Publications:

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Quantile-dependent expressivity of postprandial lipemia.

Plos One

PT Williams

Publication Date: 2020

Variant appearance in text: rs2266788

PubMed Link: 32101585

Variant Present in the following documents:

• Main text

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Genome-wide association study of metabolic syndrome in Korean populations.

Plos One

SW Oh, JE Lee, E Shin, H Kwon, EK Choe, SY Choi, H Rhee, SH Choi

Publication Date: 2020

Variant appearance in text: rs2266788

PubMed Link: 31910446

Variant Present in the following documents:

• Main text

View BVdb publication page

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A comprehensive study of metabolite genetics reveals strong pleiotropy and heterogeneity across time and context.

Nature Communications

A Gallois, J Mefford, A Ko, A Vaysse, H Julienne, M Ala-Korpela, M Laakso, N Zaitlen, P Pajukanta, H Aschard

Publication Date: 2019-10-21

Variant appearance in text: rs2266788

PubMed Link: 31636271

Variant Present in the following documents:

• 41467_2019_12703_MOESM11_ESM.xlsx
• 41467_2019_12703_MOESM3_ESM.xlsx
• 41467_2019_12703_MOESM4_ESM.xlsx
• 41467_2019_12703_MOESM6_ESM.xlsx
• 41467_2019_12703_MOESM7_ESM.xlsx
• 41467_2019_12703_MOESM8_ESM.xlsx
• 41467_2019_Article_12703.pdf
• aaaaaMain text

View BVdb publication page

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Introducing the first whole genomes of nationals from the United Arab Emirates.

Scientific Reports

HS AlSafar, M Al-Ali, GD Elbait, MH Al-Maini, D Ruta, B Peramo, A Henschel, GK Tay

Publication Date: 2019-10-11

Variant appearance in text: rs2266788

PubMed Link: 31604968

Variant Present in the following documents:

• 41598_2019_50876_MOESM1_ESM.xlsx

View BVdb publication page

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Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight adipocyte biology.

Nature Communications

Y Tanigawa, J Li, JM Justesen, H Horn, M Aguirre, C DeBoever, C Chang, B Narasimhan, K Lage, T Hastie, CY Park, G Bejerano, E Ingelsson, MA Rivas

Publication Date: 2019-09-06

Variant appearance in text: rs2266788

PubMed Link: 31492854

Variant Present in the following documents:

• 41467_2019_11953_MOESM6_ESM.xlsx

View BVdb publication page

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Evolutionary history of disease-susceptibility loci identified in longitudinal exome-wide association studies.

Molecular Genetics & Genomic Medicine

Y Yasukochi, J Sakuma, I Takeuchi, K Kato, M Oguri, T Fujimaki, H Horibe, Y Yamada

Publication Date: 2019-09

Variant appearance in text: rs2266788

PubMed Link: 31402603

Variant Present in the following documents:

• MGG3-7-e925-s001.pdf

View BVdb publication page

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Evaluation of the appropriate predictive contributor and diagnostic threshold for the cardio-metabolic syndrome in Chinese Uyghur adults.

Bmc Public Health

Z Zhang, S Fan, Z Xue, J Yuan, Z Zhou, T Wang, J Liu, A Bawudun, N Nurmamat, Y Wang, Z Yang

Publication Date: 2019-05-21

Variant appearance in text: rs2266788

PubMed Link: 31113427

Variant Present in the following documents:

• Main text

View BVdb publication page

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Metabolic Syndrome Prediction Using Machine Learning Models with Genetic and Clinical Information from a Nonobese Healthy Population.

Genomics & Informatics

EK Choe, H Rhee, S Lee, E Shin, SW Oh, JE Lee, SH Choi

Publication Date: 2018-12

Variant appearance in text: rs2266788

PubMed Link: 30602092

Variant Present in the following documents:

• Main text

View BVdb publication page

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Identification of 12 novel loci that confer susceptibility to early-onset dyslipidemia.

International Journal Of Molecular Medicine

Y Yamada, K Kato, M Oguri, H Horibe, T Fujimaki, Y Yasukochi, I Takeuchi, J Sakuma

Publication Date: 2019-01

Variant appearance in text: rs2266788

PubMed Link: 30365130

Variant Present in the following documents:

• Main text

View BVdb publication page

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Role of genetic and environmental factors in DNA methylation of lipid metabolism.

Genes & Diseases

Z He, R Zhang, F Jiang, W Hou, C Hu

Publication Date: 2018-03

Variant appearance in text: rs2266788

PubMed Link: 30258929

Variant Present in the following documents:

• Main text

View BVdb publication page

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Global genetic diversity of human apolipoproteins and effects on cardiovascular disease risk.

Journal Of Lipid Research

Y Zhou, R Mägi, L Milani, VM Lauschke

Publication Date: 2018-10

Variant appearance in text: rs2266788

PubMed Link: 30076208

Variant Present in the following documents:

• Main text

View BVdb publication page

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Integrating Genes Affecting Coronary Artery Disease in Functional Networks by Multi-OMICs Approach.

Frontiers In Cardiovascular Medicine

B Vilne, H Schunkert

Publication Date: 2018

Variant appearance in text: rs2266788

PubMed Link: 30065929

Variant Present in the following documents:

• Main text

View BVdb publication page

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Influence of APOA5 Locus on the Treatment Efficacy of Three Statins: Evidence From a Randomized Pilot Study in Chinese Subjects.

Frontiers In Pharmacology

S Hua, C Ma, J Zhang, J Li, W Wu, N Xu, G Luo, J Zhao

Publication Date: 2018

Variant appearance in text: rs2266788

PubMed Link: 29695967

Variant Present in the following documents:

• Main text

View BVdb publication page

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Sequence Analysis of APOA5 Among the Kuwaiti Population Identifies Association of rs2072560, rs2266788, and rs662799 With TG and VLDL Levels.

