Maternal DHA-rich n-3 PUFAs supplementation interacts with FADS genotypes to influence the profiles of PUFAs in the colostrum among Chinese Han population: a birth cohort study.
Investigation of FADS Gene Cluster Single Nucleotide Polymorphisms in End-Stage Renal Disease Compared With Normal Controls.
Frontiers In Genetics
Miladipour, Amirhossein A; Gholipour, Mahdi M; Honarmand Tamizkar, Kasra K; Abak, Atefe A; Kholghi Oskooei, Vahid V; Taheri, Mohammad M; Ghafouri-Fard, Soudeh S
Polygenic risk scores predict diabetes complications and their response to intensive blood pressure and glucose control.
Diabetologia
Tremblay, Johanne J; Haloui, Mounsif M; Attaoua, Redha R; Tahir, Ramzan R; Hishmih, Camil C; Harvey, François F; Marois-Blanchet, François-Christophe FC; Long, Carole C; Simon, Paul P; Santucci, Lara L; Hizel, Candan C; Chalmers, John J; Marre, Michel M; Harrap, Stephen S; Cífková, Renata R; Krajčoviechová, Alena A; Matthews, David R DR; Williams, Bryan B; Poulter, Neil N; Zoungas, Sophia S; Colagiuri, Stephen S; Mancia, Giuseppe G; Grobbee, Diederick E DE; Rodgers, Anthony A; Liu, Liusheng L; Agbessi, Mawussé M; Bruat, Vanessa V; Favé, Marie-Julie MJ; Harwood, Michelle P MP; Awadalla, Philip P; Woodward, Mark M; Hussin, Julie G JG; Hamet, Pavel P
A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis.
Communications Biology
Bell, Steven S; Rigas, Andreas S AS; Magnusson, Magnus K MK; Ferkingstad, Egil E; Allara, Elias E; Bjornsdottir, Gyda G; Ramond, Anna A; Sørensen, Erik E; Halldorsson, Gisli H GH; Paul, Dirk S DS; Burgdorf, Kristoffer S KS; Eggertsson, Hannes P HP; Howson, Joanna M M JMM; Thørner, Lise W LW; Kristmundsdottir, Snaedis S; Astle, William J WJ; Erikstrup, Christian C; Sigurdsson, Jon K JK; Vuckovic, Dragana D; Dinh, Khoa M KM; Tragante, Vinicius V; Surendran, Praveen P; Pedersen, Ole B OB; Vidarsson, Brynjar B; Jiang, Tao T; Paarup, Helene M HM; Onundarson, Pall T PT; Akbari, Parsa P; Nielsen, Kaspar R KR; Lund, Sigrun H SH; Juliusson, Kristinn K; Magnusson, Magnus I MI; Frigge, Michael L ML; Oddsson, Asmundur A; Olafsson, Isleifur I; Kaptoge, Stephen S; Hjalgrim, Henrik H; Runarsson, Gudmundur G; Wood, Angela M AM; Jonsdottir, Ingileif I; Hansen, Thomas F TF; Sigurdardottir, Olof O; Stefansson, Hreinn H; Rye, David D; , ; Peters, James E JE; Westergaard, David D; Holm, Hilma H; Soranzo, Nicole N; Banasik, Karina K; Thorleifsson, Gudmar G; Ouwehand, Willem H WH; Thorsteinsdottir, Unnur U; Roberts, David J DJ; Sulem, Patrick P; Butterworth, Adam S AS; Gudbjartsson, Daniel F DF; Danesh, John J; Brunak, Søren S; Di Angelantonio, Emanuele E; Ullum, Henrik H; Stefansson, Kari K
Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease.
