Publications:

---

Allele-specific enhancers mediate associations between LCAT and ABCA1 polymorphisms and HDL metabolism.

Plos One

AD Howard, X Wang, M Prasad, AD Sahu, R Aniba, M Miller, S Hannenhalli, YC Chang

Publication Date: 2019

Variant appearance in text: rs12286037

PubMed Link: 31039173

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Frequency and phenotype consequence of APOC3 rare variants in patients with very low triglyceride levels.

Bmc Medical Genomics

DC Crawford, NA Restrepo, KE Diggins, E Farber-Eger, QS Wells

Publication Date: 2018-09-14

Variant appearance in text: rs12286037

PubMed Link: 30255797

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study.

Plos Genetics

JP Davis, JR Huyghe, AE Locke, AU Jackson, X Sim, HM Stringham, TM Teslovich, RP Welch, C Fuchsberger, N Narisu, PS Chines, AJ Kangas, P Soininen, M Ala-Korpela, J Kuusisto, FS Collins, M Laakso, M Boehnke, KL Mohlke

Publication Date: 2017-10

Variant appearance in text: rs12286037

PubMed Link: 29084231

Variant Present in the following documents:

• pgen.1007079.s010.xlsx

View BVdb publication page

---

Transforming growth factor-β signaling pathway-associated genes SMAD2 and TGFBR2 are implicated in metabolic syndrome in a Taiwanese population.

Scientific Reports

E Lin, PH Kuo, YL Liu, AC Yang, SJ Tsai

Publication Date: 2017-10-19

Variant appearance in text: rs12286037

PubMed Link: 29051557

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers.

Plos One

LC Pilling, JL Atkins, MO Duff, RN Beaumont, SE Jones, J Tyrrell, CL Kuo, KS Ruth, MA Tuke, H Yaghootkar, AR Wood, A Murray, MN Weedon, LW Harries, GA Kuchel, L Ferrucci, TM Frayling, D Melzer

Publication Date: 2017

Variant appearance in text: rs12286037

PubMed Link: 28957414

Variant Present in the following documents:

• pone.0185083.s004.xlsx

View BVdb publication page

---

Pharmacogenetic meta-analysis of baseline risk factors, pharmacodynamic, efficacy and tolerability endpoints from two large global cardiovascular outcomes trials for darapladib.

Plos One

A Yeo, L Li, L Warren, J Aponte, D Fraser, K King, K Johansson, A Barnes, C MacPhee, R Davies, S Chissoe, E Tarka, ML O'Donoghue, HD White, L Wallentin, D Waterworth

Publication Date: 2017

Variant appearance in text: rs12286037

PubMed Link: 28753643

Variant Present in the following documents:

• pone.0182115.s015.xlsx
• pone.0182115.s016.xlsx

View BVdb publication page

---

Association of BUD13 polymorphisms with metabolic syndrome in Chinese population: a case-control study.

Lipids In Health And Disease

L Zhang, Y You, Y Wu, Y Zhang, M Wang, Y Song, X Liu, C Kou

Publication Date: 2017-06-28

Variant appearance in text: rs12286037

PubMed Link: 28659142

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Whole genome sequencing and imputation in isolated populations identify genetic associations with medically-relevant complex traits.

Nature Communications

L Southam, A Gilly, D Süveges, AE Farmaki, J Schwartzentruber, I Tachmazidou, A Matchan, NW Rayner, E Tsafantakis, M Karaleftheri, Y Xue, G Dedoussis, E Zeggini

Publication Date: 2017-05-26

Variant appearance in text: rs12286037

PubMed Link: 28548082

Variant Present in the following documents:

• ncomms15606-s1.pdf

View BVdb publication page

---

Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci.

Human Molecular Genetics

N Zubair, M Graff, J Luis Ambite, WS Bush, G Kichaev, Y Lu, A Manichaikul, WH Sheu, D Absher, TL Assimes, SJ Bielinski, EP Bottinger, P Buzkova, LM Chuang, RH Chung, B Cochran, L Dumitrescu, O Gottesman, JW Haessler, C Haiman, G Heiss, CA Hsiung, YJ Hung, CM Hwu, JJ Juang, L Le Marchand, IT Lee, WJ Lee, LA Lin, D Lin, SY Lin, RH Mackey, LW Martin, B Pasaniuc, U Peters, I Predazzi, T Quertermous, AP Reiner, J Robinson, JI Rotter, KK Ryckman, PJ Schreiner, E Stahl, R Tao, MY Tsai, LL Waite, TD Wang, S Buyske, YD Ida Chen, I Cheng, DC Crawford, RJF Loos, SS Rich, M Fornage, KE North, C Kooperberg, CL Carty

Publication Date: 2016-12-15

Variant appearance in text: rs12286037

PubMed Link: 28426890

Variant Present in the following documents:

• Main text
• ddw358_supp.docx

View BVdb publication page

---

Two-stage association study to identify the genetic susceptibility of a novel common variant of rs2075290 in ZPR1 to type 2 diabetes.

