Variant ID: 11-116707583-A-G

NM_000039.1(APOA1):c.200+134T>C

This variant was identified in 16 publications




Publications:


Association of Apolipoprotein e2 Allele with Insulin Resistance and Risk of Type 2 Diabetes Mellitus Among an Admixed Population of Mexico.

Diabetes, Metabolic Syndrome And Obesity : Targets And Therapy
K Gonzalez-Aldaco, S Roman, LA Torres-Reyes, A Panduro
Publication Date: 2020

Variant appearance in text: rs5072
PubMed Link: 33116704
Variant Present in the following documents:
  • Main text
View BVdb publication page



Influence of multiple apolipoprotein A-I and B genetic variations on insulin resistance and metabolic syndrome in obstructive sleep apnea.

Nutrition & Metabolism
X Li, Z Fu, H Xu, J Zou, H Zhu, Z Li, K Su, Huai, H Yi, J Guan, S Yin
Publication Date: 2020

Variant appearance in text: rs5072
PubMed Link: 33005209
Variant Present in the following documents:
  • Main text
View BVdb publication page



Functional polymorphisms of the APOA1/C3/A4/A5-ZPR1-BUD13 gene cluster are associated with dyslipidemia in a sex-specific pattern.

Peerj
W Bai, C Kou, L Zhang, Y You, W Yu, W Hua, Y Li, Y Yu, T Zhao, Y Wu
Publication Date: 2019

Variant appearance in text: rs5072
PubMed Link: 30631647
Variant Present in the following documents:
  • Main text
  • peerj-07-6175-s001.docx
  • peerj-07-6175-s002.docx
  • peerj-07-6175-s004.docx
View BVdb publication page



Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study.

Plos Genetics
JP Davis, JR Huyghe, AE Locke, AU Jackson, X Sim, HM Stringham, TM Teslovich, RP Welch, C Fuchsberger, N Narisu, PS Chines, AJ Kangas, P Soininen, M Ala-Korpela, J Kuusisto, FS Collins, M Laakso, M Boehnke, KL Mohlke
Publication Date: 2017-10

Variant appearance in text: rs5072
PubMed Link: 29084231
Variant Present in the following documents:
  • pgen.1007079.s010.xlsx
View BVdb publication page



Interactions of six SNPs in APOA1 gene and types of obesity on low HDL-C disease in Xinjiang pastoral area of China.

Lipids In Health And Disease
X Wang, J He, H Guo, L Mu, Y Hu, J Ma, Y Yan, R Ma, S Li, Y Ding, M Zhang, Q Niu, J Liu, J Zhang, S Guo
Publication Date: 2017-10-02

Variant appearance in text: rs5072
PubMed Link: 28969676
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association analysis of APO gene polymorphisms with ischemic stroke risk: a case-control study in a Chinese Han population.

Oncotarget
R Xiao, S Sun, J Zhang, Y Ouyang, N Zhang, M Yang, T Jin, Y Xia
Publication Date: 2017-09-01

Variant appearance in text: rs5072
PubMed Link: 28947988
Variant Present in the following documents:
  • Main text
View BVdb publication page



Quantitative trait loci at the 11q23.3 chromosomal region related to dyslipidemia in the population of Andhra Pradesh, India.

Lipids In Health And Disease
R Pranavchand, BM Reddy
Publication Date: 2017-06-13

Variant appearance in text: rs5072
PubMed Link: 28610615
Variant Present in the following documents:
  • 12944_2017_507_MOESM2_ESM.docx
  • 12944_2017_507_MOESM3_ESM.docx
  • 12944_2017_507_MOESM4_ESM.docx
  • aaaaaMain text
View BVdb publication page



Genetic determinants of clinical heterogeneity of the coronary artery disease in the population of Hyderabad, India.

Human Genomics
R Pranavchand, AS Kumar, BM Reddy
Publication Date: 2017-03-04

Variant appearance in text: rs5072
PubMed Link: 28257648
Variant Present in the following documents:
  • 40246_2017_99_MOESM3_ESM.docx
  • aaaaaMain text
View BVdb publication page



Distinct Patterns of Association of Variants at 11q23.3 Chromosomal Region with Coronary Artery Disease and Dyslipidemia in the Population of Andhra Pradesh, India.

