FADS2 c.208-1740C>T

Variant ID: 11-61603510-C-T

NM_004265.3(FADS2):c.208-1740C>T

This variant was identified in 54 publications

View GRCh38 version.




Publications:


Genetic Influences on the Developing Young Brain and Risk for Neuropsychiatric Disorders.

Biological Psychiatry
Alex, Ann M AM; Buss, Claudia C; Davis, Elysia Poggi EP; Campos, Gustavo de Los GL; Donald, Kirsten A KA; Fair, Damien A DA; Gaab, Nadine N; Gao, Wei W; Gilmore, John H JH; Girault, Jessica B JB; Grewen, Karen K; Groenewold, Nynke A NA; Hankin, Benjamin L BL; Ipser, Jonathan J; Kapoor, Shreya S; Kim, Pilyoung P; Lin, Weili W; Luo, Shan S; Norton, Elizabeth S ES; O'Connor, Thomas G TG; Piven, Joseph J; Qiu, Anqi A; Rasmussen, Jerod M JM; Skeide, Michael A MA; Stein, Dan J DJ; Styner, Martin A MA; Thompson, Paul M PM; Wakschlag, Laurie L; Knickmeyer, Rebecca R; ,
Publication Date: 2023-01-28

Variant appearance in text: rs174576
PubMed Link: 36932005
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Genome-Wide Association Studies and fine-mapping of genomic loci for n-3 and n-6 Polyunsaturated Fatty Acids in Hispanic American and African American Cohorts.

Research Square
Yang, Chaojie C; Veenstra, Jenna J; Bartz, Traci T; Pahl, Matthew M; Hallmark, Brian B; Chen, Yii-Der Ida YI; Westra, Jason J; Steffen, Lyn L; Brown, Christopher C; Siscovick, David D; Tsai, Michael M; Wood, Alexis A; Rich, Stephen S; Smith, Caren C; O'Connor, Timothy T; Mozaffarian, Dariush D; Grant, Struan S; Chilton, Floyd F; Tintle, Nathan N; Lemaitre, Rozenn R; Manichaikul, Ani A
Publication Date: 2023-02-24

Variant appearance in text: rs174576
PubMed Link: 36865120
Variant Present in the following documents:
  • nihpp-rs2073736v1.pdf
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Association of Inherited Genetic Factors With Drug-Induced Hepatic Damage Among Children With Acute Lymphoblastic Leukemia.

Jama Network Open
Yang, Wenjian W; Karol, Seth E SE; Hoshitsuki, Keito K; Lee, Shawn S; Larsen, Eric C EC; Winick, Naomi N; Carroll, William L WL; Loh, Mignon L ML; Raetz, Elizabeth A EA; Hunger, Stephen P SP; Winter, Stuart S SS; Dunsmore, Kimberly P KP; Devidas, Meenakshi M; Relling, Mary V MV; Yang, Jun J JJ
Publication Date: 2022-12-01

Variant appearance in text: rs174576
PubMed Link: 36580335
Variant Present in the following documents:
  • jamanetwopen-e2248803-s001.pdf
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Novel Interactions of Myristic Acid and FADS3 Variants Predict Atopic Dermatitis among Indonesian Infants.

Nutrients
Tanjung, Conny C; Harris, Carla P CP; Demmelmair, Hans H; Dwitya, Sarah S; Munasir, Zakiudin Z; Sudoyo, Herawati H; Standl, Marie M; Sjarif, Damayanti Rusli DR; Koletzko, Berthold B
Publication Date: 2022-11-04

Variant appearance in text: rs174576
PubMed Link: 36364938
Variant Present in the following documents:
  • Main text
  • nutrients-14-04676.pdf
View BVdb publication page



Optimization of Omega-3 Index Levels in Athletes at the US Naval Academy: Personalized Omega-3 Fatty Acid Dosage and Molecular Genetic Approaches.

Nutrients
Rittenhouse, Melissa M; Sambuughin, Nyamkhishig N; Deuster, Patricia P
Publication Date: 2022-07-20

Variant appearance in text: rs174576
PubMed Link: 35889922
Variant Present in the following documents:
  • Main text
  • nutrients-14-02966.pdf
View BVdb publication page



Maternal DHA-rich n-3 PUFAs supplementation interacts with FADS genotypes to influence the profiles of PUFAs in the colostrum among Chinese Han population: a birth cohort study.

Nutrition & Metabolism
Li, Ping P; Chen, Yuhui Y; Song, Jieyun J; Yan, Lailai L; Tang, Tiantian T; Wang, Rui R; Fan, Xiuqin X; Zhao, Yurong Y; Qi, Kemin K
Publication Date: 2022-07-23

Variant appearance in text: rs174576
PubMed Link: 35871074
Variant Present in the following documents:
  • Main text
  • 12986_2022_Article_683.pdf
View BVdb publication page



The impact of fatty acids biosynthesis on the risk of cardiovascular diseases in Europeans and East Asians: a Mendelian randomization study.

