the following documents:
  • Main text
  • fpain-04-1139883.pdf
View BVdb publication page



Pharmacogenetic Analysis Enables Optimization of Pain Therapy: A Case Report of Ineffective Oxycodone Therapy.

Journal Of Personalized Medicine
Wiss, Florine M FM; Stäuble, Céline K CK; Meyer Zu Schwabedissen, Henriette E HE; Allemann, Samuel S SS; Lampert, Markus L ML
Publication Date: 2023-05-13

Variant appearance in text: rs11572080
PubMed Link: 37240999
Variant Present in the following documents:
  • jpm-13-00829.pdf
View BVdb publication page



Functional Characterization of Allelic Variations of Human Cytochrome P450 2C8 (V181I, I244V, I331T, and L361F).

International Journal Of Molecular Sciences
Lee, Yoo-Bin YB; Kim, Vitchan V; Lee, Sung-Gyu SG; Lee, Gyu-Hyeong GH; Kim, Changmin C; Jeong, Eunseo E; Kim, Donghak D
Publication Date: 2023-04-28

Variant appearance in text: CYP2C8: R139K
PubMed Link: 37175734
Variant Present in the following documents:
  • Main text
  • ijms-24-08032.pdf
View BVdb publication page



Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.

Nature Communications
Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA
Publication Date: 2023-04-03

Variant appearance in text: CYP2C8: R139K
PubMed Link: 37012232
Variant Present in the following documents:
  • 41467_2023_37547_MOESM12_ESM.xlsx, sheet 2
View BVdb publication page



Circulating messenger RNA variants as a potential biomarker for surveillance of hepatocellular carcinoma.

Frontiers In Oncology
Block, Timothy T; Zezulinski, Daniel D; Kaplan, David E DE; Lu, Jingqiao J; Zanine, Samantha S; Zhan, Tingting T; Doria, Cataldo C; Sayeed, Aejaz A
Publication Date: 2022

Variant appearance in text: rs11572080
PubMed Link: 36582804
Variant Present in the following documents:
  • Table_6.xlsx, sheet 1
View BVdb publication page



Evaluation of Concomitant Use of Anticancer Drugs and Herbal Products: From Interactions to Synergic Activity.

Cancers
Berretta, Massimiliano M; Dal Lago, Lissandra L; Tinazzi, Mattia M; Ronchi, Andrea A; La Rocca, Gaspare G; Montella, Liliana L; Di Francia, Raffaele R; Facchini, Bianca Arianna BA; Bignucolo, Alessia A; Montopoli, Monica M
Publication Date: 2022-10-23

Variant appearance in text: CYP2C8: 416G>A; R139K; rs11572080
PubMed Link: 36358622
Variant Present in the following documents:
  • Main text
  • cancers-14-05203.pdf
View BVdb publication page



Pharmacological counseling in hepatotoxicity induced by macitentan and selexipag:  a case report.

Journal Of Medical Case Reports
Lattanzio, Mariangela M; Ferrari, Marco M; Martini, Stefano S; Ceriani, Francesca F; Imporzani, Andrea A; Marino, Franca F; De Ponti, Roberto R; Cosentino, Marco M
Publication Date: 2022-10-18

Variant appearance in text: CYP2C8: 416G>A; rs11572080
PubMed Link: 36258237
Variant Present in the following documents:
  • Main text
  • 13256_2022_Article_3571.pdf
View BVdb publication page



Association between gene polymorphisms in the cyclophosphamide metabolism pathway with complications after haploidentical hematopoietic stem cell transplantation.

Frontiers In Immunology
Muñiz, Paula P; Andrés-Zayas, Cristina C; Carbonell, Diego D; Chicano, María M; Bailén, Rebeca R; Oarbeascoa, Gillen G; Suárez-González, Julia J; Gómez Centurión, Ignacio I; Dorado, Nieves N; Gallardo, David D; Anguita, Javier J; Kwon, Mi M; Díez-Martín, Jose L JL; Martínez-Laperche, Carolina C; Buño, Ismael I
Publication Date: 2022

Variant appearance in text: rs11572080
PubMed Link: 36211438
Variant Present in the following documents:
  • Table_1.xlsx, sheet 1
View BVdb publication page



The genetic landscape of major drug metabolizing cytochrome P450 genes-an updated analysis of population-scale sequencing data.

