SLC22A6 c.149G>T ;(p.R50L)

Variant ID: 11-62752014-C-A

NM_153276.2(SLC22A6):c.149G>T;(p.R50L)

This variant was identified in 14 publications

View GRCh38 version.




Publications:


Pharmacogenetics of tenofovir renal toxicity in HIV-positive Southern Africans.

Pharmacogenetics And Genomics
Mateza, Somila S; Bradford, Yuki Y; Maartens, Gary G; Sokhela, Simiso S; Chandiwana, Nomathemba C NC; Venter, Willem D F WDF; Post, Frank A FA; Ritchie, Marylyn D MD; Haas, David W DW; Sinxadi, Phumla P
Publication Date: 2023-04-24

Variant appearance in text: rs11568626
PubMed Link: 37099271
Variant Present in the following documents:
  • Main text
  • pgen-33-91.pdf
View BVdb publication page



Influence of UGT1A1 and SLC22A6 polymorphisms on the population pharmacokinetics and pharmacodynamics of raltegravir in HIV-infected adults: a NEAT001/ANRS143 sub-study.

The Pharmacogenomics Journal
Gurjar, Rohan R; Dickinson, Laura L; Carr, Daniel D; Stöhr, Wolfgang W; Bonora, Stefano S; Owen, Andrew A; D'Avolio, Antonio A; Cursley, Adam A; De Castro, Nathalie N; Fätkenheuer, Gerd G; Vandekerckhove, Linos L; Di Perri, Giovanni G; Pozniak, Anton A; Schwimmer, Christine C; Raffi, François F; Boffito, Marta M; ,
Publication Date: 2022-10-20

Variant appearance in text: rs11568626
PubMed Link: 36266537
Variant Present in the following documents:
  • Main text
  • 41397_2022_Article_293.pdf
View BVdb publication page



Design and methods of the prevalence and pharmacogenomics of tenofovir nephrotoxicity in HIV-positive adults in south-western Nigeria study.

Bmc Nephrology
Hassan, Muzamil O MO; Duarte, Raquel R; Mabayoje, Victor O VO; Dickens, Caroline C; Lasisi, Akeem O AO; Naicker, Saraladevi S
Publication Date: 2020-10-16

Variant appearance in text: rs11568626
PubMed Link: 33066744
Variant Present in the following documents:
  • Main text
  • 12882_2020_Article_2082.pdf
View BVdb publication page



South-south collaboration on HIV/AIDS prevention and treatment research: when birds of a feather rarely flock together.

Globalization And Health
Fonseca, Bruna de Paula Fonseca E BPFE; Albuquerque, Priscila Costa PC; Noyons, Ed E; Zicker, Fabio F
Publication Date: 2018-03-01

Variant appearance in text: rs11568626
PubMed Link: 29490665
Variant Present in the following documents:
  • 12992_2018_341_MOESM1_ESM.xlsx, sheet 1
View BVdb publication page



Genetic variation in human drug-related genes.

Genome Medicine
Schärfe, Charlotta Pauline Irmgard CPI; Tremmel, Roman R; Schwab, Matthias M; Kohlbacher, Oliver O; Marks, Debora Susan DS
Publication Date: 2017-12-22

Variant appearance in text: rs11568626
PubMed Link: 29273096
Variant Present in the following documents:
  • 13073_2017_502_MOESM2_ESM.xlsx, sheet 2
View BVdb publication page



Clinical Implementation of Pharmacogenetic Testing in a Hospital of the Spanish National Health System: Strategy and Experience Over 3 Years.

Clinical And Translational Science
Borobia, Alberto M AM; Dapia, Irene I; Tong, Hoi Y HY; Arias, Pedro P; Muñoz, Mario M; Tenorio, Jair J; Hernández, Rafael R; García García, Irene I; Gordo, Gema G; Ramírez, Elena E; Frías, Jesús J; Lapunzina, Pablo P; Carcas, Antonio J AJ
Publication Date: 2018-03

Variant appearance in text: rs11568626
PubMed Link: 29193749
Variant Present in the following documents:
  • Main text
  • CTS-11-189.pdf
View BVdb publication page



Characterization of ADME gene variation in 21 populations by exome sequencing.

