Characterization of Rheumatoid Arthritis Risk-Associated SNPs and Identification of Novel Therapeutic Sites Using an In-Silico Approach.
Biology
Akhtar, Mehran M; Ali, Yasir Y; Islam, Zia-Ul ZU; Arshad, Maria M; Rauf, Mamoona M; Ali, Muhammad M; Maodaa, Saleh N SN; Al-Farraj, Saleh A SA; El-Serehy, Hamed A HA; Jalil, Fazal F
Genetic variants of TRAF6 modulate peritoneal immunity and the risk of spontaneous bacterial peritonitis in cirrhosis: A combined prospective-retrospective study.
Scientific Reports
Mai, Martina M; Stengel, Sven S; Al-Herwi, Eihab E; Peter, Jack J; Schmidt, Caroline C; Rubio, Ignacio I; Stallmach, Andreas A; Bruns, Tony T
Identification of rheumatoid arthritis biomarkers based on single nucleotide polymorphisms and haplotype blocks: A systematic review and meta-analysis.
Journal Of Advanced Research
Saad, Mohamed N MN; Mabrouk, Mai S MS; Eldeib, Ayman M AM; Shaker, Olfat G OG
A genetic variant in osteoprotegerin is associated with progression of joint destruction in rheumatoid arthritis.
Arthritis Research & Therapy
Knevel, Rachel R; de Rooy, Diederik P C DP; Saxne, Tore T; Lindqvist, Elisabet E; Leijsma, Martha K MK; Daha, Nina A NA; Koeleman, Bobby P C BP; Tsonaka, Roula R; Houwing-Duistermaat, Jeanine J JJ; Schonkeren, Joris J M JJ; Toes, Rene E M RE; Huizinga, Tom W J TW; Brouwer, Elisabeth E; Wilson, Anthony G AG; van der Helm-van Mil, Annette H M AH
Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study.
Arthritis & Rheumatology (Hoboken, N.J.)
Orozco, Gisela G; Viatte, Sebastien S; Bowes, John J; Martin, Paul P; Wilson, Anthony G AG; Morgan, Ann W AW; Steer, Sophia S; Wordsworth, Paul P; Hocking, Lynne J LJ; , ; , ; , ; Barton, Anne A; Worthington, Jane J; Eyre, Stephen S
Predicting the risk of rheumatoid arthritis and its age of onset through modelling genetic risk variants with smoking.
Plos Genetics
Scott, Ian C IC; Seegobin, Seth D SD; Steer, Sophia S; Tan, Rachael R; Forabosco, Paola P; Hinks, Anne A; Eyre, Stephen S; Morgan, Ann W AW; Wilson, Anthony G AG; Hocking, Lynne J LJ; Wordsworth, Paul P; Barton, Anne A; Worthington, Jane J; Cope, Andrew P AP; Lewis, Cathryn M CM
Identification of the tyrosine-protein phosphatase non-receptor type 2 as a rheumatoid arthritis susceptibility locus in europeans.
Plos One
Cobb, Joanna E JE; Plant, Darren D; Flynn, Edward E; Tadjeddine, Meriem M; Dieudé, Philippe P; Cornélis, François F; Ärlestig, Lisbeth L; Dahlqvist, Solbritt Rantapää SR; Goulielmos, George G; Boumpas, Dimitrios T DT; Sidiropoulos, Prodromos P; Krintel, Sophine B SB; Ørnbjerg, Lykke M LM; Hetland, Merete L ML; Klareskog, Lars L; Haeupl, Thomas T; Filer, Andrew A; Buckley, Christopher D CD; Raza, Karim K; Witte, Torsten T; Schmidt, Reinhold E RE; FitzGerald, Oliver O; Veale, Douglas D; Eyre, Stephen S; Worthington, Jane J
Genetics of SLE: functional relevance for monocytes/macrophages in disease.
Clinical & Developmental Immunology
Byrne, Jennifer C JC; Ní Gabhann, Joan J; Lazzari, Elisa E; Mahony, Rebecca R; Smith, Siobhán S; Stacey, Kevin K; Wynne, Claire C; Jefferies, Caroline A CA
Use of a multiethnic approach to identify rheumatoid- arthritis-susceptibility loci, 1p36 and 17q12.
