Publications:

---

A frequent SNP in TRIM5α strongly enhances the innate immune response against LINE-1 elements.

Frontiers In Immunology

Lagisquet, Justine J; Conrad, Marcus M; Wittmann, Sabine S; Volkmann, Bianca B; Weissinger, Hannah H; Sticht, Heinrich H; Gramberg, Thomas T

Publication Date: 2023

Variant appearance in text: TRIM5: G249D

PubMed Link: 37180175

Variant Present in the following documents:

• fimmu-14-1168589.pdf

View BVdb publication page

---

Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.

Nature Communications

Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA

Publication Date: 2023-04-03

Variant appearance in text: TRIM5: G249D

PubMed Link: 37012232

Variant Present in the following documents:

• 41467_2023_37547_MOESM12_ESM.xlsx, sheet 2

View BVdb publication page

---

Comprehensive proteogenomic characterization of early duodenal cancer reveals the carcinogenesis tracks of different subtypes.

Nature Communications

Li, Lingling L; Jiang, Dongxian D; Liu, Hui H; Guo, Chunmei C; Zhao, Rui R; Zhang, Qiao Q; Xu, Chen C; Qin, Zhaoyu Z; Feng, Jinwen J; Liu, Yang Y; Wang, Haixing H; Chen, Weijie W; Zhang, Xue X; Li, Bin B; Bai, Lin L; Tian, Sha S; Tan, Subei S; Yu, Zixiang Z; Chen, Lingli L; Huang, Jie J; Zhao, Jian-Yuan JY; Hou, Yingyong Y; Ding, Chen C

Publication Date: 2023-03-29

Variant appearance in text: TRIM5: G249D; rs11038628

PubMed Link: 36991000

Variant Present in the following documents:

• 41467_2023_37221_MOESM5_ESM.xlsx, sheet 3

View BVdb publication page

---

Genetic trajectory and clonal evolution of multiple primary lung cancer with lymph node metastasis.

Cancer Gene Therapy

Tian, He H; Wang, Yalong Y; Yang, Zhenlin Z; Chen, Ping P; Xu, Jiachen J; Tian, Yanhua Y; Fan, Tao T; Xiao, Chu C; Bai, Guangyu G; Li, Lin L; Zheng, Bo B; Li, Chunxiang C; He, Jie J

Publication Date: 2023-01-19

Variant appearance in text: TRIM5: G249D

PubMed Link: 36653483

Variant Present in the following documents:

• 41417_2022_572_MOESM2_ESM.xlsx, sheet 1
• 41417_2022_572_MOESM9_ESM.xlsx, sheet 11

View BVdb publication page

---

Next-generation whole exome sequencing to delineate the genetic basis of primary congenital glaucoma.

Scientific Reports

Rauf, Bushra B; Khan, Shahid Y SY; Jiao, Xiaodong X; Irum, Bushra B; Ashfaq, Ramla R; Zehra, Mubashra M; Khan, Asma A AA; Naeem, Muhammad Asif MA; Shahzad, Mohsin M; Riazuddin, Sheikh S; Hejtmancik, J Fielding JF; Riazuddin, S Amer SA

Publication Date: 2022-10-14

Variant appearance in text: TRIM5: G249D; rs11038628

PubMed Link: 36241656

Variant Present in the following documents:

• 41598_2022_20939_MOESM15_ESM.xlsx, sheet 2

View BVdb publication page

---

A stop-gain mutation in GXYLT1 promotes metastasis of colorectal cancer via the MAPK pathway.

Cell Death & Disease

Peng, Lin L; Zhao, Min M; Liu, Tianqi T; Chen, Jiangbo J; Gao, Pin P; Chen, Lei L; Xing, Pu P; Wang, Zaozao Z; Di, Jiabo J; Xu, Qiang Q; Qu, Hong H; Jiang, Beihai B; Su, Xiangqian X

Publication Date: 2022-04-22

Variant appearance in text: TRIM5: G249D

PubMed Link: 35459861

Variant Present in the following documents:

• 41419_2022_4844_MOESM4_ESM.xlsx, sheet 3

View BVdb publication page

---

Disseminated Talaromyces marneffei Infection in a Non-HIV Infant With a Homozygous Private Variant of RELB.

