Rap1 binding and a lipid-dependent helix in talin F1 domain promote integrin activation in tandem.
The Journal Of Cell Biology
Gingras, Alexandre R AR; Lagarrigue, Frederic F; Cuevas, Monica N MN; Valadez, Andrew J AJ; Zorovich, Marcus M; McLaughlin, Wilma W; Lopez-Ramirez, Miguel Alejandro MA; Seban, Nicolas N; Ley, Klaus K; Kiosses, William B WB; Ginsberg, Mark H MH
Structure of Rap1b bound to talin reveals a pathway for triggering integrin activation.
Nature Communications
Zhu, Liang L; Yang, Jun J; Bromberger, Thomas T; Holly, Ashley A; Lu, Fan F; Liu, Huan H; Sun, Kevin K; Klapproth, Sarah S; Hirbawi, Jamila J; Byzova, Tatiana V TV; Plow, Edward F EF; Moser, Markus M; Qin, Jun J