Association between genetic risk score and tri-ponderal mass index growth trajectories among different dietary consumption adolescents in a prospective Taiwanese cohort.
Polygenic risk scores predict diabetes complications and their response to intensive blood pressure and glucose control.
Diabetologia
Tremblay, Johanne J; Haloui, Mounsif M; Attaoua, Redha R; Tahir, Ramzan R; Hishmih, Camil C; Harvey, François F; Marois-Blanchet, François-Christophe FC; Long, Carole C; Simon, Paul P; Santucci, Lara L; Hizel, Candan C; Chalmers, John J; Marre, Michel M; Harrap, Stephen S; Cífková, Renata R; Krajčoviechová, Alena A; Matthews, David R DR; Williams, Bryan B; Poulter, Neil N; Zoungas, Sophia S; Colagiuri, Stephen S; Mancia, Giuseppe G; Grobbee, Diederick E DE; Rodgers, Anthony A; Liu, Liusheng L; Agbessi, Mawussé M; Bruat, Vanessa V; Favé, Marie-Julie MJ; Harwood, Michelle P MP; Awadalla, Philip P; Woodward, Mark M; Hussin, Julie G JG; Hamet, Pavel P
The Role of Inflammatory Cytokines as Intermediates in the Pathway from Increased Adiposity to Disease.
Obesity (Silver Spring, Md.)
Kalaoja, Marita M; Corbin, Laura J LJ; Tan, Vanessa Y VY; Ahola-Olli, Ari V AV; Havulinna, Aki S AS; Santalahti, Kristiina K; Pitkänen, Niina N; Lehtimäki, Terho T; Lyytikäinen, Leo-Pekka LP; Raitoharju, Emma E; Seppälä, Ilkka I; Kähönen, Mika M; Ripatti, Samuli S; Palotie, Aarno A; Perola, Markus M; Viikari, Jorma S JS; Jalkanen, Sirpa S; Maksimow, Mikael M; Salomaa, Veikko V; Salmi, Marko M; Raitakari, Olli T OT; Kettunen, Johannes J; Timpson, Nicholas J NJ
An Integrative Phenotype-Genotype Approach Using Phenotypic Characteristics from the UAE National Diabetes Study Identifies HSD17B12 as a Candidate Gene for Obesity and Type 2 Diabetes.
Genes
Hachim, Mahmood Y MY; Aljaibeji, Hayat H; Hamoudi, Rifat A RA; Hachim, Ibrahim Y IY; Elemam, Noha M NM; Mohammed, Abdul Khader AK; Salehi, Albert A; Taneera, Jalal J; Sulaiman, Nabil N
Body mass index and all cause mortality in HUNT and UK Biobank studies: linear and non-linear mendelian randomisation analyses.
Bmj (Clinical Research Ed.)
Sun, Yi-Qian YQ; Burgess, Stephen S; Staley, James R JR; Wood, Angela M AM; Bell, Steven S; Kaptoge, Stephen K SK; Guo, Qi Q; Bolton, Thomas R TR; Mason, Amy M AM; Butterworth, Adam S AS; Di Angelantonio, Emanuele E; Vie, Gunnhild Å GÅ; Bjørngaard, Johan H JH; Kinge, Jonas Minet JM; Chen, Yue Y; Mai, Xiao-Mei XM
A high throughput, functional screen of human Body Mass Index GWAS loci using tissue-specific RNAi Drosophila melanogaster crosses.
Plos Genetics
Baranski, Thomas J TJ; Kraja, Aldi T AT; Fink, Jill L JL; Feitosa, Mary M; Lenzini, Petra A PA; Borecki, Ingrid B IB; Liu, Ching-Ti CT; Cupples, L Adrienne LA; North, Kari E KE; Province, Michael A MA
Associations between genetic variants associated with body mass index and trajectories of body fatness across the life course: a longitudinal analysis.
International Journal Of Epidemiology
Song, Mingyang M; Zheng, Yan Y; Qi, Lu L; Hu, Frank B FB; Chan, Andrew T AT; Giovannucci, Edward L EL
Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study.
Plos Medicine
Noyce, Alastair J AJ; Kia, Demis A DA; Hemani, Gibran G; Nicolas, Aude A; Price, T Ryan TR; De Pablo-Fernandez, Eduardo E; Haycock, Philip C PC; Lewis, Patrick A PA; Foltynie, Thomas T; Davey Smith, George G; , ; Schrag, Anette A; Lees, Andrew J AJ; Hardy, John J; Singleton, Andrew A; Nalls, Mike A MA; Pearce, Neil N; Lawlor, Debbie A DA; Wood, Nicholas W NW
Trans-ethnic fine-mapping of genetic loci for body mass index in the diverse ancestral populations of the Population Architecture using Genomics and Epidemiology (PAGE) Study reveals evidence for multiple signals at established loci.
