Next-generation whole exome sequencing to delineate the genetic basis of primary congenital glaucoma.
Scientific Reports
Rauf, Bushra B; Khan, Shahid Y SY; Jiao, Xiaodong X; Irum, Bushra B; Ashfaq, Ramla R; Zehra, Mubashra M; Khan, Asma A AA; Naeem, Muhammad Asif MA; Shahzad, Mohsin M; Riazuddin, Sheikh S; Hejtmancik, J Fielding JF; Riazuddin, S Amer SA
Polymorphisms of the 11q23.3 Locus Affect the Risk and Mortality of Coronary Artery Disease.
Journal Of Clinical Medicine
Iwanicki, Tomasz T; Iwanicka, Joanna J; Balcerzyk-Matić, Anna A; Nowak, Tomasz T; Mizia-Stec, Katarzyna K; Bańka, Paweł P; Filipecki, Artur A; Krauze, Jolanta J; Jarosz, Alicja A; Górczyńska-Kosiorz, Sylwia S; Ochalska-Tyka, Anna A; Żak, Iwona I; Niemiec, Paweł P
Circulating bilirubin levels and risk of colorectal cancer: serological and Mendelian randomization analyses.
Bmc Medicine
Seyed Khoei, Nazlisadat N; Jenab, Mazda M; Murphy, Neil N; Banbury, Barbara L BL; Carreras-Torres, Robert R; Viallon, Vivian V; Kühn, Tilman T; Bueno-de-Mesquita, Bas B; Aleksandrova, Krasimira K; Cross, Amanda J AJ; Weiderpass, Elisabete E; Stepien, Magdalena M; Bulmer, Andrew A; Tjønneland, Anne A; Boutron-Ruault, Marie-Christine MC; Severi, Gianluca G; Carbonnel, Franck F; Katzke, Verena V; Boeing, Heiner H; Bergmann, Manuela M MM; Trichopoulou, Antonia A; Karakatsani, Anna A; Martimianaki, Georgia G; Palli, Domenico D; Tagliabue, Giovanna G; Panico, Salvatore S; Tumino, Rosario R; Sacerdote, Carlotta C; Skeie, Guri G; Merino, Susana S; Bonet, Catalina C; Rodríguez-Barranco, Miguel M; Gil, Leire L; Chirlaque, Maria-Dolores MD; Ardanaz, Eva E; Myte, Robin R; Hultdin, Johan J; Perez-Cornago, Aurora A; Aune, Dagfinn D; Tsilidis, Konstantinos K KK; Albanes, Demetrius D; Baron, John A JA; Berndt, Sonja I SI; Bézieau, Stéphane S; Brenner, Hermann H; Campbell, Peter T PT; Casey, Graham G; Chan, Andrew T AT; Chang-Claude, Jenny J; Chanock, Stephen J SJ; Cotterchio, Michelle M; Gallinger, Steven S; Gruber, Stephen B SB; Haile, Robert W RW; Hampe, Jochen J; Hoffmeister, Michael M; Hopper, John L JL; Hsu, Li L; Huyghe, Jeroen R JR; Jenkins, Mark A MA; Joshi, Amit D AD; Kampman, Ellen E; Larsson, Susanna C SC; Le Marchand, Loic L; Li, Christopher I CI; Li, Li L; Lindblom, Annika A; Lindor, Noralane M NM; Martín, Vicente V; Moreno, Victor V; Newcomb, Polly A PA; Offit, Kenneth K; Ogino, Shuji S; Parfrey, Patrick S PS; Pharoah, Paul D P PDP; Rennert, Gad G; Sakoda, Lori C LC; Schafmayer, Clemens C; Schmit, Stephanie L SL; Schoen, Robert E RE; Slattery, Martha L ML; Thibodeau, Stephen N SN; Ulrich, Cornelia M CM; van Duijnhoven, Franzel J B FJB; Weigl, Korbinian K; Weinstein, Stephanie J SJ; White, Emily E; Wolk, Alicja A; Woods, Michael O MO; Wu, Anna H AH; Zhang, Xuehong X; Ferrari, Pietro P; Anton, Gabriele G; Peters, Annette A; Peters, Ulrike U; Gunter, Marc J MJ; Wagner, Karl-Heinz KH; Freisling, Heinz H
Genome-wide association studies in Samoans give insight into the genetic architecture of fasting serum lipid levels.
Journal Of Human Genetics
Carlson, Jenna C JC; Weeks, Daniel E DE; Hawley, Nicola L NL; Sun, Guangyun G; Cheng, Hong H; Naseri, Take T; Reupena, Muagututi'a Sefuiva MS; Tuitele, John J; Deka, Ranjan R; McGarvey, Stephen T ST; Minster, Ryan L RL
Admixture mapping in two Mexican samples identifies significant associations of locus ancestry with triglyceride levels in the BUD13/ZNF259/APOA5 region and fine mapping points to rs964184 as the main driver of the association signal.
Plos One
Parra, Esteban J EJ; Mazurek, Andrew A; Gignoux, Christopher R CR; Sockell, Alexandra A; Agostino, Michael M; Morris, Andrew P AP; Petty, Lauren E LE; Hanis, Craig L CL; Cox, Nancy J NJ; Valladares-Salgado, Adan A; Below, Jennifer E JE; Cruz, Miguel M
Distinct Patterns of Association of Variants at 11q23.3 Chromosomal Region with Coronary Artery Disease and Dyslipidemia in the Population of Andhra Pradesh, India.