Scientific Reports

F Guan, Y Niu, T Zhang, S Liu, L Ma, T Qi, J Feng, H Zuo, G Li, X Liu, S Wang

Publication Date: 2016-07-14

Variant appearance in text: rs12286037

PubMed Link: 27411854

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Distinct Patterns of Association of Variants at 11q23.3 Chromosomal Region with Coronary Artery Disease and Dyslipidemia in the Population of Andhra Pradesh, India.

Plos One

R Pranav Chand, AS Kumar, K Anuj, S Vishnupriya, B Mohan Reddy

Publication Date: 2016

Variant appearance in text: rs12286037

PubMed Link: 27257688

Variant Present in the following documents:

• Main text
• pone.0153720.s002.docx
• pone.0153720.s003.xlsx

View BVdb publication page

---

Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.

Scientific Reports

JE Below, EJ Parra, ER Gamazon, J Torres, S Krithika, S Candille, Y Lu, A Manichakul, J Peralta-Romero, Q Duan, Y Li, AP Morris, O Gottesman, E Bottinger, XQ Wang, KD Taylor, YD Ida Chen, JI Rotter, SS Rich, RJ Loos, H Tang, NJ Cox, M Cruz, CL Hanis, A Valladares-Salgado

Publication Date: 2016-01-19

Variant appearance in text: rs12286037

PubMed Link: 26780889

Variant Present in the following documents:

• srep19429-s3.xls

View BVdb publication page

---

INTEGRATING CLINICAL LABORATORY MEASURES AND ICD-9 CODE DIAGNOSES IN PHENOME-WIDE ASSOCIATION STUDIES.

Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing

A Verma, JB Leader, SS Verma, A Frase, J Wallace, S Dudek, DR Lavage, CV Van Hout, FE Dewey, J Penn, A Lopez, JD Overton, DJ Carey, DH Ledbetter, HL Kirchner, MD Ritchie, SA Pendergrass

Publication Date: 2016

Variant appearance in text: rs12286037

PubMed Link: 26776183

Variant Present in the following documents:

• NIHMS742521-supplement-2.pdf

View BVdb publication page

---

The interaction of Apolipoprotein A5 gene promoter region T-1131C polymorphism (rs12286037) and lifestyle modification on plasma triglyceride levels in Japanese.

Nutrition Research And Practice

M Yamasaki, PB Mutombo, M Iwamoto, A Nogi, M Hashimoto, T Nabika, K Shiwaku

Publication Date: 2015-08

Variant appearance in text: rs12286037

PubMed Link: 26244076

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Evaluation of transethnic fine mapping with population-specific and cosmopolitan imputation reference panels in diverse Asian populations.

European Journal Of Human Genetics : Ejhg

X Wang, CY Cheng, J Liao, X Sim, J Liu, KS Chia, ES Tai, P Little, CC Khor, T Aung, TY Wong, YY Teo

Publication Date: 2016-04

Variant appearance in text: rs12286037

PubMed Link: 26130488

Variant Present in the following documents:

• ejhg2015150x4.xls

View BVdb publication page

---

Apolipoprotein E and protection against hepatitis E viral infection in American non-Hispanic blacks.

Hepatology (Baltimore, Md.)

L Zhang, A Yesupriya, MH Chang, E Teshale, CG Teo

Publication Date: 2015-11

Variant appearance in text: rs12286037

PubMed Link: 26096528

Variant Present in the following documents:

• NIHMS1043972-supplement-Supplemental.pdf

View BVdb publication page

---

Lipids, obesity and gallbladder disease in women: insights from genetic studies using the cardiovascular gene-centric 50K SNP array.

European Journal Of Human Genetics : Ejhg

S Rodriguez, TR Gaunt, Y Guo, J Zheng, MR Barnes, W Tang, F Danish, A Johnson, BA Castillo, YR Li, H Hakonarson, SG Buxbaum, T Palmer, MY Tsai, LA Lange, S Ebrahim, G Davey Smith, DA Lawlor, AR Folsom, R Hoogeveen, A Reiner, B Keating, IN Day

Publication Date: 2016-01

Variant appearance in text: rs12286037

PubMed Link: 25920552

Variant Present in the following documents:

• ejhg201563x1.doc

View BVdb publication page

---

Burden of disease variants in participants of the Long Life Family Study.

Aging

M Stevenson, H Bae, N Schupf, S Andersen, Q Zhang, T Perls, P Sebastiani

Publication Date: 2015-02

Variant appearance in text: rs12286037

PubMed Link: 25664523

Variant Present in the following documents:

• aging-07-0123-s001.docx

View BVdb publication page

---

Detection of pleiotropy through a Phenome-wide association study (PheWAS) of epidemiologic data as part of the Environmental Architecture for Genes Linked to Environment (EAGLE) study.