Human Genetics
Fernández-Rhodes, Lindsay L; Gong, Jian J; Haessler, Jeffrey J; Franceschini, Nora N; Graff, Mariaelisa M; Nishimura, Katherine K KK; Wang, Yujie Y; Highland, Heather M HM; Yoneyama, Sachiko S; Bush, William S WS; Goodloe, Robert R; Ritchie, Marylyn D MD; Crawford, Dana D; Gross, Myron M; Fornage, Myriam M; Buzkova, Petra P; Tao, Ran R; Isasi, Carmen C; Avilés-Santa, Larissa L; Daviglus, Martha M; Mackey, Rachel H RH; Houston, Denise D; Gu, C Charles CC; Ehret, Georg G; Nguyen, Khanh-Dung H KH; Lewis, Cora E CE; Leppert, Mark M; Irvin, Marguerite R MR; Lim, Unhee U; Haiman, Christopher A CA; Le Marchand, Loic L; Schumacher, Fredrick F; Wilkens, Lynne L; Lu, Yingchang Y; Bottinger, Erwin P EP; Loos, Ruth J L RJL; Sheu, Wayne H-H WH; Guo, Xiuqing X; Lee, Wen-Jane WJ; Hai, Yang Y; Hung, Yi-Jen YJ; Absher, Devin D; Wu, I-Chien IC; Taylor, Kent D KD; Lee, I-Te IT; Liu, Yeheng Y; Wang, Tzung-Dau TD; Quertermous, Thomas T; Juang, Jyh-Ming J JJ; Rotter, Jerome I JI; Assimes, Themistocles T; Hsiung, Chao A CA; Chen, Yii-Der Ida YI; Prentice, Ross R; Kuller, Lewis H LH; Manson, JoAnn E JE; Kooperberg, Charles C; Smokowski, Paul P; Robinson, Whitney R WR; Gordon-Larsen, Penny P; Li, Rongling R; Hindorff, Lucia L; Buyske, Steven S; Matise, Tara C TC; Peters, Ulrike U; North, Kari E KE
A compendium of human genes regulating feeding behavior and body weight, its functional characterization and identification of GWAS genes involved in brain-specific PPI network.
Bmc Genetics
Ignatieva, Elena V EV; Afonnikov, Dmitry A DA; Saik, Olga V OV; Rogaev, Evgeny I EI; Kolchanov, Nikolay A NA
BMI loci and longitudinal BMI from adolescence to young adulthood in an ethnically diverse cohort.
International Journal Of Obesity (2005)
Graff, M M; North, K E KE; Richardson, A S AS; Young, K L KL; Mazul, A L AL; Highland, H M HM; Mohlke, K L KL; Lange, L A LA; Lange, E M EM; Mullan Harris, K K; Gordon-Larsen, P P
Replication of the Association of BDNF and MC4R Variants With Dietary Intake in the Diabetes Prevention Program.
Psychosomatic Medicine
McCaffery, Jeanne M JM; Jablonski, Kathleen A KA; Franks, Paul W PW; Delahanty, Linda M LM; Aroda, Vanita V; Marrero, David D; Hamman, Richard F RF; Horton, Edward S ES; Dagogo-Jack, Samuel S; Wylie-Rosett, Judith J; Barrett-Connor, Elizabeth E; Kitabchi, Abbas A; Knowler, William C WC; Wing, Rena R RR; Florez, Jose C JC; ,
Evidence for Association between SH2B1 Gene Variants and Glycated Hemoglobin in Nondiabetic European American Young Adults: The Add Health Study.
Annals Of Human Genetics
Lange, Leslie A LA; Graff, Mariaelisa M; Lange, Ethan M EM; Young, Kristin L KL; Richardson, Andrea S AS; Mohlke, Karen L KL; North, Kari E KE; Harris, Kathleen M KM; Gordon-Larsen, Penny P
Classification and Clustering Methods for Multiple Environmental Factors in Gene-Environment Interaction: Application to the Multi-Ethnic Study of Atherosclerosis.
Epidemiology (Cambridge, Mass.)
Ko, Yi-An YA; Mukherjee, Bhramar B; Smith, Jennifer A JA; Kardia, Sharon L R SL; Allison, Matthew M; Diez Roux, Ana V AV
Association of common variants identified by recent genome-wide association studies with obesity in Chinese children: a case-control study.
