FADS3 c.213+2524C>G

Variant ID: 11-61656117-G-C

NM_021727.3(FADS3):c.213+2524C>G

This variant was identified in 25 publications

View GRCh38 version.




Publications:


Novel Interactions of Myristic Acid and FADS3 Variants Predict Atopic Dermatitis among Indonesian Infants.

Nutrients
Tanjung, Conny C; Harris, Carla P CP; Demmelmair, Hans H; Dwitya, Sarah S; Munasir, Zakiudin Z; Sudoyo, Herawati H; Standl, Marie M; Sjarif, Damayanti Rusli DR; Koletzko, Berthold B
Publication Date: 2022-11-04

Variant appearance in text: rs174455
PubMed Link: 36364938
Variant Present in the following documents:
  • nutrients-14-04676.pdf
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Maternal DHA-rich n-3 PUFAs supplementation interacts with FADS genotypes to influence the profiles of PUFAs in the colostrum among Chinese Han population: a birth cohort study.

Nutrition & Metabolism
Li, Ping P; Chen, Yuhui Y; Song, Jieyun J; Yan, Lailai L; Tang, Tiantian T; Wang, Rui R; Fan, Xiuqin X; Zhao, Yurong Y; Qi, Kemin K
Publication Date: 2022-07-23

Variant appearance in text: rs174455
PubMed Link: 35871074
Variant Present in the following documents:
  • Main text
  • 12986_2022_Article_683.pdf
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Long-Chain Polyunsaturated Fatty Acids, Homocysteine at Birth and Fatty Acid Desaturase Gene Cluster Polymorphisms are Associated with Children's Processing Speed up to Age 9 Years.

Nutrients
Campoy, Cristina C; Azaryah, Hatim H; Torres-Espínola, Francisco J FJ; Martínez-Zaldívar, Cristina C; García-Santos, José Antonio JA; Demmelmair, Hans H; Haile, Gudrun G; Györei, Eszter E; Ramírez-Tortosa, María Del Carmen MDC; Reischl, Eva E; Rzehak, Peter P; Molloy, Anne M AM; Décsi, Tamas T; Luna, Juan de Dios JD; Koletzko, Berthold B; Pérez-García, Miguel M
Publication Date: 2020-12-31

Variant appearance in text: rs174455
PubMed Link: 33396458
Variant Present in the following documents:
  • nutrients-13-00131-s001.pdf
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Eicosanoid Inflammatory Mediators Are Robustly Associated With Blood Pressure in the General Population.

Journal Of The American Heart Association
Palmu, Joonatan J; Watrous, Jeramie D JD; Mercader, Kysha K; Havulinna, Aki S AS; Lagerborg, Kim A KA; Salosensaari, Aaro A; Inouye, Mike M; Larson, Martin G MG; Rong, Jian J; Vasan, Ramachandran S RS; Lahti, Leo L; Andres, Allen A; Cheng, Susan S; Jousilahti, Pekka P; Salomaa, Veikko V; Jain, Mohit M; Niiranen, Teemu J TJ
Publication Date: 2020-10-20

Variant appearance in text: rs174455
PubMed Link: 32975162
Variant Present in the following documents:
  • JAH3-9-e017598.pdf
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Genome-Wide Association Study for Serum Omega-3 and Omega-6 Polyunsaturated Fatty Acids: Exploratory Analysis of the Sex-Specific Effects and Dietary Modulation in Mediterranean Subjects with Metabolic Syndrome.

Nutrients
Coltell, Oscar O; Sorlí, Jose V JV; Asensio, Eva M EM; Barragán, Rocío R; González, José I JI; Giménez-Alba, Ignacio M IM; Zanón-Moreno, Vicente V; Estruch, Ramon R; Ramírez-Sabio, Judith B JB; Pascual, Eva C EC; Ortega-Azorín, Carolina C; Ordovas, Jose M JM; Corella, Dolores D
Publication Date: 2020-01-24

Variant appearance in text: rs174455
PubMed Link: 31991592
Variant Present in the following documents:
  • Main text
  • nutrients-12-00310.pdf
  • nutrients-12-00310-s001.pdf
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Influence of fatty acid desaturase (FADS) genotype on maternal and child polyunsaturated fatty acids (PUFA) status and child health outcomes: a systematic review.