Plos Genetics

MA Hall, A Verma, KD Brown-Gentry, R Goodloe, J Boston, S Wilson, B McClellan, C Sutcliffe, HH Dilks, NB Gillani, H Jin, P Mayo, M Allen, N Schnetz-Boutaud, DC Crawford, MD Ritchie, SA Pendergrass

Publication Date: 2014-12

Variant appearance in text: rs12286037

PubMed Link: 25474351

Variant Present in the following documents:

• pgen.1004678.s007.xlsx
• pgen.1004678.s008.xlsx
• pgen.1004678.s009.xlsx
• pgen.1004678.s011.xlsx

View BVdb publication page

---

Rare variant APOC3 R19X is associated with cardio-protective profiles in a diverse population-based survey as part of the Epidemiologic Architecture for Genes Linked to Environment Study.

Circulation. Cardiovascular Genetics

DC Crawford, L Dumitrescu, R Goodloe, K Brown-Gentry, J Boston, B McClellan, C Sutcliffe, R Wiseman, P Baker, MA Pericak-Vance, WK Scott, M Allen, P Mayo, N Schnetz-Boutaud, HH Dilks, JL Haines, TI Pollin

Publication Date: 2014-12

Variant appearance in text: rs12286037

PubMed Link: 25363704

Variant Present in the following documents:

• NIHMS640711-supplement-000369_-_Supplemental_Material.pdf

View BVdb publication page

---

Multiancestral analysis of inflammation-related genetic variants and C-reactive protein in the population architecture using genomics and epidemiology study.

Circulation. Cardiovascular Genetics

JM Kocarnik, SA Pendergrass, CL Carty, JS Pankow, FR Schumacher, I Cheng, P Durda, JL Ambite, E Deelman, NR Cook, S Liu, J Wactawski-Wende, C Hutter, K Brown-Gentry, S Wilson, LG Best, N Pankratz, CP Hong, SA Cole, VS Voruganti, P Bůžkova, NW Jorgensen, NS Jenny, LR Wilkens, CA Haiman, LN Kolonel, A Lacroix, K North, R Jackson, L Le Marchand, LA Hindorff, DC Crawford, M Gross, U Peters

Publication Date: 2014-04

Variant appearance in text: rs12286037

PubMed Link: 24622110

Variant Present in the following documents:

• NIHMS575195-supplement-000173_-_Supplemental_Material.pdf

View BVdb publication page

---

Biobanking across the phenome - at the center of chronic disease research.

Bmc Public Health

M Imboden, NM Probst-Hensch

Publication Date: 2013-11-25

Variant appearance in text: rs12286037

PubMed Link: 24274136

Variant Present in the following documents:

• 1471-2458-13-1094-S2.xlsx

View BVdb publication page

---

Lipid trait-associated genetic variation is associated with gallstone disease in the diverse Third National Health and Nutrition Examination Survey (NHANES III).

Bmc Medical Genetics

R Goodloe, K Brown-Gentry, NB Gillani, H Jin, P Mayo, M Allen, B McClellan, J Boston, C Sutcliffe, N Schnetz-Boutaud, HH Dilks, DC Crawford

Publication Date: 2013-11-21

Variant appearance in text: rs12286037

PubMed Link: 24256507

Variant Present in the following documents:

• 1471-2350-14-120-S1.doc

View BVdb publication page

---

Gene-centric association signals for haemostasis and thrombosis traits identified with the HumanCVD BeadChip.

Thrombosis And Haemostasis

TR Gaunt, D Zabaneh, S Shah, A Guyatt, C Ladroue, M Kumari, F Drenos, T Shah, PJ Talmud, JP Casas, G Lowe, A Rumley, DA Lawlor, M Kivimaki, J Whittaker, AD Hingorani, SE Humphries, IN Day

Publication Date: 2013-11

Variant appearance in text: rs12286037

PubMed Link: 24178511

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Genetic susceptibility for ischemic infarction and arteriolosclerosis based on neuropathologic evaluations.

Cerebrovascular Diseases (Basel, Switzerland)

SY Chou, JM Shulman, BT Keenan, EA Secor, AS Buchman, J Schneider, DA Bennett, PL De Jager

Publication Date: 2013

Variant appearance in text: rs12286037

PubMed Link: 24135527

Variant Present in the following documents:

• NIHMS527173-supplement-01.pdf

View BVdb publication page

---

Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels.

Journal Of Lipid Research

Y Wu, AF Marvelle, J Li, DC Croteau-Chonka, AB Feranil, CW Kuzawa, Y Li, LS Adair, KL Mohlke

Publication Date: 2013-11

Variant appearance in text: rs12286037

PubMed Link: 24023260

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Properties of local interactions and their potential value in complementing genome-wide association studies.