Human Molecular Genetics
Borges, Maria-Carolina MC; Haycock, Phillip P; Zheng, Jie J; Hemani, Gibran G; Howe, Laurence J LJ; Schmidt, A Floriaan AF; Staley, James R JR; Lumbers, R Thomas RT; Henry, Albert A; Lemaitre, Rozenn N RN; Gaunt, Tom R TR; Holmes, Michael V MV; Davey Smith, George G; Hingorani, Aroon D AD; Lawlor, Deborah A DA
Publication Date: 2022-11-28

Variant appearance in text: rs174576
PubMed Link: 35796550
Variant Present in the following documents:
  • Main text
  • ddac153.pdf
View BVdb publication page



FADS Polymorphisms Affect the Clinical and Biochemical Phenotypes of Metabolic Syndrome.

Metabolites
Žák, Aleš A; Jáchymová, Marie M; Burda, Michal M; Staňková, Barbora B; Zeman, Miroslav M; Slabý, Adolf A; Vecka, Marek M; Šeda, Ondřej O
Publication Date: 2022-06-20

Variant appearance in text: rs174576
PubMed Link: 35736500
Variant Present in the following documents:
  • Main text
  • metabolites-12-00568.pdf
View BVdb publication page



Altered Cerebral Curvature in Preterm Infants Is Associated with the Common Genetic Variation Related to Autism Spectrum Disorder and Lipid Metabolism.

Journal Of Clinical Medicine
Kim, Hyuna H; Ahn, Ja-Hye JH; Lee, Joo Young JY; Jang, Yong Hun YH; Kim, Young-Eun YE; Kim, Johanna Inhyang JI; Kim, Bung-Nyun BN; Lee, Hyun Ju HJ
Publication Date: 2022-05-31

Variant appearance in text: rs174576
PubMed Link: 35683524
Variant Present in the following documents:
  • Main text
  • jcm-11-03135.pdf
View BVdb publication page



Shared genetic loci between depression and cardiometabolic traits.

Plos Genetics
Torgersen, Kristin K; Rahman, Zillur Z; Bahrami, Shahram S; Hindley, Guy Frederick Lanyon GFL; Parker, Nadine N; Frei, Oleksandr O; Shadrin, Alexey A; O'Connell, Kevin S KS; Tesli, Martin M; Smeland, Olav B OB; Munkhaugen, John J; Djurovic, Srdjan S; Dammen, Toril T; Andreassen, Ole A OA
Publication Date: 2022-05

Variant appearance in text: rs174576
PubMed Link: 35560157
Variant Present in the following documents:
  • Main text
View BVdb publication page



Disentangling Signatures of Selection Before and After European Colonization in Latin Americans.

Molecular Biology And Evolution
Mendoza-Revilla, Javier J; Chacón-Duque, J Camilo JC; Fuentes-Guajardo, Macarena M; Ormond, Louise L; Wang, Ke K; Hurtado, Malena M; Villegas, Valeria V; Granja, Vanessa V; Acuña-Alonzo, Victor V; Jaramillo, Claudia C; Arias, William W; Barquera, Rodrigo R; Gómez-Valdés, Jorge J; Villamil-Ramírez, Hugo H; Silva de Cerqueira, Caio C CC; Badillo Rivera, Keyla M KM; Nieves-Colón, Maria A MA; Gignoux, Christopher R CR; Wojcik, Genevieve L GL; Moreno-Estrada, Andrés A; Hünemeier, Tábita T; Ramallo, Virginia V; Schuler-Faccini, Lavinia L; Gonzalez-José, Rolando R; Bortolini, Maria-Cátira MC; Canizales-Quinteros, Samuel S; Gallo, Carla C; Poletti, Giovanni G; Bedoya, Gabriel G; Rothhammer, Francisco F; Balding, David D; Fumagalli, Matteo M; Adhikari, Kaustubh K; Ruiz-Linares, Andrés A; Hellenthal, Garrett G
Publication Date: 2022-04-11

Variant appearance in text: rs174576
PubMed Link: 35460423
Variant Present in the following documents:
  • Main text
  • msac076.pdf
View BVdb publication page



Nutrigenetics, omega-3 and plasma lipids/lipoproteins/apolipoproteins with evidence evaluation using the GRADE approach: a systematic review.

Bmj Open
Keathley, Justine J; Garneau, Véronique V; Marcil, Valérie V; Mutch, David M DM; Robitaille, Julie J; Rudkowska, Iwona I; Sofian, Gabriela Magdalena GM; Desroches, Sophie S; Vohl, Marie-Claude MC
Publication Date: 2022-02-22

Variant appearance in text: rs174576
PubMed Link: 35193914
Variant Present in the following documents:
  • Main text
  • bmjopen-2021-054417.draft_revisions.pdf
  • bmjopen-2021-054417supp001.pdf
  • bmjopen-2021-054417.pdf
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A multi-omics study of circulating phospholipid markers of blood pressure.

Scientific Reports
Liu, Jun J; de Vries, Paul S PS; Del Greco M, Fabiola F; Johansson, Åsa Å; Schraut, Katharina E KE; Hayward, Caroline C; van Dijk, Ko Willems KW; Franco, Oscar H OH; Hicks, Andrew A AA; Vitart, Veronique V; Rudan, Igor I; Campbell, Harry H; Polašek, Ozren O; Pramstaller, Peter P PP; Wilson, James F JF; Gyllensten, Ulf U; van Duijn, Cornelia M CM; Dehghan, Abbas A; Demirkan, Ayşe A
Publication Date: 2022-01-12

Variant appearance in text: rs174576
PubMed Link: 35022422
Variant Present in the following documents:
  • Main text
  • 41598_2021_Article_4446.pdf
View BVdb publication page



A multi-omics study of circulating phospholipid markers of blood pressure.