Genetic analysis of long-lived families reveals novel variants influencing high density-lipoprotein cholesterol.
Frontiers In Genetics
Feitosa, Mary F MF; Wojczynski, Mary K MK; Straka, Robert R; Kammerer, Candace M CM; Lee, Joseph H JH; Kraja, Aldi T AT; Christensen, Kaare K; Newman, Anne B AB; Province, Michael A MA; Borecki, Ingrid B IB
Use of systems biology approaches to analysis of genome-wide association studies of myocardial infarction and blood cholesterol in the nurses' health study and health professionals' follow-up study.
Plos One
Reilly, Dermot D; Hao, Ke K; Jensen, Majken K MK; Girman, Cynthia J CJ; Rimm, Eric B EB
Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels.
Journal Of Lipid Research
Wu, Ying Y; Marvelle, Amanda F AF; Li, Jin J; Croteau-Chonka, Damien C DC; Feranil, Alan B AB; Kuzawa, Christopher W CW; Li, Yun Y; Adair, Linda S LS; Mohlke, Karen L KL
GUESS-ing polygenic associations with multiple phenotypes using a GPU-based evolutionary stochastic search algorithm.
Plos Genetics
Bottolo, Leonardo L; Chadeau-Hyam, Marc M; Hastie, David I DI; Zeller, Tanja T; Liquet, Benoit B; Newcombe, Paul P; Yengo, Loic L; Wild, Philipp S PS; Schillert, Arne A; Ziegler, Andreas A; Nielsen, Sune F SF; Butterworth, Adam S AS; Ho, Weang Kee WK; Castagné, Raphaële R; Munzel, Thomas T; Tregouet, David D; Falchi, Mario M; Cambien, François F; Nordestgaard, Børge G BG; Fumeron, Fredéric F; Tybjærg-Hansen, Anne A; Froguel, Philippe P; Danesh, John J; Petretto, Enrico E; Blankenberg, Stefan S; Tiret, Laurence L; Richardson, Sylvia S
Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained.
Plos Genetics
Wu, Ying Y; Waite, Lindsay L LL; Jackson, Anne U AU; Sheu, Wayne H-H WH; Buyske, Steven S; Absher, Devin D; Arnett, Donna K DK; Boerwinkle, Eric E; Bonnycastle, Lori L LL; Carty, Cara L CL; Cheng, Iona I; Cochran, Barbara B; Croteau-Chonka, Damien C DC; Dumitrescu, Logan L; Eaton, Charles B CB; Franceschini, Nora N; Guo, Xiuqing X; Henderson, Brian E BE; Hindorff, Lucia A LA; Kim, Eric E; Kinnunen, Leena L; Komulainen, Pirjo P; Lee, Wen-Jane WJ; Le Marchand, Loic L; Lin, Yi Y; Lindström, Jaana J; Lingaas-Holmen, Oddgeir O; Mitchell, Sabrina L SL; Narisu, Narisu N; Robinson, Jennifer G JG; Schumacher, Fred F; Stančáková, Alena A; Sundvall, Jouko J; Sung, Yun-Ju YJ; Swift, Amy J AJ; Wang, Wen-Chang WC; Wilkens, Lynne L; Wilsgaard, Tom T; Young, Alicia M AM; Adair, Linda S LS; Ballantyne, Christie M CM; Bůžková, Petra P; Chakravarti, Aravinda A; Collins, Francis S FS; Duggan, David D; Feranil, Alan B AB; Ho, Low-Tone LT; Hung, Yi-Jen YJ; Hunt, Steven C SC; Hveem, Kristian K; Juang, Jyh-Ming J JM; Kesäniemi, Antero Y AY; Kuusisto, Johanna J; Laakso, Markku M; Lakka, Timo A TA; Lee, I-Te IT; Leppert, Mark F MF; Matise, Tara C TC; Moilanen, Leena L; Njølstad, Inger I; Peters, Ulrike U; Quertermous, Thomas T; Rauramaa, Rainer R; Rotter, Jerome I JI; Saramies, Jouko J; Tuomilehto, Jaakko J; Uusitupa, Matti M; Wang, Tzung-Dau TD; Boehnke, Michael M; Haiman, Christopher A CA; Chen, Yii-Der I YD; Kooperberg, Charles C; Assimes, Themistocles L TL; Crawford, Dana C DC; Hsiung, Chao A CA; North, Kari E KE; Mohlke, Karen L KL
Identification and MS-assisted interpretation of genetically influenced NMR signals in human plasma.
Genome Medicine
Raffler, Johannes J; Römisch-Margl, Werner W; Petersen, Ann-Kristin AK; Pagel, Philipp P; Blöchl, Florian F; Hengstenberg, Christian C; Illig, Thomas T; Meisinger, Christa C; Stark, Klaus K; Wichmann, H-Erich HE; Adamski, Jerzy J; Gieger, Christian C; Kastenmüller, Gabi G; Suhre, Karsten K
Variants in the APOA5 gene region and the response to combination therapy with statins and fenofibric acid in a randomized clinical trial of individuals with mixed dyslipidemia.
Atherosclerosis
Brautbar, Ariel A; Covarrubias, Daniel D; Belmont, John J; Lara-Garduno, Fremiet F; Virani, Salim S SS; Jones, Peter H PH; Leal, Suzanne M SM; Ballantyne, Christie M CM