ATM c.982_983delinsGC ;(p.S328A)

Variant ID: 11-108117771-AG-GC

NM_000051.3(ATM):c.982_983delinsGC;(p.S328A)

This variant was identified in 8 publications

View GRCh38 version.




Publications:


MRN, CtIP, and BRCA1 mediate repair of topoisomerase II-DNA adducts.

The Journal Of Cell Biology
Aparicio, Tomas T; Baer, Richard R; Gottesman, Max M; Gautier, Jean J
Publication Date: 2016-02-15

Variant appearance in text: ATM: S328A
PubMed Link: 26880199
Variant Present in the following documents:
  • Main text
  • JCB_201504005.pdf
View BVdb publication page



Tousled-like kinase-dependent phosphorylation of Rad9 plays a role in cell cycle progression and G2/M checkpoint exit.

Plos One
Kelly, Ryan R; Davey, Scott K SK
Publication Date: 2013

Variant appearance in text: ATM: S328A
PubMed Link: 24376897
Variant Present in the following documents:
  • Main text
  • pone.0085859.pdf
View BVdb publication page



Phenothiazine Inhibitors of TLKs Affect Double-Strand Break Repair and DNA Damage Response Recovery and Potentiate Tumor Killing with Radiomimetic Therapy.

Genes & Cancer
Ronald, Sharon S; Awate, Sanket S; Rath, Abhijit A; Carroll, Jennifer J; Galiano, Floyd F; Dwyer, Donard D; Kleiner-Hancock, Heather H; Mathis, J Michael JM; Vigod, Simone S; De Benedetti, Arrigo A
Publication Date: 2013-01

Variant appearance in text: ATM: S328A
PubMed Link: 23946870
Variant Present in the following documents:
  • Main text
View BVdb publication page



The MRN-CtIP pathway is required for metaphase chromosome alignment.

Molecular Cell
Rozier, Lorene L; Guo, Yige Y; Peterson, Shaun S; Sato, Mai M; Baer, Richard R; Gautier, Jean J; Mao, Yinghui Y
Publication Date: 2013-03-28

Variant appearance in text: ATM: S328A
PubMed Link: 23434370
Variant Present in the following documents:
  • Main text
View BVdb publication page



Phosphorylation of Rad9 at serine 328 by cyclin A-Cdk2 triggers apoptosis via interfering Bcl-xL.

Plos One
Zhan, Zhuo Z; He, Kan K; Zhu, Dan D; Jiang, Dan D; Huang, Ying-Hui YH; Li, Yang Y; Sun, Chao C; Jin, Ying-Hua YH
Publication Date: 2012

Variant appearance in text: ATM: S328A
PubMed Link: 23028682
Variant Present in the following documents:
  • Main text
  • pone.0044923.pdf
View BVdb publication page



A role for the arginine methylation of Rad9 in checkpoint control and cellular sensitivity to DNA damage.

Nucleic Acids Research
He, Wei W; Ma, Xiaoyan X; Yang, Xiao X; Zhao, Yun Y; Qiu, Junkang J; Hang, Haiying H
Publication Date: 2011-06

Variant appearance in text: ATM: Ser328Ala
PubMed Link: 21321020
Variant Present in the following documents:
  • Main text
  • gkq1264.pdf
View BVdb publication page



Rad9A is required for G2 decatenation checkpoint and to prevent endoreduplication in response to topoisomerase II inhibition.

The Journal Of Biological Chemistry
Greer Card, Deborah A DA; Sierant, Megan L ML; Davey, Scott S
Publication Date: 2010-05-14

Variant appearance in text: ATM: S328A
PubMed Link: 20305300
Variant Present in the following documents:
  • Main text
View BVdb publication page



TLK1B promotes repair of DSBs via its interaction with Rad9 and Asf1.

Bmc Molecular Biology
Canfield, Caroline C; Rains, Justin J; De Benedetti, Arrigo A
Publication Date: 2009-12-20

Variant appearance in text: ATM: S328A
PubMed Link: 20021694
Variant Present in the following documents:
  • Main text
  • 1471-2199-10-110.pdf
View BVdb publication page