Plos One

W Wei, A Gyenesei, CA Semple, CS Haley

Publication Date: 2013

Variant appearance in text: rs12286037

PubMed Link: 23940718

Variant Present in the following documents:

• pone.0071203.s003.xlsx

View BVdb publication page

---

Do genetic modifiers of high-density lipoprotein cholesterol and triglyceride levels also modify their response to a lifestyle intervention in the setting of obesity and type-2 diabetes mellitus?: The Action for Health in Diabetes (Look AHEAD) study.

Circulation. Cardiovascular Genetics

GS Huggins, GD Papandonatos, B Erar, LM Belalcazar, A Brautbar, C Ballantyne, AE Kitabchi, LE Wagenknecht, WC Knowler, HJ Pownall, RR Wing, I Peter, JM McCaffery,

Publication Date: 2013-08

Variant appearance in text: rs12286037

PubMed Link: 23861364

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Genetic variants from lipid-related pathways and risk for incident myocardial infarction.

Plos One

C Song, NL Pedersen, CA Reynolds, M Sabater-Lleal, S Kanoni, C Willenborg, , AC Syvänen, H Watkins, A Hamsten, JA Prince, E Ingelsson

Publication Date: 2013

Variant appearance in text: rs12286037

PubMed Link: 23555974

Variant Present in the following documents:

• pone.0060454.s001.pdf

View BVdb publication page

---

Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained.

Plos Genetics

Y Wu, LL Waite, AU Jackson, WH Sheu, S Buyske, D Absher, DK Arnett, E Boerwinkle, LL Bonnycastle, CL Carty, I Cheng, B Cochran, DC Croteau-Chonka, L Dumitrescu, CB Eaton, N Franceschini, X Guo, BE Henderson, LA Hindorff, E Kim, L Kinnunen, P Komulainen, WJ Lee, L Le Marchand, Y Lin, J Lindström, O Lingaas-Holmen, SL Mitchell, N Narisu, JG Robinson, F Schumacher, A Stančáková, J Sundvall, YJ Sung, AJ Swift, WC Wang, L Wilkens, T Wilsgaard, AM Young, LS Adair, CM Ballantyne, P Bůžková, A Chakravarti, FS Collins, D Duggan, AB Feranil, LT Ho, YJ Hung, SC Hunt, K Hveem, JM Juang, AY Kesäniemi, J Kuusisto, M Laakso, TA Lakka, IT Lee, MF Leppert, TC Matise, L Moilanen, I Njølstad, U Peters, T Quertermous, R Rauramaa, JI Rotter, J Saramies, J Tuomilehto, M Uusitupa, TD Wang, M Boehnke, CA Haiman, YD Chen, C Kooperberg, TL Assimes, DC Crawford, CA Hsiung, KE North, KL Mohlke

Publication Date: 2013-03

Variant appearance in text: rs12286037

PubMed Link: 23555291

Variant Present in the following documents:

• pgen.1003379.s009.pdf

View BVdb publication page

---

Gene-centric meta-analysis of lipid traits in African, East Asian and Hispanic populations.

Plos One

CC Elbers, Y Guo, V Tragante, EP van Iperen, MB Lanktree, BA Castillo, F Chen, LR Yanek, MK Wojczynski, YR Li, B Ferwerda, CM Ballantyne, SG Buxbaum, YD Chen, WM Chen, LA Cupples, M Cushman, Y Duan, D Duggan, MK Evans, JK Fernandes, M Fornage, M Garcia, WT Garvey, N Glazer, F Gomez, TB Harris, I Halder, VJ Howard, MF Keller, MI Kamboh, C Kooperberg, SB Kritchevsky, A LaCroix, K Liu, Y Liu, K Musunuru, AB Newman, NC Onland-Moret, J Ordovas, I Peter, W Post, S Redline, SE Reis, R Saxena, PJ Schreiner, KA Volcik, X Wang, S Yusuf, AB Zonderland, SS Anand, DM Becker, B Psaty, DJ Rader, AP Reiner, SS Rich, JI Rotter, MM Sale, MY Tsai, IB Borecki, RA Hegele, S Kathiresan, MA Nalls, HA Taylor, H Hakonarson, S Sivapalaratnam, FW Asselbergs, F Drenos, JG Wilson, BJ Keating

Publication Date: 2012

Variant appearance in text: rs12286037

PubMed Link: 23236364

Variant Present in the following documents:

• pone.0050198.s002.pdf

View BVdb publication page

---

Single nucleotide polymorphisms (SNPs) involved in insulin resistance, weight regulation, lipid metabolism and inflammation in relation to metabolic syndrome: an epidemiological study.