Nutrition Reviews
Conway, Marie C MC; McSorley, Emeir M EM; Mulhern, Maria S MS; Strain, J J JJ; van Wijngaarden, Edwin E; Yeates, Alison J AJ
Publication Date: 2020-08-01

Variant appearance in text: rs174455
PubMed Link: 31943072
Variant Present in the following documents:
  • Main text
View BVdb publication page



FADS3 is a Δ14Z sphingoid base desaturase that contributes to gender differences in the human plasma sphingolipidome.

The Journal Of Biological Chemistry
Karsai, Gergely G; Lone, Museer M; Kutalik, Zoltán Z; Brenna, J Thomas JT; Li, Hongde H; Pan, Duojia D; von Eckardstein, Arnold A; Hornemann, Thorsten T
Publication Date: 2020-02-14

Variant appearance in text: rs174455
PubMed Link: 31862735
Variant Present in the following documents:
  • Main text
  • zbc1889.pdf
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Determinants of Plasma Docosahexaenoic Acid Levels and Their Relationship to Neurological and Cognitive Functions in PKU Patients: A Double Blind Randomized Supplementation Study.

Nutrients
Demmelmair, Hans H; MacDonald, Anita A; Kotzaeridou, Urania U; Burgard, Peter P; Gonzalez-Lamuno, Domingo D; Verduci, Elvira E; Ersoy, Melike M; Gokcay, Gulden G; Alyanak, Behiye B; Reischl, Eva E; Müller-Felber, Wolfgang W; Faber, Fabienne Lara FL; Handel, Uschi U; Paci, Sabrina S; Koletzko, Berthold B
Publication Date: 2018-12-07

Variant appearance in text: rs174455
PubMed Link: 30544518
Variant Present in the following documents:
  • Main text
View BVdb publication page



The association of fatty acid desaturase gene polymorphisms on long-chain polyunsaturated fatty acid composition in Indonesian infants.

The American Journal Of Clinical Nutrition
Tanjung, Conny C; Rzehak, Peter P; Sudoyo, Herawati H; Mansyur, Muchtaruddin M; Munasir, Zakiudin Z; Immanuel, Suzanna S; Irawan, Roedi R; Reischl, Eva E; Demmelmair, Hans H; Hadinegoro, Sri Rezeki SR; Sjarif, Damayanti Rusli DR; Koletzko, Berthold B
Publication Date: 2018-11-01

Variant appearance in text: rs174455
PubMed Link: 30475958
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genes and Dietary Fatty Acids in Regulation of Fatty Acid Composition of Plasma and Erythrocyte Membranes.

Nutrients
Lankinen, Maria M; Uusitupa, Matti M; Schwab, Ursula U
Publication Date: 2018-11-16

Variant appearance in text: rs174455
PubMed Link: 30453550
Variant Present in the following documents:
  • Main text
  • nutrients-10-01785.pdf
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Long-chain polyunsaturated fatty acids, gestation duration, and birth size: a Mendelian randomization study using fatty acid desaturase variants.

The American Journal Of Clinical Nutrition
Bernard, Jonathan Y JY; Pan, Hong H; Aris, Izzuddin M IM; Moreno-Betancur, Margarita M; Soh, Shu-E SE; Yap, Fabian F; Tan, Kok Hian KH; Shek, Lynette P LP; Chong, Yap-Seng YS; Gluckman, Peter D PD; Calder, Philip C PC; Godfrey, Keith M KM; Chong, Mary Foong-Fong MF; Kramer, Michael S MS; Karnani, Neerja N; Lee, Yung Seng YS
Publication Date: 2018-07-01

Variant appearance in text: rs174455
PubMed Link: 29878044
Variant Present in the following documents:
  • Main text
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Fads3 modulates docosahexaenoic acid in liver and brain.

