Variant ID: 11-116662579-C-T

NM_001166598.1(APOA5):c.-3G>A

This variant was identified in 100 publications




Publications:


The Gut Microbiota and Inflammation: An Overview.

International Journal Of Environmental Research And Public Health
Z Al Bander, MD Nitert, A Mousa, N Naderpoor
Publication Date: 2020-10-19

Variant appearance in text: rs651821
PubMed Link: 33086688
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association of rs662799 variant and APOA5 gene haplotypes with metabolic syndrome and its components: a meta-analysis in North Africa.

Bioscience Reports
M Hechmi, H Dallali, M Gharbi, H Jmel, M Fassatoui, Y Ben Halima, S Bahri, A Bahlous, A Abid, H Jamoussi, A Barakat, R Kefi
Publication Date: 2020-08-28

Variant appearance in text: rs651821
PubMed Link: 32725151
Variant Present in the following documents:
  • Main text
View BVdb publication page



Blood multiomics reveal insights into population clusters with low prevalence of diabetes, dyslipidemia and hypertension.

Plos One
MW Su, CK Chang, CW Lin, SJ Ling, CN Hsiung, HW Chu, PE Wu, CY Shen
Publication Date: 2020

Variant appearance in text: rs651821
PubMed Link: 32134946
Variant Present in the following documents:
  • Main text
View BVdb publication page



Quantile-dependent expressivity of postprandial lipemia.

Plos One
PT Williams
Publication Date: 2020

Variant appearance in text: rs651821
PubMed Link: 32101585
Variant Present in the following documents:
  • Main text
View BVdb publication page



A comprehensive study of metabolite genetics reveals strong pleiotropy and heterogeneity across time and context.

Nature Communications
A Gallois, J Mefford, A Ko, A Vaysse, H Julienne, M Ala-Korpela, M Laakso, N Zaitlen, P Pajukanta, H Aschard
Publication Date: 2019-10-21

Variant appearance in text: rs651821
PubMed Link: 31636271
Variant Present in the following documents:
  • 41467_2019_12703_MOESM11_ESM.xlsx
  • 41467_2019_12703_MOESM3_ESM.xlsx
  • 41467_2019_12703_MOESM4_ESM.xlsx
  • 41467_2019_12703_MOESM6_ESM.xlsx
  • 41467_2019_12703_MOESM8_ESM.xlsx
View BVdb publication page



Quantitative and Qualitative Role of Antagonistic Heterogeneity in Genetics of Blood Lipids.

The Journals Of Gerontology. Series A, Biological Sciences And Medical Sciences
AM Kulminski, Y Loika, A Nazarian, I Culminskaya
Publication Date: 2020-09-25

Variant appearance in text: rs651821
PubMed Link: 31566214
Variant Present in the following documents:
  • Main text
View BVdb publication page



Exome sequencing of Finnish isolates enhances rare-variant association power.

Nature
AE Locke, KM Steinberg, CWK Chiang, SK Service, AS Havulinna, L Stell, M Pirinen, HJ Abel, CC Chiang, RS Fulton, AU Jackson, CJ Kang, KL Kanchi, DC Koboldt, DE Larson, J Nelson, TJ Nicholas, A Pietilä, V Ramensky, D Ray, LJ Scott, HM Stringham, J Vangipurapu, R Welch, P Yajnik, X Yin, JG Eriksson, M Ala-Korpela, MR Järvelin, M Männikkö, H Laivuori, , SK Dutcher, NO Stitziel, RK Wilson, IM Hall, C Sabatti, A Palotie, V Salomaa, M Laakso, S Ripatti, M Boehnke, NB Freimer
Publication Date: 2019-08

Variant appearance in text: rs651821
PubMed Link: 31367044
Variant Present in the following documents:
  • EMS83607-supplement-Supplementary_Tables.xlsx
View BVdb publication page



Association of BUD13-ZNF259-APOA5-APOA1-SIK3 cluster polymorphism in 11q23.3 and structure of APOA5 with increased plasma triglyceride levels in a Korean population.

Scientific Reports
HK Kim, MA Anwar, S Choi
Publication Date: 2019-06-05

Variant appearance in text: rs651821
PubMed Link: 31165758
Variant Present in the following documents:
  • Main text
View BVdb publication page



Coronary artery disease, genetic risk and the metabolome in young individuals.

Wellcome Open Research
T Battram, L Hoskins, DA Hughes, J Kettunen, SM Ring, G Davey Smith, NJ Timpson
Publication Date: 2018

Variant appearance in text: rs651821
PubMed Link: 30740535
Variant Present in the following documents:
  • Main text
View BVdb publication page



Functional polymorphisms of the APOA1/C3/A4/A5-ZPR1-BUD13 gene cluster are associated with dyslipidemia in a sex-specific pattern.

Peerj
W Bai, C Kou, L Zhang, Y You, W Yu, W Hua, Y Li, Y Yu, T Zhao, Y Wu
Publication Date: 2019

Variant appearance in text: rs651821
PubMed Link: 30631647
Variant Present in the following documents:
  • Main text
  • peerj-07-6175-s001.docx
  • peerj-07-6175-s002.docx
  • peerj-07-6175-s004.docx
View BVdb publication page



Genetic Determinants of Dyslipidemia in African-Based Populations: A Systematic Review.

