Publications:

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Drug resistance in metastatic castration-resistant prostate cancer: an update on the status quo.

Cancer Drug Resistance (Alhambra, Calif.)

Yehya, Amani A; Ghamlouche, Fatima F; Zahwe, Amin A; Zeid, Yousef Y; Wakimian, Kevork K; Mukherji, Deborah D; Abou-Kheir, Wassim W

Publication Date: 2022

Variant appearance in text: PC: H875Y

PubMed Link: 36176747

Variant Present in the following documents:

• cdr-5-3-667.pdf

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Second generation androgen receptor antagonists and challenges in prostate cancer treatment.

Cell Death & Disease

Chen, Yanhua Y; Zhou, Qianqian Q; Hankey, William W; Fang, Xiaosheng X; Yuan, Fuwen F

Publication Date: 2022-07-21

Variant appearance in text: PC: H875Y

PubMed Link: 35864113

Variant Present in the following documents:

• 41419_2022_Article_5084.pdf

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Identifying Phased Mutations and Complex Rearrangements in Human Prostate Cancer Cell Lines through Linked-Read Whole-Genome Sequencing.

Molecular Cancer Research : Mcr

Pham, Minh-Tam MT; Gupta, Anuj A; Gupta, Harshath H; Vaghasia, Ajay A; Skaist, Alyza A; Garrison, McKinzie A MA; Coulter, Jonathan B JB; Haffner, Michael C MC; Zheng, S Lilly SL; Xu, Jianfeng J; DeStefano Shields, Christina C; Isaacs, William B WB; Wheelan, Sarah J SJ; Nelson, William G WG; Yegnasubramanian, Srinivasan S

Publication Date: 2022-07-06

Variant appearance in text: PC: H875Y

PubMed Link: 35452513

Variant Present in the following documents:

• mcr-21-0683_supplementary_methods_and_figures_s1-5_suppsf1-5.pdf

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Clinical Applications of Liquid Biopsy in Prostate Cancer: From Screening to Predictive Biomarker.

Cancers

Ionescu, Filip F; Zhang, Jingsong J; Wang, Liang L

Publication Date: 2022-03-29

Variant appearance in text: PC: H875Y

PubMed Link: 35406500

Variant Present in the following documents:

• Main text
• cancers-14-01728.pdf

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Comparative Effectiveness of Abiraterone and Enzalutamide in Patients With Metastatic Castration-Resistant Prostate Cancer in Taiwan.

Frontiers In Oncology

Li, Pei-Yu PY; Lu, Ying-Hao YH; Chen, Chung-Yu CY

Publication Date: 2022

Variant appearance in text: PC: H875Y

PubMed Link: 35330713

Variant Present in the following documents:

• fonc-12-822375.pdf

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Overcoming prostate cancer drug resistance with a novel organosilicon small molecule.

Neoplasia (New York, N.Y.)

Zhao, Rui R; Ma, Xiaowei X; Bai, Lijuan L; Li, Xin X; Mamouni, Kenza K; Yang, Yang Y; Liu, HongYan H; Danaher, Alira A; Cook, Nicholas N; Kucuk, Omer O; Hodges, Robert S RS; Gera, Lajos L; Wu, Daqing D

Publication Date: 2021-12

Variant appearance in text: PC: H875Y

PubMed Link: 34781084

Variant Present in the following documents:

• main.pdf

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Overcoming enzalutamide resistance in metastatic prostate cancer by targeting sphingosine kinase.

Ebiomedicine

Lin, Hui-Ming HM; Mak, Blossom B; Yeung, Nicole N; Huynh, Kevin K; Meikle, Thomas G TG; Mellett, Natalie A NA; Kwan, Edmond M EM; Fettke, Heidi H; Tran, Ben B; Davis, Ian D ID; Mahon, Kate L KL; Zhang, Alison A; Stockler, Martin R MR; Briscoe, Karen K; Marx, Gavin G; Crumbaker, Megan M; Stricker, Phillip D PD; Du, Pan P; Yu, Jianjun J; Jia, Shidong S; Scheinberg, Tahlia T; Fitzpatrick, Michael M; Bonnitcha, Paul P; Sullivan, David R DR; Joshua, Anthony M AM; Azad, Arun A AA; Butler, Lisa M LM; Meikle, Peter J PJ; Horvath, Lisa G LG

Publication Date: 2021-10

Variant appearance in text: PC: 2623C>T; His875Tyr

PubMed Link: 34656931

Variant Present in the following documents:

• mmc1.pdf

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The inhibitory effect of melatonin on human prostate cancer.