Prostaglandins, Leukotrienes, And Essential Fatty Acids
Zhang, Ji Yao JY; Qin, Xia X; Liang, Allison A; Kim, Ellen E; Lawrence, Peter P; Park, Woo Jung WJ; Kothapalli, Kumar S D KSD; Brenna, J Thomas JT
Publication Date: 2017-08

Variant appearance in text: rs174455
PubMed Link: 28838557
Variant Present in the following documents:
  • Main text
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Selection in Europeans on Fatty Acid Desaturases Associated with Dietary Changes.

Molecular Biology And Evolution
Buckley, Matthew T MT; Racimo, Fernando F; Allentoft, Morten E ME; Jensen, Majken K MK; Jonsson, Anna A; Huang, Hongyan H; Hormozdiari, Farhad F; Sikora, Martin M; Marnetto, Davide D; Eskin, Eleazar E; Jørgensen, Marit E ME; Grarup, Niels N; Pedersen, Oluf O; Hansen, Torben T; Kraft, Peter P; Willerslev, Eske E; Nielsen, Rasmus R
Publication Date: 2017-06-01

Variant appearance in text: rs174455
PubMed Link: 28333262
Variant Present in the following documents:
  • Main text
View BVdb publication page



Study protocol to investigate the environmental and genetic aetiology of atopic dermatitis: the Indonesian Prospective Study of Atopic Dermatitis in Infants (ISADI).

Bmj Open
Tanjung, Conny C; Rzehak, Peter P; Mansyur, Muchtaruddin M; Munasir, Zakiudin Z; Sudoyo, Herawati H; Immanuel, Suzanna S; Irawan, Roedi R; Reischl, Eva E; Demmelmair, Hans H; Koletzko, Berthold B; Hadinegoro, Sri Rezeki SR; Sjarif, Damayanti Rusli DR
Publication Date: 2017-03-03

Variant appearance in text: rs174455
PubMed Link: 28259851
Variant Present in the following documents:
  • Main text
  • bmjopen-2016-012475.pdf
View BVdb publication page



Alternative splicing generates novel Fads3 transcript in mice.

Molecular Biology Reports
Zhang, Ji Yao JY; Qin, Xia X; Park, Hui Gyu HG; Kim, Ellen E; Liu, Guowen G; Kothapalli, Kumar S D KSD; Brenna, J Thomas JT
Publication Date: 2016-08

Variant appearance in text: rs174455
PubMed Link: 27216536
Variant Present in the following documents:
  • Main text
View BVdb publication page



Maternal single nucleotide polymorphisms in the fatty acid desaturase 1 and 2 coding regions modify the impact of prenatal supplementation with DHA on birth weight.

The American Journal Of Clinical Nutrition
Gonzalez-Casanova, Ines I; Rzehak, Peter P; Stein, Aryeh D AD; Garcia Feregrino, Raquel R; Rivera Dommarco, Juan A JA; Barraza-Villarreal, Albino A; Demmelmair, Hans H; Romieu, Isabelle I; Villalpando, Salvador S; Martorell, Reynaldo R; Koletzko, Berthold B; Ramakrishnan, Usha U
Publication Date: 2016-04

Variant appearance in text: rs174455
PubMed Link: 26912491
Variant Present in the following documents:
  • Main text
View BVdb publication page



Desaturase and elongase-limiting endogenous long-chain polyunsaturated fatty acid biosynthesis.

Current Opinion In Clinical Nutrition And Metabolic Care
Zhang, Ji Yao JY; Kothapalli, Kumar S D KS; Brenna, J Thomas JT
Publication Date: 2016-03

Variant appearance in text: rs174455
PubMed Link: 26828581
Variant Present in the following documents:
  • Main text
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Maternal fatty acids in pregnancy, FADS polymorphisms, and child intelligence quotient at 8 y of age.

The American Journal Of Clinical Nutrition
Steer, Colin D CD; Lattka, Eva E; Koletzko, Berthold B; Golding, Jean J; Hibbeln, Joseph R JR
Publication Date: 2013-12

Variant appearance in text: rs174455
PubMed Link: 24067669
Variant Present in the following documents:
  • Main text
View BVdb publication page



FADS2 Genetic Variance in Combination with Fatty Acid Intake Might Alter Composition of the Fatty Acids in Brain.

