JAK-STAT signaling in inflammatory breast cancer enables chemotherapy-resistant cell states.
Cancer Research
Stevens, Laura E LE; Peluffo, Guillermo G; Qiu, Xintao X; Temko, Daniel D; Fassl, Anne A; Li, Zheqi Z; Trinh, Anne A; Seehawer, Marco M; Jovanovic, Bojana B; Aleckovic, Masa M; Wilde, Callahan M CM; Geck, Renee C RC; Shu, Shaokun S; Kingston, Natalie L NL; Harper, Nicholas W NW; Almendro, Vanessa V; Pyke, Alanna L AL; Egri, Shawn B SB; Papanastasiou, Malvina M; Clement, Kendell K; Zhou, Ningxuan N; Walker, Sarah S; Salas, Jacqueline J; Park, So Yeon SY; Frank, David A DA; Meissner, Alexander A; Jaffe, Jacob D JD; Sicinski, Piotr P; Toker, Alex A; Michor, Franziska F; Long, Henry W HW; Overmoyer, Beth A BA; Polyak, Kornelia K
Publication Date: 2022-11-21
Variant appearance in text: CORO1B: 1008-112C>T; rs2302264
Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis.
Elife
Nandakumar, Satish K SK; McFarland, Sean K SK; Mateyka, Laura M LM; Lareau, Caleb A CA; Ulirsch, Jacob C JC; Ludwig, Leif S LS; Agarwal, Gaurav G; Engreitz, Jesse M JM; Przychodzen, Bartlomiej B; McConkey, Marie M; Cowley, Glenn S GS; Doench, John G JG; Maciejewski, Jaroslaw P JP; Ebert, Benjamin L BL; Root, David E DE; Sankaran, Vijay G VG
Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis.
Nature Communications
Benyamin, Beben B; Esko, Tonu T; Ried, Janina S JS; Radhakrishnan, Aparna A; Vermeulen, Sita H SH; Traglia, Michela M; Gögele, Martin M; Anderson, Denise D; Broer, Linda L; Podmore, Clara C; Luan, Jian'an J; Kutalik, Zoltan Z; Sanna, Serena S; van der Meer, Peter P; Tanaka, Toshiko T; Wang, Fudi F; Westra, Harm-Jan HJ; Franke, Lude L; Mihailov, Evelin E; Milani, Lili L; Hälldin, Jonas J; Häldin, Jonas J; Winkelmann, Juliane J; Meitinger, Thomas T; Thiery, Joachim J; Peters, Annette A; Waldenberger, Melanie M; Rendon, Augusto A; Jolley, Jennifer J; Sambrook, Jennifer J; Kiemeney, Lambertus A LA; Sweep, Fred C FC; Sala, Cinzia F CF; Schwienbacher, Christine C; Pichler, Irene I; Hui, Jennie J; Demirkan, Ayse A; Isaacs, Aaron A; Amin, Najaf N; Steri, Maristella M; Waeber, Gérard G; Verweij, Niek N; Powell, Joseph E JE; Nyholt, Dale R DR; Heath, Andrew C AC; Madden, Pamela A F PA; Visscher, Peter M PM; Wright, Margaret J MJ; Montgomery, Grant W GW; Martin, Nicholas G NG; Hernandez, Dena D; Bandinelli, Stefania S; van der Harst, Pim P; Uda, Manuela M; Vollenweider, Peter P; Scott, Robert A RA; Langenberg, Claudia C; Wareham, Nicholas J NJ; , ; van Duijn, Cornelia C; Beilby, John J; Pramstaller, Peter P PP; Hicks, Andrew A AA; Ouwehand, Willem H WH; Oexle, Konrad K; Gieger, Christian C; Metspalu, Andres A; Camaschella, Clara C; Toniolo, Daniela D; Swinkels, Dorine W DW; Whitfield, John B JB
Rare and low-frequency coding variants in CXCR2 and other genes are associated with hematological traits.
Nature Genetics
Auer, Paul L PL; Teumer, Alexander A; Schick, Ursula U; O'Shaughnessy, Andrew A; Lo, Ken Sin KS; Chami, Nathalie N; Carlson, Chris C; de Denus, Simon S; Dubé, Marie-Pierre MP; Haessler, Jeff J; Jackson, Rebecca D RD; Kooperberg, Charles C; Perreault, Louis-Philippe Lemieux LP; Nauck, Matthias M; Peters, Ulrike U; Rioux, John D JD; Schmidt, Frank F; Turcot, Valérie V; Völker, Uwe U; Völzke, Henry H; Greinacher, Andreas A; Hsu, Li L; Tardif, Jean-Claude JC; Diaz, George A GA; Reiner, Alexander P AP; Lettre, Guillaume G
Seventy-five genetic loci influencing the human red blood cell.
