Publications:

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Genome-wide association study of metabolic syndrome in Korean populations.

Plos One

SW Oh, JE Lee, E Shin, H Kwon, EK Choe, SY Choi, H Rhee, SH Choi

Publication Date: 2020

Variant appearance in text: rs6589566

PubMed Link: 31910446

Variant Present in the following documents:

• Main text

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Progressive effects of single-nucleotide polymorphisms on 16 phenotypic traits based on longitudinal data.

Genes & Genomics

D Li, H Kang, S Lee, S Won

Publication Date: 2020-04

Variant appearance in text: rs6589566

PubMed Link: 31902109

Variant Present in the following documents:

• Main text

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Effect of Interaction between Early Menarche and Genetic Polymorphisms on Triglyceride.

Oxidative Medicine And Cellular Longevity

HS Lee, S Leem, B Oh, T Park

Publication Date: 2019

Variant appearance in text: rs6589566

PubMed Link: 30931082

Variant Present in the following documents:

• Main text

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Multiple genotype-phenotype association study reveals intronic variant pair on SIDT2 associated with metabolic syndrome in a Korean population.

Human Genomics

S Moon, Y Lee, S Won, J Lee

Publication Date: 2018-11-01

Variant appearance in text: rs6589566

PubMed Link: 30382898

Variant Present in the following documents:

• 40246_2018_180_MOESM1_ESM.pdf
• aaaaaMain text

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Genetic and secondary causes of severe HDL deficiency and cardiovascular disease.

Journal Of Lipid Research

AS Geller, EY Polisecki, MR Diffenderfer, BF Asztalos, SK Karathanasis, RA Hegele, EJ Schaefer

Publication Date: 2018-12

Variant appearance in text: rs6589566

PubMed Link: 30333156

Variant Present in the following documents:

• Main text
• jlrM088203.pdf

View BVdb publication page

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New Common and Rare Variants Influencing Metabolic Syndrome and Its Individual Components in a Korean Population.

Scientific Reports

HS Lee, Y Kim, T Park

Publication Date: 2018-04-09

Variant appearance in text: rs6589566

PubMed Link: 29632305

Variant Present in the following documents:

• 41598_2018_23074_MOESM1_ESM.docx
• aaaaaMain text

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Prediction of cholesterol ratios within a Korean population.

Royal Society Open Science

JS Lee, HS Cheong, HD Shin

Publication Date: 2018-01

Variant appearance in text: rs6589566

PubMed Link: 29410832

Variant Present in the following documents:

• Main text
• rsos171204supp1.docx

View BVdb publication page

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Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study.

Plos Genetics

JP Davis, JR Huyghe, AE Locke, AU Jackson, X Sim, HM Stringham, TM Teslovich, RP Welch, C Fuchsberger, N Narisu, PS Chines, AJ Kangas, P Soininen, M Ala-Korpela, J Kuusisto, FS Collins, M Laakso, M Boehnke, KL Mohlke

Publication Date: 2017-10

Variant appearance in text: rs6589566

PubMed Link: 29084231

Variant Present in the following documents:

• pgen.1007079.s010.xlsx

View BVdb publication page

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Quantitative trait loci at the 11q23.3 chromosomal region related to dyslipidemia in the population of Andhra Pradesh, India.

Lipids In Health And Disease

R Pranavchand, BM Reddy

Publication Date: 2017-06-13

Variant appearance in text: rs6589566

PubMed Link: 28610615

Variant Present in the following documents:

• 12944_2017_507_MOESM2_ESM.docx
• 12944_2017_507_MOESM3_ESM.docx
• 12944_2017_507_MOESM4_ESM.docx
• 12944_2017_507_MOESM5_ESM.docx
• aaaaaMain text

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Whole genome sequencing and imputation in isolated populations identify genetic associations with medically-relevant complex traits.

Nature Communications

L Southam, A Gilly, D Süveges, AE Farmaki, J Schwartzentruber, I Tachmazidou, A Matchan, NW Rayner, E Tsafantakis, M Karaleftheri, Y Xue, G Dedoussis, E Zeggini

Publication Date: 2017-05-26

Variant appearance in text: rs6589566

PubMed Link: 28548082

Variant Present in the following documents:

• ncomms15606-s1.pdf

View BVdb publication page

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The impact of rare and low-frequency genetic variants in common disease.

Genome Biology

L Bomba, K Walter, N Soranzo

Publication Date: 2017-04-27

Variant appearance in text: rs6589566

PubMed Link: 28449691

Variant Present in the following documents:

• 13059_2017_1212_MOESM1_ESM.xlsx

View BVdb publication page

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Susceptibility loci for metabolic syndrome and metabolic components identified in Han Chinese: a multi-stage genome-wide association study.