Cell Communication And Signaling : Ccs

Shen, Dexin D; Ju, Lingao L; Zhou, Fenfang F; Yu, Mengxue M; Ma, Haoli H; Zhang, Yi Y; Liu, Tongzu T; Xiao, Yu Y; Wang, Xinghuan X; Qian, Kaiyu K

Publication Date: 2021-03-15

Variant appearance in text: PC: H875Y

PubMed Link: 33722247

Variant Present in the following documents:

• 12964_2021_Article_723.pdf

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Preclinical Models in Prostate Cancer: Resistance to AR Targeting Therapies in Prostate Cancer.

Cancers

Devlies, Wout W; Handle, Florian F; Devos, Gaëtan G; Joniau, Steven S; Claessens, Frank F

Publication Date: 2021-02-22

Variant appearance in text: PC: H875Y

PubMed Link: 33671614

Variant Present in the following documents:

• Main text
• cancers-13-00915.pdf

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New Prognostic Biomarkers in Metastatic Castration-Resistant Prostate Cancer.

Cells

Conteduca, Vincenza V; Mosca, Alessandra A; Brighi, Nicole N; de Giorgi, Ugo U; Rescigno, Pasquale P

Publication Date: 2021-01-19

Variant appearance in text: PC: H875Y

PubMed Link: 33478015

Variant Present in the following documents:

• Main text
• cells-10-00193.pdf

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Darolutamide: A Review in Non-Metastatic Castration-Resistant Prostate Cancer.

Targeted Oncology

Scott, Lesley J LJ

Publication Date: 2020-12

Variant appearance in text: PC: H875Y

PubMed Link: 33237495

Variant Present in the following documents:

• Main text
• 11523_2020_Article_779.pdf

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Recent Discoveries in the Androgen Receptor Pathway in Castration-Resistant Prostate Cancer.

Frontiers In Oncology

Obinata, Daisuke D; Lawrence, Mitchell G MG; Takayama, Kenichi K; Choo, Nicholas N; Risbridger, Gail P GP; Takahashi, Satoru S; Inoue, Satoshi S

Publication Date: 2020

Variant appearance in text: PC: H875Y

PubMed Link: 33134178

Variant Present in the following documents:

• fonc-10-581515.pdf

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Evaluation of Commercial Circulating Tumor DNA Test in Metastatic Prostate Cancer.

Jco Precision Oncology

Taavitsainen, Sinja S; Annala, Matti M; Ledet, Elisa E; Beja, Kevin K; Miller, Patrick J PJ; Moses, Marcus M; Nykter, Matti M; Chi, Kim N KN; Sartor, Oliver O; Wyatt, Alexander W AW

Publication Date: 2019

Variant appearance in text: PC: H875Y

PubMed Link: 32914020

Variant Present in the following documents:

• PO.19.00014.pdf

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Plasma Androgen Receptor in Prostate Cancer.

Cancers

Conteduca, Vincenza V; Gurioli, Giorgia G; Brighi, Nicole N; Lolli, Cristian C; Schepisi, Giuseppe G; Casadei, Chiara C; Burgio, Salvatore Luca SL; Gargiulo, Stefania S; Ravaglia, Giorgia G; Rossi, Lorena L; Altavilla, Amelia A; Farolfi, Alberto A; Menna, Cecilia C; Colangione, Sarah Pia SP; Pulvirenti, Mario M; Romeo, Antonino A; De Giorgi, Ugo U

Publication Date: 2019-11-04

Variant appearance in text: PC: H875Y

PubMed Link: 31689899

Variant Present in the following documents:

• cancers-11-01719.pdf

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Cellular and Molecular Mechanisms Underlying Prostate Cancer Development: Therapeutic Implications.