Bmc Medical Genetics
Wang, Hai-Jun HJ; Hinney, Anke A; Song, Jie-Yun JY; Scherag, André A; Meng, Xiang-Rui XR; Grallert, Harald H; Illig, Thomas T; Hebebrand, Johannes J; Wang, Yan Y; Ma, Jun J
Body Mass Index Genetic Risk Score and Endometrial Cancer Risk.
Plos One
Prescott, Jennifer J; Setiawan, Veronica W VW; Wentzensen, Nicolas N; Schumacher, Fredrick F; Yu, Herbert H; Delahanty, Ryan R; Bernstein, Leslie L; Chanock, Stephen J SJ; Chen, Chu C; Cook, Linda S LS; Friedenreich, Christine C; Garcia-Closas, Monserrat M; Haiman, Christopher A CA; Le Marchand, Loic L; Liang, Xiaolin X; Lissowska, Jolanta J; Lu, Lingeng L; Magliocco, Anthony M AM; Olson, Sara H SH; Risch, Harvey A HA; Shu, Xiao-Ou XO; Ursin, Giske G; Yang, Hannah P HP; Kraft, Peter P; De Vivo, Immaculata I
Epidemiological support for genetic variability at hypothalamic-pituitary-adrenal axis and serotonergic system as risk factors for major depression.
Neuropsychiatric Disease And Treatment
Ching-López, Ana A; Cervilla, Jorge J; Rivera, Margarita M; Molina, Esther E; McKenney, Kathryn K; Ruiz-Perez, Isabel I; Rodríguez-Barranco, Miguel M; Gutiérrez, Blanca B
rs4771122 Predicts Multiple Measures of Long-Term Weight Loss After Bariatric Surgery.
Obesity Surgery
Rasmussen-Torvik, Laura J LJ; Baldridge, Abigail S AS; Pacheco, Jennifer A JA; Aufox, Sharon A SA; Kim, Kwang-Youn A KY; Silverstein, Jonathan C JC; Denham, Erwin W EW; Hungness, Eric E; Smith, Maureen E ME; Greenland, Philip P
Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study.
Plos Medicine
Østergaard, Søren D SD; Mukherjee, Shubhabrata S; Sharp, Stephen J SJ; Proitsi, Petroula P; Lotta, Luca A LA; Day, Felix F; Perry, John R B JR; Boehme, Kevin L KL; Walter, Stefan S; Kauwe, John S JS; Gibbons, Laura E LE; , ; , ; , ; Larson, Eric B EB; Powell, John F JF; Langenberg, Claudia C; Crane, Paul K PK; Wareham, Nicholas J NJ; Scott, Robert A RA
Genetically predicted body mass index and Alzheimer's disease-related phenotypes in three large samples: Mendelian randomization analyses.
Alzheimer'S & Dementia : The Journal Of The Alzheimer'S Association
Mukherjee, Shubhabrata S; Walter, Stefan S; Kauwe, John S K JSK; Saykin, Andrew J AJ; Bennett, David A DA; Larson, Eric B EB; Crane, Paul K PK; Glymour, M Maria MM; , ; , ; ,
Influence of SNP*SNP interaction on BMI in European American adolescents: findings from the National Longitudinal Study of Adolescent Health.
Pediatric Obesity
Young, K L KL; Graff, M M; North, K E KE; Richardson, A S AS; Bradfield, J P JP; Grant, S F A SF; Lange, L A LA; Lange, E M EM; Harris, K M KM; Gordon-Larsen, P P
Genetic studies of body mass index yield new insights for obesity biology.
Nature
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Metabolic signatures of adiposity in young adults: Mendelian randomization analysis and effects of weight change.
Plos Medicine
Würtz, Peter P; Wang, Qin Q; Kangas, Antti J AJ; Richmond, Rebecca C RC; Skarp, Joni J; Tiainen, Mika M; Tynkkynen, Tuulia T; Soininen, Pasi P; Havulinna, Aki S AS; Kaakinen, Marika M; Viikari, Jorma S JS; Savolainen, Markku J MJ; Kähönen, Mika M; Lehtimäki, Terho T; Männistö, Satu S; Blankenberg, Stefan S; Zeller, Tanja T; Laitinen, Jaana J; Pouta, Anneli A; Mäntyselkä, Pekka P; Vanhala, Mauno M; Elliott, Paul P; Pietiläinen, Kirsi H KH; Ripatti, Samuli S; Salomaa, Veikko V; Raitakari, Olli T OT; Järvelin, Marjo-Riitta MR; Smith, George Davey GD; Ala-Korpela, Mika M
Do genetic risk scores for body mass index predict risk of phobic anxiety? Evidence for a shared genetic risk factor.