Journal Of Cellular And Molecular Medicine

Y Zhu, D Zhang, D Zhou, Z Li, Z Li, L Fang, M Yang, Z Shan, H Li, J Chen, X Zhou, W Ye, S Yu, H Li, L Cai, C Liu, J Zhang, L Wang, Y Lai, L Ruan, Z Sun, S Zhang, H Wang, Y Liu, Y Xu, J Ling, C Xu, Y Zhang, D Lv, Z Yuan, J Zhang, Y Zhang, Y Shi, M Lai

Publication Date: 2017-06

Variant appearance in text: rs6589566

PubMed Link: 28371326

Variant Present in the following documents:

• JCMM-21-1106-s002.xlsx

View BVdb publication page

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Genetic determinants of clinical heterogeneity of the coronary artery disease in the population of Hyderabad, India.

Human Genomics

R Pranavchand, AS Kumar, BM Reddy

Publication Date: 2017-03-04

Variant appearance in text: rs6589566

PubMed Link: 28257648

Variant Present in the following documents:

• 40246_2017_99_MOESM3_ESM.docx
• 40246_2017_99_MOESM4_ESM.docx
• aaaaaMain text

View BVdb publication page

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Admixture mapping in two Mexican samples identifies significant associations of locus ancestry with triglyceride levels in the BUD13/ZNF259/APOA5 region and fine mapping points to rs964184 as the main driver of the association signal.

Plos One

EJ Parra, A Mazurek, CR Gignoux, A Sockell, M Agostino, AP Morris, LE Petty, CL Hanis, NJ Cox, A Valladares-Salgado, JE Below, M Cruz

Publication Date: 2017

Variant appearance in text: rs6589566

PubMed Link: 28245265

Variant Present in the following documents:

• pone.0172880.s002.xlsx

View BVdb publication page

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Combinatorial bZIP dimers display complex DNA-binding specificity landscapes.

Elife

JA Rodríguez-Martínez, AW Reinke, D Bhimsaria, AE Keating, AZ Ansari

Publication Date: 2017-02-10

Variant appearance in text: rs6589566

PubMed Link: 28186491

Variant Present in the following documents:

• elife-19272-supp1.xlsx

View BVdb publication page

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Multiphenotype association study of patients randomized to initiate antiretroviral regimens in AIDS Clinical Trials Group protocol A5202.

Pharmacogenetics And Genomics

A Verma, Y Bradford, SS Verma, SA Pendergrass, ES Daar, C Venuto, GD Morse, MD Ritchie, DW Haas

Publication Date: 2017-03

Variant appearance in text: rs6589566

PubMed Link: 28099408

Variant Present in the following documents:

• Main text

View BVdb publication page

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Genome-Wide Association Study Reveals Four Loci for Lipid Ratios in the Korean Population and the Constitutional Subgroup.

Plos One

T Kim, AY Park, Y Baek, S Cha

Publication Date: 2017

Variant appearance in text: rs6589566

PubMed Link: 28046027

Variant Present in the following documents:

• Main text

View BVdb publication page

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Novel genetic loci associated with long-term deterioration in blood lipid concentrations and coronary artery disease in European adults.

International Journal Of Epidemiology

TV Varga, A Kurbasic, M Aine, P Eriksson, A Ali, G Hindy, S Gustafsson, J Luan, D Shungin, Y Chen, CA Schulz, PM Nilsson, G Hallmans, I Barroso, P Deloukas, C Langenberg, RA Scott, NJ Wareham, L Lind, E Ingelsson, O Melander, M Orho-Melander, F Renström, PW Franks

Publication Date: 2017-08-01

Variant appearance in text: rs6589566

PubMed Link: 27864399

Variant Present in the following documents:

• dyw245_supplementary_method_2.docx
• dyw245_supplementary_table_7.xlsx

View BVdb publication page

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Association and interaction of APOA5, BUD13, CETP, LIPA and health-related behavior with metabolic syndrome in a Taiwanese population.

Scientific Reports

E Lin, PH Kuo, YL Liu, AC Yang, CF Kao, SJ Tsai

Publication Date: 2016-11-09

Variant appearance in text: rs6589566

PubMed Link: 27827461

Variant Present in the following documents:

• srep36830-s1.pdf

View BVdb publication page

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Two-stage association study to identify the genetic susceptibility of a novel common variant of rs2075290 in ZPR1 to type 2 diabetes.

Scientific Reports

F Guan, Y Niu, T Zhang, S Liu, L Ma, T Qi, J Feng, H Zuo, G Li, X Liu, S Wang

Publication Date: 2016-07-14

Variant appearance in text: rs6589566

PubMed Link: 27411854

Variant Present in the following documents:

• Main text

View BVdb publication page

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A Genome-Wide mQTL Analysis in Human Adipose Tissue Identifies Genetic Variants Associated with DNA Methylation, Gene Expression and Metabolic Traits.

Plos One

P Volkov, AH Olsson, L Gillberg, SW Jørgensen, C Brøns, KF Eriksson, L Groop, PA Jansson, E Nilsson, T Rönn, A Vaag, C Ling

Publication Date: 2016

Variant appearance in text: rs6589566

PubMed Link: 27322064

Variant Present in the following documents:

• pone.0157776.s004.xlsx

View BVdb publication page

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Distinct Patterns of Association of Variants at 11q23.3 Chromosomal Region with Coronary Artery Disease and Dyslipidemia in the Population of Andhra Pradesh, India.

