JAK-STAT signaling in inflammatory breast cancer enables chemotherapy-resistant cell states.
Cancer Research
Stevens, Laura E LE; Peluffo, Guillermo G; Qiu, Xintao X; Temko, Daniel D; Fassl, Anne A; Li, Zheqi Z; Trinh, Anne A; Seehawer, Marco M; Jovanovic, Bojana B; Aleckovic, Masa M; Wilde, Callahan M CM; Geck, Renee C RC; Shu, Shaokun S; Kingston, Natalie L NL; Harper, Nicholas W NW; Almendro, Vanessa V; Pyke, Alanna L AL; Egri, Shawn B SB; Papanastasiou, Malvina M; Clement, Kendell K; Zhou, Ningxuan N; Walker, Sarah S; Salas, Jacqueline J; Park, So Yeon SY; Frank, David A DA; Meissner, Alexander A; Jaffe, Jacob D JD; Sicinski, Piotr P; Toker, Alex A; Michor, Franziska F; Long, Henry W HW; Overmoyer, Beth A BA; Polyak, Kornelia K
Publication Date: 2022-11-21
Variant appearance in text: F2: 423-7G>C; rs2070852
Next-generation whole exome sequencing to delineate the genetic basis of primary congenital glaucoma.
Scientific Reports
Rauf, Bushra B; Khan, Shahid Y SY; Jiao, Xiaodong X; Irum, Bushra B; Ashfaq, Ramla R; Zehra, Mubashra M; Khan, Asma A AA; Naeem, Muhammad Asif MA; Shahzad, Mohsin M; Riazuddin, Sheikh S; Hejtmancik, J Fielding JF; Riazuddin, S Amer SA
Genetic analysis of sinonasal undifferentiated carcinoma discovers recurrent SWI/SNF alterations and a novel PGAP3-SRPK1 fusion gene.
Bmc Cancer
Heft Neal, Molly E ME; Birkeland, Andrew C AC; Bhangale, Apurva D AD; Zhai, Jingyi J; Kulkarni, Aditi A; Foltin, Susan K SK; Jewell, Brittany M BM; Ludwig, Megan L ML; Pinatti, Lisa L; Jiang, Hui H; McHugh, Jonathan B JB; Marentette, Lawence L; McKean, Erin L EL; Brenner, J Chad JC
Publication Date: 2021-05-29
Variant appearance in text: F2: 423-7G>C; rs2070852
A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis.
Communications Biology
Bell, Steven S; Rigas, Andreas S AS; Magnusson, Magnus K MK; Ferkingstad, Egil E; Allara, Elias E; Bjornsdottir, Gyda G; Ramond, Anna A; Sørensen, Erik E; Halldorsson, Gisli H GH; Paul, Dirk S DS; Burgdorf, Kristoffer S KS; Eggertsson, Hannes P HP; Howson, Joanna M M JMM; Thørner, Lise W LW; Kristmundsdottir, Snaedis S; Astle, William J WJ; Erikstrup, Christian C; Sigurdsson, Jon K JK; Vuckovic, Dragana D; Dinh, Khoa M KM; Tragante, Vinicius V; Surendran, Praveen P; Pedersen, Ole B OB; Vidarsson, Brynjar B; Jiang, Tao T; Paarup, Helene M HM; Onundarson, Pall T PT; Akbari, Parsa P; Nielsen, Kaspar R KR; Lund, Sigrun H SH; Juliusson, Kristinn K; Magnusson, Magnus I MI; Frigge, Michael L ML; Oddsson, Asmundur A; Olafsson, Isleifur I; Kaptoge, Stephen S; Hjalgrim, Henrik H; Runarsson, Gudmundur G; Wood, Angela M AM; Jonsdottir, Ingileif I; Hansen, Thomas F TF; Sigurdardottir, Olof O; Stefansson, Hreinn H; Rye, David D; , ; Peters, James E JE; Westergaard, David D; Holm, Hilma H; Soranzo, Nicole N; Banasik, Karina K; Thorleifsson, Gudmar G; Ouwehand, Willem H WH; Thorsteinsdottir, Unnur U; Roberts, David J DJ; Sulem, Patrick P; Butterworth, Adam S AS; Gudbjartsson, Daniel F DF; Danesh, John J; Brunak, Søren S; Di Angelantonio, Emanuele E; Ullum, Henrik H; Stefansson, Kari K
Publication Date: 2021-02-03
Variant appearance in text: F2: 423-7G>C; rs2070852
Genome-wide association of phenotypes based on clustering patterns of hand osteoarthritis identify WNT9A as novel osteoarthritis gene.