Medicines (Basel, Switzerland)

Testa, Ugo U; Castelli, Germana G; Pelosi, Elvira E

Publication Date: 2019-07-30

Variant appearance in text: PC: H875Y

PubMed Link: 31366128

Variant Present in the following documents:

• Main text
• medicines-06-00082.pdf

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Understanding the impacts of missense mutations on structures and functions of human cancer-related genes: A preliminary computational analysis of the COSMIC Cancer Gene Census.

Plos One

Malhotra, Sony S; Alsulami, Ali F AF; Heiyun, Yang Y; Ochoa, Bernardo Montano BM; Jubb, Harry H; Forbes, Simon S; Blundell, Tom L TL

Publication Date: 2019

Variant appearance in text: PC: H875Y

PubMed Link: 31323058

Variant Present in the following documents:

• pone.0219935.pdf

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Metastatic prostate cancer remains incurable, why?

Asian Journal Of Urology

Dong, Liang L; Zieren, Richard C RC; Xue, Wei W; de Reijke, Theo M TM; Pienta, Kenneth J KJ

Publication Date: 2019-01

Variant appearance in text: PC: H875Y

PubMed Link: 30775246

Variant Present in the following documents:

• main.pdf

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Circulating tumor DNA in advanced prostate cancer: transitioning from discovery to a clinically implemented test.

Prostate Cancer And Prostatic Diseases

González-Billalabeitia, Enrique E; Conteduca, Vincenza V; Wetterskog, Daniel D; Jayaram, Anuradha A; Attard, Gerhardt G

Publication Date: 2019-05

Variant appearance in text: PC: 2623C>T

PubMed Link: 30413805

Variant Present in the following documents:

• emss-79467.pdf

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Androgen receptor splice variant-7 expression emerges with castration resistance in prostate cancer.

The Journal Of Clinical Investigation

Sharp, Adam A; Coleman, Ilsa I; Yuan, Wei W; Sprenger, Cynthia C; Dolling, David D; Rodrigues, Daniel Nava DN; Russo, Joshua W JW; Figueiredo, Ines I; Bertan, Claudia C; Seed, George G; Riisnaes, Ruth R; Uo, Takuma T; Neeb, Antje A; Welti, Jonathan J; Morrissey, Colm C; Carreira, Suzanne S; Luo, Jun J; Nelson, Peter S PS; Balk, Steven P SP; True, Lawrence D LD; de Bono, Johann S JS; Plymate, Stephen R SR

Publication Date: 2019-01-02

Variant appearance in text: PC: H875Y

PubMed Link: 30334814

Variant Present in the following documents:

• Main text

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Castration-Resistant Prostate Cancer Refractory to Second-Generation Androgen Receptor Axis-Targeted Agents: Opportunities and Challenges.

Cancers

Kita, Yuki Y; Goto, Takayuki T; Akamatsu, Shusuke S; Yamasaki, Toshinari T; Inoue, Takahiro T; Ogawa, Osamu O; Kobayashi, Takashi T

Publication Date: 2018-09-21

Variant appearance in text: PC: H875Y

PubMed Link: 30248934

Variant Present in the following documents:

• Main text
• cancers-10-00345.pdf

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Constitutively active androgen receptor splice variants AR-V3, AR-V7 and AR-V9 are co-expressed in castration-resistant prostate cancer metastases.

British Journal Of Cancer

Kallio, Heini M L HML; Hieta, Reija R; Latonen, Leena L; Brofeldt, Anniina A; Annala, Matti M; Kivinummi, Kati K; Tammela, Teuvo L TL; Nykter, Matti M; Isaacs, William B WB; Lilja, Hans G HG; Bova, G Steven GS; Visakorpi, Tapio T

Publication Date: 2018-08

Variant appearance in text: PC: H875Y

PubMed Link: 29988112

Variant Present in the following documents:

• Main text
• 41416_2018_Article_172.pdf

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Novel galeterone analogs act independently of AR and AR-V7 for the activation of the unfolded protein response and induction of apoptosis in the CWR22Rv1 prostate cancer cell model.