Frontiers In Genetics

AA Jasim, SA Al-Bustan, W Al-Kandari, A Al-Serri, H AlAskar

Publication Date: 2018

Variant appearance in text: rs2266788

PubMed Link: 29686695

Variant Present in the following documents:

• Main text
• Table2.pdf

View BVdb publication page

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Genetic variants in mRNA untranslated regions.

Wiley Interdisciplinary Reviews. Rna

M Steri, ML Idda, MB Whalen, V Orrù

Publication Date: 2018-07

Variant appearance in text: rs2266788

PubMed Link: 29582564

Variant Present in the following documents:

• Main text

View BVdb publication page

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Identification of three genetic variants as novel susceptibility loci for body mass index in a Japanese population.

Physiological Genomics

Y Yasukochi, J Sakuma, I Takeuchi, K Kato, M Oguri, T Fujimaki, H Horibe, Y Yamada

Publication Date: 2018-03-01

Variant appearance in text: rs2266788

PubMed Link: 29341862

Variant Present in the following documents:

• Main text

View BVdb publication page

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Genome-wide association study identifies a missense variant at APOA5 for coronary artery disease in Multi-Ethnic Cohorts from Southeast Asia.

Scientific Reports

Y Han, R Dorajoo, X Chang, L Wang, CC Khor, X Sim, CY Cheng, Y Shi, YC Tham, W Zhao, ML Chee, C Sabanayagam, ML Chee, N Tan, TY Wong, ES Tai, J Liu, DYT Goh, JM Yuan, WP Koh, RM van Dam, AF Low, MY Chan, Y Friedlander, CK Heng

Publication Date: 2017-12-20

Variant appearance in text: rs2266788

PubMed Link: 29263402

Variant Present in the following documents:

• Main text

View BVdb publication page

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Identity-by-Descent Mapping Identifies Major Locus for Serum Triglycerides in Amerindians Largely Explained by an APOC3 Founder Mutation.

Circulation. Cardiovascular Genetics

WC Hsueh, AK Nair, S Kobes, P Chen, HHH Göring, TI Pollin, A Malhotra, WC Knowler, LJ Baier, RL Hanson

Publication Date: 2017-12

Variant appearance in text: rs2266788

PubMed Link: 29237685

Variant Present in the following documents:

• Main text
• NIHMS917321-supplement-001809_-_Supplemental_material.pdf

View BVdb publication page

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Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study.

Plos Genetics

JP Davis, JR Huyghe, AE Locke, AU Jackson, X Sim, HM Stringham, TM Teslovich, RP Welch, C Fuchsberger, N Narisu, PS Chines, AJ Kangas, P Soininen, M Ala-Korpela, J Kuusisto, FS Collins, M Laakso, M Boehnke, KL Mohlke

Publication Date: 2017-10

Variant appearance in text: rs2266788

PubMed Link: 29084231

Variant Present in the following documents:

• pgen.1007079.s010.xlsx

View BVdb publication page

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Exome chip meta-analysis identifies novel loci and East Asian-specific coding variants that contribute to lipid levels and coronary artery disease.

Nature Genetics

X Lu, GM Peloso, DJ Liu, Y Wu, H Zhang, W Zhou, J Li, CS Tang, R Dorajoo, H Li, J Long, X Guo, M Xu, CN Spracklen, Y Chen, X Liu, Y Zhang, CC Khor, J Liu, L Sun, L Wang, YT Gao, Y Hu, K Yu, Y Wang, CYY Cheung, F Wang, J Huang, Q Fan, Q Cai, S Chen, J Shi, X Yang, W Zhao, WH Sheu, SS Cherny, M He, AB Feranil, LS Adair, P Gordon-Larsen, S Du, R Varma, YI Chen, XO Shu, KSL Lam, TY Wong, SK Ganesh, Z Mo, K Hveem, LG Fritsche, JB Nielsen, HF Tse, Y Huo, CY Cheng, YE Chen, W Zheng, ES Tai, W Gao, X Lin, W Huang, G Abecasis, , S Kathiresan, KL Mohlke, T Wu, PC Sham, D Gu, CJ Willer

Publication Date: 2017-12

Variant appearance in text: rs2266788

PubMed Link: 29083407

Variant Present in the following documents:

• NIHMS909133-supplement-1.docx

View BVdb publication page

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Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers.

Plos One

LC Pilling, JL Atkins, MO Duff, RN Beaumont, SE Jones, J Tyrrell, CL Kuo, KS Ruth, MA Tuke, H Yaghootkar, AR Wood, A Murray, MN Weedon, LW Harries, GA Kuchel, L Ferrucci, TM Frayling, D Melzer

Publication Date: 2017

Variant appearance in text: rs2266788

PubMed Link: 28957414

Variant Present in the following documents:

• pone.0185083.s004.xlsx

View BVdb publication page

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Evaluating the Causal Relation of ApoA-IV with Disease-Related Traits - A Bidirectional Two-sample Mendelian Randomization Study.

Scientific Reports

S Mack, S Coassin, J Vaucher, F Kronenberg, C Lamina,

Publication Date: 2017-08-18

Variant appearance in text: rs2266788

PubMed Link: 28821713

Variant Present in the following documents:

• Main text

View BVdb publication page

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A GDF15 3' UTR variant, rs1054564, results in allele-specific translational repression of GDF15 by hsa-miR-1233-3p.

Plos One

MS Teng, LA Hsu, SH Juan, WC Lin, MC Lee, CW Su, S Wu, YL Ko

Publication Date: 2017

Variant appearance in text: rs2266788

PubMed Link: 28806401

Variant Present in the following documents:

• Main text

View BVdb publication page

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The association between apolipoprotein A1-C3-A5 gene cluster promoter polymorphisms and risk of ischemic stroke in the northern Chinese Han population.