Omics : A Journal Of Integrative Biology
JJ Noubiap, EPM Mato, M Guewo-Fokeng, AD Kaze, H Boulenouar, A Wonkam
Publication Date: 2018-12

Variant appearance in text: rs651821
PubMed Link: 30571611
Variant Present in the following documents:
  • Main text
View BVdb publication page



Intensive genetic analysis for Chinese patients with very high triglyceride levels: Relations of mutations to triglyceride levels and acute pancreatitis.

Ebiomedicine
JL Jin, D Sun, YX Cao, HW Zhang, YL Guo, NQ Wu, CG Zhu, Y Gao, QT Dong, G Liu, Q Dong, JJ Li
Publication Date: 2018-12

Variant appearance in text: rs651821
PubMed Link: 30420299
Variant Present in the following documents:
  • mmc1.pdf
View BVdb publication page



Global genetic diversity of human apolipoproteins and effects on cardiovascular disease risk.

Journal Of Lipid Research
Y Zhou, R Mägi, L Milani, VM Lauschke
Publication Date: 2018-10

Variant appearance in text: rs651821
PubMed Link: 30076208
Variant Present in the following documents:
  • Main text
View BVdb publication page



Effects of polymorphisms in APOA5 on the plasma levels of triglycerides and risk of coronary heart disease in Jilin, northeast China: a case-control study.

Bmj Open
Y You, YH Wu, Y Zhang, L Zhang, Y Song, W Bai, Y Li, Y Yu, C Kou
Publication Date: 2018-06-04

Variant appearance in text: rs651821
PubMed Link: 29866721
Variant Present in the following documents:
  • Main text
  • bmjopen-2017-020016.draft_revisions.pdf
  • bmjopen-2017-020016.reviewer_comments.pdf
View BVdb publication page



Sequence Analysis of APOA5 Among the Kuwaiti Population Identifies Association of rs2072560, rs2266788, and rs662799 With TG and VLDL Levels.

Frontiers In Genetics
AA Jasim, SA Al-Bustan, W Al-Kandari, A Al-Serri, H AlAskar
Publication Date: 2018

Variant appearance in text: rs651821
PubMed Link: 29686695
Variant Present in the following documents:
  • Main text
  • Table2.pdf
View BVdb publication page



Exome Sequencing Identifies Genetic Variants Associated with Circulating Lipid Levels in Mexican Americans: The Insulin Resistance Atherosclerosis Family Study (IRASFS).

Scientific Reports
C Gao, KL Tabb, LM Dimitrov, KD Taylor, N Wang, X Guo, J Long, JI Rotter, RM Watanabe, JE Curran, J Blangero, CD Langefeld, DW Bowden, ND Palmer
Publication Date: 2018-04-04

Variant appearance in text: rs651821
PubMed Link: 29618726
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic variants in mRNA untranslated regions.

Wiley Interdisciplinary Reviews. Rna
M Steri, ML Idda, MB Whalen, V Orrù
Publication Date: 2018-07

Variant appearance in text: rs651821
PubMed Link: 29582564
Variant Present in the following documents:
  • Main text
View BVdb publication page



Apolipoprotein A5 3'-UTR variants and cardiometabolic traits in Koreans: results from the Korean genome and epidemiology study and the Korea National Health and Nutrition Examination Survey.

Nutrition Research And Practice
OY Kim, J Moon, G Jo, SY Kwak, JY Kim, MJ Shin
Publication Date: 2018-02

Variant appearance in text: rs651821
PubMed Link: 29399298
Variant Present in the following documents:
  • Main text
View BVdb publication page



Identity-by-Descent Mapping Identifies Major Locus for Serum Triglycerides in Amerindians Largely Explained by an APOC3 Founder Mutation.

Circulation. Cardiovascular Genetics
WC Hsueh, AK Nair, S Kobes, P Chen, HHH Göring, TI Pollin, A Malhotra, WC Knowler, LJ Baier, RL Hanson
Publication Date: 2017-12

Variant appearance in text: rs651821
PubMed Link: 29237685
Variant Present in the following documents:
  • Main text
  • NIHMS917321-supplement-001809_-_Supplemental_material.pdf
View BVdb publication page



Detection of susceptibility loci on APOA5 and COLEC12 associated with metabolic syndrome using a genome-wide association study in a Taiwanese population.

Oncotarget
E Lin, PH Kuo, YL Liu, AC Yang, SJ Tsai
Publication Date: 2017-11-07

Variant appearance in text: rs651821
PubMed Link: 29212154
Variant Present in the following documents:
  • Main text
  • oncotarget-08-93349-s002.doc
View BVdb publication page



Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study.

Plos Genetics
JP Davis, JR Huyghe, AE Locke, AU Jackson, X Sim, HM Stringham, TM Teslovich, RP Welch, C Fuchsberger, N Narisu, PS Chines, AJ Kangas, P Soininen, M Ala-Korpela, J Kuusisto, FS Collins, M Laakso, M Boehnke, KL Mohlke
Publication Date: 2017-10

Variant appearance in text: rs651821
PubMed Link: 29084231
Variant Present in the following documents:
  • pgen.1007079.s010.xlsx
View BVdb publication page



Exome chip meta-analysis identifies novel loci and East Asian-specific coding variants that contribute to lipid levels and coronary artery disease.

