Publications:

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The impact of genetic variability in urate transporters on oxypurinol pharmacokinetics.

Clinical And Translational Science

Hishe, Hailemichael Z HZ; Stocker, Sophie L SL; Stamp, Lisa K LK; Dalbeth, Nicola N; Merriman, Tony R TR; Phipps-Green, Amanda A; Wright, Daniel F B DFB

Publication Date: 2022-11-17

Variant appearance in text: rs17300741

PubMed Link: 36398357

Variant Present in the following documents:

• Main text
• CTS-16-422.pdf

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Susceptibility genes of hyperuricemia and gout.

Hereditas

Nian, Yue-Li YL; You, Chong-Ge CG

Publication Date: 2022-08-04

Variant appearance in text: rs17300741

PubMed Link: 35922835

Variant Present in the following documents:

• Main text
• 41065_2022_Article_243.pdf

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Genetic assessment of hyperuricemia and gout in Asian, Native Hawaiian, and Pacific Islander subgroups of pregnant women: biospecimens repository cross-sectional study.

Bmc Rheumatology

Alghubayshi, Ali A; Edelman, Alison A; Alrajeh, Khalifa K; Roman, Youssef Y

Publication Date: 2022-01-06

Variant appearance in text: rs17300741

PubMed Link: 34986901

Variant Present in the following documents:

• Main text
• 41927_2021_Article_239.pdf

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Genetic assessment of hyperuricemia and gout in Asian, Native Hawaiian, and Pacific Islander subgroups of pregnant women: biospecimens repository cross-sectional study.

Bmc Rheumatology

Alghubayshi, Ali A; Edelman, Alison A; Alrajeh, Khalifa K; Roman, Youssef Y

Publication Date: 2022-01-06

Variant appearance in text: rs17300741

PubMed Link: 34986901

Variant Present in the following documents:

• Main text
• 41927_2021_Article_239.pdf

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Function of Uric Acid Transporters and Their Inhibitors in Hyperuricaemia.

Frontiers In Pharmacology

Sun, Hao-Lu HL; Wu, Yi-Wan YW; Bian, He-Ge HG; Yang, Hui H; Wang, Heng H; Meng, Xiao-Ming XM; Jin, Juan J

Publication Date: 2021

Variant appearance in text: rs17300741

PubMed Link: 34335246

Variant Present in the following documents:

• Main text

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Urate Transporters in the Kidney: What Clinicians Need to Know.

Electrolyte & Blood Pressure : E & Bp

Chung, Sungjin S; Kim, Gheun-Ho GH

Publication Date: 2021-06

Variant appearance in text: rs17300741

PubMed Link: 34290818

Variant Present in the following documents:

• Main text
• ebp-19-1.pdf

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Modulation of Urate Transport by Drugs.

Pharmaceutics

Tátrai, Péter P; Erdő, Franciska F; Dörnyei, Gabriella G; Krajcsi, Péter P

Publication Date: 2021-06-17

Variant appearance in text: rs17300741

PubMed Link: 34204277

Variant Present in the following documents:

• Main text
• pharmaceutics-13-00899.pdf

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Mendelian randomization study shows no causal effects of serum urate levels on the risk of MS.

Neurology(R) Neuroimmunology & Neuroinflammation

Harroud, Adil A; Richards, J Brent JB; Baranzini, Sergio E SE

Publication Date: 2021-01

Variant appearance in text: rs17300741

PubMed Link: 33214142

Variant Present in the following documents:

• NEURIMMINFL2020030502.pdf

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Sex Differences in Urate Handling.

International Journal Of Molecular Sciences

Halperin Kuhns, Victoria L VL; Woodward, Owen M OM

Publication Date: 2020-06-16

Variant appearance in text: rs17300741

PubMed Link: 32560040

Variant Present in the following documents:

• Main text
• ijms-21-04269.pdf

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Mendelian randomization study of serum uric acid levels and diabetes risk: evidence from the Dongfeng-Tongji cohort.

Bmj Open Diabetes Research & Care

Keerman, Mulatibieke M; Yang, Fen F; Hu, Hua H; Wang, Jing J; Wang, Fei F; Li, Zhaoyang Z; Yuan, Jing J; Yao, Ping P; Zhang, Xiaomin X; Guo, Huan H; Yang, Handong H; He, Meian M

Publication Date: 2020-02

Variant appearance in text: rs17300741

PubMed Link: 32111716

Variant Present in the following documents:

• bmjdrc-2019-000834supp001.pdf

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Improving the odds of drug development success through human genomics: modelling study.