Scientific Reports
Liu, Jun J; de Vries, Paul S PS; Del Greco M, Fabiola F; Johansson, Åsa Å; Schraut, Katharina E KE; Hayward, Caroline C; van Dijk, Ko Willems KW; Franco, Oscar H OH; Hicks, Andrew A AA; Vitart, Veronique V; Rudan, Igor I; Campbell, Harry H; Polašek, Ozren O; Pramstaller, Peter P PP; Wilson, James F JF; Gyllensten, Ulf U; van Duijn, Cornelia M CM; Dehghan, Abbas A; Demirkan, Ayşe A
Publication Date: 2022-01-12

Variant appearance in text: rs174576
PubMed Link: 35022422
Variant Present in the following documents:
  • Main text
  • 41598_2021_Article_4446.pdf
View BVdb publication page



Heritability Enrichment of Immunoglobulin G N-Glycosylation in Specific Tissues.

Frontiers In Immunology
Li, Xingang X; Wang, Hao H; Zhu, Yahong Y; Cao, Weijie W; Song, Manshu M; Wang, Youxin Y; Hou, Haifeng H; Lang, Minglin M; Guo, Xiuhua X; Tan, Xuerui X; Han, Jingdong J JJ; Wang, Wei W
Publication Date: 2021

Variant appearance in text: rs174576
PubMed Link: 34804021
Variant Present in the following documents:
  • Main text
  • fimmu-12-741705.pdf
View BVdb publication page



Genetically predicted bipolar disorder is causally associated with an increased risk of breast cancer: a two-sample Mendelian randomization analysis.

Annals Of Translational Medicine
Peng, Haoxin H; Wu, Xiangrong X; Ge, Fan F; Huo, Zhenyu Z; Wen, Yaokai Y; Li, Caichen C; Lin, Jinsheng J; Liang, Hengrui H; Zhong, Ran R; Liu, Jun J; Wang, Runchen R; He, Jianxing J; Liang, Wenhua W
Publication Date: 2021-03

Variant appearance in text: rs174576
PubMed Link: 33842622
Variant Present in the following documents:
  • Main text
  • atm-09-05-401.pdf
View BVdb publication page



Is There a FADS2-Modulated Link between Long-Chain Polyunsaturated Fatty Acids in Plasma Phospholipids and Polyphenol Intake in Adult Subjects Who Are Overweight?

Nutrients
Zec, Manja M MM; Krga, Irena I; Stojković, Ljiljana L; Živković, Maja M; Pokimica, Biljana B; Stanković, Aleksandra A; Glibetic, Maria M
Publication Date: 2021-01-21

Variant appearance in text: rs174576
PubMed Link: 33494132
Variant Present in the following documents:
  • Main text
  • nutrients-13-00296.pdf
View BVdb publication page



Long-Chain Polyunsaturated Fatty Acids, Homocysteine at Birth and Fatty Acid Desaturase Gene Cluster Polymorphisms are Associated with Children's Processing Speed up to Age 9 Years.

Nutrients
Campoy, Cristina C; Azaryah, Hatim H; Torres-Espínola, Francisco J FJ; Martínez-Zaldívar, Cristina C; García-Santos, José Antonio JA; Demmelmair, Hans H; Haile, Gudrun G; Györei, Eszter E; Ramírez-Tortosa, María Del Carmen MDC; Reischl, Eva E; Rzehak, Peter P; Molloy, Anne M AM; Décsi, Tamas T; Luna, Juan de Dios JD; Koletzko, Berthold B; Pérez-García, Miguel M
Publication Date: 2020-12-31

Variant appearance in text: rs174576
PubMed Link: 33396458
Variant Present in the following documents:
  • nutrients-13-00131-s001.pdf
View BVdb publication page



Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease.