The Journal Of International Medical Research

Y Wang, F Liu, L Li, S Deng, Z He

Publication Date: 2017-12

Variant appearance in text: rs2266788

PubMed Link: 28635360

Variant Present in the following documents:

• Main text

View BVdb publication page

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Whole genome sequencing and imputation in isolated populations identify genetic associations with medically-relevant complex traits.

Nature Communications

L Southam, A Gilly, D Süveges, AE Farmaki, J Schwartzentruber, I Tachmazidou, A Matchan, NW Rayner, E Tsafantakis, M Karaleftheri, Y Xue, G Dedoussis, E Zeggini

Publication Date: 2017-05-26

Variant appearance in text: rs2266788

PubMed Link: 28548082

Variant Present in the following documents:

• ncomms15606-s1.pdf

View BVdb publication page

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Identification of eight genetic variants as novel determinants of dyslipidemia in Japanese by exome-wide association studies.

Oncotarget

Y Yamada, J Sakuma, I Takeuchi, Y Yasukochi, K Kato, M Oguri, T Fujimaki, H Horibe, M Muramatsu, M Sawabe, Y Fujiwara, Y Taniguchi, S Obuchi, H Kawai, S Shinkai, S Mori, T Arai, M Tanaka

Publication Date: 2017-06-13

Variant appearance in text: rs2266788

PubMed Link: 28473662

Variant Present in the following documents:

• Main text
• oncotarget-08-38950-s002.docx
• oncotarget-08-38950-s012.docx
• oncotarget-08-38950-s013.docx
• oncotarget-08-38950-s015.docx
• oncotarget-08-38950-s016.docx
• oncotarget-08-38950-s018.docx
• oncotarget-08-38950-s019.docx

View BVdb publication page

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Low LDL cholesterol, PCSK9 and HMGCR genetic variation, and risk of Alzheimer's disease and Parkinson's disease: Mendelian randomisation study.

Bmj (Clinical Research Ed.)

M Benn, BG Nordestgaard, R Frikke-Schmidt, A Tybjærg-Hansen

Publication Date: 2017-04-24

Variant appearance in text: rs2266788

PubMed Link: 28438747

Variant Present in the following documents:

• benm033277.ww1.pdf

View BVdb publication page

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Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci.

Human Molecular Genetics

N Zubair, M Graff, J Luis Ambite, WS Bush, G Kichaev, Y Lu, A Manichaikul, WH Sheu, D Absher, TL Assimes, SJ Bielinski, EP Bottinger, P Buzkova, LM Chuang, RH Chung, B Cochran, L Dumitrescu, O Gottesman, JW Haessler, C Haiman, G Heiss, CA Hsiung, YJ Hung, CM Hwu, JJ Juang, L Le Marchand, IT Lee, WJ Lee, LA Lin, D Lin, SY Lin, RH Mackey, LW Martin, B Pasaniuc, U Peters, I Predazzi, T Quertermous, AP Reiner, J Robinson, JI Rotter, KK Ryckman, PJ Schreiner, E Stahl, R Tao, MY Tsai, LL Waite, TD Wang, S Buyske, YD Ida Chen, I Cheng, DC Crawford, RJF Loos, SS Rich, M Fornage, KE North, C Kooperberg, CL Carty

Publication Date: 2016-12-15

Variant appearance in text: rs2266788

PubMed Link: 28426890

Variant Present in the following documents:

• ddw358_supp.docx

View BVdb publication page

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SNPs in microRNA target sites and their potential role in human disease.

Open Biology

A Moszyńska, M Gebert, JF Collawn, R Bartoszewski

Publication Date: 2017-04

Variant appearance in text: rs2266788

PubMed Link: 28381629

Variant Present in the following documents:

• Main text

View BVdb publication page

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Susceptibility loci for metabolic syndrome and metabolic components identified in Han Chinese: a multi-stage genome-wide association study.

Journal Of Cellular And Molecular Medicine

Y Zhu, D Zhang, D Zhou, Z Li, Z Li, L Fang, M Yang, Z Shan, H Li, J Chen, X Zhou, W Ye, S Yu, H Li, L Cai, C Liu, J Zhang, L Wang, Y Lai, L Ruan, Z Sun, S Zhang, H Wang, Y Liu, Y Xu, J Ling, C Xu, Y Zhang, D Lv, Z Yuan, J Zhang, Y Zhang, Y Shi, M Lai

Publication Date: 2017-06

Variant appearance in text: rs2266788

PubMed Link: 28371326

Variant Present in the following documents:

• Main text
• JCMM-21-1106-s002.xlsx

View BVdb publication page

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Admixture mapping in two Mexican samples identifies significant associations of locus ancestry with triglyceride levels in the BUD13/ZNF259/APOA5 region and fine mapping points to rs964184 as the main driver of the association signal.

Plos One

EJ Parra, A Mazurek, CR Gignoux, A Sockell, M Agostino, AP Morris, LE Petty, CL Hanis, NJ Cox, A Valladares-Salgado, JE Below, M Cruz

Publication Date: 2017

Variant appearance in text: rs2266788

PubMed Link: 28245265

Variant Present in the following documents:

• pone.0172880.s002.xlsx

View BVdb publication page

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Associations of triglyceride levels with longevity and frailty: A Mendelian randomization analysis.

Scientific Reports

Z Liu, S Burgess, Z Wang, W Deng, X Chu, J Cai, Y Zhu, J Shi, X Xie, Y Wang, L Jin, X Wang

Publication Date: 2017-01-30

Variant appearance in text: rs2266788

PubMed Link: 28134330

Variant Present in the following documents:

• Main text

View BVdb publication page

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Genome-Wide Association Study Reveals Four Loci for Lipid Ratios in the Korean Population and the Constitutional Subgroup.