Annals Of The Rheumatic Diseases
Boer, Cindy Germaine CG; Yau, Michelle S MS; Rice, Sarah J SJ; Coutinho de Almeida, Rodrigo R; Cheung, Kathleen K; Styrkarsdottir, Unnur U; Southam, Lorraine L; Broer, Linda L; Wilkinson, Jeremy Mark JM; Uitterlinden, André G AG; Zeggini, Eleftheria E; Felson, David D; Loughlin, John J; Young, Mariel M; Capellini, Terence Dante TD; Meulenbelt, Ingrid I; van Meurs, Joyce Bj JB
Genome-wide association of phenotypes based on clustering patterns of hand osteoarthritis identify WNT9A as novel osteoarthritis gene.
Annals Of The Rheumatic Diseases
Boer, Cindy Germaine CG; Yau, Michelle S MS; Rice, Sarah J SJ; Coutinho de Almeida, Rodrigo R; Cheung, Kathleen K; Styrkarsdottir, Unnur U; Southam, Lorraine L; Broer, Linda L; Wilkinson, Jeremy Mark JM; Uitterlinden, André G AG; Zeggini, Eleftheria E; Felson, David D; Loughlin, John J; Young, Mariel M; Capellini, Terence Dante TD; Meulenbelt, Ingrid I; van Meurs, Joyce Bj JB
Distinctive mutational spectrum and karyotype disruption in long-term cisplatin-treated urothelial carcinoma cell lines.
Scientific Reports
Skowron, Margaretha A MA; Petzsch, Patrick P; Hardt, Karin K; Wagner, Nicholas N; Beier, Manfred M; Stepanow, Stefanie S; Drechsler, Matthias M; Rieder, Harald H; Köhrer, Karl K; Niegisch, Günter G; Hoffmann, Michèle J MJ; Schulz, Wolfgang A WA
Organoids as a new model for improving regenerative medicine and cancer personalized therapy in renal diseases.
Cell Death & Disease
Grassi, Ludovica L; Alfonsi, Romina R; Francescangeli, Federica F; Signore, Michele M; De Angelis, Maria Laura ML; Addario, Antonio A; Costantini, Manuela M; Flex, Elisabetta E; Ciolfi, Andrea A; Pizzi, Simone S; Bruselles, Alessandro A; Pallocca, Matteo M; Simone, Giuseppe G; Haoui, Mustapha M; Falchi, Mario M; Milella, Michele M; Sentinelli, Steno S; Di Matteo, Paola P; Stellacci, Emilia E; Gallucci, Michele M; Muto, Giovanni G; Tartaglia, Marco M; De Maria, Ruggero R; Bonci, Désirée D
Publication Date: 2019-02-27
Variant appearance in text: F2: 423-7G>C; rs2070852
Generation of a High Number of Healthy Erythroid Cells from Gene-Edited Pyruvate Kinase Deficiency Patient-Specific Induced Pluripotent Stem Cells.
Stem Cell Reports
Garate, Zita Z; Quintana-Bustamante, Oscar O; Crane, Ana M AM; Olivier, Emmanuel E; Poirot, Laurent L; Galetto, Roman R; Kosinski, Penelope P; Hill, Collin C; Kung, Charles C; Agirre, Xabi X; Orman, Israel I; Cerrato, Laura L; Alberquilla, Omaira O; Rodriguez-Fornes, Fatima F; Fusaki, Noemi N; Garcia-Sanchez, Felix F; Maia, Tabita M TM; Ribeiro, Maria L ML; Sevilla, Julian J; Prosper, Felipe F; Jin, Shengfang S; Mountford, Joanne J; Guenechea, Guillermo G; Gouble, Agnes A; Bueren, Juan A JA; Davis, Brian R BR; Segovia, Jose C JC
Tumor expression, plasma levels and genetic polymorphisms of the coagulation inhibitor TFPI are associated with clinicopathological parameters and survival in breast cancer, in contrast to the coagulation initiator TF.