Plos One
R Pranav Chand, AS Kumar, K Anuj, S Vishnupriya, B Mohan Reddy
Publication Date: 2016

Variant appearance in text: rs5072
PubMed Link: 27257688
Variant Present in the following documents:
  • Main text
  • pone.0153720.s002.docx
  • pone.0153720.s003.xlsx
View BVdb publication page



Interactions of Environmental Factors and APOA1-APOC3-APOA4-APOA5 Gene Cluster Gene Polymorphisms with Metabolic Syndrome.

Plos One
Y Wu, Y Yu, T Zhao, S Wang, Y Fu, Y Qi, G Yang, W Yao, Y Su, Y Ma, J Shi, J Jiang, C Kou
Publication Date: 2016

Variant appearance in text: rs5072
PubMed Link: 26824674
Variant Present in the following documents:
  • Main text
View BVdb publication page



Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.

Scientific Reports
JE Below, EJ Parra, ER Gamazon, J Torres, S Krithika, S Candille, Y Lu, A Manichakul, J Peralta-Romero, Q Duan, Y Li, AP Morris, O Gottesman, E Bottinger, XQ Wang, KD Taylor, YD Ida Chen, JI Rotter, SS Rich, RJ Loos, H Tang, NJ Cox, M Cruz, CL Hanis, A Valladares-Salgado
Publication Date: 2016-01-19

Variant appearance in text: rs5072
PubMed Link: 26780889
Variant Present in the following documents:
  • srep19429-s3.xls
View BVdb publication page



Genetics of kidney disease and related cardiometabolic phenotypes in Zuni Indians: the Zuni Kidney Project.

Frontiers In Genetics
SL Laston, VS Voruganti, K Haack, VO Shah, A Bobelu, J Bobelu, D Ghahate, AM Harford, SS Paine, F Tentori, SA Cole, JW MacCluer, AG Comuzzie, PG Zager
Publication Date: 2015

Variant appearance in text: rs5072
PubMed Link: 25688259
Variant Present in the following documents:
  • Main text
View BVdb publication page



Gene-centric association signals for haemostasis and thrombosis traits identified with the HumanCVD BeadChip.

Thrombosis And Haemostasis
TR Gaunt, D Zabaneh, S Shah, A Guyatt, C Ladroue, M Kumari, F Drenos, T Shah, PJ Talmud, JP Casas, G Lowe, A Rumley, DA Lawlor, M Kivimaki, J Whittaker, AD Hingorani, SE Humphries, IN Day
Publication Date: 2013-11

Variant appearance in text: rs5072
PubMed Link: 24178511
Variant Present in the following documents:
  • Main text
View BVdb publication page



Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

American Journal Of Human Genetics
FW Asselbergs, Y Guo, EP van Iperen, S Sivapalaratnam, V Tragante, MB Lanktree, LA Lange, B Almoguera, YE Appelman, J Barnard, J Baumert, AL Beitelshees, TR Bhangale, YD Chen, TR Gaunt, Y Gong, JC Hopewell, T Johnson, ME Kleber, TY Langaee, M Li, YR Li, K Liu, CW McDonough, MF Meijs, RP Middelberg, K Musunuru, CP Nelson, JR O'Connell, S Padmanabhan, JS Pankow, N Pankratz, S Rafelt, R Rajagopalan, SP Romaine, NJ Schork, J Shaffer, H Shen, EN Smith, SE Tischfield, PJ van der Most, JV van Vliet-Ostaptchouk, N Verweij, KA Volcik, L Zhang, KR Bailey, KM Bailey, F Bauer, JM Boer, PS Braund, A Burt, PR Burton, SG Buxbaum, W Chen, RM Cooper-Dehoff, LA Cupples, JS deJong, C Delles, D Duggan, M Fornage, CE Furlong, N Glazer, JG Gums, C Hastie, MV Holmes, T Illig, SA Kirkland, M Kivimaki, R Klein, BE Klein, C Kooperberg, K Kottke-Marchant, M Kumari, AZ LaCroix, L Mallela, G Murugesan, J Ordovas, WH Ouwehand, WS Post, R Saxena, H Scharnagl, PJ Schreiner, T Shah, DC Shields, D Shimbo, SR Srinivasan, RP Stolk, DI Swerdlow, HA Taylor, EJ Topol, E Toskala, JL van Pelt, J van Setten, S Yusuf, JC Whittaker, AH Zwinderman, , SS Anand, AJ Balmforth, GS Berenson, CR Bezzina, BO Boehm, E Boerwinkle, JP Casas, MJ Caulfield, R Clarke, JM Connell, KJ Cruickshanks, KW Davidson, IN Day, PI de Bakker, PA Doevendans, AF Dominiczak, AS Hall, CA Hartman, C Hengstenberg, HL Hillege, MH Hofker, SE Humphries, GP Jarvik, JA Johnson, BM Kaess, S Kathiresan, W Koenig, DA Lawlor, W März, O Melander, BD Mitchell, GW Montgomery, PB Munroe, SS Murray, SJ Newhouse, NC Onland-Moret, N Poulter, B Psaty, S Redline, SS Rich, JI Rotter, H Schunkert, P Sever, AR Shuldiner, RL Silverstein, A Stanton, B Thorand, MD Trip, MY Tsai, P van der Harst, E van der Schoot, YT van der Schouw, WM Verschuren, H Watkins, AA Wilde, BH Wolffenbuttel, JB Whitfield, GK Hovingh, CM Ballantyne, C Wijmenga, MP Reilly, NG Martin, JG Wilson, DJ Rader, NJ Samani, AP Reiner, RA Hegele, JJ Kastelein, AD Hingorani, PJ Talmud, H Hakonarson, CC Elbers, BJ Keating, F Drenos
Publication Date: 2012-11-02