Cardiovascular Diabetology

CM Povel, JM Boer, NC Onland-Moret, ME Dollé, EJ Feskens, YT van der Schouw

Publication Date: 2012-10-29

Variant appearance in text: rs12286037

PubMed Link: 23101478

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

American Journal Of Human Genetics

FW Asselbergs, Y Guo, EP van Iperen, S Sivapalaratnam, V Tragante, MB Lanktree, LA Lange, B Almoguera, YE Appelman, J Barnard, J Baumert, AL Beitelshees, TR Bhangale, YD Chen, TR Gaunt, Y Gong, JC Hopewell, T Johnson, ME Kleber, TY Langaee, M Li, YR Li, K Liu, CW McDonough, MF Meijs, RP Middelberg, K Musunuru, CP Nelson, JR O'Connell, S Padmanabhan, JS Pankow, N Pankratz, S Rafelt, R Rajagopalan, SP Romaine, NJ Schork, J Shaffer, H Shen, EN Smith, SE Tischfield, PJ van der Most, JV van Vliet-Ostaptchouk, N Verweij, KA Volcik, L Zhang, KR Bailey, KM Bailey, F Bauer, JM Boer, PS Braund, A Burt, PR Burton, SG Buxbaum, W Chen, RM Cooper-Dehoff, LA Cupples, JS deJong, C Delles, D Duggan, M Fornage, CE Furlong, N Glazer, JG Gums, C Hastie, MV Holmes, T Illig, SA Kirkland, M Kivimaki, R Klein, BE Klein, C Kooperberg, K Kottke-Marchant, M Kumari, AZ LaCroix, L Mallela, G Murugesan, J Ordovas, WH Ouwehand, WS Post, R Saxena, H Scharnagl, PJ Schreiner, T Shah, DC Shields, D Shimbo, SR Srinivasan, RP Stolk, DI Swerdlow, HA Taylor, EJ Topol, E Toskala, JL van Pelt, J van Setten, S Yusuf, JC Whittaker, AH Zwinderman, , SS Anand, AJ Balmforth, GS Berenson, CR Bezzina, BO Boehm, E Boerwinkle, JP Casas, MJ Caulfield, R Clarke, JM Connell, KJ Cruickshanks, KW Davidson, IN Day, PI de Bakker, PA Doevendans, AF Dominiczak, AS Hall, CA Hartman, C Hengstenberg, HL Hillege, MH Hofker, SE Humphries, GP Jarvik, JA Johnson, BM Kaess, S Kathiresan, W Koenig, DA Lawlor, W März, O Melander, BD Mitchell, GW Montgomery, PB Munroe, SS Murray, SJ Newhouse, NC Onland-Moret, N Poulter, B Psaty, S Redline, SS Rich, JI Rotter, H Schunkert, P Sever, AR Shuldiner, RL Silverstein, A Stanton, B Thorand, MD Trip, MY Tsai, P van der Harst, E van der Schoot, YT van der Schouw, WM Verschuren, H Watkins, AA Wilde, BH Wolffenbuttel, JB Whitfield, GK Hovingh, CM Ballantyne, C Wijmenga, MP Reilly, NG Martin, JG Wilson, DJ Rader, NJ Samani, AP Reiner, RA Hegele, JJ Kastelein, AD Hingorani, PJ Talmud, H Hakonarson, CC Elbers, BJ Keating, F Drenos

Publication Date: 2012-11-02

Variant appearance in text: rs12286037

PubMed Link: 23063622

Variant Present in the following documents:

• mmc4.xls
• mmc7.xls

View BVdb publication page

---

Association of genetic variants influencing lipid levels with coronary artery disease in Japanese individuals.

Plos One

F Takeuchi, M Isono, T Katsuya, M Yokota, K Yamamoto, T Nabika, K Shimokawa, E Nakashima, T Sugiyama, H Rakugi, S Yamaguchi, T Ogihara, Y Yamori, N Kato

Publication Date: 2012

Variant appearance in text: rs12286037

PubMed Link: 23050023

Variant Present in the following documents:

• pone.0046385.s002.xls

View BVdb publication page

---

Shared ancestral susceptibility to colorectal cancer and other nutrition related diseases.

Bmc Medical Genetics

S Huhn, M Bevier, A Rudolph, B Pardini, A Naccarati, R Hein, M Hoffmeister, L Vodickova, J Novotny, H Brenner, J Chang-Claude, K Hemminki, P Vodicka, A Försti

Publication Date: 2012-10-05

Variant appearance in text: rs12286037

PubMed Link: 23036011

Variant Present in the following documents:

• 1471-2350-13-94-S1.pdf

View BVdb publication page

---

A replication study of GWAS-derived lipid genes in Asian Indians: the chromosomal region 11q23.3 harbors loci contributing to triglycerides.

Plos One

TR Braun, LF Been, A Singhal, J Worsham, S Ralhan, GS Wander, JC Chambers, JS Kooner, CE Aston, DK Sanghera

Publication Date: 2012

Variant appearance in text: rs12286037

PubMed Link: 22623978

Variant Present in the following documents:

• Main text
• pone.0037056.s004.docx
• pone.0037056.s005.docx

View BVdb publication page

---

Integration of GWAS SNPs and tissue specific expression profiling reveal discrete eQTLs for human traits in blood and brain.