Plos One

R Pranav Chand, AS Kumar, K Anuj, S Vishnupriya, B Mohan Reddy

Publication Date: 2016

Variant appearance in text: rs6589566

PubMed Link: 27257688

Variant Present in the following documents:

• Main text
• pone.0153720.s002.docx
• pone.0153720.s003.xlsx
• pone.0153720.s004.docx
• pone.0153720.s006.docx

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Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.

Scientific Reports

JE Below, EJ Parra, ER Gamazon, J Torres, S Krithika, S Candille, Y Lu, A Manichakul, J Peralta-Romero, Q Duan, Y Li, AP Morris, O Gottesman, E Bottinger, XQ Wang, KD Taylor, YD Ida Chen, JI Rotter, SS Rich, RJ Loos, H Tang, NJ Cox, M Cruz, CL Hanis, A Valladares-Salgado

Publication Date: 2016-01-19

Variant appearance in text: rs6589566

PubMed Link: 26780889

Variant Present in the following documents:

• srep19429-s3.xls

View BVdb publication page

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Effects of Polymorphisms in APOA4-APOA5-ZNF259-BUD13 Gene Cluster on Plasma Levels of Triglycerides and Risk of Coronary Heart Disease in a Chinese Han Population.

Plos One

Q Fu, X Tang, J Chen, L Su, M Zhang, L Wang, J Jing, L Zhou

Publication Date: 2015

Variant appearance in text: rs6589566

PubMed Link: 26397108

Variant Present in the following documents:

• Main text
• pone.0138652.s001.doc

View BVdb publication page

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Evaluation of transethnic fine mapping with population-specific and cosmopolitan imputation reference panels in diverse Asian populations.

European Journal Of Human Genetics : Ejhg

X Wang, CY Cheng, J Liao, X Sim, J Liu, KS Chia, ES Tai, P Little, CC Khor, T Aung, TY Wong, YY Teo

Publication Date: 2016-04

Variant appearance in text: rs6589566

PubMed Link: 26130488

Variant Present in the following documents:

• ejhg2015150x4.xls

View BVdb publication page

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Networks in Coronary Heart Disease Genetics As a Step towards Systems Epidemiology.

Plos One

F Drenos, E Grossi, M Buscema, SE Humphries

Publication Date: 2015

Variant appearance in text: rs6589566

PubMed Link: 25951190

Variant Present in the following documents:

• Main text
• pone.0125876.s006.xlsx
• pone.0125876.s007.xlsx
• pone.0125876.s008.xlsx

View BVdb publication page

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Genome-wide association study of metabolic syndrome in koreans.

Genomics & Informatics

SW Jeong, M Chung, SJ Park, SB Cho, KW Hong

Publication Date: 2014-12

Variant appearance in text: rs6589566

PubMed Link: 25705157

Variant Present in the following documents:

• Main text
• gni-12-187-s001.pdf

View BVdb publication page

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Association between CETP, MLXIPL, and TOMM40 polymorphisms and serum lipid levels in a Latvian population.

Meta Gene

I Radovica, D Fridmanis, I Silamikelis, L Nikitina-Zake, J Klovins

Publication Date: 2014-12

Variant appearance in text: rs6589566

PubMed Link: 25606439

Variant Present in the following documents:

• mmc1.docx

View BVdb publication page

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On the analysis of a repeated measure design in genome-wide association analysis.

International Journal Of Environmental Research And Public Health

Y Lee, S Park, S Moon, J Lee, RC Elston, W Lee, S Won

Publication Date: 2014-11-28

Variant appearance in text: rs6589566

PubMed Link: 25464127

Variant Present in the following documents:

• Main text

View BVdb publication page

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Genetic loci associated with changes in lipid levels leading to constitution-based discrepancy in Koreans.

Bmc Complementary And Alternative Medicine

SK Chung, H Yu, AY Park, JY Kim, S Cha

Publication Date: 2014-07-09

Variant appearance in text: rs6589566

PubMed Link: 25005712

Variant Present in the following documents:

• 1472-6882-14-230-S1.xls
• aaaaaMain text

View BVdb publication page

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Association between the MLX interacting protein-like, BUD13 homolog and zinc finger protein 259 gene polymorphisms and serum lipid levels.

Scientific Reports

LH Aung, RX Yin, JZ Wu, DF Wu, W Wang, H Li

Publication Date: 2014-07-03

Variant appearance in text: rs6589566

PubMed Link: 24989072

Variant Present in the following documents:

• Main text

View BVdb publication page

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Multiancestral analysis of inflammation-related genetic variants and C-reactive protein in the population architecture using genomics and epidemiology study.