Psychological Medicine
Walter, S S; Glymour, M M MM; Koenen, K K; Liang, L L; Tchetgen Tchetgen, E J EJ; Cornelis, M M; Chang, S-C SC; Rewak, M M; Rimm, E E; Kawachi, I I; Kubzansky, L D LD
Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty.
Human Molecular Genetics
Cousminer, Diana L DL; Stergiakouli, Evangelia E; Berry, Diane J DJ; Ang, Wei W; Groen-Blokhuis, Maria M MM; Körner, Antje A; Siitonen, Niina N; Ntalla, Ioanna I; Marinelli, Marcella M; Perry, John R B JR; Kettunen, Johannes J; Jansen, Rick R; Surakka, Ida I; Timpson, Nicholas J NJ; Ring, Susan S; Mcmahon, George G; Power, Chris C; Wang, Carol C; Kähönen, Mika M; Viikari, Jorma J; Lehtimäki, Terho T; Middeldorp, Christel M CM; Hulshoff Pol, Hilleke E HE; Neef, Madlen M; Weise, Sebastian S; Pahkala, Katja K; Niinikoski, Harri H; Zeggini, Eleftheria E; Panoutsopoulou, Kalliope K; Bustamante, Mariona M; Penninx, Brenda W J H BW; , ; Murabito, Joanne J; Torrent, Maties M; Dedoussis, George V GV; Kiess, Wieland W; Boomsma, Dorret I DI; Pennell, Craig E CE; Raitakari, Olli T OT; Hyppönen, Elina E; Davey Smith, George G; Ripatti, Samuli S; McCarthy, Mark I MI; Widén, Elisabeth E; ,
Association of a body mass index genetic risk score with growth throughout childhood and adolescence.
Plos One
Warrington, Nicole M NM; Howe, Laura D LD; Wu, Yan Yan YY; Timpson, Nicholas J NJ; Tilling, Kate K; Pennell, Craig E CE; Newnham, John J; Davey-Smith, George G; Palmer, Lyle J LJ; Beilin, Lawrence J LJ; Lye, Stephen J SJ; Lawlor, Debbie A DA; Briollais, Laurent L
Generalization of adiposity genetic loci to US Hispanic women.
Nutrition & Diabetes
Graff, M M; Fernández-Rhodes, L L; Liu, S S; Carlson, C C; Wassertheil-Smoller, S S; Neuhouser, M M; Reiner, A A; Kooperberg, C C; Rampersaud, E E; Manson, J E JE; Kuller, L H LH; Howard, B V BV; Ochs-Balcom, H M HM; Johnson, K C KC; Vitolins, M Z MZ; Sucheston, L L; Monda, K K; North, K E KE
Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course.
Human Molecular Genetics
Graff, Mariaelisa M; Ngwa, Julius S JS; Workalemahu, Tsegaselassie T; Homuth, Georg G; Schipf, Sabine S; Teumer, Alexander A; Völzke, Henry H; Wallaschofski, Henri H; Abecasis, Goncalo R GR; Edward, Lakatta L; Francesco, Cucca C; Sanna, Serena S; Scheet, Paul P; Schlessinger, David D; Sidore, Carlo C; Xiao, Xiangjun X; Wang, Zhaoming Z; Chanock, Stephen J SJ; Jacobs, Kevin B KB; Hayes, Richard B RB; Hu, Frank F; Van Dam, Rob M RM; , ; Crout, Richard J RJ; Marazita, Mary L ML; Shaffer, John R JR; Atwood, Larry D LD; Fox, Caroline S CS; Heard-Costa, Nancy L NL; White, Charles C; Choh, Audrey C AC; Czerwinski, Stefan A SA; Demerath, Ellen W EW; Dyer, Thomas D TD; Towne, Bradford B; Amin, Najaf N; Oostra, Ben A BA; Van Duijn, Cornelia M CM; Zillikens, M Carola MC; Esko, Tõnu T; Nelis, Mari M; Nikopensius, Tit T; Metspalu, Andres A; Strachan, David P DP; Monda, Keri K; Qi, Lu L; North, Kari E KE; Cupples, L Adrienne LA; Gordon-Larsen, Penny P; Berndt, Sonja I SI
Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.