Breast Cancer Research : Bcr
Tinholt, Mari M; Vollan, Hans Kristian Moen HK; Sahlberg, Kristine Kleivi KK; Jernström, Sandra S; Kaveh, Fatemeh F; Lingjærde, Ole Christian OC; Kåresen, Rolf R; Sauer, Torill T; Kristensen, Vessela V; Børresen-Dale, Anne-Lise AL; Sandset, Per Morten PM; Iversen, Nina N
Increased coagulation activity and genetic polymorphisms in the F5, F10 and EPCR genes are associated with breast cancer: a case-control study.
Bmc Cancer
Tinholt, Mari M; Viken, Marte Kathrine MK; Dahm, Anders Erik AE; Vollan, Hans Kristian Moen HK; Sahlberg, Kristine Kleivi KK; Garred, Oystein O; Børresen-Dale, Anne-Lise AL; Jacobsen, Anne Flem AF; Kristensen, Vessela V; Bukholm, Ida I; Kåresen, Rolf R; Schlichting, Ellen E; Skretting, Grethe G; Lie, Benedicte Alexandra BA; Sandset, Per Morten PM; Iversen, Nina N
Impact of common variation in bone-related genes on type 2 diabetes and related traits.
Diabetes
Billings, Liana K LK; Hsu, Yi-Hsiang YH; Ackerman, Rachel J RJ; Dupuis, Josée J; Voight, Benjamin F BF; Rasmussen-Torvik, Laura J LJ; Hercberg, Serge S; Lathrop, Mark M; Barnes, Daniel D; Langenberg, Claudia C; Hui, Jennie J; Fu, Mao M; Bouatia-Naji, Nabila N; Lecoeur, Cecile C; An, Ping P; Magnusson, Patrik K PK; Surakka, Ida I; Ripatti, Samuli S; Christiansen, Lene L; Dalgård, Christine C; Folkersen, Lasse L; Grundberg, Elin E; , ; , ; , ; , ; , ; Eriksson, Per P; Kaprio, Jaakko J; Ohm Kyvik, Kirsten K; Pedersen, Nancy L NL; Borecki, Ingrid B IB; Province, Michael A MA; Balkau, Beverley B; Froguel, Philippe P; Shuldiner, Alan R AR; Palmer, Lyle J LJ; Wareham, Nick N; Meneton, Pierre P; Johnson, Toby T; Pankow, James S JS; Karasik, David D; Meigs, James B JB; Kiel, Douglas P DP; Florez, Jose C JC
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.
Nature Genetics
Estrada, Karol K; Styrkarsdottir, Unnur U; Evangelou, Evangelos E; Hsu, Yi-Hsiang YH; Duncan, Emma L EL; Ntzani, Evangelia E EE; Oei, Ling L; Albagha, Omar M E OM; Amin, Najaf N; Kemp, John P JP; Koller, Daniel L DL; Li, Guo G; Liu, Ching-Ti CT; Minster, Ryan L RL; Moayyeri, Alireza A; Vandenput, Liesbeth L; Willner, Dana D; Xiao, Su-Mei SM; Yerges-Armstrong, Laura M LM; Zheng, Hou-Feng HF; Alonso, Nerea N; Eriksson, Joel J; Kammerer, Candace M CM; Kaptoge, Stephen K SK; Leo, Paul J PJ; Thorleifsson, Gudmar G; Wilson, Scott G SG; Wilson, James F JF; Aalto, Ville V; Alen, Markku M; Aragaki, Aaron K AK; Aspelund, Thor T; Center, Jacqueline R JR; Dailiana, Zoe Z; Duggan, David J DJ; Garcia, Melissa M; Garcia-Giralt, Natàlia N; Giroux, Sylvie S; Hallmans, Göran G; Hocking, Lynne J LJ; Husted, Lise Bjerre LB; Jameson, Karen A KA; Khusainova, Rita R; Kim, Ghi Su GS; Kooperberg, Charles C; Koromila, Theodora T; Kruk, Marcin M; Laaksonen, Marika M; Lacroix, Andrea Z AZ; Lee, Seung Hun SH; Leung, Ping C PC; Lewis, Joshua R JR; Masi, Laura L; Mencej-Bedrac, Simona S; Nguyen, Tuan V TV; Nogues, Xavier X; Patel, Millan S MS; Prezelj, Janez J; Rose, Lynda M LM; Scollen, Serena S; Siggeirsdottir, Kristin K; Smith, Albert V AV; Svensson, Olle O; Trompet, Stella