F2 c.103_104delinsGC ;(p.R35A)

Variant ID: 11-46741275-CG-GC

NM_000506.3(F2):c.103_104delinsGC;(p.R35A)

This variant was identified in 5 publications

View GRCh38 version.




Publications:


Structural Basis of β2 Integrin Inside-Out Activation.

Cells
Wen, Lai L; Lyu, Qingkang Q; Ley, Klaus K; Goult, Benjamin T BT
Publication Date: 2022-09-28

Variant appearance in text: F2: R35A
PubMed Link: 36231001
Variant Present in the following documents:
  • Main text
  • cells-11-03039.pdf
View BVdb publication page



The Connection Between Rap1 and Talin1 in the Activation of Integrins in Blood Cells.

Frontiers In Cell And Developmental Biology
Sun, Hao H; Lagarrigue, Frederic F; Ginsberg, Mark H MH
Publication Date: 2022

Variant appearance in text: F2: R35A
PubMed Link: 35721481
Variant Present in the following documents:
  • fcell-10-908622.pdf
View BVdb publication page



Rap1 and membrane lipids cooperatively recruit talin to trigger integrin activation.

Journal Of Cell Science
Bromberger, Thomas T; Zhu, Liang L; Klapproth, Sarah S; Qin, Jun J; Moser, Markus M
Publication Date: 2019-11-01

Variant appearance in text: F2: R35A
PubMed Link: 31578239
Variant Present in the following documents:
  • Main text
View BVdb publication page



Rap1 binding and a lipid-dependent helix in talin F1 domain promote integrin activation in tandem.

The Journal Of Cell Biology
Gingras, Alexandre R AR; Lagarrigue, Frederic F; Cuevas, Monica N MN; Valadez, Andrew J AJ; Zorovich, Marcus M; McLaughlin, Wilma W; Lopez-Ramirez, Miguel Alejandro MA; Seban, Nicolas N; Ley, Klaus K; Kiosses, William B WB; Ginsberg, Mark H MH
Publication Date: 2019-06-03

Variant appearance in text: F2: R35A
PubMed Link: 30988001
Variant Present in the following documents:
  • Main text
  • JCB_201810061.pdf
View BVdb publication page



Structure of Rap1b bound to talin reveals a pathway for triggering integrin activation.

Nature Communications
Zhu, Liang L; Yang, Jun J; Bromberger, Thomas T; Holly, Ashley A; Lu, Fan F; Liu, Huan H; Sun, Kevin K; Klapproth, Sarah S; Hirbawi, Jamila J; Byzova, Tatiana V TV; Plow, Edward F EF; Moser, Markus M; Qin, Jun J
Publication Date: 2017-11-23

Variant appearance in text: F2: R35A
PubMed Link: 29170462
Variant Present in the following documents:
  • Main text
  • 41467_2017_Article_1822.pdf
View BVdb publication page