Plos One

T Kim, AY Park, Y Baek, S Cha

Publication Date: 2017

Variant appearance in text: rs2266788

PubMed Link: 28046027

Variant Present in the following documents:

• Main text

View BVdb publication page

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Novel genetic loci associated with long-term deterioration in blood lipid concentrations and coronary artery disease in European adults.

International Journal Of Epidemiology

TV Varga, A Kurbasic, M Aine, P Eriksson, A Ali, G Hindy, S Gustafsson, J Luan, D Shungin, Y Chen, CA Schulz, PM Nilsson, G Hallmans, I Barroso, P Deloukas, C Langenberg, RA Scott, NJ Wareham, L Lind, E Ingelsson, O Melander, M Orho-Melander, F Renström, PW Franks

Publication Date: 2017-08-01

Variant appearance in text: rs2266788

PubMed Link: 27864399

Variant Present in the following documents:

• dyw245_supplementary_method_2.docx
• dyw245_supplementary_table_7.xlsx

View BVdb publication page

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Association and interaction of APOA5, BUD13, CETP, LIPA and health-related behavior with metabolic syndrome in a Taiwanese population.

Scientific Reports

E Lin, PH Kuo, YL Liu, AC Yang, CF Kao, SJ Tsai

Publication Date: 2016-11-09

Variant appearance in text: rs2266788

PubMed Link: 27827461

Variant Present in the following documents:

• srep36830-s1.pdf

View BVdb publication page

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The antihypertensive MTHFR gene polymorphism rs17367504-G is a possible novel protective locus for preeclampsia.

Journal Of Hypertension

LC Thomsen, NS McCarthy, PE Melton, G Cadby, R Austgulen, OK Nygård, MP Johnson, S Brennecke, EK Moses, L Bjørge, AC Iversen

Publication Date: 2017-01

Variant appearance in text: rs2266788

PubMed Link: 27755385

Variant Present in the following documents:

• jhype-35-132-s001.docx

View BVdb publication page

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Single Nucleotide Polymorphisms in Cellular Drug Transporters Are Associated with Intolerance to Antiretroviral Therapy in Brazilian HIV-1 Positive Individuals.

Plos One

MB Arruda, F Campagnari, TB de Almeida, JC Couto-Fernandez, A Tanuri, CC Cardoso

Publication Date: 2016

Variant appearance in text: rs2266788

PubMed Link: 27648838

Variant Present in the following documents:

• pone.0163170.s001.xlsx

View BVdb publication page

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Analysis with the exome array identifies multiple new independent variants in lipid loci.

Human Molecular Genetics

S Kanoni, NG Masca, KE Stirrups, TV Varga, HR Warren, RA Scott, L Southam, W Zhang, H Yaghootkar, M Müller-Nurasyid, A Couto Alves, RJ Strawbridge, L Lataniotis, N An Hashim, C Besse, A Boland, PS Braund, JM Connell, A Dominiczak, AE Farmaki, S Franks, H Grallert, JH Jansson, M Karaleftheri, S Keinänen-Kiukaanniemi, A Matchan, D Pasko, A Peters, N Poulter, NW Rayner, F Renström, O Rolandsson, M Sabater-Lleal, B Sennblad, P Sever, D Shields, A Silveira, AV Stanton, K Strauch, M Tomaszewski, E Tsafantakis, M Waldenberger, AI Blakemore, G Dedoussis, SA Escher, JS Kooner, MI McCarthy, CN Palmer, , A Hamsten, MJ Caulfield, TM Frayling, MD Tobin, MR Jarvelin, E Zeggini, C Gieger, JC Chambers, NJ Wareham, PB Munroe, PW Franks, NJ Samani, P Deloukas

Publication Date: 2016-09-15

Variant appearance in text: rs2266788

PubMed Link: 27466198

Variant Present in the following documents:

• Main text

View BVdb publication page

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Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015) : Jeddah, Kingdom of Saudi Arabia. 30 November - 3 December 2015.

Bmc Genomics

.

Publication Date: 2016-07-20

Variant appearance in text: rs2266788

PubMed Link: 27454254

Variant Present in the following documents:

• Main text

View BVdb publication page

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Two-stage association study to identify the genetic susceptibility of a novel common variant of rs2075290 in ZPR1 to type 2 diabetes.

Scientific Reports

F Guan, Y Niu, T Zhang, S Liu, L Ma, T Qi, J Feng, H Zuo, G Li, X Liu, S Wang

Publication Date: 2016-07-14

Variant appearance in text: rs2266788

PubMed Link: 27411854

Variant Present in the following documents:

• Main text

View BVdb publication page

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A Genome-Wide mQTL Analysis in Human Adipose Tissue Identifies Genetic Variants Associated with DNA Methylation, Gene Expression and Metabolic Traits.

Plos One

P Volkov, AH Olsson, L Gillberg, SW Jørgensen, C Brøns, KF Eriksson, L Groop, PA Jansson, E Nilsson, T Rönn, A Vaag, C Ling

Publication Date: 2016

Variant appearance in text: rs2266788

PubMed Link: 27322064

Variant Present in the following documents:

• pone.0157776.s004.xlsx

View BVdb publication page

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Genetics of Insulin Resistance and the Metabolic Syndrome.

Current Cardiology Reports

AE Brown, M Walker

Publication Date: 2016-08

Variant appearance in text: rs2266788

PubMed Link: 27312935

Variant Present in the following documents:

• Main text

View BVdb publication page

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Distinct Patterns of Association of Variants at 11q23.3 Chromosomal Region with Coronary Artery Disease and Dyslipidemia in the Population of Andhra Pradesh, India.

Plos One

R Pranav Chand, AS Kumar, K Anuj, S Vishnupriya, B Mohan Reddy

Publication Date: 2016

Variant appearance in text: rs2266788

PubMed Link: 27257688

Variant Present in the following documents:

• pone.0153720.s002.docx
• pone.0153720.s003.xlsx

View BVdb publication page

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The Contribution of GWAS Loci in Familial Dyslipidemias.