Nature Genetics
X Lu, GM Peloso, DJ Liu, Y Wu, H Zhang, W Zhou, J Li, CS Tang, R Dorajoo, H Li, J Long, X Guo, M Xu, CN Spracklen, Y Chen, X Liu, Y Zhang, CC Khor, J Liu, L Sun, L Wang, YT Gao, Y Hu, K Yu, Y Wang, CYY Cheung, F Wang, J Huang, Q Fan, Q Cai, S Chen, J Shi, X Yang, W Zhao, WH Sheu, SS Cherny, M He, AB Feranil, LS Adair, P Gordon-Larsen, S Du, R Varma, YI Chen, XO Shu, KSL Lam, TY Wong, SK Ganesh, Z Mo, K Hveem, LG Fritsche, JB Nielsen, HF Tse, Y Huo, CY Cheng, YE Chen, W Zheng, ES Tai, W Gao, X Lin, W Huang, G Abecasis, , S Kathiresan, KL Mohlke, T Wu, PC Sham, D Gu, CJ Willer
Publication Date: 2017-12

Variant appearance in text: rs651821
PubMed Link: 29083407
Variant Present in the following documents:
  • NIHMS909133-supplement-1.docx
  • NIHMS909133-supplement-2.xlsx
View BVdb publication page



Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers.

Plos One
LC Pilling, JL Atkins, MO Duff, RN Beaumont, SE Jones, J Tyrrell, CL Kuo, KS Ruth, MA Tuke, H Yaghootkar, AR Wood, A Murray, MN Weedon, LW Harries, GA Kuchel, L Ferrucci, TM Frayling, D Melzer
Publication Date: 2017

Variant appearance in text: rs651821
PubMed Link: 28957414
Variant Present in the following documents:
  • pone.0185083.s004.xlsx
View BVdb publication page



Association analysis of APO gene polymorphisms with ischemic stroke risk: a case-control study in a Chinese Han population.

Oncotarget
R Xiao, S Sun, J Zhang, Y Ouyang, N Zhang, M Yang, T Jin, Y Xia
Publication Date: 2017-09-01

Variant appearance in text: rs651821
PubMed Link: 28947988
Variant Present in the following documents:
  • Main text
View BVdb publication page



Quantitative trait loci at the 11q23.3 chromosomal region related to dyslipidemia in the population of Andhra Pradesh, India.

Lipids In Health And Disease
R Pranavchand, BM Reddy
Publication Date: 2017-06-13

Variant appearance in text: rs651821
PubMed Link: 28610615
Variant Present in the following documents:
  • 12944_2017_507_MOESM4_ESM.docx
View BVdb publication page



Genetic determinants of inherited susceptibility to hypercholesterolemia - a comprehensive literature review.

Lipids In Health And Disease
CS Paththinige, ND Sirisena, V Dissanayake
Publication Date: 2017-06-02

Variant appearance in text: rs651821
PubMed Link: 28577571
Variant Present in the following documents:
  • 12944_2017_488_MOESM1_ESM.xlsx
View BVdb publication page



Whole genome sequencing and imputation in isolated populations identify genetic associations with medically-relevant complex traits.

Nature Communications
L Southam, A Gilly, D Süveges, AE Farmaki, J Schwartzentruber, I Tachmazidou, A Matchan, NW Rayner, E Tsafantakis, M Karaleftheri, Y Xue, G Dedoussis, E Zeggini
Publication Date: 2017-05-26

Variant appearance in text: rs651821
PubMed Link: 28548082
Variant Present in the following documents:
  • ncomms15606-s1.pdf
View BVdb publication page



Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci.

Human Molecular Genetics
N Zubair, M Graff, J Luis Ambite, WS Bush, G Kichaev, Y Lu, A Manichaikul, WH Sheu, D Absher, TL Assimes, SJ Bielinski, EP Bottinger, P Buzkova, LM Chuang, RH Chung, B Cochran, L Dumitrescu, O Gottesman, JW Haessler, C Haiman, G Heiss, CA Hsiung, YJ Hung, CM Hwu, JJ Juang, L Le Marchand, IT Lee, WJ Lee, LA Lin, D Lin, SY Lin, RH Mackey, LW Martin, B Pasaniuc, U Peters, I Predazzi, T Quertermous, AP Reiner, J Robinson, JI Rotter, KK Ryckman, PJ Schreiner, E Stahl, R Tao, MY Tsai, LL Waite, TD Wang, S Buyske, YD Ida Chen, I Cheng, DC Crawford, RJF Loos, SS Rich, M Fornage, KE North, C Kooperberg, CL Carty
Publication Date: 2016-12-15

Variant appearance in text: rs651821
PubMed Link: 28426890
Variant Present in the following documents:
  • ddw358_supp.docx
View BVdb publication page



Susceptibility loci for metabolic syndrome and metabolic components identified in Han Chinese: a multi-stage genome-wide association study.