Neurobiology Of Disease

DG Hernandez, MA Nalls, M Moore, S Chong, A Dillman, D Trabzuni, JR Gibbs, M Ryten, S Arepalli, ME Weale, AB Zonderman, J Troncoso, R O'Brien, R Walker, C Smith, S Bandinelli, BJ Traynor, J Hardy, AB Singleton, MR Cookson

Publication Date: 2012-07

Variant appearance in text: rs12286037

PubMed Link: 22433082

Variant Present in the following documents:

• mmc1.xls

View BVdb publication page

---

Genome-wide association study identifies multiple loci influencing human serum metabolite levels.

Nature Genetics

J Kettunen, T Tukiainen, AP Sarin, A Ortega-Alonso, E Tikkanen, LP Lyytikäinen, AJ Kangas, P Soininen, P Würtz, K Silander, DM Dick, RJ Rose, MJ Savolainen, J Viikari, M Kähönen, T Lehtimäki, KH Pietiläinen, M Inouye, MI McCarthy, A Jula, J Eriksson, OT Raitakari, V Salomaa, J Kaprio, MR Järvelin, L Peltonen, M Perola, NB Freimer, M Ala-Korpela, A Palotie, S Ripatti

Publication Date: 2012-01-29

Variant appearance in text: rs12286037

PubMed Link: 22286219

Variant Present in the following documents:

• NIHMS444574-supplement-supplementary_table_2.xlsx

View BVdb publication page

---

A genome-wide scan for common variants affecting the rate of age-related cognitive decline.

Neurobiology Of Aging

PL De Jager, JM Shulman, LB Chibnik, BT Keenan, T Raj, RS Wilson, L Yu, SE Leurgans, D Tran, C Aubin, CD Anderson, A Biffi, JJ Corneveaux, MJ Huentelman, , J Rosand, MJ Daly, AJ Myers, EM Reiman, DA Bennett, DA Evans

Publication Date: 2012-05

Variant appearance in text: rs12286037

PubMed Link: 22054870

Variant Present in the following documents:

• NIHMS328602-supplement-01.doc

View BVdb publication page

---

Implications of discoveries from genome-wide association studies in current cardiovascular practice.

World Journal Of Cardiology

P Jeemon, K Pettigrew, C Sainsbury, D Prabhakaran, S Padmanabhan

Publication Date: 2011-07-26

Variant appearance in text: rs12286037

PubMed Link: 21860704

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Validation of candidate genes associated with cardiovascular risk factors in psychiatric patients.

Progress In Neuro-Psychopharmacology & Biological Psychiatry

A Windemuth, J de Leon, JW Goethe, HI Schwartz, S Woolley, M Susce, M Kocherla, K Bogaard, TR Holford, RL Seip, G Ruaño

Publication Date: 2012-03-30

Variant appearance in text: rs12286037

PubMed Link: 21851846

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA.

Plos Genetics

RS Fehrmann, RC Jansen, JH Veldink, HJ Westra, D Arends, MJ Bonder, J Fu, P Deelen, HJ Groen, A Smolonska, RK Weersma, RM Hofstra, WA Buurman, S Rensen, MG Wolfs, M Platteel, A Zhernakova, CC Elbers, EM Festen, G Trynka, MH Hofker, CG Saris, RA Ophoff, LH van den Berg, DA van Heel, C Wijmenga, GJ Te Meerman, L Franke

Publication Date: 2011-08

Variant appearance in text: rs12286037

PubMed Link: 21829388

Variant Present in the following documents:

• pgen.1002197.s016.xls

View BVdb publication page

---

A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.

Diabetes

AT Kraja, D Vaidya, JS Pankow, MO Goodarzi, TL Assimes, IJ Kullo, U Sovio, RA Mathias, YV Sun, N Franceschini, D Absher, G Li, Q Zhang, MF Feitosa, NL Glazer, T Haritunians, AL Hartikainen, JW Knowles, KE North, C Iribarren, B Kral, L Yanek, PF O'Reilly, MI McCarthy, C Jaquish, DJ Couper, A Chakravarti, BM Psaty, LC Becker, MA Province, E Boerwinkle, T Quertermous, L Palotie, MR Jarvelin, DM Becker, SL Kardia, JI Rotter, YD Chen, IB Borecki

Publication Date: 2011-04

Variant appearance in text: rs12286037

PubMed Link: 21386085

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.