American Journal Of Human Genetics
Kurreeman, Fina A S FA; Stahl, Eli A EA; Okada, Yukinori Y; Liao, Katherine K; Diogo, Dorothée D; Raychaudhuri, Soumya S; Freudenberg, Jan J; Kochi, Yuta Y; Patsopoulos, Nikolaos A NA; Gupta, Namrata N; , ; Sandor, Cynthia C; Bang, So-Young SY; Lee, Hye-Soon HS; Padyukov, Leonid L; Suzuki, Akari A; Siminovitch, Kathy K; Worthington, Jane J; Gregersen, Peter K PK; Hughes, Laura B LB; Reynolds, Richard J RJ; Bridges, S Louis SL; Bae, Sang-Cheol SC; Yamamoto, Kazuhiko K; Plenge, Robert M RM
Comprehensive assessment of rheumatoid arthritis susceptibility loci in a large psoriatic arthritis cohort.
Annals Of The Rheumatic Diseases
Bowes, John J; Ho, Pauline P; Flynn, Edward E; Ali, Faisal F; Marzo-Ortega, Helena H; Coates, Laura C LC; Warren, Richard B RB; McManus, Ross R; Ryan, Anthony W AW; Kane, David D; Korendowych, Eleanor E; McHugh, Neil N; FitzGerald, Oliver O; Packham, Jonathon J; Morgan, Ann W AW; Bruce, Ian N IN; Barton, Anne A
Evaluation of TRAF6 in a large multiancestral lupus cohort.
Arthritis And Rheumatism
Namjou, Bahram B; Choi, Chan-Bum CB; Harley, Isaac T W IT; Alarcón-Riquelme, Marta E ME; , ; Kelly, Jennifer A JA; Glenn, Stuart B SB; Ojwang, Joshua O JO; Adler, Adam A; Kim, Kwangwoo K; Gallant, Caroline J CJ; Boackle, Susan A SA; Criswell, Lindsey A LA; Kimberly, Robert P RP; Brown, Elizabeth E EE; Edberg, Jeffrey J; Alarcón, Graciela S GS; Stevens, Anne M AM; Jacob, Chaim O CO; Gilkeson, Gary S GS; Kamen, Diane L DL; Tsao, Betty P BP; Anaya, Juan-Manuel JM; Kim, Eun-Mi EM; Park, So-Yeon SY; Sung, Yoon-Kyoung YK; Guthridge, Joel M JM; Merrill, Joan T JT; Petri, Michelle M; Ramsey-Goldman, Rosalind R; Vilá, Luis M LM; Niewold, Timothy B TB; Martin, Javier J; Pons-Estel, Bernardo A BA; , ; Vyse, Timothy J TJ; Freedman, Barry I BI; Moser, Kathy L KL; Gaffney, Patrick M PM; Williams, Adrienne H AH; Comeau, Mary E ME; Reveille, John D JD; Kang, Changwon C; James, Judith A JA; Scofield, R Hal RH; Langefeld, Carl D CD; Kaufman, Kenneth M KM; Harley, John B JB; Bae, Sang-Cheol SC
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.
Nature Genetics
Stahl, Eli A EA; Raychaudhuri, Soumya S; Remmers, Elaine F EF; Xie, Gang G; Eyre, Stephen S; Thomson, Brian P BP; Li, Yonghong Y; Kurreeman, Fina A S FA; Zhernakova, Alexandra A; Hinks, Anne A; Guiducci, Candace C; Chen, Robert R; Alfredsson, Lars L; Amos, Christopher I CI; Ardlie, Kristin G KG; , ; Barton, Anne A; Bowes, John J; Brouwer, Elisabeth E; Burtt, Noel P NP; Catanese, Joseph J JJ; Coblyn, Jonathan J; Coenen, Marieke J H MJ; Costenbader, Karen H KH; Criswell, Lindsey A LA; Crusius, J Bart A JB; Cui, Jing J; de Bakker, Paul I W PI; De Jager, Philip L PL; Ding, Bo B; Emery, Paul P; Flynn, Edward E; Harrison, Pille P; Hocking, Lynne J LJ; Huizinga, Tom W J TW; Kastner, Daniel L DL; Ke, Xiayi X; Lee, Annette T AT; Liu, Xiangdong X; Martin, Paul P; Morgan, Ann W AW; Padyukov, Leonid L; Posthumus, Marcel D MD; Radstake, Timothy R D J TR; Reid, David M DM; Seielstad, Mark M; Seldin, Michael F MF; Shadick, Nancy A NA; Steer, Sophia S; Tak, Paul P PP; Thomson, Wendy W; van der Helm-van Mil, Annette H M AH; van der Horst-Bruinsma, Irene E IE; van der Schoot, C Ellen CE; van Riel, Piet L C M PL; Weinblatt, Michael E ME; Wilson, Anthony G AG; Wolbink, Gert Jan GJ; Wordsworth, B Paul BP; , ; Wijmenga, Cisca C; Karlson, Elizabeth W EW; Toes, Rene E M RE; de Vries, Niek N; Begovich, Ann B AB; Worthington, Jane J; Siminovitch, Katherine A KA; Gregersen, Peter K PK; Klareskog, Lars L; Plenge, Robert M RM
Rheumatoid arthritis risk allele PTPRC is also associated with response to anti-tumor necrosis factor alpha therapy.