Journal Of Cellular And Molecular Medicine
Y Zhu, D Zhang, D Zhou, Z Li, Z Li, L Fang, M Yang, Z Shan, H Li, J Chen, X Zhou, W Ye, S Yu, H Li, L Cai, C Liu, J Zhang, L Wang, Y Lai, L Ruan, Z Sun, S Zhang, H Wang, Y Liu, Y Xu, J Ling, C Xu, Y Zhang, D Lv, Z Yuan, J Zhang, Y Zhang, Y Shi, M Lai
Publication Date: 2017-06

Variant appearance in text: rs651821
PubMed Link: 28371326
Variant Present in the following documents:
  • Main text
  • JCMM-21-1106-s001.docx
View BVdb publication page



Admixture mapping in two Mexican samples identifies significant associations of locus ancestry with triglyceride levels in the BUD13/ZNF259/APOA5 region and fine mapping points to rs964184 as the main driver of the association signal.

Plos One
EJ Parra, A Mazurek, CR Gignoux, A Sockell, M Agostino, AP Morris, LE Petty, CL Hanis, NJ Cox, A Valladares-Salgado, JE Below, M Cruz
Publication Date: 2017

Variant appearance in text: rs651821
PubMed Link: 28245265
Variant Present in the following documents:
  • pone.0172880.s002.xlsx
View BVdb publication page



Associations of triglyceride levels with longevity and frailty: A Mendelian randomization analysis.

Scientific Reports
Z Liu, S Burgess, Z Wang, W Deng, X Chu, J Cai, Y Zhu, J Shi, X Xie, Y Wang, L Jin, X Wang
Publication Date: 2017-01-30

Variant appearance in text: rs651821
PubMed Link: 28134330
Variant Present in the following documents:
  • Main text
View BVdb publication page



Multiphenotype association study of patients randomized to initiate antiretroviral regimens in AIDS Clinical Trials Group protocol A5202.

Pharmacogenetics And Genomics
A Verma, Y Bradford, SS Verma, SA Pendergrass, ES Daar, C Venuto, GD Morse, MD Ritchie, DW Haas
Publication Date: 2017-03

Variant appearance in text: rs651821
PubMed Link: 28099408
Variant Present in the following documents:
  • Main text
View BVdb publication page



Analysis of Whole Exome Sequencing with Cardiometabolic Traits Using Family-Based Linkage and Association in the IRAS Family Study.

Annals Of Human Genetics
KL Tabb, JN Hellwege, ND Palmer, L Dimitrov, S Sajuthi, KD Taylor, MC Ng, GA Hawkins, YI Chen, WM Brown, D McWilliams, A Williams, C Lorenzo, JM Norris, J Long, JI Rotter, JE Curran, J Blangero, LE Wagenknecht, CD Langefeld, DW Bowden
Publication Date: 2017-03

Variant appearance in text: rs651821
PubMed Link: 28067407
Variant Present in the following documents:
  • Main text
View BVdb publication page



Novel genetic loci associated with long-term deterioration in blood lipid concentrations and coronary artery disease in European adults.

International Journal Of Epidemiology
TV Varga, A Kurbasic, M Aine, P Eriksson, A Ali, G Hindy, S Gustafsson, J Luan, D Shungin, Y Chen, CA Schulz, PM Nilsson, G Hallmans, I Barroso, P Deloukas, C Langenberg, RA Scott, NJ Wareham, L Lind, E Ingelsson, O Melander, M Orho-Melander, F Renström, PW Franks
Publication Date: 2017-08-01

Variant appearance in text: rs651821
PubMed Link: 27864399
Variant Present in the following documents:
  • Main text
  • dyw245_supplementary_method_2.docx
  • dyw245_supplementary_table_7.xlsx
  • dyw245_supplementary_table_8.xlsx
  • dyw245_supplementary_table_9.xlsx
View BVdb publication page



Genome-wide compendium and functional assessment of in vivo heart enhancers.

Nature Communications
DE Dickel, I Barozzi, Y Zhu, Y Fukuda-Yuzawa, M Osterwalder, BJ Mannion, D May, CH Spurrell, I Plajzer-Frick, CS Pickle, E Lee, TH Garvin, M Kato, JA Akiyama, V Afzal, AY Lee, DU Gorkin, B Ren, EM Rubin, A Visel, LA Pennacchio
Publication Date: 2016-10-05

Variant appearance in text: rs651821
PubMed Link: 27703156
Variant Present in the following documents:
  • ncomms12923-s2.xlsx
View BVdb publication page



Single Nucleotide Polymorphisms in Cellular Drug Transporters Are Associated with Intolerance to Antiretroviral Therapy in Brazilian HIV-1 Positive Individuals.

Plos One
MB Arruda, F Campagnari, TB de Almeida, JC Couto-Fernandez, A Tanuri, CC Cardoso
Publication Date: 2016

Variant appearance in text: rs651821
PubMed Link: 27648838
Variant Present in the following documents:
  • pone.0163170.s001.xlsx
View BVdb publication page



A Genome-Wide mQTL Analysis in Human Adipose Tissue Identifies Genetic Variants Associated with DNA Methylation, Gene Expression and Metabolic Traits.