The Pharmacogenomics Journal
Zhou, Yitian Y; Lauschke, Volker M VM
Publication Date: 2022-12

Variant appearance in text: CYP2C8: R139K; rs11572080
PubMed Link: 36068297
Variant Present in the following documents:
  • Main text
  • 41397_2022_Article_288.pdf
View BVdb publication page



CYP2C8*3 and *4 define CYP2C8 phenotype: An approach with the substrate cinitapride.

Clinical And Translational Science
Campodónico, Diana María DM; Zubiaur, Pablo P; Soria-Chacartegui, Paula P; Casajús, Ana A; Villapalos-García, Gonzalo G; Navares-Gómez, Marcos M; Gómez-Fernández, Antía A; Parra-Garcés, Raúl R; Mejía-Abril, Gina G; Román, Manuel M; Martín-Vílchez, Samuel S; Ochoa, Dolores D; Abad-Santos, Francisco F
Publication Date: 2022-11

Variant appearance in text: rs11572080
PubMed Link: 36065758
Variant Present in the following documents:
  • Main text
  • CTS-15-2613.pdf
View BVdb publication page



Case Report: Primary Leptomeningeal Medulloblastoma in a Child: Clinical Case Report and Literature Review.

Frontiers In Pediatrics
Morgacheva, Daria D; Daks, Alexandra A; Smirnova, Anna A; Kim, Aleksandr A; Ryzhkova, Daria D; Mitrofanova, Lubov L; Staliarova, Alena A; Omelina, Evgeniya E; Pindyurin, Alexey A; Fedorova, Olga O; Shuvalov, Oleg O; Petukhov, Alexey A; Dinikina, Yulia Y
Publication Date: 2022

Variant appearance in text: CYP2C8: 416G>A; Arg139Lys; rs11572080
PubMed Link: 35899134
Variant Present in the following documents:
  • Table_1.xlsx, sheet 1
View BVdb publication page



Characterization of ADME Gene Variation in Colombian Population by Exome Sequencing.

Frontiers In Pharmacology
Silgado-Guzmán, Daniel Felipe DF; Angulo-Aguado, Mariana M; Morel, Adrien A; Niño-Orrego, María José MJ; Ruiz-Torres, Daniel-Armando DA; Contreras Bravo, Nora Constanza NC; Restrepo, Carlos Martin CM; Ortega-Recalde, Oscar O; Fonseca-Mendoza, Dora Janeth DJ
Publication Date: 2022

Variant appearance in text: CYP2C8: 416G>A; Arg139Lys; rs11572080
PubMed Link: 35846994
Variant Present in the following documents:
  • Table1.xlsx, sheet 1
View BVdb publication page



Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.

Nature Communications
Havugimana, Pierre C PC; Goel, Raghuveera Kumar RK; Phanse, Sadhna S; Youssef, Ahmed A; Padhorny, Dzmitry D; Kotelnikov, Sergei S; Kozakov, Dima D; Emili, Andrew A
Publication Date: 2022-07-13

Variant appearance in text: CYP2C8: 416G>A
PubMed Link: 35831314
Variant Present in the following documents:
  • 41467_2022_31809_MOESM8_ESM.xlsx, sheet 3
View BVdb publication page



The clinically relevant CYP2C8*3 and CYP2C9*2 haplotype is inherited from Neandertals.

