Genomic characterization of high-count MBL cases indicates that early detection of driver mutations and subclonal expansion are predictors of adverse clinical outcome.
Leukemia
Barrio, S S; Shanafelt, T D TD; Ojha, J J; Chaffee, K G KG; Secreto, C C; Kortüm, K M KM; Pathangey, S S; Van-Dyke, D L DL; Slager, S L SL; Fonseca, R R; Kay, N E NE; Braggio, E E
Monoclonal B-cell lymphocytosis is characterized by mutations in CLL putative driver genes and clonal heterogeneity many years before disease progression.
Leukemia
Ojha, J J; Secreto, C C; Rabe, K K; Ayres-Silva, J J; Tschumper, R R; Dyke, D V DV; Slager, S S; Fonseca, R R; Shanafelt, T T; Kay, N N; Braggio, E E