Plos One
P Volkov, AH Olsson, L Gillberg, SW Jørgensen, C Brøns, KF Eriksson, L Groop, PA Jansson, E Nilsson, T Rönn, A Vaag, C Ling
Publication Date: 2016

Variant appearance in text: rs651821
PubMed Link: 27322064
Variant Present in the following documents:
  • pone.0157776.s004.xlsx
View BVdb publication page



Distinct Patterns of Association of Variants at 11q23.3 Chromosomal Region with Coronary Artery Disease and Dyslipidemia in the Population of Andhra Pradesh, India.

Plos One
R Pranav Chand, AS Kumar, K Anuj, S Vishnupriya, B Mohan Reddy
Publication Date: 2016

Variant appearance in text: rs651821
PubMed Link: 27257688
Variant Present in the following documents:
  • Main text
  • pone.0153720.s002.docx
  • pone.0153720.s003.xlsx
  • pone.0153720.s005.docx
View BVdb publication page



The Contribution of GWAS Loci in Familial Dyslipidemias.

Plos Genetics
P Ripatti, JT Rämö, S Söderlund, I Surakka, N Matikainen, M Pirinen, P Pajukanta, AP Sarin, SK Service, PP Laurila, C Ehnholm, V Salomaa, RK Wilson, A Palotie, NB Freimer, MR Taskinen, S Ripatti
Publication Date: 2016-05

Variant appearance in text: rs651821
PubMed Link: 27227539
Variant Present in the following documents:
  • pgen.1006078.s008.pdf
  • pgen.1006078.s009.pdf
View BVdb publication page



Meta-analysis of genome-wide association studies identifies three novel loci for saturated fatty acids in East Asians.

European Journal Of Nutrition
J Zhu, A Manichaikul, Y Hu, YI Chen, S Liang, LM Steffen, SS Rich, M Tsai, DS Siscovick, RN Lemaitre, H Li, X Lin
Publication Date: 2017-06

Variant appearance in text: rs651821
PubMed Link: 26932504
Variant Present in the following documents:
  • Main text
  • NIHMS846187-supplement-1.pdf
View BVdb publication page



Interactions of Environmental Factors and APOA1-APOC3-APOA4-APOA5 Gene Cluster Gene Polymorphisms with Metabolic Syndrome.

Plos One
Y Wu, Y Yu, T Zhao, S Wang, Y Fu, Y Qi, G Yang, W Yao, Y Su, Y Ma, J Shi, J Jiang, C Kou
Publication Date: 2016

Variant appearance in text: rs651821
PubMed Link: 26824674
Variant Present in the following documents:
  • Main text
View BVdb publication page



INTEGRATING CLINICAL LABORATORY MEASURES AND ICD-9 CODE DIAGNOSES IN PHENOME-WIDE ASSOCIATION STUDIES.

Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing
A Verma, JB Leader, SS Verma, A Frase, J Wallace, S Dudek, DR Lavage, CV Van Hout, FE Dewey, J Penn, A Lopez, JD Overton, DJ Carey, DH Ledbetter, HL Kirchner, MD Ritchie, SA Pendergrass
Publication Date: 2016

Variant appearance in text: rs651821
PubMed Link: 26776183
Variant Present in the following documents:
  • NIHMS742521-supplement-2.pdf
View BVdb publication page



Exome-wide association analysis reveals novel coding sequence variants associated with lipid traits in Chinese.

Nature Communications
CS Tang, H Zhang, CY Cheung, M Xu, JC Ho, W Zhou, SS Cherny, Y Zhang, O Holmen, KW Au, H Yu, L Xu, J Jia, RM Porsch, L Sun, W Xu, H Zheng, LY Wong, Y Mu, J Dou, CH Fong, S Wang, X Hong, L Dong, Y Liao, J Wang, LS Lam, X Su, H Yan, ML Yang, J Chen, CW Siu, G Xie, YC Woo, Y Wu, KC Tan, K Hveem, BM Cheung, S Zöllner, A Xu, Y Eugene Chen, CQ Jiang, Y Zhang, TH Lam, SK Ganesh, Y Huo, PC Sham, KS Lam, CJ Willer, HF Tse, W Gao
Publication Date: 2015-12-22

Variant appearance in text: rs651821
PubMed Link: 26690388
Variant Present in the following documents:
  • Main text
  • ncomms10206-s1.pdf
  • ncomms10206-s2.xlsx
View BVdb publication page



Multiple susceptibility loci at chromosome 11q23.3 are associated with plasma triglyceride in East Asians.

Journal Of Lipid Research
B Gombojav, SJ Lee, M Kho, YM Song, K Lee, J Sung
Publication Date: 2016-02

Variant appearance in text: rs651821
PubMed Link: 26634697
Variant Present in the following documents:
  • Main text
View BVdb publication page



The epigenomic landscape of African rainforest hunter-gatherers and farmers.

Nature Communications
M Fagny, E Patin, JL MacIsaac, M Rotival, T Flutre, MJ Jones, KJ Siddle, H Quach, C Harmant, LM McEwen, A Froment, E Heyer, A Gessain, E Betsem, P Mouguiama-Daouda, JM Hombert, GH Perry, LB Barreiro, MS Kobor, L Quintana-Murci
Publication Date: 2015-11-30

Variant appearance in text: rs651821
PubMed Link: 26616214
Variant Present in the following documents:
  • ncomms10047-s2.xlsx
View BVdb publication page



Discovery of phenotypic networks from genotypic association studies with application to obesity.