Circulation. Cardiovascular Genetics

JM Kocarnik, SA Pendergrass, CL Carty, JS Pankow, FR Schumacher, I Cheng, P Durda, JL Ambite, E Deelman, NR Cook, S Liu, J Wactawski-Wende, C Hutter, K Brown-Gentry, S Wilson, LG Best, N Pankratz, CP Hong, SA Cole, VS Voruganti, P Bůžkova, NW Jorgensen, NS Jenny, LR Wilkens, CA Haiman, LN Kolonel, A Lacroix, K North, R Jackson, L Le Marchand, LA Hindorff, DC Crawford, M Gross, U Peters

Publication Date: 2014-04

Variant appearance in text: rs6589566

PubMed Link: 24622110

Variant Present in the following documents:

• NIHMS575195-supplement-000173_-_Supplemental_Material.pdf

View BVdb publication page

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Effects of apolipoprotein A5 haplotypes on the ratio of triglyceride to high-density lipoprotein cholesterol and the risk for metabolic syndrome in Koreans.

Lipids In Health And Disease

S Cha, H Yu, AY Park, KH Song

Publication Date: 2014-03-12

Variant appearance in text: rs6589566

PubMed Link: 24618354

Variant Present in the following documents:

• 1476-511X-13-45-S2.xls
• aaaaaMain text

View BVdb publication page

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ChIP-seq in steatohepatitis and normal liver tissue identifies candidate disease mechanisms related to progression to cancer.

Bmc Medical Genomics

M Bysani, O Wallerman, S Bornelöv, K Zatloukal, J Komorowski, C Wadelius

Publication Date: 2013-11-08

Variant appearance in text: rs6589566

PubMed Link: 24206787

Variant Present in the following documents:

• 1755-8794-6-50-S2.docx

View BVdb publication page

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Properties of local interactions and their potential value in complementing genome-wide association studies.

Plos One

W Wei, A Gyenesei, CA Semple, CS Haley

Publication Date: 2013

Variant appearance in text: rs6589566

PubMed Link: 23940718

Variant Present in the following documents:

• pone.0071203.s003.xlsx

View BVdb publication page

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Impact of HDL genetic risk scores on coronary artery calcified plaque and mortality in individuals with type 2 diabetes from the Diabetes Heart Study.

Cardiovascular Diabetology

LM Raffield, AJ Cox, FC Hsu, MC Ng, CD Langefeld, JJ Carr, BI Freedman, DW Bowden

Publication Date: 2013-06-25

Variant appearance in text: rs6589566

PubMed Link: 23799899

Variant Present in the following documents:

• Main text

View BVdb publication page

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Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.

American Journal Of Human Genetics

MA Coram, Q Duan, TJ Hoffmann, T Thornton, JW Knowles, NA Johnson, HM Ochs-Balcom, TA Donlon, LW Martin, CB Eaton, JG Robinson, NJ Risch, X Zhu, C Kooperberg, Y Li, AP Reiner, H Tang

Publication Date: 2013-06-06

Variant appearance in text: rs6589566

PubMed Link: 23726366

Variant Present in the following documents:

• Main text

View BVdb publication page

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The association of common SNPs and haplotypes in CETP gene with HDL cholesterol levels in Latvian population.

Plos One

I Radovica, D Fridmanis, I Vaivade, L Nikitina-Zake, J Klovins

Publication Date: 2013

Variant appearance in text: rs6589566

PubMed Link: 23675527

Variant Present in the following documents:

• Main text
• pone.0064191.s002.docx

View BVdb publication page

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Improvement in prediction of coronary heart disease risk over conventional risk factors using SNPs identified in genome-wide association studies.

Plos One

JL Bolton, MC Stewart, JF Wilson, N Anderson, JF Price

Publication Date: 2013

Variant appearance in text: rs6589566

PubMed Link: 23468967

Variant Present in the following documents:

• pone.0057310.s005.pdf

View BVdb publication page

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Single nucleotide polymorphisms (SNPs) involved in insulin resistance, weight regulation, lipid metabolism and inflammation in relation to metabolic syndrome: an epidemiological study.

Cardiovascular Diabetology

CM Povel, JM Boer, NC Onland-Moret, ME Dollé, EJ Feskens, YT van der Schouw

Publication Date: 2012-10-29

Variant appearance in text: rs6589566

PubMed Link: 23101478

Variant Present in the following documents:

• Main text

View BVdb publication page

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Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