Oncotarget

McCarty, David J DJ; Huang, Weiliang W; Kane, Maureen A MA; Purushottamachar, Puranik P; Gediya, Lalji K LK; Njar, Vincent C O VCO

Publication Date: 2017-10-24

Variant appearance in text: PC: H875Y

PubMed Link: 29179452

Variant Present in the following documents:

• Main text
• oncotarget-08-88501.pdf

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Clinical relevance of androgen receptor alterations in prostate cancer.

Endocrine Connections

Jernberg, Emma E; Bergh, Anders A; Wikström, Pernilla P

Publication Date: 2017-11

Variant appearance in text: PC: H875Y

PubMed Link: 29030409

Variant Present in the following documents:

• Main text

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Clinical application of a cancer genomic profiling assay to guide precision medicine decisions.

Personalized Medicine

Eifert, Cheryl C; Pantazi, Angeliki A; Sun, Ruobai R; Xu, Jia J; Cingolani, Pablo P; Heyer, Joerg J; Russell, Meaghan M; Lvova, Maria M; Ring, Jennifer J; Tse, Julie Y JY; Lyle, Stephen S; Protopopov, Alexei A

Publication Date: 2017-07

Variant appearance in text: PC: H875Y

PubMed Link: 28890729

Variant Present in the following documents:

• pme-14-309.pdf

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Circulating tumor cells in prostate cancer: Precision diagnosis and therapy.

Oncology Letters

Liu, Weiwei W; Yin, Binbin B; Wang, Xuchu X; Yu, Pan P; Duan, Xiuzhi X; Liu, Chunhua C; Wang, Ben B; Tao, Zhihua Z

Publication Date: 2017-08

Variant appearance in text: PC: H875Y

PubMed Link: 28789337

Variant Present in the following documents:

• ol-14-02-1223.pdf

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Detection fidelity of AR mutations in plasma derived cell-free DNA.

Oncotarget

Goldstein, Alexa A; Toro, Patricia Valda PV; Lee, Justin J; Silberstein, John L JL; Nakazawa, Mary M; Waters, Ian I; Cravero, Karen K; Chu, David D; Cochran, Rory L RL; Kim, Minsoo M; Shinn, Daniel D; Torquato, Samantha S; Hughes, Robert M RM; Pallavajjala, Aparna A; Carducci, Michael A MA; Paller, Channing J CJ; Denmeade, Samuel R SR; Kressel, Bruce B; Trock, Bruce J BJ; Eisenberger, Mario A MA; Antonarakis, Emmanuel S ES; Park, Ben H BH; Hurley, Paula J PJ

Publication Date: 2017-02-28

Variant appearance in text: PC: H875Y

PubMed Link: 28152506

Variant Present in the following documents:

• oncotarget-08-15651.pdf

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Molecular mechanisms underlying resistance to androgen deprivation therapy in prostate cancer.

Oncotarget

Wadosky, Kristine M KM; Koochekpour, Shahriar S

Publication Date: 2016-09-27

Variant appearance in text: PC: H875Y

PubMed Link: 27487144

Variant Present in the following documents:

• oncotarget-07-64447.pdf

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The mutational landscape of lethal castration-resistant prostate cancer.

Nature

Grasso, Catherine S CS; Wu, Yi-Mi YM; Robinson, Dan R DR; Cao, Xuhong X; Dhanasekaran, Saravana M SM; Khan, Amjad P AP; Quist, Michael J MJ; Jing, Xiaojun X; Lonigro, Robert J RJ; Brenner, J Chad JC; Asangani, Irfan A IA; Ateeq, Bushra B; Chun, Sang Y SY; Siddiqui, Javed J; Sam, Lee L; Anstett, Matt M; Mehra, Rohit R; Prensner, John R JR; Palanisamy, Nallasivam N; Ryslik, Gregory A GA; Vandin, Fabio F; Raphael, Benjamin J BJ; Kunju, Lakshmi P LP; Rhodes, Daniel R DR; Pienta, Kenneth J KJ; Chinnaiyan, Arul M AM; Tomlins, Scott A SA

Publication Date: 2012-07-12

Variant appearance in text: PC: H875Y

PubMed Link: 22722839

Variant Present in the following documents:

• NIHMS368879-supplement-2.xlsx, sheet 4
• NIHMS368879-supplement-1.pdf

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