The Pharmacogenomics Journal
Haeggström, Sigrid S; Ingelman-Sundberg, Magnus M; Pääbo, Svante S; Zeberg, Hugo H
Publication Date: 2022-07

Variant appearance in text: CYP2C8: R139K; rs11572080
PubMed Link: 35780191
Variant Present in the following documents:
  • Main text
  • 41397_2022_Article_284.pdf
View BVdb publication page



Development of the ADFICE_IT Models for Predicting Falls and Recurrent Falls in Community-Dwelling Older Adults: Pooled Analyses of European Cohorts With Special Attention to Medication.

The Journals Of Gerontology. Series A, Biological Sciences And Medical Sciences
van de Loo, Bob B; Seppala, Lotta J LJ; van der Velde, Nathalie N; Medlock, Stephanie S; Denkinger, Michael M; de Groot, Lisette Cpgm LC; Kenny, Rose-Anne RA; Moriarty, Frank F; Rothenbacher, Dietrich D; Stricker, Bruno B; Uitterlinden, André A; Abu-Hanna, Ameen A; Heymans, Martijn W MW; van Schoor, Natasja N
Publication Date: 2022-07-05

Variant appearance in text: rs11572080
PubMed Link: 35380638
Variant Present in the following documents:
  • glac080_suppl_supplementary_material.pdf
View BVdb publication page



Hornerin deposits in neuronal intranuclear inclusion disease: direct identification of proteins with compositionally biased regions in inclusions.

Acta Neuropathologica Communications
Park, Hongsun H; Yamanaka, Tomoyuki T; Toyama, Yumiko Y; Fujita, Atsushi A; Doi, Hiroshi H; Nirasawa, Takashi T; Murayama, Shigeo S; Matsumoto, Naomichi N; Shimogori, Tomomi T; Ikegawa, Masaya M; Haltia, Matti J MJ; Nukina, Nobuyuki N
Publication Date: 2022-03-04

Variant appearance in text: CYP2C8: Arg139Lys
PubMed Link: 35246273
Variant Present in the following documents:
  • 40478_2022_1333_MOESM3_ESM.xlsx, sheet 2
  • 40478_2022_1333_MOESM3_ESM.xlsx, sheet 1
View BVdb publication page



Multiomics Landscape Uncovers the Molecular Mechanism of the Malignant Evolution of Lung Adenocarcinoma Cells to Chronic Low Dose Cadmium Exposure.

Frontiers In Oncology
Dai, Shun-Dong SD; Wang, Shuang S; Qin, Ya-Nan YN; Zhu, Jin-Chao JC
Publication Date: 2021

Variant appearance in text: CYP2C8: R139K
PubMed Link: 34858801
Variant Present in the following documents:
  • Table_1.xls, sheet 1
View BVdb publication page



Effects of Cytochrome P450 and Transporter Polymorphisms on the Bioavailability and Safety of Dutasteride and Tamsulosin.

Frontiers In Pharmacology
Villapalos-García, Gonzalo G; Zubiaur, Pablo P; Navares-Gómez, Marcos M; Saiz-Rodríguez, Miriam M; Mejía-Abril, Gina G; Martín-Vílchez, Samuel S; Román, Manuel M; Ochoa, Dolores D; Abad-Santos, Francisco F
Publication Date: 2021

Variant appearance in text: rs11572080
PubMed Link: 34690761
Variant Present in the following documents:
  • Main text
  • fphar-12-718281.pdf
View BVdb publication page



Variants in COMT, CYP3A5, CYP2B6, and ABCG2 Alter Quetiapine Pharmacokinetics.

Pharmaceutics
Zubiaur, Pablo P; Fernández-Campos, Paula P; Navares-Gómez, Marcos M; Soria-Chacartegui, Paula P; Villapalos-García, Gonzalo G; Román, Manuel M; Mejía-Abril, Gina G; Ochoa, Dolores D; Abad-Santos, Francisco F
Publication Date: 2021-09-28

Variant appearance in text: rs11572080
PubMed Link: 34683865
Variant Present in the following documents:
  • Main text
View BVdb publication page



Comprehensive analysis of important pharmacogenes in Koreans using the DMET™ platform.