Plos Genetics

P Ripatti, JT Rämö, S Söderlund, I Surakka, N Matikainen, M Pirinen, P Pajukanta, AP Sarin, SK Service, PP Laurila, C Ehnholm, V Salomaa, RK Wilson, A Palotie, NB Freimer, MR Taskinen, S Ripatti

Publication Date: 2016-05

Variant appearance in text: rs2266788

PubMed Link: 27227539

Variant Present in the following documents:

• pgen.1006078.s008.pdf
• pgen.1006078.s009.pdf

View BVdb publication page

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Nutrigenomics: A controversy.

Applied & Translational Genomics

C Pavlidis, GP Patrinos, T Katsila

Publication Date: 2015-03

Variant appearance in text: rs2266788

PubMed Link: 26937350

Variant Present in the following documents:

• Main text

View BVdb publication page

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Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.

Scientific Reports

JE Below, EJ Parra, ER Gamazon, J Torres, S Krithika, S Candille, Y Lu, A Manichakul, J Peralta-Romero, Q Duan, Y Li, AP Morris, O Gottesman, E Bottinger, XQ Wang, KD Taylor, YD Ida Chen, JI Rotter, SS Rich, RJ Loos, H Tang, NJ Cox, M Cruz, CL Hanis, A Valladares-Salgado

Publication Date: 2016-01-19

Variant appearance in text: rs2266788

PubMed Link: 26780889

Variant Present in the following documents:

• srep19429-s5.xls

View BVdb publication page

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INTEGRATING CLINICAL LABORATORY MEASURES AND ICD-9 CODE DIAGNOSES IN PHENOME-WIDE ASSOCIATION STUDIES.

Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing

A Verma, JB Leader, SS Verma, A Frase, J Wallace, S Dudek, DR Lavage, CV Van Hout, FE Dewey, J Penn, A Lopez, JD Overton, DJ Carey, DH Ledbetter, HL Kirchner, MD Ritchie, SA Pendergrass

Publication Date: 2016

Variant appearance in text: rs2266788

PubMed Link: 26776183

Variant Present in the following documents:

• NIHMS742521-supplement-2.pdf

View BVdb publication page

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Genome-wide association study identifies African-ancestry specific variants for metabolic syndrome.

Molecular Genetics And Metabolism

F Tekola-Ayele, AP Doumatey, D Shriner, AR Bentley, G Chen, J Zhou, O Fasanmade, T Johnson, J Oli, G Okafor, BA Eghan, K Agyenim-Boateng, C Adebamowo, A Amoah, J Acheampong, A Adeyemo, CN Rotimi

Publication Date: 2015-12

Variant appearance in text: rs2266788

PubMed Link: 26507551

Variant Present in the following documents:

• Main text

View BVdb publication page

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Effects of Polymorphisms in APOA4-APOA5-ZNF259-BUD13 Gene Cluster on Plasma Levels of Triglycerides and Risk of Coronary Heart Disease in a Chinese Han Population.

Plos One

Q Fu, X Tang, J Chen, L Su, M Zhang, L Wang, J Jing, L Zhou

Publication Date: 2015

Variant appearance in text: rs2266788

PubMed Link: 26397108

Variant Present in the following documents:

• Main text

View BVdb publication page

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Genetic association of APOA5 and APOE with metabolic syndrome and their interaction with health-related behavior in Korean men.

Lipids In Health And Disease

KY Son, HY Son, J Chae, J Hwang, S Jang, JM Yun, B Cho, JH Park, JI Kim

Publication Date: 2015-09-13

Variant appearance in text: rs2266788

PubMed Link: 26365620

Variant Present in the following documents:

• 12944_2015_111_MOESM1_ESM.docx
• aaaaaMain text

View BVdb publication page

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Positive Association between APOA5 rs662799 Polymorphism and Coronary Heart Disease: A Case-Control Study and Meta-Analysis.

Plos One

H Ye, A Zhou, Q Hong, L Tang, X Xu, Y Xin, D Jiang, D Dai, Y Li, DW Wang, S Duan

Publication Date: 2015

Variant appearance in text: rs2266788

PubMed Link: 26309253

Variant Present in the following documents:

• pone.0135683.s004.doc

View BVdb publication page

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Prediction of Causal Candidate Genes in Coronary Artery Disease Loci.

Arteriosclerosis, Thrombosis, And Vascular Biology

I Brænne, M Civelek, B Vilne, A Di Narzo, AD Johnson, Y Zhao, B Reiz, V Codoni, TR Webb, H Foroughi Asl, SE Hamby, L Zeng, DA Trégouët, K Hao, EJ Topol, EE Schadt, X Yang, NJ Samani, JL Björkegren, J Erdmann, H Schunkert, AJ Lusis,

Publication Date: 2015-10

Variant appearance in text: rs2266788

PubMed Link: 26293461

Variant Present in the following documents:

• Main text
• NIHMS714198-supplement-6.xlsx

View BVdb publication page

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Non-coding genetic variants in human disease.

Human Molecular Genetics

F Zhang, JR Lupski

Publication Date: 2015-10-15

Variant appearance in text: rs2266788

PubMed Link: 26152199

Variant Present in the following documents:

• Main text

View BVdb publication page

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Haplotype analysis of the Apolipoprotein A5 gene in Moroccan patients with the metabolic syndrome.

Journal Of Diabetes And Metabolic Disorders

M Ajjemami, S Ouatou, H Charoute, M Fakiri, H Rhaissi, H Benrahma, H Rouba, A Barakat

Publication Date: 2015

Variant appearance in text: rs2266788

PubMed Link: 25909077

Variant Present in the following documents:

• Main text

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Genome-wide association study of metabolic syndrome in koreans.