Human Molecular Genetics
Cousminer, Diana L DL; Berry, Diane J DJ; Timpson, Nicholas J NJ; Ang, Wei W; Thiering, Elisabeth E; Byrne, Enda M EM; Taal, H Rob HR; Huikari, Ville V; Bradfield, Jonathan P JP; Kerkhof, Marjan M; Groen-Blokhuis, Maria M MM; Kreiner-Møller, Eskil E; Marinelli, Marcella M; Holst, Claus C; Leinonen, Jaakko T JT; Perry, John R B JR; Surakka, Ida I; Pietiläinen, Olli O; Kettunen, Johannes J; Anttila, Verneri V; Kaakinen, Marika M; Sovio, Ulla U; Pouta, Anneli A; Das, Shikta S; Lagou, Vasiliki V; Power, Chris C; Prokopenko, Inga I; Evans, David M DM; Kemp, John P JP; St Pourcain, Beate B; Ring, Susan S; Palotie, Aarno A; Kajantie, Eero E; Osmond, Clive C; Lehtimäki, Terho T; Viikari, Jorma S JS; Kähönen, Mika M; Warrington, Nicole M NM; Lye, Stephen J SJ; Palmer, Lyle J LJ; Tiesler, Carla M T CM; Flexeder, Claudia C; Montgomery, Grant W GW; Medland, Sarah E SE; Hofman, Albert A; Hakonarson, Hakon H; Guxens, Mònica M; Bartels, Meike M; Salomaa, Veikko V; , ; Murabito, Joanne M JM; Kaprio, Jaakko J; Sørensen, Thorkild I A TI; Ballester, Ferran F; Bisgaard, Hans H; Boomsma, Dorret I DI; Koppelman, Gerard H GH; Grant, Struan F A SF; Jaddoe, Vincent W V VW; Martin, Nicholas G NG; Heinrich, Joachim J; Pennell, Craig E CE; Raitakari, Olli T OT; Eriksson, Johan G JG; Smith, George Davey GD; Hyppönen, Elina E; Järvelin, Marjo-Riitta MR; McCarthy, Mark I MI; Ripatti, Samuli S; Widén, Elisabeth E; ,
Association of cardiovascular and metabolic disease genes with psoriasis.
The Journal Of Investigative Dermatology
Lu, Yingchang Y; Chen, Haoyan H; Nikamo, Pernilla P; Qi Low, Hui H; Helms, Cynthia C; Seielstad, Mark M; Liu, Jianjun J; Bowcock, Anne M AM; Stahle, Mona M; Liao, Wilson W
Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.
Plos Genetics
Fox, Caroline S CS; Liu, Yongmei Y; White, Charles C CC; Feitosa, Mary M; Smith, Albert V AV; Heard-Costa, Nancy N; Lohman, Kurt K; , ; , ; , ; Johnson, Andrew D AD; Foster, Meredith C MC; Greenawalt, Danielle M DM; Griffin, Paula P; Ding, Jinghong J; Newman, Anne B AB; Tylavsky, Fran F; Miljkovic, Iva I; Kritchevsky, Stephen B SB; Launer, Lenore L; Garcia, Melissa M; Eiriksdottir, Gudny G; Carr, J Jeffrey JJ; Gudnason, Vilmunder V; Harris, Tamara B TB; Cupples, L Adrienne LA; Borecki, Ingrid B IB
Genome-wide population-based association study of extremely overweight young adults--the GOYA study.
Plos One
Paternoster, Lavinia L; Evans, David M DM; Nohr, Ellen Aagaard EA; Holst, Claus C; Gaborieau, Valerie V; Brennan, Paul P; Gjesing, Anette Prior AP; Grarup, Niels N; Witte, Daniel R DR; Jørgensen, Torben T; Linneberg, Allan A; Lauritzen, Torsten T; Sandbaek, Anelli A; Hansen, Torben T; Pedersen, Oluf O; Elliott, Katherine S KS; Kemp, John P JP; St Pourcain, Beate B; McMahon, George G; Zelenika, Diana D; Hager, Jörg J; Lathrop, Mark M; Timpson, Nicholas J NJ; Smith, George Davey GD; Sørensen, Thorkild I A TI
Childhood environmental and genetic predictors of adulthood obesity: the cardiovascular risk in young Finns study.
The Journal Of Clinical Endocrinology And Metabolism
Juonala, Markus M; Juhola, Jonna J; Magnussen, Costan G CG; Würtz, Peter P; Viikari, Jorma S A JS; Thomson, Russell R; Seppälä, Ilkka I; Hernesniemi, Jussi J; Kähönen, Mika M; Lehtimäki, Terho T; Hurme, Mikko M; Telama, Risto R; Mikkilä, Vera V; Eklund, Carita C; Räsänen, Leena L; Hintsanen, Mirka M; Keltikangas-Järvinen, Liisa L; Kivimäki, Mika M; Raitakari, Olli T OT