Nature Communications
Nielsen, Jonas B JB; Rom, Oren O; Surakka, Ida I; Graham, Sarah E SE; Zhou, Wei W; Roychowdhury, Tanmoy T; Fritsche, Lars G LG; Gagliano Taliun, Sarah A SA; Sidore, Carlo C; Liu, Yuhao Y; Gabrielsen, Maiken E ME; Skogholt, Anne Heidi AH; Wolford, Brooke B; Overton, William W; Zhao, Ying Y; Chen, Jin J; Zhang, He H; Hornsby, Whitney E WE; Acheampong, Akua A; Grooms, Austen A; Schaefer, Amanda A; Zajac, Gregory J M GJM; Villacorta, Luis L; Zhang, Jifeng J; Brumpton, Ben B; Løset, Mari M; Rai, Vivek V; Lundegaard, Pia R PR; Olesen, Morten S MS; Taylor, Kent D KD; Palmer, Nicholette D ND; Chen, Yii-Der YD; Choi, Seung H SH; Lubitz, Steven A SA; Ellinor, Patrick T PT; Barnes, Kathleen C KC; Daya, Michelle M; Rafaels, Nicholas N; Weiss, Scott T ST; Lasky-Su, Jessica J; Tracy, Russell P RP; Vasan, Ramachandran S RS; Cupples, L Adrienne LA; Mathias, Rasika A RA; Yanek, Lisa R LR; Becker, Lewis C LC; Peyser, Patricia A PA; Bielak, Lawrence F LF; Smith, Jennifer A JA; Aslibekyan, Stella S; Hidalgo, Bertha A BA; Arnett, Donna K DK; Irvin, Marguerite R MR; Wilson, James G JG; Musani, Solomon K SK; Correa, Adolfo A; Rich, Stephen S SS; Guo, Xiuqing X; Rotter, Jerome I JI; Konkle, Barbara A BA; Johnsen, Jill M JM; Ashley-Koch, Allison E AE; Telen, Marilyn J MJ; Sheehan, Vivien A VA; Blangero, John J; Curran, Joanne E JE; Peralta, Juan M JM; Montgomery, Courtney C; Sheu, Wayne H-H WH; Chung, Ren-Hua RH; Schwander, Karen K; Nouraie, Seyed M SM; Gordeuk, Victor R VR; Zhang, Yingze Y; Kooperberg, Charles C; Reiner, Alexander P AP; Jackson, Rebecca D RD; Bleecker, Eugene R ER; Meyers, Deborah A DA; Li, Xingnan X; Das, Sayantan S; Yu, Ketian K; LeFaive, Jonathon J; Smith, Albert A; Blackwell, Tom T; Taliun, Daniel D; Zollner, Sebastian S; Forer, Lukas L; Schoenherr, Sebastian S; Fuchsberger, Christian C; Pandit, Anita A; Zawistowski, Matthew M; Kheterpal, Sachin S; Brummett, Chad M CM; Natarajan, Pradeep P; Schlessinger, David D; Lee, Seunggeun S; Kang, Hyun Min HM; Cucca, Francesco F; Holmen, Oddgeir L OL; Åsvold, Bjørn O BO; Boehnke, Michael M; Kathiresan, Sekar S; Abecasis, Goncalo R GR; Chen, Y Eugene YE; Willer, Cristen J CJ; Hveem, Kristian K
Publication Date: 2020-12-18

Variant appearance in text: rs174576
PubMed Link: 33339817
Variant Present in the following documents:
  • 41467_2020_20086_MOESM4_ESM.xlsx, sheet 4
View BVdb publication page



Genome-Wide Association Analysis of Pancreatic Beta-Cell Glucose Sensitivity.

The Journal Of Clinical Endocrinology And Metabolism
Deshmukh, Harshal A HA; Madsen, Anne Lundager AL; Viñuela, Ana A; Have, Christian Theil CT; Grarup, Niels N; Tura, Andrea A; Mahajan, Anubha A; Heggie, Alison J AJ; Koivula, Robert W RW; De Masi, Federico F; Tsirigos, Konstantinos K KK; Linneberg, Allan A; Drivsholm, Thomas T; Pedersen, Oluf O; Sørensen, Thorkild I A TIA; Astrup, Arne A; Gjesing, Anette A P AAP; Pavo, Imre I; Wood, Andrew R AR; Ruetten, Hartmut H; Jones, Angus G AG; Koopman, Anitra D M ADM; Cederberg, Henna H; Rutters, Femke F; Ridderstrale, Martin M; Laakso, Markku M; McCarthy, Mark I MI; Frayling, Tim M TM; Ferrannini, Ele E; Franks, Paul W PW; Pearson, Ewan R ER; Mari, Andrea A; Hansen, Torben T; Walker, Mark M
Publication Date: 2021-01-01

Variant appearance in text: rs174576
PubMed Link: 32944759
Variant Present in the following documents:
  • Main text
View BVdb publication page



Multiomics dissection of molecular regulatory mechanisms underlying autoimmune-associated noncoding SNPs.

Jci Insight
Chen, Xiao-Feng XF; Guo, Ming-Rui MR; Duan, Yuan-Yuan YY; Jiang, Feng F; Wu, Hao H; Dong, Shan-Shan SS; Zhou, Xiao-Rong XR; Thynn, Hlaing Nwe HN; Liu, Cong-Cong CC; Zhang, Lin L; Guo, Yan Y; Yang, Tie-Lin TL
Publication Date: 2020-09-03

Variant appearance in text: rs174576
PubMed Link: 32879140
Variant Present in the following documents:
  • jciinsight-5-136477-s105.xlsx, sheet 5
View BVdb publication page



FADS1 (Fatty Acid Desaturase 1) Genotype Associates With Aortic Valve FADS mRNA Expression, Fatty Acid Content and Calcification.

Circulation. Genomic And Precision Medicine
Plunde, Oscar O; Larsson, Susanna C SC; Artiach, Gonzalo G; Thanassoulis, George G; Carracedo, Miguel M; Franco-Cereceda, Anders A; Eriksson, Per P; Bäck, Magnus M
Publication Date: 2020-06

Variant appearance in text: rs174576
PubMed Link: 32397743
Variant Present in the following documents:
  • Main text
  • hcg-13-e002710-s002.pdf
  • hcg-13-e002710.pdf
View BVdb publication page



Biological Role of Unsaturated Fatty Acid Desaturases in Health and Disease.

Nutrients
Czumaj, Aleksandra A; Śledziński, Tomasz T
Publication Date: 2020-01-29

Variant appearance in text: rs174576
PubMed Link: 32013225
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genome-Wide Association Study for Serum Omega-3 and Omega-6 Polyunsaturated Fatty Acids: Exploratory Analysis of the Sex-Specific Effects and Dietary Modulation in Mediterranean Subjects with Metabolic Syndrome.