Frontiers In Cellular And Infection Microbiology

Ding, Xiaofang X; Huang, Han H; Zhong, Lili L; Chen, Min M; Peng, Fang F; Zhang, Bing B; Cui, Xinyu X; Yang, Xiu-An XA

Publication Date: 2021

Variant appearance in text: TRIM5: Gly249Asp; rs11038628

PubMed Link: 33791233

Variant Present in the following documents:

• Table_2.xlsx, sheet 1

View BVdb publication page

---

Human TRIM5α: Autophagy Connects Cell-Intrinsic HIV-1 Restriction and Innate Immune Sensor Functioning.

Viruses

Cloherty, Alexandra P M APM; Rader, Anusca G AG; Compeer, Brandon B; Ribeiro, Carla M S CMS

Publication Date: 2021-02-19

Variant appearance in text: TRIM5: G249D; rs11038628

PubMed Link: 33669846

Variant Present in the following documents:

• Main text
• viruses-13-00320.pdf

View BVdb publication page

---

Identification of a nonsense mutation in TNNI3K associated with cardiac conduction disease.

Journal Of Clinical Laboratory Analysis

Liu, Jiang J; Liu, Da D; Li, Muzheng M; Wu, Keke K; Liu, Na N; Zhao, Chenyu C; Shi, Xiaoliu X; Liu, Qiming Q

Publication Date: 2020-09

Variant appearance in text: TRIM5: G249D; rs11038628

PubMed Link: 32529721

Variant Present in the following documents:

• JCLA-34-e23418-s003.xls, sheet 1

View BVdb publication page

---

Cancer neoantigen prioritization through sensitive and reliable proteogenomics analysis.

Nature Communications

Wen, Bo B; Li, Kai K; Zhang, Yun Y; Zhang, Bing B

Publication Date: 2020-04-09

Variant appearance in text: TRIM5: G249D

PubMed Link: 32273506

Variant Present in the following documents:

• 41467_2020_15456_MOESM6_ESM.xlsx, sheet 1

View BVdb publication page

---

A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma.

Scientific Reports

Stringer, Brett W BW; Day, Bryan W BW; D'Souza, Rochelle C J RCJ; Jamieson, Paul R PR; Ensbey, Kathleen S KS; Bruce, Zara C ZC; Lim, Yi Chieh YC; Goasdoué, Kate K; Offenhäuser, Carolin C; Akgül, Seçkin S; Allan, Suzanne S; Robertson, Thomas T; Lucas, Peter P; Tollesson, Gert G; Campbell, Scott S; Winter, Craig C; Do, Hongdo H; Dobrovic, Alexander A; Inglis, Po-Ling PL; Jeffree, Rosalind L RL; Johns, Terrance G TG; Boyd, Andrew W AW

Publication Date: 2019-03-20

Variant appearance in text: TRIM5: G249D; rs11038628

PubMed Link: 30894629

Variant Present in the following documents:

• 41598_2019_41277_MOESM4_ESM.xlsx, sheet 11
• 41598_2019_41277_MOESM4_ESM.xlsx, sheet 7

View BVdb publication page

---

Defects in assembly explain reduced antiviral activity of the G249D polymorphism in human TRIM5α.

Plos One

Kömürlü, Sevnur S; Bradley, Margret M; Smolin, Nikolai N; Imam, Sabrina S; Pauszek, Raymond F RF; Robia, Seth L SL; Millar, David D; Nakayama, Emi E EE; Shioda, Tatsuo T; Campbell, Edward M EM

Publication Date: 2019

Variant appearance in text: TRIM5: G249D

PubMed Link: 30889178

Variant Present in the following documents:

• Main text
• pone.0212888.pdf

View BVdb publication page

---

Identifying Extrinsic versus Intrinsic Drivers of Variation in Cell Behavior in Human iPSC Lines from Healthy Donors.