Genomics & Informatics

SW Jeong, M Chung, SJ Park, SB Cho, KW Hong

Publication Date: 2014-12

Variant appearance in text: rs2266788

PubMed Link: 25705157

Variant Present in the following documents:

• gni-12-187-s001.pdf

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GWAS-identified loci for coronary heart disease are associated with intima-media thickness and plaque presence at the carotid artery bulb.

Atherosclerosis

M den Hoed, RJ Strawbridge, P Almgren, S Gustafsson, T Axelsson, G Engström, U de Faire, B Hedblad, SE Humphries, CM Lindgren, AP Morris, G Östling, AC Syvänen, E Tremoli, A Hamsten, E Ingelsson, O Melander, L Lind

Publication Date: 2015-04

Variant appearance in text: rs2266788

PubMed Link: 25682028

Variant Present in the following documents:

• NIHMS73492-supplement-Supplement.pdf

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Burden of disease variants in participants of the Long Life Family Study.

Aging

M Stevenson, H Bae, N Schupf, S Andersen, Q Zhang, T Perls, P Sebastiani

Publication Date: 2015-02

Variant appearance in text: rs2266788

PubMed Link: 25664523

Variant Present in the following documents:

• aging-07-0123-s001.docx

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A comparative encyclopedia of DNA elements in the mouse genome.

Nature

F Yue, Y Cheng, A Breschi, J Vierstra, W Wu, T Ryba, R Sandstrom, Z Ma, C Davis, BD Pope, Y Shen, DD Pervouchine, S Djebali, RE Thurman, R Kaul, E Rynes, A Kirilusha, GK Marinov, BA Williams, D Trout, H Amrhein, K Fisher-Aylor, I Antoshechkin, G DeSalvo, LH See, M Fastuca, J Drenkow, C Zaleski, A Dobin, P Prieto, J Lagarde, G Bussotti, A Tanzer, O Denas, K Li, MA Bender, M Zhang, R Byron, MT Groudine, D McCleary, L Pham, Z Ye, S Kuan, L Edsall, YC Wu, MD Rasmussen, MS Bansal, M Kellis, CA Keller, CS Morrissey, T Mishra, D Jain, N Dogan, RS Harris, P Cayting, T Kawli, AP Boyle, G Euskirchen, A Kundaje, S Lin, Y Lin, C Jansen, VS Malladi, MS Cline, DT Erickson, VM Kirkup, K Learned, CA Sloan, KR Rosenbloom, B Lacerda de Sousa, K Beal, M Pignatelli, P Flicek, J Lian, T Kahveci, D Lee, WJ Kent, M Ramalho Santos, J Herrero, C Notredame, A Johnson, S Vong, K Lee, D Bates, F Neri, M Diegel, T Canfield, PJ Sabo, MS Wilken, TA Reh, E Giste, A Shafer, T Kutyavin, E Haugen, D Dunn, AP Reynolds, S Neph, R Humbert, RS Hansen, M De Bruijn, L Selleri, A Rudensky, S Josefowicz, R Samstein, EE Eichler, SH Orkin, D Levasseur, T Papayannopoulou, KH Chang, A Skoultchi, S Gosh, C Disteche, P Treuting, Y Wang, MJ Weiss, GA Blobel, X Cao, S Zhong, T Wang, PJ Good, RF Lowdon, LB Adams, XQ Zhou, MJ Pazin, EA Feingold, B Wold, J Taylor, A Mortazavi, SM Weissman, JA Stamatoyannopoulos, MP Snyder, R Guigo, TR Gingeras, DM Gilbert, RC Hardison, MA Beer, B Ren,

Publication Date: 2014-11-20

Variant appearance in text: rs2266788

PubMed Link: 25409824

Variant Present in the following documents:

• Main text

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Influences of APOA5 variants on plasma triglyceride levels in Uyghur population.

Plos One

S Li, B Hu, Y Wang, D Wu, L Jin, X Wang

Publication Date: 2014

Variant appearance in text: rs2266788

PubMed Link: 25313938

Variant Present in the following documents:

• Main text
• pone.0110258.s001.docx

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Polymorphisms of genes involved in lipid metabolism and risk of chronic kidney disease in Japanese - cross-sectional data from the J-MICC study.

Lipids In Health And Disease

A Hishida, K Wakai, M Naito, S Suma, T Sasakabe, N Hamajima, S Hosono, M Horita, TC Turin, S Suzuki, TS Kairupan, H Mikami, K Ohnaka, I Watanabe, H Uemura, M Kubo, H Tanaka,

Publication Date: 2014-10-14

Variant appearance in text: rs2266788

PubMed Link: 25311932

Variant Present in the following documents:

• 12944_2014_1143_MOESM1_ESM.doc
• aaaaaMain text

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Association between the MLX interacting protein-like, BUD13 homolog and zinc finger protein 259 gene polymorphisms and serum lipid levels.

Scientific Reports

LH Aung, RX Yin, JZ Wu, DF Wu, W Wang, H Li

Publication Date: 2014-07-03

Variant appearance in text: rs2266788

PubMed Link: 24989072

Variant Present in the following documents:

• Main text

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Triglyceride-raising APOA5 genetic variants are associated with obesity and non-HDL-C in Chinese children and adolescents.

Lipids In Health And Disease

WF Zhu, CL Wang, L Liang, Z Shen, JF Fu, PN Liu, LQ Lv, YM Zhu

Publication Date: 2014-06-05

Variant appearance in text: rs2266788

PubMed Link: 24903888

Variant Present in the following documents:

• Main text

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Effects of apolipoprotein A5 haplotypes on the ratio of triglyceride to high-density lipoprotein cholesterol and the risk for metabolic syndrome in Koreans.