Nutrients
Coltell, Oscar O; Sorlí, Jose V JV; Asensio, Eva M EM; Barragán, Rocío R; González, José I JI; Giménez-Alba, Ignacio M IM; Zanón-Moreno, Vicente V; Estruch, Ramon R; Ramírez-Sabio, Judith B JB; Pascual, Eva C EC; Ortega-Azorín, Carolina C; Ordovas, Jose M JM; Corella, Dolores D
Publication Date: 2020-01-24

Variant appearance in text: rs174576
PubMed Link: 31991592
Variant Present in the following documents:
  • Main text
  • nutrients-12-00310-s001.pdf
  • nutrients-12-00310.pdf
View BVdb publication page



Influence of fatty acid desaturase (FADS) genotype on maternal and child polyunsaturated fatty acids (PUFA) status and child health outcomes: a systematic review.

Nutrition Reviews
Conway, Marie C MC; McSorley, Emeir M EM; Mulhern, Maria S MS; Strain, J J JJ; van Wijngaarden, Edwin E; Yeates, Alison J AJ
Publication Date: 2020-08-01

Variant appearance in text: rs174576
PubMed Link: 31943072
Variant Present in the following documents:
  • Main text
View BVdb publication page



Altered polyunsaturated fatty acid levels in relation to proinflammatory cytokines, fatty acid desaturase genotype, and diet in bipolar disorder.

Translational Psychiatry
Koga, Norie N; Ogura, Jun J; Yoshida, Fuyuko F; Hattori, Kotaro K; Hori, Hiroaki H; Aizawa, Emiko E; Ishida, Ikki I; Kunugi, Hiroshi H
Publication Date: 2019-08-27

Variant appearance in text: rs174576
PubMed Link: 31455761
Variant Present in the following documents:
  • Main text
  • 41398_2019_Article_536.pdf
View BVdb publication page



Interaction of Dietary Linoleic Acid and α-Linolenic Acids with rs174547 in FADS1 Gene on Metabolic Syndrome Components among Vegetarians.

Nutrients
Ching, Yuan Kei YK; Chin, Yit Siew YS; Appukutty, Mahenderan M; Ramanchadran, Vasudevan V; Yu, Choo Yee CY; Ang, Geik Yong GY; Gan, Wan Ying WY; Chan, Yoke Mun YM; Teh, Lay Kek LK; Salleh, Mohd Zaki MZ
Publication Date: 2019-07-23

Variant appearance in text: rs174576
PubMed Link: 31340443
Variant Present in the following documents:
  • Main text
  • nutrients-11-01686.pdf
View BVdb publication page



Replicated associations of FADS1, MAD1L1, and a rare variant at 10q26.13 with bipolar disorder in Chinese population.

Translational Psychiatry
Zhao, Lijuan L; Chang, Hong H; Zhou, Dong-Sheng DS; Cai, Jun J; Fan, Weixing W; Tang, Wei W; Tang, Wenxin W; Li, Xingxing X; Liu, Weiqing W; Liu, Fang F; He, Yuanfang Y; Bai, Yan Y; Sun, Yan Y; Dai, Jiapei J; Li, Lingyi L; Xiao, Xiao X; Zhang, Chen C; Li, Ming M
Publication Date: 2018-12-07

Variant appearance in text: rs174576
PubMed Link: 30531795
Variant Present in the following documents:
  • Main text
View BVdb publication page



The association of fatty acid desaturase gene polymorphisms on long-chain polyunsaturated fatty acid composition in Indonesian infants.

The American Journal Of Clinical Nutrition
Tanjung, Conny C; Rzehak, Peter P; Sudoyo, Herawati H; Mansyur, Muchtaruddin M; Munasir, Zakiudin Z; Immanuel, Suzanna S; Irawan, Roedi R; Reischl, Eva E; Demmelmair, Hans H; Hadinegoro, Sri Rezeki SR; Sjarif, Damayanti Rusli DR; Koletzko, Berthold B
Publication Date: 2018-11-01

Variant appearance in text: rs174576
PubMed Link: 30475958
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genes and Dietary Fatty Acids in Regulation of Fatty Acid Composition of Plasma and Erythrocyte Membranes.

Nutrients
Lankinen, Maria M; Uusitupa, Matti M; Schwab, Ursula U
Publication Date: 2018-11-16

Variant appearance in text: rs174576
PubMed Link: 30453550
Variant Present in the following documents:
  • Main text
  • nutrients-10-01785.pdf
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Long-chain polyunsaturated fatty acids, gestation duration, and birth size: a Mendelian randomization study using fatty acid desaturase variants.

The American Journal Of Clinical Nutrition
Bernard, Jonathan Y JY; Pan, Hong H; Aris, Izzuddin M IM; Moreno-Betancur, Margarita M; Soh, Shu-E SE; Yap, Fabian F; Tan, Kok Hian KH; Shek, Lynette P LP; Chong, Yap-Seng YS; Gluckman, Peter D PD; Calder, Philip C PC; Godfrey, Keith M KM; Chong, Mary Foong-Fong MF; Kramer, Michael S MS; Karnani, Neerja N; Lee, Yung Seng YS
Publication Date: 2018-07-01

Variant appearance in text: rs174576
PubMed Link: 29878044
Variant Present in the following documents:
  • Main text
View BVdb publication page



FADS Gene Polymorphisms, Fatty Acid Desaturase Activities, and HDL-C in Type 2 Diabetes.