American Journal Of Human Genetics

FW Asselbergs, Y Guo, EP van Iperen, S Sivapalaratnam, V Tragante, MB Lanktree, LA Lange, B Almoguera, YE Appelman, J Barnard, J Baumert, AL Beitelshees, TR Bhangale, YD Chen, TR Gaunt, Y Gong, JC Hopewell, T Johnson, ME Kleber, TY Langaee, M Li, YR Li, K Liu, CW McDonough, MF Meijs, RP Middelberg, K Musunuru, CP Nelson, JR O'Connell, S Padmanabhan, JS Pankow, N Pankratz, S Rafelt, R Rajagopalan, SP Romaine, NJ Schork, J Shaffer, H Shen, EN Smith, SE Tischfield, PJ van der Most, JV van Vliet-Ostaptchouk, N Verweij, KA Volcik, L Zhang, KR Bailey, KM Bailey, F Bauer, JM Boer, PS Braund, A Burt, PR Burton, SG Buxbaum, W Chen, RM Cooper-Dehoff, LA Cupples, JS deJong, C Delles, D Duggan, M Fornage, CE Furlong, N Glazer, JG Gums, C Hastie, MV Holmes, T Illig, SA Kirkland, M Kivimaki, R Klein, BE Klein, C Kooperberg, K Kottke-Marchant, M Kumari, AZ LaCroix, L Mallela, G Murugesan, J Ordovas, WH Ouwehand, WS Post, R Saxena, H Scharnagl, PJ Schreiner, T Shah, DC Shields, D Shimbo, SR Srinivasan, RP Stolk, DI Swerdlow, HA Taylor, EJ Topol, E Toskala, JL van Pelt, J van Setten, S Yusuf, JC Whittaker, AH Zwinderman, , SS Anand, AJ Balmforth, GS Berenson, CR Bezzina, BO Boehm, E Boerwinkle, JP Casas, MJ Caulfield, R Clarke, JM Connell, KJ Cruickshanks, KW Davidson, IN Day, PI de Bakker, PA Doevendans, AF Dominiczak, AS Hall, CA Hartman, C Hengstenberg, HL Hillege, MH Hofker, SE Humphries, GP Jarvik, JA Johnson, BM Kaess, S Kathiresan, W Koenig, DA Lawlor, W März, O Melander, BD Mitchell, GW Montgomery, PB Munroe, SS Murray, SJ Newhouse, NC Onland-Moret, N Poulter, B Psaty, S Redline, SS Rich, JI Rotter, H Schunkert, P Sever, AR Shuldiner, RL Silverstein, A Stanton, B Thorand, MD Trip, MY Tsai, P van der Harst, E van der Schoot, YT van der Schouw, WM Verschuren, H Watkins, AA Wilde, BH Wolffenbuttel, JB Whitfield, GK Hovingh, CM Ballantyne, C Wijmenga, MP Reilly, NG Martin, JG Wilson, DJ Rader, NJ Samani, AP Reiner, RA Hegele, JJ Kastelein, AD Hingorani, PJ Talmud, H Hakonarson, CC Elbers, BJ Keating, F Drenos

Publication Date: 2012-11-02

Variant appearance in text: rs6589566

PubMed Link: 23063622

Variant Present in the following documents:

• mmc4.xls

View BVdb publication page

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Association of genetic variants influencing lipid levels with coronary artery disease in Japanese individuals.

Plos One

F Takeuchi, M Isono, T Katsuya, M Yokota, K Yamamoto, T Nabika, K Shimokawa, E Nakashima, T Sugiyama, H Rakugi, S Yamaguchi, T Ogihara, Y Yamori, N Kato

Publication Date: 2012

Variant appearance in text: rs6589566

PubMed Link: 23050023

Variant Present in the following documents:

• pone.0046385.s002.xls

View BVdb publication page

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TRIB1 constitutes a molecular link between regulation of sleep and lipid metabolism in humans.

Translational Psychiatry

HM Ollila, S Utge, E Kronholm, V Aho, W Van Leeuwen, K Silander, T Partonen, M Perola, J Kaprio, V Salomaa, M Sallinen, M Härmä, T Porkka-Heiskanen, T Paunio

Publication Date: 2012-03-20

Variant appearance in text: rs6589566

PubMed Link: 22832862

Variant Present in the following documents:

• tp201220x1.pdf

View BVdb publication page

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Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study.

Lancet (London, England)

BF Voight, GM Peloso, M Orho-Melander, R Frikke-Schmidt, M Barbalic, MK Jensen, G Hindy, H Hólm, EL Ding, T Johnson, H Schunkert, NJ Samani, R Clarke, JC Hopewell, JF Thompson, M Li, G Thorleifsson, C Newton-Cheh, K Musunuru, JP Pirruccello, D Saleheen, L Chen, A Stewart, A Schillert, U Thorsteinsdottir, G Thorgeirsson, S Anand, JC Engert, T Morgan, J Spertus, M Stoll, K Berger, N Martinelli, D Girelli, PP McKeown, CC Patterson, SE Epstein, J Devaney, MS Burnett, V Mooser, S Ripatti, I Surakka, MS Nieminen, J Sinisalo, ML Lokki, M Perola, A Havulinna, U de Faire, B Gigante, E Ingelsson, T Zeller, P Wild, PI de Bakker, OH Klungel, AH Maitland-van der Zee, BJ Peters, A de Boer, DE Grobbee, PW Kamphuisen, VH Deneer, CC Elbers, NC Onland-Moret, MH Hofker, C Wijmenga, WM Verschuren, JM Boer, YT van der Schouw, A Rasheed, P Frossard, S Demissie, C Willer, R Do, JM Ordovas, GR Abecasis, M Boehnke, KL Mohlke, MJ Daly, C Guiducci, NP Burtt, A Surti, E Gonzalez, S Purcell, S Gabriel, J Marrugat, J Peden, J Erdmann, P Diemert, C Willenborg, IR König, M Fischer, C Hengstenberg, A Ziegler, I Buysschaert, D Lambrechts, F Van de Werf, KA Fox, NE El Mokhtari, D Rubin, J Schrezenmeir, S Schreiber, A Schäfer, J Danesh, S Blankenberg, R Roberts, R McPherson, H Watkins, AS Hall, K Overvad, E Rimm, E Boerwinkle, A Tybjaerg-Hansen, LA Cupples, MP Reilly, O Melander, PM Mannucci, D Ardissino, D Siscovick, R Elosua, K Stefansson, CJ O'Donnell, V Salomaa, DJ Rader, L Peltonen, SM Schwartz, D Altshuler, S Kathiresan

