KCNQ1 c.688_689delinsTG ;(p.I230C)

Variant ID: 11-2593247-AT-TG

NM_000218.2(KCNQ1):c.688_689delinsTG;(p.I230C)

This variant was identified in 5 publications

View GRCh38 version.




Publications:


Voltage-Dependent Gating: Novel Insights from KCNQ1 Channels.

Biophysical Journal
Cui, Jianmin J
Publication Date: 2016-01-05

Variant appearance in text: KCNQ1: I230C
PubMed Link: 26745405
Variant Present in the following documents:
  • Main text
View BVdb publication page



PIP2 regulation of KCNQ channels: biophysical and molecular mechanisms for lipid modulation of voltage-dependent gating.

Frontiers In Physiology
Zaydman, Mark A MA; Cui, Jianmin J
Publication Date: 2014

Variant appearance in text: KCNQ1: I230C
PubMed Link: 24904429
Variant Present in the following documents:
  • Main text
  • fphys-05-00195.pdf
View BVdb publication page



Kv7.1 ion channels require a lipid to couple voltage sensing to pore opening.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Zaydman, Mark A MA; Silva, Jonathan R JR; Delaloye, Kelli K; Li, Yang Y; Liang, Hongwu H; Larsson, H Peter HP; Shi, Jingyi J; Cui, Jianmin J
Publication Date: 2013-08-06

Variant appearance in text: Kv7.1: I230C
PubMed Link: 23861489
Variant Present in the following documents:
  • Main text
View BVdb publication page



KCNE peptides differently affect voltage sensor equilibrium and equilibration rates in KCNQ1 K+ channels.

The Journal Of General Physiology
Rocheleau, Jessica M JM; Kobertz, William R WR
Publication Date: 2008-01

Variant appearance in text: KCNQ1: I230C
PubMed Link: 18079560
Variant Present in the following documents:
  • Main text
  • jgp1310059.pdf
View BVdb publication page



KCNE1 and KCNE3 stabilize and/or slow voltage sensing S4 segment of KCNQ1 channel.

The Journal Of General Physiology
Nakajo, Koichi K; Kubo, Yoshihiro Y
Publication Date: 2007-09

Variant appearance in text: KCNQ1: I230C
PubMed Link: 17698596
Variant Present in the following documents:
  • Main text
View BVdb publication page