International Journal Of Environmental Research And Public Health
Huang, Meng-Chuan MC; Chang, Wen-Tsan WT; Chang, Hsin-Yu HY; Chung, Hsin-Fang HF; Chen, Fang-Pei FP; Huang, Ya-Fang YF; Hsu, Chih-Cheng CC; Hwang, Shang-Jyh SJ
Publication Date: 2017-05-28

Variant appearance in text: rs174576
PubMed Link: 28555039
Variant Present in the following documents:
  • Main text
  • ijerph-14-00572.pdf
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Genetically Driven Hyperglycemia Increases Risk of Coronary Artery Disease Separately From Type 2 Diabetes.

Diabetes Care
Merino, Jordi J; Leong, Aaron A; Posner, Daniel C DC; Porneala, Bianca B; Masana, Lluís L; Dupuis, Josée J; Florez, Jose C JC
Publication Date: 2017-05

Variant appearance in text: rs174576
PubMed Link: 28298470
Variant Present in the following documents:
  • Main text
View BVdb publication page



Discovery and fine-mapping of loci associated with MUFAs through trans-ethnic meta-analysis in Chinese and European populations.

Journal Of Lipid Research
Hu, Yao Y; Tanaka, Toshiko T; Zhu, Jingwen J; Guan, Weihua W; Wu, Jason H Y JHY; Psaty, Bruce M BM; McKnight, Barbara B; King, Irena B IB; Sun, Qi Q; Richard, Melissa M; Manichaikul, Ani A; Frazier-Wood, Alexis C AC; Kabagambe, Edmond K EK; Hopkins, Paul N PN; Ordovas, Jose M JM; Ferrucci, Luigi L; Bandinelli, Stefania S; Arnett, Donna K DK; Chen, Yii-Der I YI; Liang, Shuang S; Siscovick, David S DS; Tsai, Michael Y MY; Rich, Stephen S SS; Fornage, Myriam M; Hu, Frank B FB; Rimm, Eric B EB; Jensen, Majken K MK; Lemaitre, Rozenn N RN; Mozaffarian, Dariush D; Steffen, Lyn M LM; Morris, Andrew P AP; Li, Huaixing H; Lin, Xu X
Publication Date: 2017-05

Variant appearance in text: rs174576
PubMed Link: 28298293
Variant Present in the following documents:
  • Main text
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Oxidized Derivatives of Linoleic Acid in Pediatric Metabolic Syndrome: Is Their Pathogenic Role Modulated by the Genetic Background and the Gut Microbiota?

Antioxidants & Redox Signaling
Tricò, Domenico D; Di Sessa, Anna A; Caprio, Sonia S; Chalasani, Naga N; Liu, Wanqing W; Liang, Tiebing T; Graf, Joerg J; Herzog, Raimund I RI; Johnson, Casey D CD; Umano, Giuseppina Rosaria GR; Feldstein, Ariel E AE; Santoro, Nicola N
Publication Date: 2019-01-10

Variant appearance in text: rs174576
PubMed Link: 28279074
Variant Present in the following documents:
  • Main text
View BVdb publication page



Study protocol to investigate the environmental and genetic aetiology of atopic dermatitis: the Indonesian Prospective Study of Atopic Dermatitis in Infants (ISADI).

Bmj Open
Tanjung, Conny C; Rzehak, Peter P; Mansyur, Muchtaruddin M; Munasir, Zakiudin Z; Sudoyo, Herawati H; Immanuel, Suzanna S; Irawan, Roedi R; Reischl, Eva E; Demmelmair, Hans H; Koletzko, Berthold B; Hadinegoro, Sri Rezeki SR; Sjarif, Damayanti Rusli DR
Publication Date: 2017-03-03

Variant appearance in text: rs174576
PubMed Link: 28259851
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  • Main text
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A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorder.

Molecular Psychiatry
Ikeda, M M; Takahashi, A A; Kamatani, Y Y; Okahisa, Y Y; Kunugi, H H; Mori, N N; Sasaki, T T; Ohmori, T T; Okamoto, Y Y; Kawasaki, H H; Shimodera, S S; Kato, T T; Yoneda, H H; Yoshimura, R R; Iyo, M M; Matsuda, K K; Akiyama, M M; Ashikawa, K K; Kashiwase, K K; Tokunaga, K K; Kondo, K K; Saito, T T; Shimasaki, A A; Kawase, K K; Kitajima, T T; Matsuo, K K; Itokawa, M M; Someya, T T; Inada, T T; Hashimoto, R R; Inoue, T T; Akiyama, K K; Tanii, H H; Arai, H H; Kanba, S S; Ozaki, N N; Kusumi, I I; Yoshikawa, T T; Kubo, M M; Iwata, N N
Publication Date: 2018-03

Variant appearance in text: rs174576
PubMed Link: 28115744
Variant Present in the following documents:
  • Main text
  • mp2016259a.pdf
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Integrative Multi-omic Analysis of Human Platelet eQTLs Reveals Alternative Start Site in Mitofusin 2.