International Journal Of Data Mining And Bioinformatics
CW Duarte, YC Klimentidis, JJ Harris, M Cardel, JR Fernández
Publication Date: 2015

Variant appearance in text: rs651821
PubMed Link: 26510299
Variant Present in the following documents:
  • NIHMS738263-supplement-Supplemental_tables.docx
View BVdb publication page



Effects of Polymorphisms in APOA4-APOA5-ZNF259-BUD13 Gene Cluster on Plasma Levels of Triglycerides and Risk of Coronary Heart Disease in a Chinese Han Population.

Plos One
Q Fu, X Tang, J Chen, L Su, M Zhang, L Wang, J Jing, L Zhou
Publication Date: 2015

Variant appearance in text: rs651821
PubMed Link: 26397108
Variant Present in the following documents:
  • Main text
  • pone.0138652.s001.doc
View BVdb publication page



Positive Association between APOA5 rs662799 Polymorphism and Coronary Heart Disease: A Case-Control Study and Meta-Analysis.

Plos One
H Ye, A Zhou, Q Hong, L Tang, X Xu, Y Xin, D Jiang, D Dai, Y Li, DW Wang, S Duan
Publication Date: 2015

Variant appearance in text: rs651821
PubMed Link: 26309253
Variant Present in the following documents:
  • pone.0135683.s004.doc
View BVdb publication page



Evaluation of transethnic fine mapping with population-specific and cosmopolitan imputation reference panels in diverse Asian populations.

European Journal Of Human Genetics : Ejhg
X Wang, CY Cheng, J Liao, X Sim, J Liu, KS Chia, ES Tai, P Little, CC Khor, T Aung, TY Wong, YY Teo
Publication Date: 2016-04

Variant appearance in text: rs651821
PubMed Link: 26130488
Variant Present in the following documents:
  • ejhg2015150x4.xls
  • ejhg2015150x5.doc
View BVdb publication page



Family-based association analysis: a fast and efficient method of multivariate association analysis with multiple variants.

Bmc Bioinformatics
S Won, W Kim, S Lee, Y Lee, J Sung, T Park
Publication Date: 2015-02-15

Variant appearance in text: rs651821
PubMed Link: 25887481
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genome-wide association study of metabolic syndrome in koreans.

Genomics & Informatics
SW Jeong, M Chung, SJ Park, SB Cho, KW Hong
Publication Date: 2014-12

Variant appearance in text: rs651821
PubMed Link: 25705157
Variant Present in the following documents:
  • Main text
  • gni-12-187-s001.pdf
View BVdb publication page



Integromic analysis of genetic variation and gene expression identifies networks for cardiovascular disease phenotypes.

Circulation
C Yao, BH Chen, R Joehanes, B Otlu, X Zhang, C Liu, T Huan, O Tastan, LA Cupples, JB Meigs, CS Fox, JE Freedman, P Courchesne, CJ O'Donnell, PJ Munson, S Keles, D Levy
Publication Date: 2015-02-10

Variant appearance in text: rs651821
PubMed Link: 25533967
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association between Expression Quantitative Trait Loci and Metabolic Traits in Two Korean Populations.

Plos One
KW Hong, SW Jeong, M Chung, SB Cho
Publication Date: 2014

Variant appearance in text: rs651821
PubMed Link: 25493549
Variant Present in the following documents:
  • Main text
  • pone.0114128.s002.xlsx
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Influences of APOA5 variants on plasma triglyceride levels in Uyghur population.

Plos One
S Li, B Hu, Y Wang, D Wu, L Jin, X Wang
Publication Date: 2014

Variant appearance in text: rs651821
PubMed Link: 25313938
Variant Present in the following documents:
  • Main text
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Association between the MLX interacting protein-like, BUD13 homolog and zinc finger protein 259 gene polymorphisms and serum lipid levels.

Scientific Reports
LH Aung, RX Yin, JZ Wu, DF Wu, W Wang, H Li
Publication Date: 2014-07-03

Variant appearance in text: rs651821
PubMed Link: 24989072
Variant Present in the following documents:
  • Main text
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Genomic and metabolomic profile associated to microalbuminuria.

Plos One
VG Marrachelli, D Monleon, P Rentero, ML Mansego, JM Morales, I Galan, R Segura, F Martinez, JC Martin-Escudero, L Briongos, P Marin, G Lliso, FJ Chaves, J Redon
Publication Date: 2014

Variant appearance in text: rs651821
PubMed Link: 24918908
Variant Present in the following documents:
  • Main text
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Triglyceride-raising APOA5 genetic variants are associated with obesity and non-HDL-C in Chinese children and adolescents.

Lipids In Health And Disease
WF Zhu, CL Wang, L Liang, Z Shen, JF Fu, PN Liu, LQ Lv, YM Zhu
Publication Date: 2014-06-05

Variant appearance in text: rs651821
PubMed Link: 24903888
Variant Present in the following documents:
  • Main text
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Analysis of common and coding variants with cardiovascular disease in the Diabetes Heart Study.