Publication Date: 2012-08-11

Variant appearance in text: rs6589566

PubMed Link: 22607825

Variant Present in the following documents:

• Main text

View BVdb publication page

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Integration of GWAS SNPs and tissue specific expression profiling reveal discrete eQTLs for human traits in blood and brain.

Neurobiology Of Disease

DG Hernandez, MA Nalls, M Moore, S Chong, A Dillman, D Trabzuni, JR Gibbs, M Ryten, S Arepalli, ME Weale, AB Zonderman, J Troncoso, R O'Brien, R Walker, C Smith, S Bandinelli, BJ Traynor, J Hardy, AB Singleton, MR Cookson

Publication Date: 2012-07

Variant appearance in text: rs6589566

PubMed Link: 22433082

Variant Present in the following documents:

• mmc1.xls

View BVdb publication page

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Genome-wide association study identifies multiple loci influencing human serum metabolite levels.

Nature Genetics

J Kettunen, T Tukiainen, AP Sarin, A Ortega-Alonso, E Tikkanen, LP Lyytikäinen, AJ Kangas, P Soininen, P Würtz, K Silander, DM Dick, RJ Rose, MJ Savolainen, J Viikari, M Kähönen, T Lehtimäki, KH Pietiläinen, M Inouye, MI McCarthy, A Jula, J Eriksson, OT Raitakari, V Salomaa, J Kaprio, MR Järvelin, L Peltonen, M Perola, NB Freimer, M Ala-Korpela, A Palotie, S Ripatti

Publication Date: 2012-01-29

Variant appearance in text: rs6589566

PubMed Link: 22286219

Variant Present in the following documents:

• NIHMS444574-supplement-supplementary_table_2.xlsx

View BVdb publication page

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A genome-wide scan for common variants affecting the rate of age-related cognitive decline.

Neurobiology Of Aging

PL De Jager, JM Shulman, LB Chibnik, BT Keenan, T Raj, RS Wilson, L Yu, SE Leurgans, D Tran, C Aubin, CD Anderson, A Biffi, JJ Corneveaux, MJ Huentelman, , J Rosand, MJ Daly, AJ Myers, EM Reiman, DA Bennett, DA Evans

Publication Date: 2012-05

Variant appearance in text: rs6589566

PubMed Link: 22054870

Variant Present in the following documents:

• NIHMS328602-supplement-01.doc

View BVdb publication page

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Implications of discoveries from genome-wide association studies in current cardiovascular practice.

World Journal Of Cardiology

P Jeemon, K Pettigrew, C Sainsbury, D Prabhakaran, S Padmanabhan

Publication Date: 2011-07-26

Variant appearance in text: rs6589566

PubMed Link: 21860704

Variant Present in the following documents:

• Main text

View BVdb publication page

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Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA.

Plos Genetics

RS Fehrmann, RC Jansen, JH Veldink, HJ Westra, D Arends, MJ Bonder, J Fu, P Deelen, HJ Groen, A Smolonska, RK Weersma, RM Hofstra, WA Buurman, S Rensen, MG Wolfs, M Platteel, A Zhernakova, CC Elbers, EM Festen, G Trynka, MH Hofker, CG Saris, RA Ophoff, LH van den Berg, DA van Heel, C Wijmenga, GJ Te Meerman, L Franke

Publication Date: 2011-08

Variant appearance in text: rs6589566

PubMed Link: 21829388

Variant Present in the following documents:

• pgen.1002197.s016.xls

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Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration.

European Heart Journal

A Angelakopoulou, T Shah, R Sofat, S Shah, DJ Berry, J Cooper, J Palmen, I Tzoulaki, A Wong, BJ Jefferis, N Maniatis, F Drenos, B Gigante, R Hardy, RC Laxton, K Leander, A Motterle, IA Simpson, L Smeeth, A Thomson, C Verzilli, D Kuh, H Ireland, J Deanfield, M Caulfield, C Wallace, N Samani, PB Munroe, M Lathrop, FG Fowkes, M Marmot, PH Whincup, JC Whittaker, U de Faire, M Kivimaki, M Kumari, E Hypponen, C Power, SE Humphries, PJ Talmud, J Price, RW Morris, S Ye, JP Casas, AD Hingorani

Publication Date: 2012-02

Variant appearance in text: rs6589566

PubMed Link: 21804106

Variant Present in the following documents:

• Main text

View BVdb publication page

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A gene-centric association scan for Coagulation Factor VII levels in European and African Americans: the Candidate Gene Association Resource (CARe) Consortium.