Nature Genetics

H Schunkert, IR König, S Kathiresan, MP Reilly, TL Assimes, H Holm, M Preuss, AF Stewart, M Barbalic, C Gieger, D Absher, Z Aherrahrou, H Allayee, D Altshuler, SS Anand, K Andersen, JL Anderson, D Ardissino, SG Ball, AJ Balmforth, TA Barnes, DM Becker, LC Becker, K Berger, JC Bis, SM Boekholdt, E Boerwinkle, PS Braund, MJ Brown, MS Burnett, I Buysschaert, , JF Carlquist, L Chen, S Cichon, V Codd, RW Davies, G Dedoussis, A Dehghan, S Demissie, JM Devaney, P Diemert, R Do, A Doering, S Eifert, NE Mokhtari, SG Ellis, R Elosua, JC Engert, SE Epstein, U de Faire, M Fischer, AR Folsom, J Freyer, B Gigante, D Girelli, S Gretarsdottir, V Gudnason, JR Gulcher, E Halperin, N Hammond, SL Hazen, A Hofman, BD Horne, T Illig, C Iribarren, GT Jones, JW Jukema, MA Kaiser, LM Kaplan, JJ Kastelein, KT Khaw, JW Knowles, G Kolovou, A Kong, R Laaksonen, D Lambrechts, K Leander, G Lettre, M Li, W Lieb, C Loley, AJ Lotery, PM Mannucci, S Maouche, N Martinelli, PP McKeown, C Meisinger, T Meitinger, O Melander, PA Merlini, V Mooser, T Morgan, TW Mühleisen, JB Muhlestein, T Münzel, K Musunuru, J Nahrstaedt, CP Nelson, MM Nöthen, O Olivieri, RS Patel, CC Patterson, A Peters, F Peyvandi, L Qu, AA Quyyumi, DJ Rader, LS Rallidis, C Rice, FR Rosendaal, D Rubin, V Salomaa, ML Sampietro, MS Sandhu, E Schadt, A Schäfer, A Schillert, S Schreiber, J Schrezenmeir, SM Schwartz, DS Siscovick, M Sivananthan, S Sivapalaratnam, A Smith, TB Smith, JD Snoep, N Soranzo, JA Spertus, K Stark, K Stirrups, M Stoll, WH Tang, S Tennstedt, G Thorgeirsson, G Thorleifsson, M Tomaszewski, AG Uitterlinden, AM van Rij, BF Voight, NJ Wareham, GA Wells, HE Wichmann, PS Wild, C Willenborg, JC Witteman, BJ Wright, S Ye, T Zeller, A Ziegler, F Cambien, AH Goodall, LA Cupples, T Quertermous, W März, C Hengstenberg, S Blankenberg, WH Ouwehand, AS Hall, P Deloukas, JR Thompson, K Stefansson, R Roberts, U Thorsteinsdottir, CJ O'Donnell, R McPherson, J Erdmann, , NJ Samani

Publication Date: 2011-03-06

Variant appearance in text: rs12286037

PubMed Link: 21378990

Variant Present in the following documents:

• NIHMS287053-supplement-01.pdf

View BVdb publication page

---

Dense genotyping of candidate gene loci identifies variants associated with high-density lipoprotein cholesterol.

Circulation. Cardiovascular Genetics

AC Edmondson, PS Braund, IM Stylianou, AV Khera, CP Nelson, ML Wolfe, SL Derohannessian, BJ Keating, L Qu, J He, MD Tobin, M Tomaszewski, J Baumert, N Klopp, A Döring, B Thorand, M Li, MP Reilly, W Koenig, NJ Samani, DJ Rader

Publication Date: 2011-04

Variant appearance in text: rs12286037

PubMed Link: 21303902

Variant Present in the following documents:

• NIHMS280051-supplement-1.pdf

View BVdb publication page

---

Genome-wide significant associations for variants with minor allele frequency of 5% or less--an overview: A HuGE review.

American Journal Of Epidemiology

OA Panagiotou, E Evangelou, JP Ioannidis

Publication Date: 2010-10-15

Variant appearance in text: rs12286037

PubMed Link: 20876667

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Joint effects of common genetic variants from multiple genes and pathways on the risk of premature coronary artery disease.

American Heart Journal

JL Anderson, BD Horne, NJ Camp, JB Muhlestein, PN Hopkins, LA Cannon-Albright, CP Mower, JJ Park, JL Clarke, ZP Nicholas, JT McKinney, JF Carlquist

Publication Date: 2010-08

Variant appearance in text: rs12286037

PubMed Link: 20691829

Variant Present in the following documents:

• NIHMS209707-supplement-1.doc

View BVdb publication page

---

A single nucleotide polymorphism in APOA5 determines triglyceride levels in Hong Kong and Guangzhou Chinese.

European Journal Of Human Genetics : Ejhg

CQ Jiang, B Liu, BM Cheung, TH Lam, JM Lin, Y Li Jin, XJ Yue, KL Ong, S Tam, KS Wong, B Tomlinson, KS Lam, GN Thomas

Publication Date: 2010-11

Variant appearance in text: rs12286037

PubMed Link: 20571505

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Genome-wide association study of Lp-PLA(2) activity and mass in the Framingham Heart Study.

Plos Genetics

S Suchindran, D Rivedal, JR Guyton, T Milledge, X Gao, A Benjamin, J Rowell, GS Ginsburg, JJ McCarthy

Publication Date: 2010-04-29

Variant appearance in text: rs12286037

PubMed Link: 20442857

Variant Present in the following documents:

• Main text

View BVdb publication page

---

The genetics of obesity and the metabolic syndrome.