Translational And Clinical Pharmacology
Kim, Byungwook B; Yoon, Deok Yong DY; Lee, SeungHwan S; Jang, In-Jin IJ; Yu, Kyung-Sang KS; Cho, Joo-Youn JY; Oh, Jaeseong J
Publication Date: 2021-09

Variant appearance in text: CYP2C8: R139K; rs11572080
PubMed Link: 34621706
Variant Present in the following documents:
  • Main text
  • tcp-29-135-s001.xls, sheet 1
  • tcp-29-135.pdf
View BVdb publication page



Lack of Major Involvement of Common CYP2C Gene Polymorphisms in the Risk of Developing Cross-Hypersensitivity to NSAIDs.

Frontiers In Pharmacology
Macías, Yolanda Y; García-Menaya, Jesús M JM; Martí, Manuel M; Cordobés, Concepción C; Jurado-Escobar, Raquel R; Cornejo-García, José A JA; Torres, María J MJ; Blanca-López, Natalia N; Canto, Gabriela G; Blanca, Miguel M; Laguna, José J JJ; Bartra, Joan J; Rosado, Ana A; Fernández, Javier J; García-Martín, Elena E; Agúndez, José A G JAG
Publication Date: 2021

Variant appearance in text: rs11572080
PubMed Link: 34621165
Variant Present in the following documents:
  • Main text
View BVdb publication page



PriME-PGx: La Princesa University Hospital Multidisciplinary Initiative for the Implementation of Pharmacogenetics.

Journal Of Clinical Medicine
Zubiaur, Pablo P; Mejía-Abril, Gina G; Navares-Gómez, Marcos M; Villapalos-García, Gonzalo G; Soria-Chacartegui, Paula P; Saiz-Rodríguez, Miriam M; Ochoa, Dolores D; Abad-Santos, Francisco F
Publication Date: 2021-08-24

Variant appearance in text: rs11572080
PubMed Link: 34501219
Variant Present in the following documents:
  • Main text
  • jcm-10-03772.pdf
View BVdb publication page



Population Genetic Difference of Pharmacogenomic VIP Variants in the Tibetan Population.

Pharmacogenomics And Personalized Medicine
He, Chunjuan C; Peng, Linna L; Xing, Shishi S; Li, Dandan D; Wang, Li L; Jin, Tianbo T
Publication Date: 2021

Variant appearance in text: rs11572080
PubMed Link: 34429635
Variant Present in the following documents:
  • Main text
View BVdb publication page



Impact of genetic and non-genetic factors on hepatic CYP2C9 expression and activity in Hungarian subjects.

Scientific Reports
Fekete, Ferenc F; Mangó, Katalin K; Déri, Máté M; Incze, Evelyn E; Minus, Annamária A; Monostory, Katalin K
Publication Date: 2021-08-24

Variant appearance in text: rs11572080
PubMed Link: 34429480
Variant Present in the following documents:
  • Main text
  • 41598_2021_Article_96590.pdf
View BVdb publication page



A pilot study of oral treprostinil pharmacogenomics and treatment persistence in patients with pulmonary arterial hypertension.

Therapeutic Advances In Respiratory Disease
Coons, James C JC; Crisamore, Karryn K; Adams, Solomon S; Modany, Ashley A; Simon, Marc A MA; Zhao, Wenchen W; Shaik, Imam H IH; Venkataramanan, Raman R; Empey, Philip E PE
Publication Date: 2021

Variant appearance in text: rs11572080
PubMed Link: 33929912
Variant Present in the following documents:
  • Main text
View BVdb publication page



Hypertension in African Populations: Review and Computational Insights.

Genes
Mabhida, Sihle E SE; Mashatola, Lebohang L; Kaur, Mandeep M; Sharma, Jyoti R JR; Apalata, Teke T; Muhamed, Babu B; Benjeddou, Mongi M; Johnson, Rabia R
Publication Date: 2021-04-06

Variant appearance in text: rs11572080
PubMed Link: 33917487
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic variants related to successful migraine prophylaxis with verapamil.