Cell Reports

Vigilante, Alessandra A; Laddach, Anna A; Moens, Nathalie N; Meleckyte, Ruta R; Leha, Andreas A; Ghahramani, Arsham A; Culley, Oliver J OJ; Kathuria, Annie A; Hurling, Chloe C; Vickers, Alice A; Wiseman, Erika E; Tewary, Mukul M; Zandstra, Peter W PW; , ; Durbin, Richard R; Fraternali, Franca F; Stegle, Oliver O; Birney, Ewan E; Luscombe, Nicholas M NM; Danovi, Davide D; Watt, Fiona M FM

Publication Date: 2019-02-19

Variant appearance in text: TRIM5: G249D

PubMed Link: 30784590

Variant Present in the following documents:

• mmc6.xlsx, sheet 1

View BVdb publication page

---

Multiple genetic mutations caused by NKX6.3 depletion contribute to gastric tumorigenesis.

Scientific Reports

Yoon, Jung Hwan JH; Kim, Olga O; Eun, Jung Woo JW; Choi, Sung Sook SS; Ashktorab, Hassan H; Smoot, Duane T DT; Nam, Suk Woo SW; Park, Won Sang WS

Publication Date: 2018-12-04

Variant appearance in text: TRIM5: G249D; rs11038628

PubMed Link: 30514953

Variant Present in the following documents:

• 41598_2018_35733_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

---

X-linked ADGRG2 mutation and obstructive azoospermia in a large Pakistani family.

Scientific Reports

Khan, Muhammad Jaseem MJ; Pollock, Nijole N; Jiang, Huaiyang H; Castro, Carlos C; Nazli, Rubina R; Ahmed, Jawad J; Basit, Sulman S; Rajkovic, Aleksandar A; Yatsenko, Alexander N AN

Publication Date: 2018-11-02

Variant appearance in text: TRIM5: G249D; rs11038628

PubMed Link: 30389958

Variant Present in the following documents:

• 41598_2018_34262_MOESM2_ESM.xlsx, sheet 2

View BVdb publication page

---

Targeting TRIM5α in HIV Cure Strategies for the CRISPR-Cas9 Era.

Frontiers In Immunology

Weatherley, Daryl Anne Victoria DAV; Boswell, Michael Terence MT; Rowland-Jones, Sarah L SL

Publication Date: 2017

Variant appearance in text: TRIM5: G249D

PubMed Link: 29213273

Variant Present in the following documents:

• Main text
• fimmu-08-01616.pdf

View BVdb publication page

---

Previously Unidentified Single Nucleotide Polymorphisms in HIV/AIDS Cases Associate with Clinical Parameters and Disease Progression.

Biomed Research International

Anokhin, Vladimir V VV; Bakhteeva, Liliia B LB; Khasanova, Gulshat R GR; Khaiboullina, Svetlana F SF; Martynova, Ekaterina V EV; Tillett, Richard L RL; Schlauch, Karen A KA; Lombardi, Vincent C VC; Rizvanov, Albert A AA

Publication Date: 2016

Variant appearance in text: rs11038628

PubMed Link: 28050553

Variant Present in the following documents:

• Main text
• BMRI2016-2742648.pdf

View BVdb publication page

---

Psoriasis risk SNPs and their association with HIV-1 control.

Human Immunology

Nititham, Joanne J; Gupta, Rashmi R; Zeng, Xue X; Hartogensis, Wendy W; Nixon, Douglas F DF; Deeks, Steven G SG; Hecht, Frederick M FM; Liao, Wilson W

Publication Date: 2017-02

Variant appearance in text: rs11038628

PubMed Link: 27810495

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Reproducible Analysis of Post-Translational Modifications in Proteomes--Application to Human Mutations.

Plos One

Holehouse, Alex S AS; Naegle, Kristen M KM

Publication Date: 2015

Variant appearance in text: rs11038628

PubMed Link: 26659599

Variant Present in the following documents:

• pone.0144692.s002.xlsx, sheet 1

View BVdb publication page

---

Genetic polymorphisms of Trim5a are associated with disease progression in acutely and chronically HIV-infected patients.