Pharmacogenetics And Genomics
Hovelson, Daniel H DH; Xue, Zhengyu Z; Zawistowski, Matthew M; Ehm, Margaret G MG; Harris, Elizabeth C EC; Stocker, Sophie L SL; Gross, Annette S AS; Jang, In-Jin IJ; Ieiri, Ichiro I; Lee, Jong-Eun JE; Cardon, Lon R LR; Chissoe, Stephanie L SL; Abecasis, Gonçalo G; Nelson, Matthew R MR
Publication Date: 2017-03

Variant appearance in text: rs11568626
PubMed Link: 27984508
Variant Present in the following documents:
  • fpc-27-089-s005.xlsx, sheet 2
View BVdb publication page



Molecular analysis of urothelial cancer cell lines for modeling tumor biology and drug response.

Oncogene
Nickerson, M L ML; Witte, N N; Im, K M KM; Turan, S S; Owens, C C; Misner, K K; Tsang, S X SX; Cai, Z Z; Wu, S S; Dean, M M; Costello, J C JC; Theodorescu, D D
Publication Date: 2017-01-05

Variant appearance in text: rs11568626
PubMed Link: 27270441
Variant Present in the following documents:
  • onc2016172x3.xls, sheet 3
View BVdb publication page



Polymorphisms in genes involved in the absorption, distribution, metabolism, and excretion of drugs in the Kazakhs of Kazakhstan.

Bmc Genetics
Iskakova, Aisha N AN; Romanova, Aliya A AA; Aitkulova, Akbota M AM; Sikhayeva, Nurgul S NS; Zholdybayeva, Elena V EV; Ramanculov, Erlan M EM
Publication Date: 2016-01-19

Variant appearance in text: rs11568626
PubMed Link: 26785747
Variant Present in the following documents:
View BVdb publication page



Pharmacogenomics of Methotrexate Membrane Transport Pathway: Can Clinical Response to Methotrexate in Rheumatoid Arthritis Be Predicted?

International Journal Of Molecular Sciences
Lima, Aurea A; Bernardes, Miguel M; Azevedo, Rita R; Medeiros, Rui R; Seabra, Vítor V
Publication Date: 2015-06-16

Variant appearance in text: rs11568626
PubMed Link: 26086825
Variant Present in the following documents:
  • Main text
  • ijms-16-13760.pdf
View BVdb publication page



The Affymetrix DMET Plus platform reveals unique distribution of ADME-related variants in ethnic Arabs.

Disease Markers
Wakil, Salma M SM; Nguyen, Cao C; Muiya, Nzioka P NP; Andres, Editha E; Lykowska-Tarnowska, Agnieszka A; Baz, Batoul B; Tahir, Asma I AI; Meyer, Brian F BF; Morahan, Grant G; Dzimiri, Nduna N
Publication Date: 2015

Variant appearance in text: rs11568626
PubMed Link: 25802476
Variant Present in the following documents:
  • 542543.f1.xlsx, sheet 1
View BVdb publication page



The role of drug transporters in the kidney: lessons from tenofovir.

Frontiers In Pharmacology
Moss, Darren M DM; Neary, Megan M; Owen, Andrew A
Publication Date: 2014

Variant appearance in text: rs11568626
PubMed Link: 25426075
Variant Present in the following documents:
  • Main text
  • fphar-05-00248.pdf
View BVdb publication page



The RPTEC/TERT1 cell line models key renal cell responses to the environmental toxicants, benzo[a]pyrene and cadmium.

Toxicology Reports
Simon, B R BR; Wilson, M J MJ; Wickliffe, J K JK
Publication Date: 2014

Variant appearance in text: rs11568626
PubMed Link: 25126521
Variant Present in the following documents:
  • mmc1.xls, sheet 1
View BVdb publication page



Polymorphisms in genes encoding potential mercury transporters and urine mercury concentrations in populations exposed to mercury vapor from gold mining.

Environmental Health Perspectives
Engström, Karin K; Ameer, Shegufta S; Bernaudat, Ludovic L; Drasch, Gustav G; Baeuml, Jennifer J; Skerfving, Staffan S; Bose-O'Reilly, Stephan S; Broberg, Karin K
Publication Date: 2013-01

Variant appearance in text: rs11568626
PubMed Link: 23052037
Variant Present in the following documents:
  • Main text
  • ehp.1204951.pdf
View BVdb publication page