Variant appearance in text: rs5072
PubMed Link: 23063622
Variant Present in the following documents:
  • mmc4.xls
  • mmc7.xls
  • mmc9.xls
View BVdb publication page



Genome-wide association study identifies multiple loci influencing human serum metabolite levels.

Nature Genetics
J Kettunen, T Tukiainen, AP Sarin, A Ortega-Alonso, E Tikkanen, LP Lyytikäinen, AJ Kangas, P Soininen, P Würtz, K Silander, DM Dick, RJ Rose, MJ Savolainen, J Viikari, M Kähönen, T Lehtimäki, KH Pietiläinen, M Inouye, MI McCarthy, A Jula, J Eriksson, OT Raitakari, V Salomaa, J Kaprio, MR Järvelin, L Peltonen, M Perola, NB Freimer, M Ala-Korpela, A Palotie, S Ripatti
Publication Date: 2012-01-29

Variant appearance in text: rs5072
PubMed Link: 22286219
Variant Present in the following documents:
  • NIHMS444574-supplement-supplementary_table_2.xlsx
View BVdb publication page



Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.

American Journal Of Human Genetics
PJ Talmud, F Drenos, S Shah, T Shah, J Palmen, C Verzilli, TR Gaunt, J Pallas, R Lovering, K Li, JP Casas, R Sofat, M Kumari, S Rodriguez, T Johnson, SJ Newhouse, A Dominiczak, NJ Samani, M Caulfield, P Sever, A Stanton, DC Shields, S Padmanabhan, O Melander, C Hastie, C Delles, S Ebrahim, MG Marmot, GD Smith, DA Lawlor, PB Munroe, IN Day, M Kivimaki, J Whittaker, SE Humphries, AD Hingorani, , ,
Publication Date: 2009-11

Variant appearance in text: rs5072
PubMed Link: 19913121
Variant Present in the following documents:
  • mmc1.pdf
  • mmc2.xls
View BVdb publication page



Alternative transcript annotations:

Transcript cDNA Protein Consequence Exon Intron
ENST00000236850.4 c.200+134T>C - intron_variant - 3/3
ENST00000359492.2 c.200+134T>C - intron_variant - 3/3
ENST00000375320.1 c.200+134T>C - intron_variant - 3/3
ENST00000375323.1 c.200+134T>C - intron_variant - 2/2
ENST00000375329.2 c.135-456T>C - intron_variant - 1/1
ENST00000444200.1 n.123+628A>G - intron_variant,non_coding_transcript_variant - 1/1
NM_000039.2 c.200+134T>C - intron_variant - 3/3
NM_001318017.2 c.200+134T>C - intron_variant - 3/3
NM_001318018.2 c.200+134T>C - intron_variant - 3/3
NM_001318021.1 c.-128+134T>C - intron_variant - 3/3
NR_126362.1 n.123+628A>G - intron_variant,non_coding_transcript_variant - 1/1