International Journal Of Clinical And Experimental Medicine

Sun, Xin X; Li, Wei W; Liu, Wenzhen W; Wang, Rui R; Li, Qunhui Q; Wu, Hao H

Publication Date: 2015

Variant appearance in text: rs11038628

PubMed Link: 26629134

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Impact of TRIM5α in vivo.

Aids (London, England)

Nakayama, Emi E EE; Shioda, Tatsuo T

Publication Date: 2015-09-10

Variant appearance in text: TRIM5: G249D; rs11038628

PubMed Link: 26372380

Variant Present in the following documents:

• Main text
• aids-29-1733.pdf

View BVdb publication page

---

GESPA: classifying nsSNPs to predict disease association.

Bmc Bioinformatics

Khurana, Jay K JK; Reeder, Jay E JE; Shrimpton, Antony E AE; Thakar, Juilee J

Publication Date: 2015-07-25

Variant appearance in text: TRIM5: G249D

PubMed Link: 26206375

Variant Present in the following documents:

• 12859_2015_673_MOESM1_ESM.xls, sheet 2

View BVdb publication page

---

Whole-genome sequencing of the world's oldest people.

Plos One

Gierman, Hinco J HJ; Fortney, Kristen K; Roach, Jared C JC; Coles, Natalie S NS; Li, Hong H; Glusman, Gustavo G; Markov, Glenn J GJ; Smith, Justin D JD; Hood, Leroy L; Coles, L Stephen LS; Kim, Stuart K SK

Publication Date: 2014

Variant appearance in text: TRIM5: G249D; rs11038628

PubMed Link: 25390934

Variant Present in the following documents:

• pone.0112430.s004.xlsx, sheet 1

View BVdb publication page

---

NCI-60 whole exome sequencing and pharmacological CellMiner analyses.

Plos One

Reinhold, William C WC; Varma, Sudhir S; Sousa, Fabricio F; Sunshine, Margot M; Abaan, Ogan D OD; Davis, Sean R SR; Reinhold, Spencer W SW; Kohn, Kurt W KW; Morris, Joel J; Meltzer, Paul S PS; Doroshow, James H JH; Pommier, Yves Y

Publication Date: 2014

Variant appearance in text: TRIM5: G249D; rs11038628

PubMed Link: 25032700

Variant Present in the following documents:

• pone.0101670.s004.xlsx, sheet 1

View BVdb publication page

---

In silico analysis of functional single nucleotide polymorphisms in the human TRIM22 gene.

Plos One

Kelly, Jenna N JN; Barr, Stephen D SD

Publication Date: 2014

Variant appearance in text: TRIM5: G249D

PubMed Link: 24983760

Variant Present in the following documents:

• Main text
• pone.0101436.pdf

View BVdb publication page

---

Integrated mRNA and microRNA transcriptome sequencing characterizes sequence variants and mRNA-microRNA regulatory network in nasopharyngeal carcinoma model systems.

Febs Open Bio

Szeto, Carol Ying-Ying CY; Lin, Chi Ho CH; Choi, Siu Chung SC; Yip, Timothy T C TT; Ngan, Roger Kai-Cheong RK; Tsao, George Sai-Wah GS; Li Lung, Maria M

Publication Date: 2014

Variant appearance in text: TRIM5: G249D; rs11038628

PubMed Link: 24490137

Variant Present in the following documents:

• mmc5.xlsx, sheet 3
• mmc5.xlsx, sheet 2

View BVdb publication page

---

Genomic architecture of HIV-1 infection: current status & challenges.

The Indian Journal Of Medical Research

Kaur, Gurvinder G; Sharma, Gaurav G; Kumar, Neeraj N; Kaul, Mrinali H MH; Bansal, Rhea A RA; Vajpayee, Madhu M; Wig, Naveet N; Sharma, Surender K SK; Mehra, Narinder K NK

Publication Date: 2013-11

Variant appearance in text: rs11038628

PubMed Link: 24434320

Variant Present in the following documents:

• Main text
• IJMR-138-663.pdf

View BVdb publication page

---

Effect of a poly(ADP-ribose) polymerase-1 inhibitor against esophageal squamous cell carcinoma cell lines.