Lipids In Health And Disease

S Cha, H Yu, AY Park, KH Song

Publication Date: 2014-03-12

Variant appearance in text: rs2266788

PubMed Link: 24618354

Variant Present in the following documents:

• 1476-511X-13-45-S2.xls
• aaaaaMain text

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Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks.

American Journal Of Human Genetics

GM Peloso, PL Auer, JC Bis, A Voorman, AC Morrison, NO Stitziel, JA Brody, SA Khetarpal, JR Crosby, M Fornage, A Isaacs, J Jakobsdottir, MF Feitosa, G Davies, JE Huffman, A Manichaikul, B Davis, K Lohman, AY Joon, AV Smith, ML Grove, P Zanoni, V Redon, S Demissie, K Lawson, U Peters, C Carlson, RD Jackson, KK Ryckman, RH Mackey, JG Robinson, DS Siscovick, PJ Schreiner, JC Mychaleckyj, JS Pankow, A Hofman, AG Uitterlinden, TB Harris, KD Taylor, JM Stafford, LM Reynolds, RE Marioni, A Dehghan, OH Franco, AP Patel, Y Lu, G Hindy, O Gottesman, EP Bottinger, O Melander, M Orho-Melander, RJ Loos, S Duga, PA Merlini, M Farrall, A Goel, R Asselta, D Girelli, N Martinelli, SH Shah, WE Kraus, M Li, DJ Rader, MP Reilly, R McPherson, H Watkins, D Ardissino, , Q Zhang, J Wang, MY Tsai, HA Taylor, A Correa, ME Griswold, LA Lange, JM Starr, I Rudan, G Eiriksdottir, LJ Launer, JM Ordovas, D Levy, YD Chen, AP Reiner, C Hayward, O Polasek, IJ Deary, IB Borecki, Y Liu, V Gudnason, JG Wilson, CM van Duijn, C Kooperberg, SS Rich, BM Psaty, JI Rotter, CJ O'Donnell, K Rice, E Boerwinkle, S Kathiresan, LA Cupples

Publication Date: 2014-02-06

Variant appearance in text: rs2266788

PubMed Link: 24507774

Variant Present in the following documents:

• Main text

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Re-sequencing expands our understanding of the phenotypic impact of variants at GWAS loci.

Plos Genetics

SK Service, TM Teslovich, C Fuchsberger, V Ramensky, P Yajnik, DC Koboldt, DE Larson, Q Zhang, L Lin, R Welch, L Ding, MD McLellan, M O'Laughlin, C Fronick, LL Fulton, V Magrini, A Swift, P Elliott, MR Jarvelin, M Kaakinen, MI McCarthy, L Peltonen, A Pouta, LL Bonnycastle, FS Collins, N Narisu, HM Stringham, J Tuomilehto, S Ripatti, RS Fulton, C Sabatti, RK Wilson, M Boehnke, NB Freimer

Publication Date: 2014-01

Variant appearance in text: rs2266788

PubMed Link: 24497850

Variant Present in the following documents:

• Main text

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An APOA5 3' UTR variant associated with plasma triglycerides triggers APOA5 downregulation by creating a functional miR-485-5p binding site.

American Journal Of Human Genetics

C Caussy, S Charrière, C Marçais, M Di Filippo, A Sassolas, M Delay, V Euthine, A Jalabert, E Lefai, S Rome, P Moulin

Publication Date: 2014-01-02

Variant appearance in text: rs2266788

PubMed Link: 24387992

Variant Present in the following documents:

• Main text

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Biobanking across the phenome - at the center of chronic disease research.

Bmc Public Health

M Imboden, NM Probst-Hensch

Publication Date: 2013-11-25

Variant appearance in text: rs2266788

PubMed Link: 24274136

Variant Present in the following documents:

• 1471-2458-13-1094-S2.xlsx

View BVdb publication page

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ChIP-seq in steatohepatitis and normal liver tissue identifies candidate disease mechanisms related to progression to cancer.

Bmc Medical Genomics

M Bysani, O Wallerman, S Bornelöv, K Zatloukal, J Komorowski, C Wadelius

Publication Date: 2013-11-08

Variant appearance in text: rs2266788

PubMed Link: 24206787

Variant Present in the following documents:

• 1755-8794-6-50-S2.docx

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Effects of APOA5 -1131T>C (rs662799) on fasting plasma lipids and risk of metabolic syndrome: evidence from a case-control study in China and a meta-analysis.

Plos One

C Xu, R Bai, D Zhang, Z Li, H Zhu, M Lai, Y Zhu

Publication Date: 2013

Variant appearance in text: rs2266788

PubMed Link: 23468858

Variant Present in the following documents:

• Main text

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Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.

Plos One

AG Comuzzie, SA Cole, SL Laston, VS Voruganti, K Haack, RA Gibbs, NF Butte

Publication Date: 2012

Variant appearance in text: rs2266788

PubMed Link: 23251661

Variant Present in the following documents:

• Main text

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Gene-centric meta-analysis of lipid traits in African, East Asian and Hispanic populations.