Molecular Genetics & Genomic Medicine
Cutrer, Fred Michael FM; Moyer, Ann M AM; Atkinson, Elizabeth J EJ; Wang, Liguo L; Tian, Shulan S; Wu, Yanhong Y; Garza, Ivan I; Robertson, Carrie E CE; Huebert, Carey A CA; Moore, Brenda E BE; Klein, Christopher J CJ
Publication Date: 2021-06

Variant appearance in text: rs11572080
PubMed Link: 33829662
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic variants related to successful migraine prophylaxis with verapamil.

Molecular Genetics & Genomic Medicine
Cutrer, Fred Michael FM; Moyer, Ann M AM; Atkinson, Elizabeth J EJ; Wang, Liguo L; Tian, Shulan S; Wu, Yanhong Y; Garza, Ivan I; Robertson, Carrie E CE; Huebert, Carey A CA; Moore, Brenda E BE; Klein, Christopher J CJ
Publication Date: 2021-06

Variant appearance in text: rs11572080
PubMed Link: 33829662
Variant Present in the following documents:
  • Main text
View BVdb publication page



SLCO1B1 Phenotype and CYP3A5 Polymorphism Significantly Affect Atorvastatin Bioavailability.

Journal Of Personalized Medicine
Zubiaur, Pablo P; Benedicto, Maria Dolores MD; Villapalos-García, Gonzalo G; Navares-Gómez, Marcos M; Mejía-Abril, Gina G; Román, Manuel M; Martín-Vílchez, Samuel S; Ochoa, Dolores D; Abad-Santos, Francisco F
Publication Date: 2021-03-13

Variant appearance in text: rs11572080
PubMed Link: 33805706
Variant Present in the following documents:
  • Main text
View BVdb publication page



Generating a Precision Endoxifen Prediction Algorithm to Advance Personalized Tamoxifen Treatment in Patients with Breast Cancer.

Journal Of Personalized Medicine
Helland, Thomas T; Alsomairy, Sarah S; Lin, Chenchia C; Søiland, Håvard H; Mellgren, Gunnar G; Hertz, Daniel Louis DL
Publication Date: 2021-03-13

Variant appearance in text: rs11572080
PubMed Link: 33805613
Variant Present in the following documents:
  • Main text
View BVdb publication page



Pharmacogenetics of Carbamazepine and Valproate: Focus on Polymorphisms of Drug Metabolizing Enzymes and Transporters.

Pharmaceuticals (Basel, Switzerland)
Iannaccone, Teresa T; Sellitto, Carmine C; Manzo, Valentina V; Colucci, Francesca F; Giudice, Valentina V; Stefanelli, Berenice B; Iuliano, Antonio A; Corrivetti, Giulio G; Filippelli, Amelia A
Publication Date: 2021-03-01

Variant appearance in text: rs11572080
PubMed Link: 33804537
Variant Present in the following documents:
  • Main text
  • pharmaceuticals-14-00204.pdf
View BVdb publication page



Genetic Predictors of Chemotherapy-Induced Peripheral Neuropathy from Paclitaxel, Carboplatin and Oxaliplatin: NCCTG/Alliance N08C1, N08CA and N08CB Study.

Cancers
Adjei, Araba A AA; Lopez, Camden L CL; Schaid, Daniel J DJ; Sloan, Jeff A JA; Le-Rademacher, Jennifer G JG; Loprinzi, Charles L CL; Norman, Aaron D AD; Olson, Janet E JE; Couch, Fergus J FJ; Beutler, Andreas S AS; Vachon, Celine M CM; Ruddy, Kathryn J KJ
Publication Date: 2021-03-03

Variant appearance in text: rs11572080
PubMed Link: 33802509
Variant Present in the following documents:
  • Main text
View BVdb publication page



Whole-Exome Sequencing in Patients Affected by Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Reveals New Variants Potentially Contributing to the Phenotype.