Cardiovascular Diabetology
JN Adams, LM Raffield, BI Freedman, CD Langefeld, MC Ng, JJ Carr, AJ Cox, DW Bowden
Publication Date: 2014-04-12

Variant appearance in text: rs651821
PubMed Link: 24725463
Variant Present in the following documents:
  • 1475-2840-13-77-S1.xls
  • aaaaaMain text
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Effects of apolipoprotein A5 haplotypes on the ratio of triglyceride to high-density lipoprotein cholesterol and the risk for metabolic syndrome in Koreans.

Lipids In Health And Disease
S Cha, H Yu, AY Park, KH Song
Publication Date: 2014-03-12

Variant appearance in text: rs651821
PubMed Link: 24618354
Variant Present in the following documents:
  • 1476-511X-13-45-S2.xls
  • aaaaaMain text
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Re-sequencing expands our understanding of the phenotypic impact of variants at GWAS loci.

Plos Genetics
SK Service, TM Teslovich, C Fuchsberger, V Ramensky, P Yajnik, DC Koboldt, DE Larson, Q Zhang, L Lin, R Welch, L Ding, MD McLellan, M O'Laughlin, C Fronick, LL Fulton, V Magrini, A Swift, P Elliott, MR Jarvelin, M Kaakinen, MI McCarthy, L Peltonen, A Pouta, LL Bonnycastle, FS Collins, N Narisu, HM Stringham, J Tuomilehto, S Ripatti, RS Fulton, C Sabatti, RK Wilson, M Boehnke, NB Freimer
Publication Date: 2014-01

Variant appearance in text: rs651821
PubMed Link: 24497850
Variant Present in the following documents:
  • Main text
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An APOA5 3' UTR variant associated with plasma triglycerides triggers APOA5 downregulation by creating a functional miR-485-5p binding site.

American Journal Of Human Genetics
C Caussy, S Charrière, C Marçais, M Di Filippo, A Sassolas, M Delay, V Euthine, A Jalabert, E Lefai, S Rome, P Moulin
Publication Date: 2014-01-02

Variant appearance in text: rs651821
PubMed Link: 24387992
Variant Present in the following documents:
  • Main text
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A genome wide association study identifies common variants associated with lipid levels in the Chinese population.

Plos One
L Zhou, M He, Z Mo, C Wu, H Yang, D Yu, X Yang, X Zhang, Y Wang, J Sun, Y Gao, A Tan, Y He, H Zhang, X Qin, J Zhu, H Li, X Lin, J Zhu, X Min, M Lang, D Li, K Zhai, J Chang, W Tan, J Yuan, W Chen, Y Wang, S Wei, X Miao, F Wang, W Fang, Y Liang, Q Deng, X Dai, D Lin, S Huang, H Guo, S Lilly Zheng, J Xu, D Lin, FB Hu, T Wu
Publication Date: 2013

Variant appearance in text: rs651821
PubMed Link: 24386095
Variant Present in the following documents:
  • Main text
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Biobanking across the phenome - at the center of chronic disease research.

Bmc Public Health
M Imboden, NM Probst-Hensch
Publication Date: 2013-11-25

Variant appearance in text: rs651821
PubMed Link: 24274136
Variant Present in the following documents:
  • 1471-2458-13-1094-S2.xlsx
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ChIP-seq in steatohepatitis and normal liver tissue identifies candidate disease mechanisms related to progression to cancer.

Bmc Medical Genomics
M Bysani, O Wallerman, S Bornelöv, K Zatloukal, J Komorowski, C Wadelius
Publication Date: 2013-11-08

Variant appearance in text: rs651821
PubMed Link: 24206787
Variant Present in the following documents:
  • 1755-8794-6-50-S2.docx
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Gene-centric association signals for haemostasis and thrombosis traits identified with the HumanCVD BeadChip.

Thrombosis And Haemostasis
TR Gaunt, D Zabaneh, S Shah, A Guyatt, C Ladroue, M Kumari, F Drenos, T Shah, PJ Talmud, JP Casas, G Lowe, A Rumley, DA Lawlor, M Kivimaki, J Whittaker, AD Hingorani, SE Humphries, IN Day
Publication Date: 2013-11

Variant appearance in text: rs651821
PubMed Link: 24178511
Variant Present in the following documents:
  • Main text
  • NIHMS58613-supplement-Supplementary_Data.doc
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Discovery and refinement of loci associated with lipid levels.