Plos One

CC Elbers, Y Guo, V Tragante, EP van Iperen, MB Lanktree, BA Castillo, F Chen, LR Yanek, MK Wojczynski, YR Li, B Ferwerda, CM Ballantyne, SG Buxbaum, YD Chen, WM Chen, LA Cupples, M Cushman, Y Duan, D Duggan, MK Evans, JK Fernandes, M Fornage, M Garcia, WT Garvey, N Glazer, F Gomez, TB Harris, I Halder, VJ Howard, MF Keller, MI Kamboh, C Kooperberg, SB Kritchevsky, A LaCroix, K Liu, Y Liu, K Musunuru, AB Newman, NC Onland-Moret, J Ordovas, I Peter, W Post, S Redline, SE Reis, R Saxena, PJ Schreiner, KA Volcik, X Wang, S Yusuf, AB Zonderland, SS Anand, DM Becker, B Psaty, DJ Rader, AP Reiner, SS Rich, JI Rotter, MM Sale, MY Tsai, IB Borecki, RA Hegele, S Kathiresan, MA Nalls, HA Taylor, H Hakonarson, S Sivapalaratnam, FW Asselbergs, F Drenos, JG Wilson, BJ Keating

Publication Date: 2012

Variant appearance in text: rs2266788

PubMed Link: 23236364

Variant Present in the following documents:

• pone.0050198.s002.pdf

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Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

American Journal Of Human Genetics

FW Asselbergs, Y Guo, EP van Iperen, S Sivapalaratnam, V Tragante, MB Lanktree, LA Lange, B Almoguera, YE Appelman, J Barnard, J Baumert, AL Beitelshees, TR Bhangale, YD Chen, TR Gaunt, Y Gong, JC Hopewell, T Johnson, ME Kleber, TY Langaee, M Li, YR Li, K Liu, CW McDonough, MF Meijs, RP Middelberg, K Musunuru, CP Nelson, JR O'Connell, S Padmanabhan, JS Pankow, N Pankratz, S Rafelt, R Rajagopalan, SP Romaine, NJ Schork, J Shaffer, H Shen, EN Smith, SE Tischfield, PJ van der Most, JV van Vliet-Ostaptchouk, N Verweij, KA Volcik, L Zhang, KR Bailey, KM Bailey, F Bauer, JM Boer, PS Braund, A Burt, PR Burton, SG Buxbaum, W Chen, RM Cooper-Dehoff, LA Cupples, JS deJong, C Delles, D Duggan, M Fornage, CE Furlong, N Glazer, JG Gums, C Hastie, MV Holmes, T Illig, SA Kirkland, M Kivimaki, R Klein, BE Klein, C Kooperberg, K Kottke-Marchant, M Kumari, AZ LaCroix, L Mallela, G Murugesan, J Ordovas, WH Ouwehand, WS Post, R Saxena, H Scharnagl, PJ Schreiner, T Shah, DC Shields, D Shimbo, SR Srinivasan, RP Stolk, DI Swerdlow, HA Taylor, EJ Topol, E Toskala, JL van Pelt, J van Setten, S Yusuf, JC Whittaker, AH Zwinderman, , SS Anand, AJ Balmforth, GS Berenson, CR Bezzina, BO Boehm, E Boerwinkle, JP Casas, MJ Caulfield, R Clarke, JM Connell, KJ Cruickshanks, KW Davidson, IN Day, PI de Bakker, PA Doevendans, AF Dominiczak, AS Hall, CA Hartman, C Hengstenberg, HL Hillege, MH Hofker, SE Humphries, GP Jarvik, JA Johnson, BM Kaess, S Kathiresan, W Koenig, DA Lawlor, W März, O Melander, BD Mitchell, GW Montgomery, PB Munroe, SS Murray, SJ Newhouse, NC Onland-Moret, N Poulter, B Psaty, S Redline, SS Rich, JI Rotter, H Schunkert, P Sever, AR Shuldiner, RL Silverstein, A Stanton, B Thorand, MD Trip, MY Tsai, P van der Harst, E van der Schoot, YT van der Schouw, WM Verschuren, H Watkins, AA Wilde, BH Wolffenbuttel, JB Whitfield, GK Hovingh, CM Ballantyne, C Wijmenga, MP Reilly, NG Martin, JG Wilson, DJ Rader, NJ Samani, AP Reiner, RA Hegele, JJ Kastelein, AD Hingorani, PJ Talmud, H Hakonarson, CC Elbers, BJ Keating, F Drenos

Publication Date: 2012-11-02

Variant appearance in text: rs2266788

PubMed Link: 23063622

Variant Present in the following documents:

• mmc4.xls
• mmc7.xls

View BVdb publication page

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Detailed analysis of Japanese population substructure with a focus on the southwest islands of Japan.

Plos One

T Nishiyama, H Kishino, S Suzuki, R Ando, H Niimura, H Uemura, M Horita, K Ohnaka, N Kuriyama, H Mikami, N Takashima, K Mastuo, Y Guang, K Wakai, N Hamajima, H Tanaka,

Publication Date: 2012

Variant appearance in text: rs2266788

PubMed Link: 22509376

Variant Present in the following documents:

• pone.0035000.s006.doc

View BVdb publication page

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Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.

Circulation. Cardiovascular Genetics

K Kristiansson, M Perola, E Tikkanen, J Kettunen, I Surakka, AS Havulinna, A Stancáková, C Barnes, E Widen, E Kajantie, JG Eriksson, J Viikari, M Kähönen, T Lehtimäki, OT Raitakari, AL Hartikainen, A Ruokonen, A Pouta, A Jula, AJ Kangas, P Soininen, M Ala-Korpela, S Männistö, P Jousilahti, LL Bonnycastle, MR Järvelin, J Kuusisto, FS Collins, M Laakso, ME Hurles, A Palotie, L Peltonen, S Ripatti, V Salomaa

Publication Date: 2012-04-01

Variant appearance in text: rs2266788

PubMed Link: 22399527

Variant Present in the following documents:

• NIHMS47601-supplement-supp_data.pdf

View BVdb publication page

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Alternative transcript annotations:

Transcript	cDNA	Protein	Consequence	Exon	Intron
ENST00000227665.4	c.*158C>T	-	3_prime_UTR_variant	3/3	-
ENST00000542499.1	c.*158C>T	-	3_prime_UTR_variant	4/4	-
NM_001166598.2	c.*158C>T	-	3_prime_UTR_variant	4/4	-
NM_001371904.1	c.*158C>T	-	3_prime_UTR_variant	3/3	-
NM_052968.5	c.*158C>T	-	3_prime_UTR_variant	4/4	-