Pharmacogenomics And Personalized Medicine
Fonseca, Dora Janeth DJ; Morel, Adrien A; Llinás-Caballero, Kevin K; Bolívar-Salazar, David D; Laissue, Paul P
Publication Date: 2021

Variant appearance in text: CYP2C8: 416G>A; Arg139Lys; rs11572080
PubMed Link: 33688237
Variant Present in the following documents:
  • Main text
  • pgpm-14-287.pdf
View BVdb publication page



Metabolism pathways of arachidonic acids: mechanisms and potential therapeutic targets.

Signal Transduction And Targeted Therapy
Wang, Bei B; Wu, Lujin L; Chen, Jing J; Dong, Lingli L; Chen, Chen C; Wen, Zheng Z; Hu, Jiong J; Fleming, Ingrid I; Wang, Dao Wen DW
Publication Date: 2021-02-26

Variant appearance in text: CYP2C8: Arg139Lys; rs11572080
PubMed Link: 33637672
Variant Present in the following documents:
  • Main text
View BVdb publication page



Influence of cytochrome P450 (CYP) 2C8 polymorphisms on the efficacy and tolerability of artesunate-amodiaquine treatment of uncomplicated Plasmodium falciparum malaria in Zanzibar.

Malaria Journal
Pernaute-Lau, Leyre L; Morris, Ulrika U; Msellem, Mwinyi M; Mårtensson, Andreas A; Björkman, Anders A; Gil, Jose Pedro JP
Publication Date: 2021-02-15

Variant appearance in text: CYP2C8: R139K
PubMed Link: 33588856
Variant Present in the following documents:
  • Main text
  • 12936_2021_Article_3620.pdf
View BVdb publication page



Preservation of epoxyeicosatrienoic acid bioavailability prevents renal allograft dysfunction and cardiovascular alterations in kidney transplant recipients.

Scientific Reports
Duflot, Thomas T; Laurent, Charlotte C; Soudey, Anne A; Fonrose, Xavier X; Hamzaoui, Mouad M; Iacob, Michèle M; Bertrand, Dominique D; Favre, Julie J; Etienne, Isabelle I; Roche, Clothilde C; Coquerel, David D; Le Besnerais, Maëlle M; Louhichi, Safa S; Tarlet, Tracy T; Li, Dongyang D; Brunel, Valéry V; Morisseau, Christophe C; Richard, Vincent V; Joannidès, Robinson R; Stanke-Labesque, Françoise F; Lamoureux, Fabien F; Guerrot, Dominique D; Bellien, Jérémy J
Publication Date: 2021-02-12

Variant appearance in text: rs11572080
PubMed Link: 33580125
Variant Present in the following documents:
  • Main text
View BVdb publication page



Gene-environment interactions between air pollution and biotransformation enzymes and risk of birth defects.

Birth Defects Research
Padula, Amy M AM; Yang, Wei W; Schultz, Kathleen K; Lee, Cecilia C; Lurmann, Fred F; Hammond, S Katharine SK; Shaw, Gary M GM
Publication Date: 2021-05-15

Variant appearance in text: rs11572080
PubMed Link: 33569925
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic Diversity of Drug-Related Genes in Native Americans of the Brazilian Amazon.

Pharmacogenomics And Personalized Medicine
Fernandes, Marianne Rodrigues MR; Rodrigues, Juliana Carla Gomes JCG; Maroñas, Olalla O; Latorre-Pellicer, Ana A; Cruz, Raquel R; Guerreiro, João Farias JF; Burbano, Rommel Mario Rodriguez RMR; de Assumpção, Paulo Pimentel PP; Ribeiro-Dos-Santos, Andrea A; Dos Santos, Sidney Emanuel Batista SEB; Carracedo, Angel A; Dos Santos, Ney Pereira Carneiro NPC
Publication Date: 2021

Variant appearance in text: rs11572080
PubMed Link: 33519226
Variant Present in the following documents:
  • Main text
  • pgpm-14-117.pdf
View BVdb publication page



Decoding variants in drug-metabolizing enzymes and transporters in solid tumor patients by whole-exome sequencing.