Scientific Reports

Hingorani, Aroon D AD; Kuan, Valerie V; Finan, Chris C; Kruger, Felix A FA; Gaulton, Anna A; Chopade, Sandesh S; Sofat, Reecha R; MacAllister, Raymond J RJ; Overington, John P JP; Hemingway, Harry H; Denaxas, Spiros S; Prieto, David D; Casas, Juan Pablo JP

Publication Date: 2019-12-11

Variant appearance in text: rs17300741

PubMed Link: 31827124

Variant Present in the following documents:

• Main text
• 41598_2019_Article_54849.pdf

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Multiple Membrane Transporters and Some Immune Regulatory Genes are Major Genetic Factors to Gout.

The Open Rheumatology Journal

Zhu, Weifeng W; Deng, Yan Y; Zhou, Xiaodong X

Publication Date: 2018

Variant appearance in text: rs17300741

PubMed Link: 30123371

Variant Present in the following documents:

• Main text
• TORJ-12-94.pdf

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The impact of diuretic use and ABCG2 genotype on the predictive performance of a published allopurinol dosing tool.

British Journal Of Clinical Pharmacology

Wright, Daniel F B DFB; Dalbeth, Nicola N; Phipps-Green, Amanda J AJ; Merriman, Tony R TR; Barclay, Murray L ML; Drake, Jill J; Tan, Paul P; Horne, Anne A; Stamp, Lisa K LK

Publication Date: 2018-05

Variant appearance in text: rs17300741

PubMed Link: 29341237

Variant Present in the following documents:

• Main text

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Identification of CDC42BPG as a novel susceptibility locus for hyperuricemia in a Japanese population.

Molecular Genetics And Genomics : Mgg

Yasukochi, Yoshiki Y; Sakuma, Jun J; Takeuchi, Ichiro I; Kato, Kimihiko K; Oguri, Mitsutoshi M; Fujimaki, Tetsuo T; Horibe, Hideki H; Yamada, Yoshiji Y

Publication Date: 2018-04

Variant appearance in text: rs17300741

PubMed Link: 29124443

Variant Present in the following documents:

• 438_2017_Article_1394.pdf

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Replication of Gout/Urate Concentrations GWAS Susceptibility Loci Associated with Gout in a Han Chinese Population.

Scientific Reports

Li, Zhiqiang Z; Zhou, Zhaowei Z; Hou, Xu X; Lu, Dajiang D; Yuan, Xuan X; Lu, Jie J; Wang, Can C; Han, Lin L; Cui, Lingling L; Liu, Zhen Z; Chen, Jianhua J; Cheng, Xiaoyu X; Zhang, Keke K; Ji, Jue J; Jia, Zhaotong Z; Ma, Lidan L; Xin, Ying Y; Liu, Tian T; Yu, Qing Q; Ren, Wei W; Wang, Xuefeng X; Li, Xinde X; Mi, Qing-Sheng QS; Shi, Yongyong Y; Li, Changgui C

Publication Date: 2017-06-22

Variant appearance in text: rs17300741

PubMed Link: 28642574

Variant Present in the following documents:

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Analysis of ABCG2 and other urate transporters in uric acid homeostasis in chronic kidney disease: potential role of remote sensing and signaling.

Clinical Kidney Journal

Bhatnagar, Vibha V; Richard, Erin L EL; Wu, Wei W; Nievergelt, Caroline M CM; Lipkowitz, Michael S MS; Jeff, Janina J; Maihofer, Adam X AX; Nigam, Sanjay K SK

Publication Date: 2016-06

Variant appearance in text: rs17300741

PubMed Link: 27274832

Variant Present in the following documents:

• Main text
• sfw010.pdf

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SHEsisPlus, a toolset for genetic studies on polyploid species.

Scientific Reports

Shen, Jiawei J; Li, Zhiqiang Z; Chen, Jianhua J; Song, Zhijian Z; Zhou, Zhaowei Z; Shi, Yongyong Y

Publication Date: 2016-04-06

Variant appearance in text: rs17300741

PubMed Link: 27048905

Variant Present in the following documents:

• Main text
• srep24095.pdf

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Mendelian randomization studies of biomarkers and type 2 diabetes.

Endocrine Connections

Abbasi, Ali A

Publication Date: 2015-12

Variant appearance in text: rs17300741

PubMed Link: 26446360

Variant Present in the following documents:

• Main text

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Polymorphisms in GCKR, SLC17A1 and SLC22A12 were associated with phenotype gout in Han Chinese males: a case-control study.

