CRISPR-Cas9 globin editing can induce megabase-scale copy-neutral losses of heterozygosity in hematopoietic cells.
Nature Communications
Boutin, J J; Rosier, J J; Cappellen, D D; Prat, F F; Toutain, J J; Pennamen, P P; Bouron, J J; Rooryck, C C; Merlio, J P JP; Lamrissi-Garcia, I I; Cullot, G G; Amintas, S S; Guyonnet-Duperat, V V; Ged, C C; Blouin, J M JM; Richard, E E; Dabernat, S S; Moreau-Gaudry, F F; Bedel, A A
Differential methylation of the type 2 diabetes susceptibility locus KCNQ1 is associated with insulin sensitivity and is predicted by CpG site specific genetic variation.
Diabetes Research And Clinical Practice
Shah, Ushma J UJ; Xie, Weijia W; Flyvbjerg, Allan A; Nolan, John J JJ; Højlund, Kurt K; Walker, Mark M; Relton, Caroline L CL; Elliott, Hannah R HR; ,
Evaluation of allelic expression of imprinted genes in adult human blood.
Plos One
Frost, Jennifer M JM; Monk, Dave D; Stojilkovic-Mikic, Taita T; Woodfine, Kathryn K; Chitty, Lyn S LS; Murrell, Adele A; Stanier, Philip P; Moore, Gudrun E GE
The effects of culture on genomic imprinting profiles in human embryonic and fetal mesenchymal stem cells.
Epigenetics
Frost, Jennifer J; Monk, Dave D; Moschidou, Dafni D; Guillot, Pascale V PV; Stanier, Philip P; Minger, Stephen L SL; Fisk, Nicholas M NM; Moore, Harry D HD; Moore, Gudrun E GE