S; Trummer, Olivia O; van Schoor, Natasja M NM; Woo, Jean J; Zhu, Kun K; Balcells, Susana S; Brandi, Maria Luisa ML; Buckley, Brendan M BM; Cheng, Sulin S; Christiansen, Claus C; Cooper, Cyrus C; Dedoussis, George G; Ford, Ian I; Frost, Morten M; Goltzman, David D; González-Macías, Jesús J; Kähönen, Mika M; Karlsson, Magnus M; Khusnutdinova, Elza E; Koh, Jung-Min JM; Kollia, Panagoula P; Langdahl, Bente Lomholt BL; Leslie, William D WD; Lips, Paul P; Ljunggren, Östen Ö; Lorenc, Roman S RS; Marc, Janja J; Mellström, Dan D; Obermayer-Pietsch, Barbara B; Olmos, José M JM; Pettersson-Kymmer, Ulrika U; Reid, David M DM; Riancho, José A JA; Ridker, Paul M PM; Rousseau, François F; Slagboom, P Eline PE; Tang, Nelson L S NL; Urreizti, Roser R; Van Hul, Wim W; Viikari, Jorma J; Zarrabeitia, María T MT; Aulchenko, Yurii S YS; Castano-Betancourt, Martha M; Grundberg, Elin E; Herrera, Lizbeth L; Ingvarsson, Thorvaldur T; Johannsdottir, Hrefna H; Kwan, Tony T; Li, Rui R; Luben, Robert R; Medina-Gómez, Carolina C; Palsson, Stefan Th ST; Reppe, Sjur S; Rotter, Jerome I JI; Sigurdsson, Gunnar G; van Meurs, Joyce B J JB; Verlaan, Dominique D; Williams, Frances M K FM; Wood, Andrew R AR; Zhou, Yanhua Y; Gautvik, Kaare M KM; Pastinen, Tomi T; Raychaudhuri, Soumya S; Cauley, Jane A JA; Chasman, Daniel I DI; Clark, Graeme R GR; Cummings, Steven R SR; Danoy, Patrick P; Dennison, Elaine M EM; Eastell, Richard R; Eisman, John A JA; Gudnason, Vilmundur V; Hofman, Albert A; Jackson, Rebecca D RD; Jones, Graeme G; Jukema, J Wouter JW; Khaw, Kay-Tee KT; Lehtimäki, Terho T; Liu, Yongmei Y; Lorentzon, Mattias M; McCloskey, Eugene E; Mitchell, Braxton D BD; Nandakumar, Kannabiran K; Nicholson, Geoffrey C GC; Oostra, Ben A BA; Peacock, Munro M; Pols, Huibert A P HA; Prince, Richard L RL; Raitakari, Olli O; Reid, Ian R IR; Robbins, John J; Sambrook, Philip N PN; Sham, Pak Chung PC; Shuldiner, Alan R AR; Tylavsky, Frances A FA; van Duijn, Cornelia M CM; Wareham, Nick J NJ; Cupples, L Adrienne LA; Econs, Michael J MJ; Evans, David M DM; Harris, Tamara B TB; Kung, Annie Wai Chee AW; Psaty, Bruce M BM; Reeve, Jonathan J; Spector, Timothy D TD; Streeten, Elizabeth A EA; Zillikens, M Carola MC; Thorsteinsdottir, Unnur U; Ohlsson, Claes C; Karasik, David D; Richards, J Brent JB; Brown, Matthew A MA; Stefansson, Kari K; Uitterlinden, André G AG; Ralston, Stuart H SH; Ioannidis, John P A JP; Kiel, Douglas P DP; Rivadeneira, Fernando F
SNPs associated with cerebrospinal fluid phospho-tau levels influence rate of decline in Alzheimer's disease.
Plos Genetics
Cruchaga, Carlos C; Kauwe, John S K JS; Mayo, Kevin K; Spiegel, Noah N; Bertelsen, Sarah S; Nowotny, Petra P; Shah, Aarti R AR; Abraham, Richard R; Hollingworth, Paul P; Harold, Denise D; Owen, Michael M MM; Williams, Julie J; Lovestone, Simon S; Peskind, Elaine R ER; Li, Ge G; Leverenz, James B JB; Galasko, Douglas D; , ; Morris, John C JC; Fagan, Anne M AM; Holtzman, David M DM; Goate, Alison M AM
Collaborative meta-analysis: associations of 150 candidate genes with osteoporosis and osteoporotic fracture.