Arthritis And Rheumatism
Cui, Jing J; Saevarsdottir, Saedis S; Thomson, Brian B; Padyukov, Leonid L; van der Helm-van Mil, Annette H M AH; Nititham, Joanne J; Hughes, Laura B LB; de Vries, Niek N; Raychaudhuri, Soumya S; Alfredsson, Lars L; Askling, Johan J; Wedrén, Sara S; Ding, Bo B; Guiducci, Candace C; Wolbink, Gert Jan GJ; Crusius, J Bart A JB; van der Horst-Bruinsma, Irene E IE; Herenius, Marieke M; Weinblatt, Michael E ME; Shadick, Nancy A NA; Worthington, Jane J; Batliwalla, Franak F; Kern, Marlena M; Morgan, Ann W AW; Wilson, Anthony G AG; Isaacs, John D JD; Hyrich, Kimme K; Seldin, Michael F MF; Moreland, Larry W LW; Behrens, Timothy W TW; Allaart, Cornelia F CF; Criswell, Lindsey A LA; Huizinga, Tom W J TW; Tak, Paul P PP; Bridges, S Louis SL; Toes, Rene E M RE; Barton, Anne A; Klareskog, Lars L; Gregersen, Peter K PK; Karlson, Elizabeth W EW; Plenge, Robert M RM
Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk.
Nature Genetics
Raychaudhuri, Soumya S; Thomson, Brian P BP; Remmers, Elaine F EF; Eyre, Stephen S; Hinks, Anne A; Guiducci, Candace C; Catanese, Joseph J JJ; Xie, Gang G; Stahl, Eli A EA; Chen, Robert R; Alfredsson, Lars L; Amos, Christopher I CI; Ardlie, Kristin G KG; , ; Barton, Anne A; Bowes, John J; Burtt, Noel P NP; Chang, Monica M; Coblyn, Jonathan J; Costenbader, Karen H KH; Criswell, Lindsey A LA; Crusius, J Bart A JB; Cui, Jing J; De Jager, Phillip L PL; Ding, Bo B; Emery, Paul P; Flynn, Edward E; Harrison, Pille P; Hocking, Lynne J LJ; Huizinga, Tom W J TW; Kastner, Daniel L DL; Ke, Xiayi X; Kurreeman, Fina A S FA; Lee, Annette T AT; Liu, Xiangdong X; Li, Yonghong Y; Martin, Paul P; Morgan, Ann W AW; Padyukov, Leonid L; Reid, David M DM; Seielstad, Mark M; Seldin, Michael F MF; Shadick, Nancy A NA; Steer, Sophia S; Tak, Paul P PP; Thomson, Wendy W; van der Helm-van Mil, Annette H M AH; van der Horst-Bruinsma, Irene E IE; Weinblatt, Michael E ME; Wilson, Anthony G AG; Wolbink, Gert Jan GJ; Wordsworth, Paul P; , ; Altshuler, David D; Karlson, Elizabeth W EW; Toes, Rene E M RE; de Vries, Niek N; Begovich, Ann B AB; Siminovitch, Katherine A KA; Worthington, Jane J; Klareskog, Lars L; Gregersen, Peter K PK; Daly, Mark J MJ; Plenge, Robert M RM