American Journal Of Human Genetics
Simon, Lukas M LM; Chen, Edward S ES; Edelstein, Leonard C LC; Kong, Xianguo X; Bhatlekar, Seema S; Rigoutsos, Isidore I; Bray, Paul F PF; Shaw, Chad A CA
Publication Date: 2016-05-05

Variant appearance in text: rs174576
PubMed Link: 27132591
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Maternal single nucleotide polymorphisms in the fatty acid desaturase 1 and 2 coding regions modify the impact of prenatal supplementation with DHA on birth weight.

The American Journal Of Clinical Nutrition
Gonzalez-Casanova, Ines I; Rzehak, Peter P; Stein, Aryeh D AD; Garcia Feregrino, Raquel R; Rivera Dommarco, Juan A JA; Barraza-Villarreal, Albino A; Demmelmair, Hans H; Romieu, Isabelle I; Villalpando, Salvador S; Martorell, Reynaldo R; Koletzko, Berthold B; Ramakrishnan, Usha U
Publication Date: 2016-04

Variant appearance in text: rs174576
PubMed Link: 26912491
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  • Main text
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Animal models of gene-environment interaction in schizophrenia: A dimensional perspective.

Progress In Neurobiology
Ayhan, Yavuz Y; McFarland, Ross R; Pletnikov, Mikhail V MV
Publication Date: 2016-01

Variant appearance in text: rs174576
PubMed Link: 26510407
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  • Main text
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A Mendelian randomization study of the effect of type-2 diabetes on coronary heart disease.

Nature Communications
Ahmad, Omar S OS; Morris, John A JA; Mujammami, Muhammad M; Forgetta, Vincenzo V; Leong, Aaron A; Li, Rui R; Turgeon, Maxime M; Greenwood, Celia M T CM; Thanassoulis, George G; Meigs, James B JB; Sladek, Robert R; Richards, J Brent JB
Publication Date: 2015-05-28

Variant appearance in text: rs174576
PubMed Link: 26017687
Variant Present in the following documents:
  • Main text
  • ncomms8060.pdf
  • ncomms8060-s1.pdf
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Ethnicity, sex, FADS genetic variation, and hormonal contraceptive use influence delta-5- and delta-6-desaturase indices and plasma docosahexaenoic acid concentration in young Canadian adults: a cross-sectional study.

Nutrition & Metabolism
Abdelmagid, Salma A SA; Clarke, Shannon E SE; Roke, Kaitlin K; Nielsen, Daiva E DE; Badawi, Alaa A; El-Sohemy, Ahmed A; Mutch, David M DM; Ma, David Wl DW
Publication Date: 2015

Variant appearance in text: rs174576
PubMed Link: 25914723
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Fatty acid desaturase 1 gene polymorphisms control human hepatic lipid composition.

Hepatology (Baltimore, Md.)
Wang, Libo L; Athinarayanan, Shaminie S; Jiang, Guanglong G; Chalasani, Naga N; Zhang, Min M; Liu, Wanqing W
Publication Date: 2015-01

Variant appearance in text: rs174576
PubMed Link: 25123259
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The role of FADS1/2 polymorphisms on cardiometabolic markers and fatty acid profiles in young adults consuming fish oil supplements.

Nutrients
Roke, Kaitlin K; Mutch, David M DM
Publication Date: 2014-06-16

Variant appearance in text: rs174576
PubMed Link: 24936800
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Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk.

Nature Genetics
Zhang, Ben B; Jia, Wei-Hua WH; Matsuda, Koichi K; Kweon, Sun-Seog SS; Matsuo, Keitaro K; Xiang, Yong-Bing YB; Shin, Aesun A; Jee, Sun Ha SH; Kim, Dong-Hyun DH; Cai, Qiuyin Q; Long, Jirong J; Shi, Jiajun J; Wen, Wanqing W; Yang, Gong G; Zhang, Yanfeng Y; Li, Chun C; Li, Bingshan B; Guo, Yan Y; Ren, Zefang Z; Ji, Bu-Tian BT; Pan, Zhi-Zhong ZZ; Takahashi, Atsushi A; Shin, Min-Ho MH; Matsuda, Fumihiko F; Gao, Yu-Tang YT; Oh, Jae Hwan JH; Kim, Soriul S; Ahn, Yoon-Ok YO; , ; Chan, Andrew T AT; Chang-Claude, Jenny J; Slattery, Martha L ML; , ; Gruber, Stephen B SB; Schumacher, Fredrick R FR; Stenzel, Stephanie L SL; , ; Casey, Graham G; Kim, Hyeong-Rok HR; Jeong, Jin-Young JY; Park, Ji Won JW; Li, Hong-Lan HL; Hosono, Satoyo S; Cho, Sang-Hee SH; Kubo, Michiaki M; Shu, Xiao-Ou XO; Zeng, Yi-Xin YX; Zheng, Wei W
Publication Date: 2014-06

Variant appearance in text: rs174576
PubMed Link: 24836286
Variant Present in the following documents:
  • NIHMS588441-supplement-1.pdf
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FADS2 Genetic Variance in Combination with Fatty Acid Intake Might Alter Composition of the Fatty Acids in Brain.

