Publications:

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Allele-specific enhancers mediate associations between LCAT and ABCA1 polymorphisms and HDL metabolism.

Plos One

AD Howard, X Wang, M Prasad, AD Sahu, R Aniba, M Miller, S Hannenhalli, YC Chang

Publication Date: 2019

Variant appearance in text: rs12286037

PMID: 31039173

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Frequency and phenotype consequence of APOC3 rare variants in patients with very low triglyceride levels.

Bmc Medical Genomics

DC Crawford, NA Restrepo, KE Diggins, E Farber-Eger, QS Wells

Publication Date: 2018-09-14

Variant appearance in text: rs12286037

PMID: 30255797

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Transforming growth factor-β signaling pathway-associated genes SMAD2 and TGFBR2 are implicated in metabolic syndrome in a Taiwanese population.

Scientific Reports

E Lin, PH Kuo, YL Liu, AC Yang, SJ Tsai

Publication Date: 2017-10-19

Variant appearance in text: rs12286037

PMID: 29051557

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Association of BUD13 polymorphisms with metabolic syndrome in Chinese population: a case-control study.

Lipids In Health And Disease

L Zhang, Y You, Y Wu, Y Zhang, M Wang, Y Song, X Liu, C Kou

Publication Date: 2017-06-28

Variant appearance in text: rs12286037

PMID: 28659142

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Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci.

Human Molecular Genetics

N Zubair, M Graff, J Luis Ambite, WS Bush, G Kichaev, Y Lu, A Manichaikul, WH Sheu, D Absher, TL Assimes, SJ Bielinski, EP Bottinger, P Buzkova, LM Chuang, RH Chung, B Cochran, L Dumitrescu, O Gottesman, JW Haessler, C Haiman, G Heiss, CA Hsiung, YJ Hung, CM Hwu, JJ Juang, L Le Marchand, IT Lee, WJ Lee, LA Lin, D Lin, SY Lin, RH Mackey, LW Martin, B Pasaniuc, U Peters, I Predazzi, T Quertermous, AP Reiner, J Robinson, JI Rotter, KK Ryckman, PJ Schreiner, E Stahl, R Tao, MY Tsai, LL Waite, TD Wang, S Buyske, YD Ida Chen, I Cheng, DC Crawford, RJF Loos, SS Rich, M Fornage, KE North, C Kooperberg, CL Carty

Publication Date: 2016-12-15

Variant appearance in text: rs12286037

PMID: 28426890

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Two-stage association study to identify the genetic susceptibility of a novel common variant of rs2075290 in ZPR1 to type 2 diabetes.

Scientific Reports

F Guan, Y Niu, T Zhang, S Liu, L Ma, T Qi, J Feng, H Zuo, G Li, X Liu, S Wang

Publication Date: 2016-07-14

Variant appearance in text: rs12286037

PMID: 27411854

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Distinct Patterns of Association of Variants at 11q23.3 Chromosomal Region with Coronary Artery Disease and Dyslipidemia in the Population of Andhra Pradesh, India.

Plos One

R Pranav Chand, AS Kumar, K Anuj, S Vishnupriya, B Mohan Reddy

Publication Date: 2016

Variant appearance in text: rs12286037

PMID: 27257688

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The interaction of Apolipoprotein A5 gene promoter region T-1131C polymorphism (rs12286037) and lifestyle modification on plasma triglyceride levels in Japanese.

Nutrition Research And Practice

M Yamasaki, PB Mutombo, M Iwamoto, A Nogi, M Hashimoto, T Nabika, K Shiwaku

Publication Date: 2015-08

Variant appearance in text: rs12286037

PMID: 26244076

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Gene-centric association signals for haemostasis and thrombosis traits identified with the HumanCVD BeadChip.

Thrombosis And Haemostasis

TR Gaunt, D Zabaneh, S Shah, A Guyatt, C Ladroue, M Kumari, F Drenos, T Shah, PJ Talmud, JP Casas, G Lowe, A Rumley, DA Lawlor, M Kivimaki, J Whittaker, AD Hingorani, SE Humphries, IN Day

Publication Date: 2013-11

Variant appearance in text: rs12286037

PMID: 24178511

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Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels.

Journal Of Lipid Research

Y Wu, AF Marvelle, J Li, DC Croteau-Chonka, AB Feranil, CW Kuzawa, Y Li, LS Adair, KL Mohlke

Publication Date: 2013-11

Variant appearance in text: rs12286037

PMID: 24023260

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Do genetic modifiers of high-density lipoprotein cholesterol and triglyceride levels also modify their response to a lifestyle intervention in the setting of obesity and type-2 diabetes mellitus?: The Action for Health in Diabetes (Look AHEAD) study.

Circulation. Cardiovascular Genetics

GS Huggins, GD Papandonatos, B Erar, LM Belalcazar, A Brautbar, C Ballantyne, AE Kitabchi, LE Wagenknecht, WC Knowler, HJ Pownall, RR Wing, I Peter, JM McCaffery,

Publication Date: 2013-08

Variant appearance in text: rs12286037

PMID: 23861364

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Single nucleotide polymorphisms (SNPs) involved in insulin resistance, weight regulation, lipid metabolism and inflammation in relation to metabolic syndrome: an epidemiological study.

Cardiovascular Diabetology

CM Povel, JM Boer, NC Onland-Moret, ME Dollé, EJ Feskens, YT van der Schouw

Publication Date: 2012-10-29

Variant appearance in text: rs12286037

PMID: 23101478

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A replication study of GWAS-derived lipid genes in Asian Indians: the chromosomal region 11q23.3 harbors loci contributing to triglycerides.