Saudi Journal Of Biological Sciences
Aboul-Soud, Mourad A M MAM; Alzahrani, Alhussain J AJ; Mahmoud, Amer A
Publication Date: 2021-01

Variant appearance in text: rs11572080
PubMed Link: 33424349
Variant Present in the following documents:
  • mmc1.xlsx, sheet 1
View BVdb publication page



Variation in 100 relevant pharmacogenes among emiratis with insights from understudied populations.

Scientific Reports
Al-Mahayri, Zeina N ZN; Patrinos, George P GP; Wattanapokayakit, Sukanya S; Iemwimangsa, Nareenart N; Fukunaga, Koya K; Mushiroda, Taisei T; Chantratita, Wasun W; Ali, Bassam R BR
Publication Date: 2020-12-04

Variant appearance in text: rs11572080
PubMed Link: 33277594
Variant Present in the following documents:
  • 41598_2020_78231_MOESM1_ESM.pdf
View BVdb publication page



VEGF-Related Germinal Polymorphisms May Identify a Subgroup of Breast Cancer Patients with Favorable Outcome under Bevacizumab-Based Therapy-A Message from COMET, a French Unicancer Multicentric Study.

Pharmaceuticals (Basel, Switzerland)
Gal, Jocelyn J; Milano, Gérard G; Brest, Patrick P; Ebran, Nathalie N; Gilhodes, Julia J; Llorca, Laurence L; Dubot, Coraline C; Romieu, Gilles G; Desmoulins, Isabelle I; Brain, Etienne E; Goncalves, Anthony A; Ferrero, Jean-Marc JM; Cottu, Paul-Henri PH; Debled, Marc M; Tredan, Olivier O; Chamorey, Emmanuel E; Merlano, Marco Carlo MC; Lemonnier, Jérôme J; Etienne-Grimaldi, Marie-Christine MC; Pierga, Jean-Yves JY
Publication Date: 2020-11-23

Variant appearance in text: rs11572080
PubMed Link: 33238394
Variant Present in the following documents:
  • Main text
View BVdb publication page



Evaluation of clinical and genetic factors in the population pharmacokinetics of carbamazepine.

British Journal Of Clinical Pharmacology
Yip, Vincent L M VLM; Pertinez, Henry H; Meng, Xiaoli X; Maggs, James L JL; Carr, Daniel F DF; Park, B Kevin BK; Marson, Anthony G AG; Pirmohamed, Munir M
Publication Date: 2021-06

Variant appearance in text: rs11572080
PubMed Link: 33217013
Variant Present in the following documents:
  • Main text
View BVdb publication page



Prevalence of CYP2C8*2 and *3 among Eritreans and its Potential Impact on Artesunate/Amodiaquine Treatment.

Pharmacogenomics And Personalized Medicine
Habtemikael, Lidia L; Russom, Mulugeta M; Bahta, Iyassu I; Mihreteab, Selam S; Berhane, Araia A; Mårtensson, Andreas A; Gil, Jose Pedro JP
Publication Date: 2020

Variant appearance in text: CYP2C8: R139K
PubMed Link: 33209048
Variant Present in the following documents:
  • Main text
  • pgpm-13-571.pdf
View BVdb publication page



Pharmacogenetics of Type 2 Diabetes-Progress and Prospects.

International Journal Of Molecular Sciences
Nasykhova, Yulia A YA; Tonyan, Ziravard N ZN; Mikhailova, Anastasiia A AA; Danilova, Maria M MM; Glotov, Andrey S AS
Publication Date: 2020-09-18

Variant appearance in text: CYP2C8: Arg139Lys; rs11572080
PubMed Link: 32961860
Variant Present in the following documents:
  • Main text
  • ijms-21-06842.pdf
View BVdb publication page



Development and Analytical Validation of a 29 Gene Clinical Pharmacogenetic Genotyping Panel: Multi-Ethnic Allele and Copy Number Variant Detection.