Cancer Science

Nasuno, Tomomitsu T; Mimaki, Sachiyo S; Okamoto, Makito M; Esumi, Hiroyasu H; Tsuchihara, Katsuya K

Publication Date: 2014-02

Variant appearance in text: TRIM5: G249D; rs11038628

PubMed Link: 24219164

Variant Present in the following documents:

• cas0105-0202-SD3.xlsx, sheet 1

View BVdb publication page

---

Restriction genes for retroviruses influence the risk of multiple sclerosis.

Plos One

Nexø, Bjørn A BA; Hansen, Bettina B; Nissen, Kari K KK; Gundestrup, Lisa L; Terkelsen, Thorkild T; Villesen, Palle P; Bahrami, Shervin S; Petersen, Thor T; Pedersen, Finn S FS; Laska, Magdalena J MJ

Publication Date: 2013

Variant appearance in text: rs11038628

PubMed Link: 24066097

Variant Present in the following documents:

• Main text
• pone.0074063.pdf

View BVdb publication page

---

A naturally occurring single amino acid substitution in human TRIM5α linker region affects its anti-HIV type 1 activity and susceptibility to HIV type 1 infection.

Aids Research And Human Retroviruses

Nakayama, Emi E EE; Nakajima, Toshiaki T; Kaur, Gurvinder G; Mimaya, Jun-ich JI; Terunuma, Hiroshi H; Mehra, Narinder N; Kimura, Akinori A; Shioda, Tatsuo T

Publication Date: 2013-06

Variant appearance in text: TRIM5: G249D; rs11038628

PubMed Link: 23379364

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Recent insights into the mechanism and consequences of TRIM5α retroviral restriction.

Aids Research And Human Retroviruses

Sastri, Jaya J; Campbell, Edward M EM

Publication Date: 2011-03

Variant appearance in text: TRIM5: G249D

PubMed Link: 21247355

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Strain-specific differences in the impact of human TRIM5alpha, different TRIM5alpha alleles, and the inhibition of capsid-cyclophilin A interactions on the infectivity of HIV-1.

Journal Of Virology

Battivelli, Emilie E; Lecossier, Denise D; Matsuoka, Saori S; Migraine, Julie J; Clavel, François F; Hance, Allan J AJ

Publication Date: 2010-11

Variant appearance in text: TRIM5: G249D

PubMed Link: 20702630

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Interpreting missense mutations in Human TRIM5alpha by computational methods.

Bmc Research Notes

Chan, Philip A PA

Publication Date: 2008-11-24

Variant appearance in text: TRIM5alpha: G249D

PubMed Link: 19025647

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Role of common human TRIM5alpha variants in HIV-1 disease progression.

Retrovirology

Goldschmidt, Valérie V; Bleiber, Gabriela G; May, Margaret M; Martinez, Raquel R; Ortiz, Millàn M; Telenti, Amalio A; ,

Publication Date: 2006-08-22

Variant appearance in text: TRIM5: G249D; rs11038628

PubMed Link: 16925802

Variant Present in the following documents:

• Main text
• 1742-4690-3-54-S2.pdf
• 1742-4690-3-54-S1.pdf
• 1742-4690-3-54.pdf
• 1742-4690-3-54-S3.pdf

View BVdb publication page

---

A specific region of 37 amino acid residues in the SPRY (B30.2) domain of African green monkey TRIM5alpha determines species-specific restriction of simian immunodeficiency virus SIVmac infection.

Journal Of Virology

Nakayama, Emi E EE; Miyoshi, Hiroyuki H; Nagai, Yoshiyuki Y; Shioda, Tatsuo T

Publication Date: 2005-07

Variant appearance in text: TRIM5: G249D

PubMed Link: 15994780

Variant Present in the following documents:

• Main text

View BVdb publication page

---