Nature Genetics
CJ Willer, EM Schmidt, S Sengupta, GM Peloso, S Gustafsson, S Kanoni, A Ganna, J Chen, ML Buchkovich, S Mora, JS Beckmann, JL Bragg-Gresham, HY Chang, A Demirkan, HM Den Hertog, R Do, LA Donnelly, GB Ehret, T Esko, MF Feitosa, T Ferreira, K Fischer, P Fontanillas, RM Fraser, DF Freitag, D Gurdasani, K Heikkilä, E Hyppönen, A Isaacs, AU Jackson, Å Johansson, T Johnson, M Kaakinen, J Kettunen, ME Kleber, X Li, J Luan, LP Lyytikäinen, PKE Magnusson, M Mangino, E Mihailov, ME Montasser, M Müller-Nurasyid, IM Nolte, JR O'Connell, CD Palmer, M Perola, AK Petersen, S Sanna, R Saxena, SK Service, S Shah, D Shungin, C Sidore, C Song, RJ Strawbridge, I Surakka, T Tanaka, TM Teslovich, G Thorleifsson, EG Van den Herik, BF Voight, KA Volcik, LL Waite, A Wong, Y Wu, W Zhang, D Absher, G Asiki, I Barroso, LF Been, JL Bolton, LL Bonnycastle, P Brambilla, MS Burnett, G Cesana, M Dimitriou, ASF Doney, A Döring, P Elliott, SE Epstein, G Ingi Eyjolfsson, B Gigante, MO Goodarzi, H Grallert, ML Gravito, CJ Groves, G Hallmans, AL Hartikainen, C Hayward, D Hernandez, AA Hicks, H Holm, YJ Hung, T Illig, MR Jones, P Kaleebu, JJP Kastelein, KT Khaw, E Kim, N Klopp, P Komulainen, M Kumari, C Langenberg, T Lehtimäki, SY Lin, J Lindström, RJF Loos, F Mach, WL McArdle, C Meisinger, BD Mitchell, G Müller, R Nagaraja, N Narisu, TVM Nieminen, RN Nsubuga, I Olafsson, KK Ong, A Palotie, T Papamarkou, C Pomilla, A Pouta, DJ Rader, MP Reilly, PM Ridker, F Rivadeneira, I Rudan, A Ruokonen, N Samani, H Scharnagl, J Seeley, K Silander, A Stančáková, K Stirrups, AJ Swift, L Tiret, AG Uitterlinden, LJ van Pelt, S Vedantam, N Wainwright, C Wijmenga, SH Wild, G Willemsen, T Wilsgaard, JF Wilson, EH Young, JH Zhao, LS Adair, D Arveiler, TL Assimes, S Bandinelli, F Bennett, M Bochud, BO Boehm, DI Boomsma, IB Borecki, SR Bornstein, P Bovet, M Burnier, H Campbell, A Chakravarti, JC Chambers, YI Chen, FS Collins, RS Cooper, J Danesh, G Dedoussis, U de Faire, AB Feranil, J Ferrières, L Ferrucci, NB Freimer, C Gieger, LC Groop, V Gudnason, U Gyllensten, A Hamsten, TB Harris, A Hingorani, JN Hirschhorn, A Hofman, GK Hovingh, CA Hsiung, SE Humphries, SC Hunt, K Hveem, C Iribarren, MR Järvelin, A Jula, M Kähönen, J Kaprio, A Kesäniemi, M Kivimaki, JS Kooner, PJ Koudstaal, RM Krauss, D Kuh, J Kuusisto, KO Kyvik, M Laakso, TA Lakka, L Lind, CM Lindgren, NG Martin, W März, MI McCarthy, CA McKenzie, P Meneton, A Metspalu, L Moilanen, AD Morris, PB Munroe, I Njølstad, NL Pedersen, C Power, PP Pramstaller, JF Price, BM Psaty, T Quertermous, R Rauramaa, D Saleheen, V Salomaa, DK Sanghera, J Saramies, PEH Schwarz, WH Sheu, AR Shuldiner, A Siegbahn, TD Spector, K Stefansson, DP Strachan, BO Tayo, E Tremoli, J Tuomilehto, M Uusitupa, CM van Duijn, P Vollenweider, L Wallentin, NJ Wareham, JB Whitfield, BHR Wolffenbuttel, JM Ordovas, E Boerwinkle, CNA Palmer, U Thorsteinsdottir, DI Chasman, JI Rotter, PW Franks, S Ripatti, LA Cupples, MS Sandhu, SS Rich, M Boehnke, P Deloukas, S Kathiresan, KL Mohlke, E Ingelsson, GR Abecasis,
Publication Date: 2013-11

Variant appearance in text: rs651821
PubMed Link: 24097068
Variant Present in the following documents:
  • NIHMS524703-supplement-1.pdf
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Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels.

Journal Of Lipid Research
Y Wu, AF Marvelle, J Li, DC Croteau-Chonka, AB Feranil, CW Kuzawa, Y Li, LS Adair, KL Mohlke
Publication Date: 2013-11

Variant appearance in text: rs651821
PubMed Link: 24023260
Variant Present in the following documents:
  • Main text
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Properties of local interactions and their potential value in complementing genome-wide association studies.

Plos One
W Wei, A Gyenesei, CA Semple, CS Haley
Publication Date: 2013

Variant appearance in text: rs651821
PubMed Link: 23940718
Variant Present in the following documents:
  • pone.0071203.s003.xlsx
View BVdb publication page



Alternative transcript annotations:

Transcript cDNA Protein Consequence Exon Intron
ENST00000227665.4 c.-3G>A - 5_prime_UTR_variant 1/3 -
ENST00000433069.1 c.-3G>A - 5_prime_UTR_variant 2/4 -
ENST00000542499.1 c.-3G>A - 5_prime_UTR_variant 2/4 -
NM_001166598.2 c.-3G>A - 5_prime_UTR_variant 2/4 -
NM_001371904.1 c.-3G>A - 5_prime_UTR_variant 1/3 -
NM_052968.5 c.-3G>A - 5_prime_UTR_variant 2/4 -