Bmc Medical Genetics

Zhou, Zhao-Wei ZW; Cui, Ling-Ling LL; Han, Lin L; Wang, Can C; Song, Zhi-Jian ZJ; Shen, Jia-Wei JW; Li, Zhi-Qiang ZQ; Chen, Jian-Hua JH; Wen, Zu-Jia ZJ; Wang, Xiao-Min XM; Shi, Yong-Yong YY; Li, Chang-Gui CG

Publication Date: 2015-08-20

Variant appearance in text: rs17300741

PubMed Link: 26290326

Variant Present in the following documents:

• Main text

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Common variants related to serum uric acid concentrations are associated with glucose metabolism and insulin secretion in a Chinese population.

Plos One

Sun, Xue X; Zhang, Rong R; Jiang, Feng F; Tang, Shanshan S; Chen, Miao M; Peng, Danfeng D; Yan, Jing J; Wang, Tao T; Wang, Shiyun S; Bao, Yuqian Y; Hu, Cheng C; Jia, Weiping W

Publication Date: 2015

Variant appearance in text: rs17300741

PubMed Link: 25617895

Variant Present in the following documents:

• Main text
• pone.0116714.pdf

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Gout: a review of nonmodifiable and modifiable risk factors.

Rheumatic Diseases Clinics Of North America

MacFarlane, Lindsey A LA; Kim, Seoyoung C SC

Publication Date: 2014-11

Variant appearance in text: rs17300741

PubMed Link: 25437279

Variant Present in the following documents:

• Main text

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Serum uric acid levels are associated with polymorphisms in the SLC2A9, SF1, and GCKR genes in a Chinese population.

Acta Pharmacologica Sinica

Sun, Xue X; Jiang, Feng F; Zhang, Rong R; Tang, Shan-shan SS; Chen, Miao M; Peng, Dan-feng DF; Yan, Jing J; Wang, Tao T; Wang, Shi-yun SY; Bao, Yu-qian YQ; Hu, Cheng C; Jia, Wei-ping WP

Publication Date: 2014-11

Variant appearance in text: rs17300741

PubMed Link: 25283508

Variant Present in the following documents:

• Main text

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A genome-wide association study identifies common variants influencing serum uric acid concentrations in a Chinese population.

Bmc Medical Genomics

Yang, Binyao B; Mo, Zengnan Z; Wu, Chen C; Yang, Handong H; Yang, Xiaobo X; He, Yunfeng Y; Gui, Lixuan L; Zhou, Li L; Guo, Huan H; Zhang, Xiaomin X; Yuan, Jing J; Dai, Xiayun X; Li, Jun J; Qiu, Gaokun G; Huang, Suli S; Deng, Qifei Q; Feng, Yingying Y; Guan, Lei L; Hu, Die D; Zhang, Xiao X; Wang, Tian T; Zhu, Jiang J; Min, Xinwen X; Lang, Mingjian M; Li, Dongfeng D; Hu, Frank B FB; Lin, Dongxin D; Wu, Tangchun T; He, Meian M

Publication Date: 2014-02-11

Variant appearance in text: rs17300741

PubMed Link: 24513273

Variant Present in the following documents:

• Main text

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Association analysis of the SLC22A11 (organic anion transporter 4) and SLC22A12 (urate transporter 1) urate transporter locus with gout in New Zealand case-control sample sets reveals multiple ancestral-specific effects.

Arthritis Research & Therapy

Flynn, Tanya J TJ; Phipps-Green, Amanda A; Hollis-Moffatt, Jade E JE; Merriman, Marilyn E ME; Topless, Ruth R; Montgomery, Grant G; Chapman, Brett B; Stamp, Lisa K LK; Dalbeth, Nicola N; Merriman, Tony R TR

Publication Date: 2013

Variant appearance in text: rs17300741

PubMed Link: 24360580

Variant Present in the following documents:

• Main text
• ar4417.pdf

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The genetics of hyperuricaemia and gout.

Nature Reviews. Rheumatology

Reginato, Anthony M AM; Mount, David B DB; Yang, Irene I; Choi, Hyon K HK

Publication Date: 2012-10

Variant appearance in text: rs17300741

PubMed Link: 22945592

Variant Present in the following documents:

• Main text

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Instrumental variable estimation of the causal effect of plasma 25-hydroxy-vitamin D on colorectal cancer risk: a mendelian randomization analysis.

Plos One

Theodoratou, Evropi E; Palmer, Tom T; Zgaga, Lina L; Farrington, Susan M SM; McKeigue, Paul P; Din, Farhat V N FV; Tenesa, Albert A; Davey-Smith, George G; Dunlop, Malcolm G MG; Campbell, Harry H

Publication Date: 2012

Variant appearance in text: rs17300741

PubMed Link: 22701574

Variant Present in the following documents:

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Genome-wide association of serum uric acid concentration: replication of sequence variants in an island population of the Adriatic coast of Croatia.