Human Molecular Genetics

KC Taylor, LA Lange, D Zabaneh, E Lange, BJ Keating, W Tang, NL Smith, JA Delaney, M Kumari, A Hingorani, KE North, M Kivimaki, RP Tracy, CJ O'Donnell, AR Folsom, D Green, SE Humphries, AP Reiner

Publication Date: 2011-09-01

Variant appearance in text: rs6589566

PubMed Link: 21676895

Variant Present in the following documents:

• Main text

View BVdb publication page

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Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.

Nature Genetics

H Schunkert, IR König, S Kathiresan, MP Reilly, TL Assimes, H Holm, M Preuss, AF Stewart, M Barbalic, C Gieger, D Absher, Z Aherrahrou, H Allayee, D Altshuler, SS Anand, K Andersen, JL Anderson, D Ardissino, SG Ball, AJ Balmforth, TA Barnes, DM Becker, LC Becker, K Berger, JC Bis, SM Boekholdt, E Boerwinkle, PS Braund, MJ Brown, MS Burnett, I Buysschaert, , JF Carlquist, L Chen, S Cichon, V Codd, RW Davies, G Dedoussis, A Dehghan, S Demissie, JM Devaney, P Diemert, R Do, A Doering, S Eifert, NE Mokhtari, SG Ellis, R Elosua, JC Engert, SE Epstein, U de Faire, M Fischer, AR Folsom, J Freyer, B Gigante, D Girelli, S Gretarsdottir, V Gudnason, JR Gulcher, E Halperin, N Hammond, SL Hazen, A Hofman, BD Horne, T Illig, C Iribarren, GT Jones, JW Jukema, MA Kaiser, LM Kaplan, JJ Kastelein, KT Khaw, JW Knowles, G Kolovou, A Kong, R Laaksonen, D Lambrechts, K Leander, G Lettre, M Li, W Lieb, C Loley, AJ Lotery, PM Mannucci, S Maouche, N Martinelli, PP McKeown, C Meisinger, T Meitinger, O Melander, PA Merlini, V Mooser, T Morgan, TW Mühleisen, JB Muhlestein, T Münzel, K Musunuru, J Nahrstaedt, CP Nelson, MM Nöthen, O Olivieri, RS Patel, CC Patterson, A Peters, F Peyvandi, L Qu, AA Quyyumi, DJ Rader, LS Rallidis, C Rice, FR Rosendaal, D Rubin, V Salomaa, ML Sampietro, MS Sandhu, E Schadt, A Schäfer, A Schillert, S Schreiber, J Schrezenmeir, SM Schwartz, DS Siscovick, M Sivananthan, S Sivapalaratnam, A Smith, TB Smith, JD Snoep, N Soranzo, JA Spertus, K Stark, K Stirrups, M Stoll, WH Tang, S Tennstedt, G Thorgeirsson, G Thorleifsson, M Tomaszewski, AG Uitterlinden, AM van Rij, BF Voight, NJ Wareham, GA Wells, HE Wichmann, PS Wild, C Willenborg, JC Witteman, BJ Wright, S Ye, T Zeller, A Ziegler, F Cambien, AH Goodall, LA Cupples, T Quertermous, W März, C Hengstenberg, S Blankenberg, WH Ouwehand, AS Hall, P Deloukas, JR Thompson, K Stefansson, R Roberts, U Thorsteinsdottir, CJ O'Donnell, R McPherson, J Erdmann, , NJ Samani

Publication Date: 2011-03-06

Variant appearance in text: rs6589566

PubMed Link: 21378990

Variant Present in the following documents:

• NIHMS287053-supplement-01.pdf

View BVdb publication page

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Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.

Plos Genetics

G Lettre, CD Palmer, T Young, KG Ejebe, H Allayee, EJ Benjamin, F Bennett, DW Bowden, A Chakravarti, A Dreisbach, DN Farlow, AR Folsom, M Fornage, T Forrester, E Fox, CA Haiman, J Hartiala, TB Harris, SL Hazen, SR Heckbert, BE Henderson, JN Hirschhorn, BJ Keating, SB Kritchevsky, E Larkin, M Li, ME Rudock, CA McKenzie, JB Meigs, YA Meng, TH Mosley, AB Newman, CH Newton-Cheh, DN Paltoo, GJ Papanicolaou, N Patterson, WS Post, BM Psaty, AN Qasim, L Qu, DJ Rader, S Redline, MP Reilly, AP Reiner, SS Rich, JI Rotter, Y Liu, P Shrader, DS Siscovick, WH Tang, HA Taylor, RP Tracy, RS Vasan, KM Waters, R Wilks, JG Wilson, RR Fabsitz, SB Gabriel, S Kathiresan, E Boerwinkle

Publication Date: 2011-02-10

Variant appearance in text: rs6589566

PubMed Link: 21347282

Variant Present in the following documents:

• pgen.1001300.s016.doc
• pgen.1001300.s017.doc

View BVdb publication page

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Genetic predisposition influences plasma lipids of participants on habitual diet, but not the response to reductions in dietary intake of saturated fatty acids.

