Androgen Receptor Signaling Inhibition in Advanced Castration Resistance Prostate Cancer: What Is Expected for the Near Future?
Cancers
Pozas, Javier J; Álvarez Rodríguez, Sara S; Fernández, Víctor Albarrán VA; Burgos, Javier J; Santoni, Matteo M; Manneh Kopp, Ray R; Molina-Cerrillo, Javier J; Alonso-Gordoa, Teresa T
Overcoming the mechanisms of primary and acquired resistance to new generation hormonal therapies in advanced prostate cancer: focus on androgen receptor independent pathways.
Cancer Drug Resistance (Alhambra, Calif.)
Bungaro, Maristella M; Buttigliero, Consuelo C; Tucci, Marcello M
The natural compound atraric acid suppresses androgen-regulated neo-angiogenesis of castration-resistant prostate cancer through angiopoietin 2.
Oncogene
Ehsani, Marzieh M; Bartsch, Sophie S; Rasa, Seyed Mohammad Mahdi SMM; Dittmann, Jessica J; Pungsrinont, Thanakorn T; Neubert, Laura L; Huettner, Soeren S SS; Kotolloshi, Roland R; Schindler, Katrin K; Ahmad, Aya A; Mosig, Alexander S AS; Adam, Lisa L; Ori, Alessandro A; Neri, Francesco F; Berndt, Alexander A; Grimm, Marc-Oliver MO; Baniahmad, Aria A
Biomarkers of Castrate Resistance in Prostate Cancer: Androgen Receptor Amplification and T877A Mutation Detection by Multiplex Droplet Digital PCR.
Journal Of Clinical Medicine
Young, Francis P FP; Becker, Therese M TM; Nimir, Mohammed M; Opperman, Thomas T; Chua, Wei W; Balakrishnar, Bavanthi B; de Souza, Paul P; Ma, Yafeng Y
Biomarkers of Castrate Resistance in Prostate Cancer: Androgen Receptor Amplification and T877A Mutation Detection by Multiplex Droplet Digital PCR.
Journal Of Clinical Medicine
Young, Francis P FP; Becker, Therese M TM; Nimir, Mohammed M; Opperman, Thomas T; Chua, Wei W; Balakrishnar, Bavanthi B; de Souza, Paul P; Ma, Yafeng Y
Second-Generation Jak2 Inhibitors for Advanced Prostate Cancer: Are We Ready for Clinical Development?
Cancers
Beinhoff, Paul P; Sabharwal, Lavannya L; Udhane, Vindhya V; Maranto, Cristina C; LaViolette, Peter S PS; Jacobsohn, Kenneth M KM; Tsai, Susan S; Iczkowski, Kenneth A KA; Wang, Liang L; Hall, William A WA; Dehm, Scott M SM; Kilari, Deepak D; Nevalainen, Marja T MT
Exploration and Biological Evaluation of Basic Heteromonocyclic Propanamide Derivatives as SARDs for the Treatment of Enzalutamide-Resistant Prostate Cancer.
Journal Of Medicinal Chemistry
He, Yali Y; Hwang, Dong-Jin DJ; Ponnusamy, Suriyan S; Thiyagarajan, Thirumagal T; Mohler, Michael L ML; Narayanan, Ramesh R; Miller, Duane D DD
Design, synthesis and evaluation of novel enzalutamide analogues as potential anticancer agents.
Heliyon
Bhole, Ritesh P RP; Chikhale, Rupesh V RV; Wavhale, Ravindra D RD; Asmary, Fatmah Ali FA; Almutairi, Tahani Mazyad TM; Alhajri, Hassna Mohammed HM; Bonde, Chandrakant G CG
Assessment of STAT5 as a potential therapy target in enzalutamide-resistant prostate cancer.
Plos One
Erb, Holger H H HHH; Bodenbender, Julia J; Handle, Florian F; Diehl, Tamara T; Donix, Lukas L; Tsaur, Igor I; Gleave, Martin M; Haferkamp, Axel A; Huber, Johannes J; Fuessel, Susanne S; Juengel, Eva E; Culig, Zoran Z; Thomas, Christian C
Quantitative Evaluation of the Transcriptional Activity of Steroid Hormone Receptor Mutants and Variants Using a Single Vector With Two Reporters and a Receptor Expression Cassette.
Frontiers In Endocrinology
Ji, Huimin H; Li, Ying Y; Liu, Zhao Z; Tang, Min M; Zou, Lihui L; Su, Fei F; Zhang, Yaqun Y; Zhang, Junhua J; Li, Hexin H; Li, Lin L; Ai, Bin B; Ma, Jie J; Wang, Lunan L; Liu, Ming M; Xiao, Fei F
Enzalutamide-Induced Feed-Forward Signaling Loop Promotes Therapy-Resistant Prostate Cancer Growth Providing an Exploitable Molecular Target for Jak2 Inhibitors.
Molecular Cancer Therapeutics
Udhane, Vindhya V; Maranto, Cristina C; Hoang, David T DT; Gu, Lei L; Erickson, Andrew A; Devi, Savita S; Talati, Pooja G PG; Banerjee, Anjishnu A; Iczkowski, Kenneth A KA; Jacobsohn, Kenneth K; See, William A WA; Mirtti, Tuomas T; Kilari, Deepak D; Nevalainen, Marja T MT
A population pharmacokinetic analysis of the oral CYP17 lyase and androgen receptor inhibitor seviteronel in patients with advanced/metastatic castration-resistant prostate cancer or breast cancer.
Cancer Chemotherapy And Pharmacology
Peer, Cody J CJ; Schmidt, Keith T KT; Kindrick, Jessica D JD; Eisner, Joel R JR; Brown, Victoria V VV; Baskin-Bey, Edwina E; Madan, Ravi R; Figg, William D WD
Rational design and synthesis of novel phenylsulfonyl-benzamides as anti-prostate cancer agents.
Medchemcomm
Bassetto, Marcella M; Ferla, Salvatore S; Giancotti, Gilda G; Pertusati, Fabrizio F; Westwell, Andrew D AD; Brancale, Andrea A; McGuigan, Christopher C