Annals Of Internal Medicine
Richards, J Brent JB; Kavvoura, Fotini K FK; Rivadeneira, Fernando F; Styrkársdóttir, Unnur U; Estrada, Karol K; Halldórsson, Bjarni V BV; Hsu, Yi-Hsiang YH; Zillikens, M Carola MC; Wilson, Scott G SG; Mullin, Benjamin H BH; Amin, Najaf N; Aulchenko, Yurii S YS; Cupples, L Adrienne LA; Deloukas, Panagiotis P; Demissie, Serkalem S; Hofman, Albert A; Kong, Augustine A; Karasik, David D; van Meurs, Joyce B JB; Oostra, Ben A BA; Pols, Huibert A P HA; Sigurdsson, Gunnar G; Thorsteinsdottir, Unnur U; Soranzo, Nicole N; Williams, Frances M K FM; Zhou, Yanhua Y; Ralston, Stuart H SH; Thorleifsson, Gudmar G; van Duijn, Cornelia M CM; Kiel, Douglas P DP; Stefansson, Kari K; Uitterlinden, André G AG; Ioannidis, John P A JP; Spector, Tim D TD; ,
Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.
Nature Genetics
Rivadeneira, Fernando F; Styrkársdottir, Unnur U; Estrada, Karol K; Halldórsson, Bjarni V BV; Hsu, Yi-Hsiang YH; Richards, J Brent JB; Zillikens, M Carola MC; Kavvoura, Fotini K FK; Amin, Najaf N; Aulchenko, Yurii S YS; Cupples, L Adrienne LA; Deloukas, Panagiotis P; Demissie, Serkalem S; Grundberg, Elin E; Hofman, Albert A; Kong, Augustine A; Karasik, David D; van Meurs, Joyce B JB; Oostra, Ben B; Pastinen, Tomi T; Pols, Huibert A P HA; Sigurdsson, Gunnar G; Soranzo, Nicole N; Thorleifsson, Gudmar G; Thorsteinsdottir, Unnur U; Williams, Frances M K FM; Wilson, Scott G SG; Zhou, Yanhua Y; Ralston, Stuart H SH; van Duijn, Cornelia M CM; Spector, Timothy T; Kiel, Douglas P DP; Stefansson, Kari K; Ioannidis, John P A JP; Uitterlinden, André G AG; ,
Ikram, M Arfan MA; Seshadri, Sudha S; Bis, Joshua C JC; Fornage, Myriam M; DeStefano, Anita L AL; Aulchenko, Yurii S YS; Debette, Stephanie S; Lumley, Thomas T; Folsom, Aaron R AR; van den Herik, Evita G EG; Bos, Michiel J MJ; Beiser, Alexa A; Cushman, Mary M; Launer, Lenore J LJ; Shahar, Eyal E; Struchalin, Maksim M; Du, Yangchun Y; Glazer, Nicole L NL; Rosamond, Wayne D WD; Rivadeneira, Fernando F; Kelly-Hayes, Margaret M; Lopez, Oscar L OL; Coresh, Josef J; Hofman, Albert A; DeCarli, Charles C; Heckbert, Susan R SR; Koudstaal, Peter J PJ; Yang, Qiong Q; Smith, Nicholas L NL; Kase, Carlos S CS; Rice, Kenneth K; Haritunians, Talin T; Roks, Gerwin G; de Kort, Paul L M PL; Taylor, Kent D KD; de Lau, Lonneke M LM; Oostra, Ben A BA; Uitterlinden, Andre G AG; Rotter, Jerome I JI; Boerwinkle, Eric E; Psaty, Bruce M BM; Mosley, Thomas H TH; van Duijn, Cornelia M CM; Breteler, Monique M B MM; Longstreth, W T WT; Wolf, Philip A PA
Association of warfarin dose with genes involved in its action and metabolism.
Human Genetics
Wadelius, Mia M; Chen, Leslie Y LY; Eriksson, Niclas N; Bumpstead, Suzannah S; Ghori, Jilur J; Wadelius, Claes C; Bentley, David D; McGinnis, Ralph R; Deloukas, Panos P