Atherosclerosis

CG Walker, RJ Loos, AD Olson, GS Frost, BA Griffin, JA Lovegrove, TA Sanders, SA Jebb

Publication Date: 2011-04

Variant appearance in text: rs6589566

PubMed Link: 21292264

Variant Present in the following documents:

• mmc2.pdf
• mmc3.doc
• mmc4.pdf
• mmc5.pdf

View BVdb publication page

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Genome-wide significant associations for variants with minor allele frequency of 5% or less--an overview: A HuGE review.

American Journal Of Epidemiology

OA Panagiotou, E Evangelou, JP Ioannidis

Publication Date: 2010-10-15

Variant appearance in text: rs6589566

PubMed Link: 20876667

Variant Present in the following documents:

• Main text

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The genetics of obesity and the metabolic syndrome.

Endocrine, Metabolic & Immune Disorders Drug Targets

KL Monda, KE North, SC Hunt, DC Rao, MA Province, AT Kraja

Publication Date: 2010-06

Variant appearance in text: rs6589566

PubMed Link: 20406164

Variant Present in the following documents:

• Main text

View BVdb publication page

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Genome-wide association of lipid-lowering response to statins in combined study populations.

Plos One

MJ Barber, LM Mangravite, CL Hyde, DI Chasman, JD Smith, CA McCarty, X Li, RA Wilke, MJ Rieder, PT Williams, PM Ridker, A Chatterjee, JI Rotter, DA Nickerson, M Stephens, RM Krauss

Publication Date: 2010-03-22

Variant appearance in text: rs6589566

PubMed Link: 20339536

Variant Present in the following documents:

• pone.0009763.s008.xls

View BVdb publication page

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Association between a literature-based genetic risk score and cardiovascular events in women.

Jama

NP Paynter, DI Chasman, G Paré, JE Buring, NR Cook, JP Miletich, PM Ridker

Publication Date: 2010-02-17

Variant appearance in text: rs6589566

PubMed Link: 20159871

Variant Present in the following documents:

• NIHMS173546-supplement-supplement_1.pdf

View BVdb publication page

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Genome-wide association analyses of North American Rheumatoid Arthritis Consortium and Framingham Heart Study data utilizing genome-wide linkage results.

Bmc Proceedings

YJ Yoo, D Pinnaduwage, D Waggott, SB Bull, L Sun

Publication Date: 2009-12-15

Variant appearance in text: rs6589566

PubMed Link: 20017967

Variant Present in the following documents:

• Main text

View BVdb publication page

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A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia.

Human Molecular Genetics

RA Hegele, MR Ban, N Hsueh, BA Kennedy, H Cao, GY Zou, S Anand, S Yusuf, MW Huff, J Wang

Publication Date: 2009-11-01

Variant appearance in text: rs6589566

PubMed Link: 19656773

Variant Present in the following documents:

• Main text

View BVdb publication page

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Integrated associations of genotypes with multiple blood biomarkers linked to coronary heart disease risk.

Human Molecular Genetics

F Drenos, PJ Talmud, JP Casas, L Smeeth, J Palmen, SE Humphries, AD Hingorani

Publication Date: 2009-06-15

Variant appearance in text: rs6589566

PubMed Link: 19336475

Variant Present in the following documents:

• Main text

View BVdb publication page

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Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia.

American Journal Of Human Genetics

C Wallace, SJ Newhouse, P Braund, F Zhang, M Tobin, M Falchi, K Ahmadi, RJ Dobson, AC Marçano, C Hajat, P Burton, P Deloukas, M Brown, JM Connell, A Dominiczak, GM Lathrop, J Webster, M Farrall, T Spector, NJ Samani, MJ Caulfield, PB Munroe

Publication Date: 2008-01

Variant appearance in text: rs6589566

PubMed Link: 18179892

Variant Present in the following documents:

• Main text

View BVdb publication page

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Alternative transcript annotations:

Transcript	cDNA	Protein	Consequence	Exon	Intron
ENST00000227322.3	c.1179+451C>A	-	intron_variant	-	12/13
ENST00000429220.1	c.958+451C>A	-	intron_variant	-	10/11
ENST00000444935.1	c.1091+1212C>A	-	intron_variant	-	11/12
NM_001317086.2	c.1017+451C>A	-	intron_variant	-	11/12
NM_003904.5	c.1179+451C>A	-	intron_variant	-	12/13