Plos One
Rizzi, Thais S TS; van der Sluis, Sophie S; Derom, Catherine C; Thiery, Evert E; van Kesteren, Ronald E RE; Jacobs, Nele N; Van Gestel, Sofie S; Vlietinck, Robert R; Verhage, Matthijs M; Heutink, Peter P; Posthuma, Danielle D
Publication Date: 2013

Variant appearance in text: rs174576
PubMed Link: 23826354
Variant Present in the following documents:
  • Main text
  • pone.0068000.pdf
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A genome-wide association study of the human metabolome in a community-based cohort.

Cell Metabolism
Rhee, Eugene P EP; Ho, Jennifer E JE; Chen, Ming-Huei MH; Shen, Dongxiao D; Cheng, Susan S; Larson, Martin G MG; Ghorbani, Anahita A; Shi, Xu X; Helenius, Iiro T IT; O'Donnell, Christopher J CJ; Souza, Amanda L AL; Deik, Amy A; Pierce, Kerry A KA; Bullock, Kevin K; Walford, Geoffrey A GA; Vasan, Ramachandran S RS; Florez, Jose C JC; Clish, Clary C; Yeh, J-R Joanna JR; Wang, Thomas J TJ; Gerszten, Robert E RE
Publication Date: 2013-07-02

Variant appearance in text: rs174576
PubMed Link: 23823483
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Association of polymorphisms in FADS gene with age-related changes in serum phospholipid polyunsaturated fatty acids and oxidative stress markers in middle-aged nonobese men.

Clinical Interventions In Aging
Hong, Seul Hee SH; Kwak, Jung Hyun JH; Paik, Jean Kyung JK; Chae, Jey Sook JS; Lee, Jong Ho JH
Publication Date: 2013

Variant appearance in text: rs174576
PubMed Link: 23818766
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Umbilical cord PUFA are determined by maternal and child fatty acid desaturase (FADS) genetic variants in the Avon Longitudinal Study of Parents and Children (ALSPAC).

The British Journal Of Nutrition
Lattka, Eva E; Koletzko, Berthold B; Zeilinger, Sonja S; Hibbeln, Joseph R JR; Klopp, Norman N; Ring, Susan M SM; Steer, Colin D CD
Publication Date: 2013-04-14

Variant appearance in text: rs174576
PubMed Link: 22877655
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Insertion-deletions in a FADS2 intron 1 conserved regulatory locus control expression of fatty acid desaturases 1 and 2 and modulate response to simvastatin.

Prostaglandins, Leukotrienes, And Essential Fatty Acids
Reardon, Holly T HT; Zhang, Jimmy J; Kothapalli, Kumar S D KS; Kim, Andrea J AJ; Park, Woo Jung WJ; Brenna, J Thomas JT
Publication Date: 2012-07

Variant appearance in text: rs174576
PubMed Link: 22748975
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Variants in CPT1A, FADS1, and FADS2 are Associated with Higher Levels of Estimated Plasma and Erythrocyte Delta-5 Desaturases in Alaskan Eskimos.

Frontiers In Genetics
Voruganti, V Saroja VS; Higgins, Paul B PB; Ebbesson, Sven O E SO; Kennish, John J; Göring, Harald H H HH; Haack, Karin K; Laston, Sandra S; Drigalenko, Eugene E; Wenger, Charlotte R CR; Harris, William S WS; Fabsitz, Richard R RR; Devereux, Richard B RB; Maccluer, Jean W JW; Curran, Joanne E JE; Carless, Melanie A MA; Johnson, Matthew P MP; Moses, Eric K EK; Blangero, John J; Umans, Jason G JG; Howard, Barbara V BV; Cole, Shelley A SA; Comuzzie, Anthony Gean AG
Publication Date: 2012

Variant appearance in text: rs174576
PubMed Link: 22701466
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Differences in arachidonic acid levels and fatty acid desaturase (FADS) gene variants in African Americans and European Americans with diabetes or the metabolic syndrome.

The British Journal Of Nutrition
Sergeant, Susan S; Hugenschmidt, Christina E CE; Rudock, Megan E ME; Ziegler, Julie T JT; Ivester, Priscilla P; Ainsworth, Hannah C HC; Vaidya, Dhananjay D; Case, L Douglas LD; Langefeld, Carl D CD; Freedman, Barry I BI; Bowden, Donald W DW; Mathias, Rasika A RA; Chilton, Floyd H FH
Publication Date: 2012-02

Variant appearance in text: rs174576
PubMed Link: 21733300
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The impact of FADS genetic variants on ω6 polyunsaturated fatty acid metabolism in African Americans.

Bmc Genetics
Mathias, Rasika A RA; Sergeant, Susan S; Ruczinski, Ingo I; Torgerson, Dara G DG; Hugenschmidt, Christina E CE; Kubala, Meghan M; Vaidya, Dhananjay D; Suktitipat, Bhoom B; Ziegler, Julie T JT; Ivester, Priscilla P; Case, Douglas D; Yanek, Lisa R LR; Freedman, Barry I BI; Rudock, Megan E ME; Barnes, Kathleen C KC; Langefeld, Carl D CD; Becker, Lewis C LC; Bowden, Donald W DW; Becker, Diane M DM; Chilton, Floyd H FH
Publication Date: 2011-05-20

Variant appearance in text: rs174576
PubMed Link: 21599946
Variant Present in the following documents:
  • 1471-2156-12-50.pdf
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