Annals Of Human Genetics

Karns, Rebekah R; Zhang, Ge G; Sun, Guangyun G; Rao Indugula, Subba S; Cheng, Hong H; Havas-Augustin, Dubravka D; Novokmet, Natalija N; Rudan, Dusko D; Durakovic, Zijad Z; Missoni, Sasa S; Chakraborty, Ranajit R; Rudan, Pavao P; Deka, Ranjan R

Publication Date: 2012-03

Variant appearance in text: rs17300741

PubMed Link: 22229870

Variant Present in the following documents:

• Main text

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Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele.

Human Molecular Genetics

Tin, Adrienne A; Woodward, Owen M OM; Kao, Wen Hong Linda WH; Liu, Ching-Ti CT; Lu, Xiaoning X; Nalls, Michael A MA; Shriner, Daniel D; Semmo, Mariam M; Akylbekova, Ermeg L EL; Wyatt, Sharon B SB; Hwang, Shih-Jen SJ; Yang, Qiong Q; Zonderman, Alan B AB; Adeyemo, Adebowale A AA; Palmer, Cameron C; Meng, Yan Y; Reilly, Muredach M; Shlipak, Michael G MG; Siscovick, David D; Evans, Michele K MK; Rotimi, Charles N CN; Flessner, Michael F MF; Köttgen, Michael M; Cupples, L Adrienne LA; Fox, Caroline S CS; Köttgen, Anna A; ,

Publication Date: 2011-10-15

Variant appearance in text: rs17300741

PubMed Link: 21768215

Variant Present in the following documents:

• Main text

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Increased power of mixed models facilitates association mapping of 10 loci for metabolic traits in an isolated population.

Human Molecular Genetics

Kenny, Eimear E EE; Kim, Minseung M; Gusev, Alexander A; Lowe, Jennifer K JK; Salit, Jacqueline J; Smith, J Gustav JG; Kovvali, Sirisha S; Kang, Hyun Min HM; Newton-Cheh, Christopher C; Daly, Mark J MJ; Stoffel, Markus M; Altshuler, David M DM; Friedman, Jeffrey M JM; Eskin, Eleazar E; Breslow, Jan L JL; Pe'er, Itsik I

Publication Date: 2011-02-15

Variant appearance in text: rs17300741

PubMed Link: 21118897

Variant Present in the following documents:

• Main text

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Common polymorphisms influencing serum uric acid levels contribute to susceptibility to gout, but not to coronary artery disease.

Plos One

Stark, Klaus K; Reinhard, Wibke W; Grassl, Martina M; Erdmann, Jeanette J; Schunkert, Heribert H; Illig, Thomas T; Hengstenberg, Christian C

Publication Date: 2009-11-05

Variant appearance in text: rs17300741

PubMed Link: 19890391

Variant Present in the following documents:

• Main text
• pone.0007729.pdf

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Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.

Plos Genetics

Kolz, Melanie M; Johnson, Toby T; Sanna, Serena S; Teumer, Alexander A; Vitart, Veronique V; Perola, Markus M; Mangino, Massimo M; Albrecht, Eva E; Wallace, Chris C; Farrall, Martin M; Johansson, Asa A; Nyholt, Dale R DR; Aulchenko, Yurii Y; Beckmann, Jacques S JS; Bergmann, Sven S; Bochud, Murielle M; Brown, Morris M; Campbell, Harry H; , ; Connell, John J; Dominiczak, Anna A; Homuth, Georg G; Lamina, Claudia C; McCarthy, Mark I MI; , ; Meitinger, Thomas T; Mooser, Vincent V; Munroe, Patricia P; Nauck, Matthias M; Peden, John J; Prokisch, Holger H; Salo, Perttu P; Salomaa, Veikko V; Samani, Nilesh J NJ; Schlessinger, David D; Uda, Manuela M; Völker, Uwe U; Waeber, Gérard G; Waterworth, Dawn D; Wang-Sattler, Rui R; Wright, Alan F AF; Adamski, Jerzy J; Whitfield, John B JB; Gyllensten, Ulf U; Wilson, James F JF; Rudan, Igor I; Pramstaller, Peter P; Watkins, Hugh H; , ; Doering, Angela A; Wichmann, H-Erich HE; , ; Spector, Tim D TD; Peltonen, Leena L; Völzke, Henry H; Nagaraja, Ramaiah R; Vollenweider, Peter P; Caulfield, Mark M; , ; Illig, Thomas T; Gieger, Christian C

Publication Date: 2009-06

Variant appearance in text: rs17300741

PubMed Link: 19503597

Variant Present in the following documents:

• Main text

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