Endocrine, Metabolic & Immune Disorders Drug Targets

KL Monda, KE North, SC Hunt, DC Rao, MA Province, AT Kraja

Publication Date: 2010-06

Variant appearance in text: rs12286037

PubMed Link: 20406164

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Genome-wide association of lipid-lowering response to statins in combined study populations.

Plos One

MJ Barber, LM Mangravite, CL Hyde, DI Chasman, JD Smith, CA McCarty, X Li, RA Wilke, MJ Rieder, PT Williams, PM Ridker, A Chatterjee, JI Rotter, DA Nickerson, M Stephens, RM Krauss

Publication Date: 2010-03-22

Variant appearance in text: rs12286037

PubMed Link: 20339536

Variant Present in the following documents:

• pone.0009763.s008.xls

View BVdb publication page

---

Association between a literature-based genetic risk score and cardiovascular events in women.

Jama

NP Paynter, DI Chasman, G Paré, JE Buring, NR Cook, JP Miletich, PM Ridker

Publication Date: 2010-02-17

Variant appearance in text: rs12286037

PubMed Link: 20159871

Variant Present in the following documents:

• NIHMS173546-supplement-supplement_1.pdf

View BVdb publication page

---

Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.

American Journal Of Human Genetics

PJ Talmud, F Drenos, S Shah, T Shah, J Palmen, C Verzilli, TR Gaunt, J Pallas, R Lovering, K Li, JP Casas, R Sofat, M Kumari, S Rodriguez, T Johnson, SJ Newhouse, A Dominiczak, NJ Samani, M Caulfield, P Sever, A Stanton, DC Shields, S Padmanabhan, O Melander, C Hastie, C Delles, S Ebrahim, MG Marmot, GD Smith, DA Lawlor, PB Munroe, IN Day, M Kivimaki, J Whittaker, SE Humphries, AD Hingorani, , ,

Publication Date: 2009-11

Variant appearance in text: rs12286037

PubMed Link: 19913121

Variant Present in the following documents:

• mmc1.pdf
• mmc2.xls

View BVdb publication page

---

A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia.

Human Molecular Genetics

RA Hegele, MR Ban, N Hsueh, BA Kennedy, H Cao, GY Zou, S Anand, S Yusuf, MW Huff, J Wang

Publication Date: 2009-11-01

Variant appearance in text: rs12286037

PubMed Link: 19656773

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.

Nature Genetics

C Sabatti, SK Service, AL Hartikainen, A Pouta, S Ripatti, J Brodsky, CG Jones, NA Zaitlen, T Varilo, M Kaakinen, U Sovio, A Ruokonen, J Laitinen, E Jakkula, L Coin, C Hoggart, A Collins, H Turunen, S Gabriel, P Elliot, MI McCarthy, MJ Daly, MR Järvelin, NB Freimer, L Peltonen

Publication Date: 2009-01

Variant appearance in text: rs12286037

PubMed Link: 19060910

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants.

Human Molecular Genetics

KL Mohlke, M Boehnke, GR Abecasis

Publication Date: 2008-10-15

Variant appearance in text: rs12286037

PubMed Link: 18852197

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Newly identified loci that influence lipid concentrations and risk of coronary artery disease.

Nature Genetics

CJ Willer, S Sanna, AU Jackson, A Scuteri, LL Bonnycastle, R Clarke, SC Heath, NJ Timpson, SS Najjar, HM Stringham, J Strait, WL Duren, A Maschio, F Busonero, A Mulas, G Albai, AJ Swift, MA Morken, N Narisu, D Bennett, S Parish, H Shen, P Galan, P Meneton, S Hercberg, D Zelenika, WM Chen, Y Li, LJ Scott, PA Scheet, J Sundvall, RM Watanabe, R Nagaraja, S Ebrahim, DA Lawlor, Y Ben-Shlomo, G Davey-Smith, AR Shuldiner, R Collins, RN Bergman, M Uda, J Tuomilehto, A Cao, FS Collins, E Lakatta, GM Lathrop, M Boehnke, D Schlessinger, KL Mohlke, GR Abecasis

Publication Date: 2008-02

Variant appearance in text: rs12286037

PubMed Link: 18193043

Variant Present in the following documents:

• Main text
• NIHMS836655-supplement-Supplementary_Material.pdf

View BVdb publication page

---

Alternative transcript annotations:

Transcript	cDNA	Protein	Consequence	Exon	Intron
ENST00000227322.3	c.1179+667G>A	-	intron_variant	-	12/13
ENST00000429220.1	c.958+667G>A	-	intron_variant	-	10/11
ENST00000444935.1	c.1091+1428G>A	-	intron_variant	-	11/12
NM_001317086.2	c.1017+667G>A	-	intron_variant	-	11/12
NM_003904.5	c.1179+667G>A	-	intron_variant	-	12/13