Clinical And Translational Science
Scott, Stuart A SA; Scott, Erick R ER; Seki, Yoshinori Y; Chen, Annette J AJ; Wallsten, Richard R; Owusu Obeng, Aniwaa A; Botton, Mariana R MR; Cody, Neal N; Shi, Huanzhi H; Zhao, Geping G; Brake, Paul P; Nicoletti, Paola P; Yang, Yao Y; Delio, Maria M; Shi, Lisong L; Kornreich, Ruth R; Schadt, Eric E EE; Edelmann, Lisa L
Publication Date: 2021-01

Variant appearance in text: CYP2C8: Arg139Lys; rs11572080
PubMed Link: 32931151
Variant Present in the following documents:
  • CTS-14-204-s001.xlsx, sheet 1
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Population Pharmacokinetic and Pharmacogenetic Analysis of Mitotane in Patients with Adrenocortical Carcinoma: Towards Individualized Dosing.

Clinical Pharmacokinetics
Yin, Anyue A; Ettaieb, Madeleine H T MHT; Swen, Jesse J JJ; van Deun, Liselotte L; Kerkhofs, Thomas M A TMA; van der Straaten, Robert J H M RJHM; Corssmit, Eleonora P M EPM; Gelderblom, Hans H; Kerstens, Michiel N MN; Feelders, Richard A RA; Eekhoff, Marelise M; Timmers, Henri J L M HJLM; D'Avolio, Antonio A; Cusato, Jessica J; Guchelaar, Henk-Jan HJ; Haak, Harm R HR; Moes, Dirk Jan A R DJAR
Publication Date: 2021-01

Variant appearance in text: CYP2C8: R139K; rs11572080
PubMed Link: 32607875
Variant Present in the following documents:
  • 40262_2020_913_MOESM3_ESM.xlsx, sheet 1
View BVdb publication page



Unique insights from ClinicalTrials.gov by mining protein mutations and RSids in addition to applying the Human Phenotype Ontology.

Plos One
Alag, Shray S
Publication Date: 2020

Variant appearance in text: rs11572080
PubMed Link: 32459809
Variant Present in the following documents:
  • Main text
  • pone.0233438.pdf
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Influence of CYP2C8, CYP3A4, and CYP3A5 Host Genotypes on Early Recurrence of Plasmodium vivax.

Antimicrobial Agents And Chemotherapy
Almeida, Anne C G ACG; Puça, Maria C B MCB; Figueiredo, Erick F G EFG; Barbosa, Laila R LR; Salazar, Yanka E A R YEAR; Silva, Emanuelle L EL; Brito, Marcelo A M MAM; Siqueira, André M AM; Vieira, José L F JLF; Lacerda, Marcus V G MVG; Monteiro, Wuelton M WM; Melo, Gisely C GC
Publication Date: 2020-06-23

Variant appearance in text: rs11572080
PubMed Link: 32366712
Variant Present in the following documents:
  • Main text
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Importance of genetic polymorphisms in liver transplantation outcomes.

World Journal Of Gastroenterology
Kelava, Tomislav T; Turcic, Petra P; Markotic, Antonio A; Ostojic, Ana A; Sisl, Dino D; Mrzljak, Anna A
Publication Date: 2020-03-28

Variant appearance in text: rs11572080
PubMed Link: 32256016
Variant Present in the following documents:
  • Main text
  • WJG-26-1273.pdf
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Pharmacogenomic network analysis of the gene-drug interaction landscape underlying drug disposition.

Computational And Structural Biotechnology Journal
Zhou, Yitian Y; Lauschke, Volker M VM
Publication Date: 2020

Variant appearance in text: rs11572080
PubMed Link: 31890144
Variant Present in the following documents:
  • main.pdf
View BVdb publication page