Plos One

TR Braun, LF Been, A Singhal, J Worsham, S Ralhan, GS Wander, JC Chambers, JS Kooner, CE Aston, DK Sanghera

Publication Date: 2012

Variant appearance in text: rs12286037

PMID: 22623978

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Implications of discoveries from genome-wide association studies in current cardiovascular practice.

World Journal Of Cardiology

P Jeemon, K Pettigrew, C Sainsbury, D Prabhakaran, S Padmanabhan

Publication Date: 2011-07-26

Variant appearance in text: rs12286037

PMID: 21860704

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Validation of candidate genes associated with cardiovascular risk factors in psychiatric patients.

Progress In Neuro-Psychopharmacology & Biological Psychiatry

A Windemuth, J de Leon, JW Goethe, HI Schwartz, S Woolley, M Susce, M Kocherla, K Bogaard, TR Holford, RL Seip, G Ruaño

Publication Date: 2012-03-30

Variant appearance in text: rs12286037

PMID: 21851846

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A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.

Diabetes

AT Kraja, D Vaidya, JS Pankow, MO Goodarzi, TL Assimes, IJ Kullo, U Sovio, RA Mathias, YV Sun, N Franceschini, D Absher, G Li, Q Zhang, MF Feitosa, NL Glazer, T Haritunians, AL Hartikainen, JW Knowles, KE North, C Iribarren, B Kral, L Yanek, PF O'Reilly, MI McCarthy, C Jaquish, DJ Couper, A Chakravarti, BM Psaty, LC Becker, MA Province, E Boerwinkle, T Quertermous, L Palotie, MR Jarvelin, DM Becker, SL Kardia, JI Rotter, YD Chen, IB Borecki

Publication Date: 2011-04

Variant appearance in text: rs12286037

PMID: 21386085

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Genome-wide significant associations for variants with minor allele frequency of 5% or less--an overview: A HuGE review.

American Journal Of Epidemiology

OA Panagiotou, E Evangelou, JP Ioannidis

Publication Date: 2010-10-15

Variant appearance in text: rs12286037

PMID: 20876667

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A single nucleotide polymorphism in APOA5 determines triglyceride levels in Hong Kong and Guangzhou Chinese.

European Journal Of Human Genetics : Ejhg

CQ Jiang, B Liu, BM Cheung, TH Lam, JM Lin, Y Li Jin, XJ Yue, KL Ong, S Tam, KS Wong, B Tomlinson, KS Lam, GN Thomas

Publication Date: 2010-11

Variant appearance in text: rs12286037

PMID: 20571505

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Genome-wide association study of Lp-PLA(2) activity and mass in the Framingham Heart Study.

Plos Genetics

S Suchindran, D Rivedal, JR Guyton, T Milledge, X Gao, A Benjamin, J Rowell, GS Ginsburg, JJ McCarthy

Publication Date: 2010-04-29

Variant appearance in text: rs12286037

PMID: 20442857

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The genetics of obesity and the metabolic syndrome.

Endocrine, Metabolic & Immune Disorders Drug Targets

KL Monda, KE North, SC Hunt, DC Rao, MA Province, AT Kraja

Publication Date: 2010-06

Variant appearance in text: rs12286037

PMID: 20406164

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A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia.

Human Molecular Genetics

RA Hegele, MR Ban, N Hsueh, BA Kennedy, H Cao, GY Zou, S Anand, S Yusuf, MW Huff, J Wang

Publication Date: 2009-11-01

Variant appearance in text: rs12286037

PMID: 19656773

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Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.

Nature Genetics

C Sabatti, SK Service, AL Hartikainen, A Pouta, S Ripatti, J Brodsky, CG Jones, NA Zaitlen, T Varilo, M Kaakinen, U Sovio, A Ruokonen, J Laitinen, E Jakkula, L Coin, C Hoggart, A Collins, H Turunen, S Gabriel, P Elliot, MI McCarthy, MJ Daly, MR Järvelin, NB Freimer, L Peltonen

Publication Date: 2009-01

Variant appearance in text: rs12286037

PMID: 19060910

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Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants.

Human Molecular Genetics

KL Mohlke, M Boehnke, GR Abecasis

Publication Date: 2008-10-15

Variant appearance in text: rs12286037

PMID: 18852197

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Newly identified loci that influence lipid concentrations and risk of coronary artery disease.

Nature Genetics

CJ Willer, S Sanna, AU Jackson, A Scuteri, LL Bonnycastle, R Clarke, SC Heath, NJ Timpson, SS Najjar, HM Stringham, J Strait, WL Duren, A Maschio, F Busonero, A Mulas, G Albai, AJ Swift, MA Morken, N Narisu, D Bennett, S Parish, H Shen, P Galan, P Meneton, S Hercberg, D Zelenika, WM Chen, Y Li, LJ Scott, PA Scheet, J Sundvall, RM Watanabe, R Nagaraja, S Ebrahim, DA Lawlor, Y Ben-Shlomo, G Davey-Smith, AR Shuldiner, R Collins, RN Bergman, M Uda, J Tuomilehto, A Cao, FS Collins, E Lakatta, GM Lathrop, M Boehnke, D Schlessinger, KL Mohlke, GR Abecasis

Publication Date: 2008-02

Variant appearance in text: rs12286037

PMID: 18193043

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Alternative transcript annotations:

Transcript	cDNA	Protein	Consequence	Exon	Intron
ENST00000227322.3	c.1179+667G>A	-	intron_variant	-	12/13
ENST00000429220.1	c.958+667G>A	-	intron_variant	-	10/11
ENST00000444935.1	c.1091+1428G>A	-	intron_variant	-	11/12
NM_001317086.2	c.1017+667G>A	-	intron_variant	-	11/12
NM_003904.5	c.1179+667G>A	-	intron_variant	-	12/13