Plos One
Rizzi, Thais S TS; van der Sluis, Sophie S; Derom, Catherine C; Thiery, Evert E; van Kesteren, Ronald E RE; Jacobs, Nele N; Van Gestel, Sofie S; Vlietinck, Robert R; Verhage, Matthijs M; Heutink, Peter P; Posthuma, Danielle D
Publication Date: 2013

Variant appearance in text: rs174455
PubMed Link: 23826354
Variant Present in the following documents:
  • Main text
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Do ω-3 or other fatty acids influence the development of 'growing pains'? A prebirth cohort study.

Bmj Open
Golding, Jean J; Northstone, Kate K; Emmett, Pauline P; Steer, Colin C; Hibbeln, Joseph R JR
Publication Date: 2012

Variant appearance in text: rs174455
PubMed Link: 22923631
Variant Present in the following documents:
  • Main text
  • bmjopen-2012-001370.draft_revisions.pdf
  • bmjopen-2012-001370.pdf
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Umbilical cord PUFA are determined by maternal and child fatty acid desaturase (FADS) genetic variants in the Avon Longitudinal Study of Parents and Children (ALSPAC).

The British Journal Of Nutrition
Lattka, Eva E; Koletzko, Berthold B; Zeilinger, Sonja S; Hibbeln, Joseph R JR; Klopp, Norman N; Ring, Susan M SM; Steer, Colin D CD
Publication Date: 2013-04-14

Variant appearance in text: rs174455
PubMed Link: 22877655
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic variation in polyunsaturated fatty acid metabolism and its potential relevance for human development and health.

Maternal & Child Nutrition
Glaser, Claudia C; Lattka, Eva E; Rzehak, Peter P; Steer, Colin C; Koletzko, Berthold B
Publication Date: 2011-04

Variant appearance in text: rs174455
PubMed Link: 21366865
Variant Present in the following documents:
  • Main text
View BVdb publication page



The ATXN1 and TRIM31 genes are related to intelligence in an ADHD background: evidence from a large collaborative study totaling 4,963 subjects.

American Journal Of Medical Genetics. Part B, Neuropsychiatric Genetics : The Official Publication Of The International Society Of Psychiatric Genetics
Rizzi, Thais S TS; Arias-Vasquez, Alejandro A; Rommelse, Nanda N; Kuntsi, Jonna J; Anney, Richard R; Asherson, Philip P; Buitelaar, Jan J; Banaschewski, Tobias T; Ebstein, Richard R; Ruano, Dina D; Van der Sluis, Sophie S; Markunas, Christina A CA; Garrett, Melanie E ME; Ashley-Koch, Allison E AE; Kollins, Scott H SH; Anastopoulos, Arthur D AD; Hansell, Narelle K NK; Wright, Margaret J MJ; Montgomery, Grant W GW; Martin, Nicholas G NG; Harris, Sarah E SE; Davies, Gail G; Tenesa, Albert A; Porteous, David J DJ; Starr, John M JM; Deary, Ian J IJ; St Pourcain, Beate B; Davey Smith, George G; Timpson, Nicholas J NJ; Evans, David M DM; Gill, Michael M; Miranda, Ana A; Mulas, Fernando F; Oades, Robert D RD; Roeyers, Herbert H; Rothenberger, Aribert A; Sergeant, Joseph J; Sonuga-Barke, Edmund E; Steinhausen, Hans Christoph HC; Taylor, Eric E; Faraone, Stephen V SV; Franke, Barbara B; Posthuma, Danielle D
Publication Date: 2011-03

Variant appearance in text: rs174455
PubMed Link: 21302343
Variant Present in the following documents:
  • Main text
  • ajmg0156-0145.pdf
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Genome-wide quantitative trait locus association scan of general cognitive ability using pooled DNA and 500K single nucleotide polymorphism microarrays.

Genes, Brain, And Behavior
Butcher, L M LM; Davis, O S P OS; Craig, I W IW; Plomin, R R
Publication Date: 2008-06

Variant appearance in text: rs174455
PubMed Link: 18067574
Variant Present in the following documents:
  • Main text
  • gbb0007-0435.pdf
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