Nature Communications
Nielsen, Jonas B JB; Rom, Oren O; Surakka, Ida I; Graham, Sarah E SE; Zhou, Wei W; Roychowdhury, Tanmoy T; Fritsche, Lars G LG; Gagliano Taliun, Sarah A SA; Sidore, Carlo C; Liu, Yuhao Y; Gabrielsen, Maiken E ME; Skogholt, Anne Heidi AH; Wolford, Brooke B; Overton, William W; Zhao, Ying Y; Chen, Jin J; Zhang, He H; Hornsby, Whitney E WE; Acheampong, Akua A; Grooms, Austen A; Schaefer, Amanda A; Zajac, Gregory J M GJM; Villacorta, Luis L; Zhang, Jifeng J; Brumpton, Ben B; Løset, Mari M; Rai, Vivek V; Lundegaard, Pia R PR; Olesen, Morten S MS; Taylor, Kent D KD; Palmer, Nicholette D ND; Chen, Yii-Der YD; Choi, Seung H SH; Lubitz, Steven A SA; Ellinor, Patrick T PT; Barnes, Kathleen C KC; Daya, Michelle M; Rafaels, Nicholas N; Weiss, Scott T ST; Lasky-Su, Jessica J; Tracy, Russell P RP; Vasan, Ramachandran S RS; Cupples, L Adrienne LA; Mathias, Rasika A RA; Yanek, Lisa R LR; Becker, Lewis C LC; Peyser, Patricia A PA; Bielak, Lawrence F LF; Smith, Jennifer A JA; Aslibekyan, Stella S; Hidalgo, Bertha A BA; Arnett, Donna K DK; Irvin, Marguerite R MR; Wilson, James G JG; Musani, Solomon K SK; Correa, Adolfo A; Rich, Stephen S SS; Guo, Xiuqing X; Rotter, Jerome I JI; Konkle, Barbara A BA; Johnsen, Jill M JM; Ashley-Koch, Allison E AE; Telen, Marilyn J MJ; Sheehan, Vivien A VA; Blangero, John J; Curran, Joanne E JE; Peralta, Juan M JM; Montgomery, Courtney C; Sheu, Wayne H-H WH; Chung, Ren-Hua RH; Schwander, Karen K; Nouraie, Seyed M SM; Gordeuk, Victor R VR; Zhang, Yingze Y; Kooperberg, Charles C; Reiner, Alexander P AP; Jackson, Rebecca D RD; Bleecker, Eugene R ER; Meyers, Deborah A DA; Li, Xingnan X; Das, Sayantan S; Yu, Ketian K; LeFaive, Jonathon J; Smith, Albert A; Blackwell, Tom T; Taliun, Daniel D; Zollner, Sebastian S; Forer, Lukas L; Schoenherr, Sebastian S; Fuchsberger, Christian C; Pandit, Anita A; Zawistowski, Matthew M; Kheterpal, Sachin S; Brummett, Chad M CM; Natarajan, Pradeep P; Schlessinger, David D; Lee, Seunggeun S; Kang, Hyun Min HM; Cucca, Francesco F; Holmen, Oddgeir L OL; Åsvold, Bjørn O BO; Boehnke, Michael M; Kathiresan, Sekar S; Abecasis, Goncalo R GR; Chen, Y Eugene YE; Willer, Cristen J CJ; Hveem, Kristian K
Eicosanoid Inflammatory Mediators Are Robustly Associated With Blood Pressure in the General Population.
Journal Of The American Heart Association
Palmu, Joonatan J; Watrous, Jeramie D JD; Mercader, Kysha K; Havulinna, Aki S AS; Lagerborg, Kim A KA; Salosensaari, Aaro A; Inouye, Mike M; Larson, Martin G MG; Rong, Jian J; Vasan, Ramachandran S RS; Lahti, Leo L; Andres, Allen A; Cheng, Susan S; Jousilahti, Pekka P; Salomaa, Veikko V; Jain, Mohit M; Niiranen, Teemu J TJ
Influence of fatty acid desaturase (FADS) genotype on maternal and child polyunsaturated fatty acids (PUFA) status and child health outcomes: a systematic review.
Nutrition Reviews
Conway, Marie C MC; McSorley, Emeir M EM; Mulhern, Maria S MS; Strain, J J JJ; van Wijngaarden, Edwin E; Yeates, Alison J AJ
Reverse gene-environment interaction approach to identify variants influencing body-mass index in humans.
Nature Metabolism
Garske, Kristina M KM; Pan, David Z DZ; Miao, Zong Z; Bhagat, Yash V YV; Comenho, Caroline C; Robles, Christopher R CR; Benhammou, Jihane N JN; Alvarez, Marcus M; Ko, Arthur A; Ye, Chun Jimmie CJ; Pisegna, Joseph R JR; Mohlke, Karen L KL; Sinsheimer, Janet S JS; Laakso, Markku M; Pajukanta, Päivi P
Association of maternal weight with FADS and ELOVL genetic variants and fatty acid levels- The PREOBE follow-up.
Plos One
de la Garza Puentes, Andrea A; Montes Goyanes, Rosa R; Chisaguano Tonato, Aida Maribel AM; Torres-Espínola, Francisco José FJ; Arias García, Miriam M; de Almeida, Leonor L; Bonilla Aguirre, María M; Guerendiain, Marcela M; Castellote Bargalló, Ana Isabel AI; Segura Moreno, Maite M; García-Valdés, Luz L; Campoy, Cristina C; Lopez-Sabater, M Carmen MC; ,
FADS gene polymorphisms confer the risk of coronary artery disease in a Chinese Han population through the altered desaturase activities: based on high-resolution melting analysis.
Prostatic alpha-linolenic acid (ALA) is positively associated with aggressive prostate cancer: a relationship which may depend on genetic variation in ALA metabolism.
Plos One
Azrad, Maria M; Zhang, Kui K; Vollmer, Robin T RT; Madden, John J; Polascik, Thomas J TJ; Snyder, Denise C DC; Ruffin, Mack T MT; Moul, Judd W JW; Brenner, Dean D; Hardy, Robert W RW; Demark-Wahnefried, Wendy W
FADS genetic variants and omega-6 polyunsaturated fatty acid metabolism in a homogeneous island population.
Journal Of Lipid Research
Mathias, Rasika A RA; Vergara, Candelaria C; Gao, Li L; Rafaels, Nicholas N; Hand, Tracey T; Campbell, Monica M; Bickel, Carol C; Ivester, Priscilla P; Sergeant, Susan S; Barnes, Kathleen C KC; Chilton, Floyd H FH