Nature
van der Harst, Pim P; Zhang, Weihua W; Mateo Leach, Irene I; Rendon, Augusto A; Verweij, Niek N; Sehmi, Joban J; Paul, Dirk S DS; Elling, Ulrich U; Allayee, Hooman H; Li, Xinzhong X; Radhakrishnan, Aparna A; Tan, Sian-Tsung ST; Voss, Katrin K; Weichenberger, Christian X CX; Albers, Cornelis A CA; Al-Hussani, Abtehale A; Asselbergs, Folkert W FW; Ciullo, Marina M; Danjou, Fabrice F; Dina, Christian C; Esko, Tõnu T; Evans, David M DM; Franke, Lude L; Gögele, Martin M; Hartiala, Jaana J; Hersch, Micha M; Holm, Hilma H; Hottenga, Jouke-Jan JJ; Kanoni, Stavroula S; Kleber, Marcus E ME; Lagou, Vasiliki V; Langenberg, Claudia C; Lopez, Lorna M LM; Lyytikäinen, Leo-Pekka LP; Melander, Olle O; Murgia, Federico F; Nolte, Ilja M IM; O'Reilly, Paul F PF; Padmanabhan, Sandosh S; Parsa, Afshin A; Pirastu, Nicola N; Porcu, Eleonora E; Portas, Laura L; Prokopenko, Inga I; Ried, Janina S JS; Shin, So-Youn SY; Tang, Clara S CS; Teumer, Alexander A; Traglia, Michela M; Ulivi, Sheila S; Westra, Harm-Jan HJ; Yang, Jian J; Zhao, Jing Hua JH; Anni, Franco F; Abdellaoui, Abdel A; Attwood, Antony A; Balkau, Beverley B; Bandinelli, Stefania S; Bastardot, François F; Benyamin, Beben B; Boehm, Bernhard O BO; Cookson, William O WO; Das, Debashish D; de Bakker, Paul I W PI; de Boer, Rudolf A RA; de Geus, Eco J C EJ; de Moor, Marleen H MH; Dimitriou, Maria M; Domingues, Francisco S FS; Döring, Angela A; Engström, Gunnar G; Eyjolfsson, Gudmundur Ingi GI; Ferrucci, Luigi L; Fischer, Krista K; Galanello, Renzo R; Garner, Stephen F SF; Genser, Bernd B; Gibson, Quince D QD; Girotto, Giorgia G; Gudbjartsson, Daniel Fannar DF; Harris, Sarah E SE; Hartikainen, Anna-Liisa AL; Hastie, Claire E CE; Hedblad, Bo B; Illig, Thomas T; Jolley, Jennifer J; Kähönen, Mika M; Kema, Ido P IP; Kemp, John P JP; Liang, Liming L; Lloyd-Jones, Heather H; Loos, Ruth J F RJ; Meacham, Stuart S; Medland, Sarah E SE; Meisinger, Christa C; Memari, Yasin Y; Mihailov, Evelin E; Miller, Kathy K; Moffatt, Miriam F MF; Nauck, Matthias M; Novatchkova, Maria M; Nutile, Teresa T; Olafsson, Isleifur I; Onundarson, Pall T PT; Parracciani, Debora D; Penninx, Brenda W BW; Perseu, Lucia L; Piga, Antonio A; Pistis, Giorgio G; Pouta, Anneli A; Puc, Ursula U; Raitakari, Olli O; Ring, Susan M SM; Robino, Antonietta A; Ruggiero, Daniela D; Ruokonen, Aimo A; Saint-Pierre, Aude A; Sala, Cinzia C; Salumets, Andres A; Sambrook, Jennifer J; Schepers, Hein H; Schmidt, Carsten Oliver CO; Silljé, Herman H W HH; Sladek, Rob R; Smit, Johannes H JH; Starr, John M JM; Stephens, Jonathan J; Sulem, Patrick P; Tanaka, Toshiko T; Thorsteinsdottir, Unnur U; Tragante, Vinicius V; van Gilst, Wiek H WH; van Pelt, L Joost LJ; van Veldhuisen, Dirk J DJ; Völker, Uwe U; Whitfield, John B JB; Willemsen, Gonneke G; Winkelmann, Bernhard R BR; Wirnsberger, Gerald G; Algra, Ale A; Cucca, Francesco F; d'Adamo, Adamo Pio AP; Danesh, John J; Deary, Ian J IJ; Dominiczak, Anna F AF; Elliott, Paul P; Fortina, Paolo P; Froguel, Philippe P; Gasparini, Paolo P; Greinacher, Andreas A; Hazen, Stanley L SL; Jarvelin, Marjo-Riitta MR; Khaw, Kay Tee KT; Lehtimäki, Terho T; Maerz, Winfried W; Martin, Nicholas G NG; Metspalu, Andres A; Mitchell, Braxton D BD; Montgomery, Grant W GW; Moore, Carmel C; Navis, Gerjan G; Pirastu, Mario M; Pramstaller, Peter P PP; Ramirez-Solis, Ramiro R; Schadt, Eric E; Scott, James J; Shuldiner, Alan R AR; Smith, George Davey GD; Smith, J Gustav JG; Snieder, Harold H; Sorice, Rossella R; Spector, Tim D TD; Stefansson, Kari K; Stumvoll, Michael M; Tang, W H Wilson WH; Toniolo, Daniela D; Tönjes, Anke A; Visscher, Peter M PM; Vollenweider, Peter P; Wareham, Nicholas J NJ; Wolffenbuttel, Bruce H R BH; Boomsma, Dorret I DI; Beckmann, Jacques S JS; Dedoussis, George V GV; Deloukas, Panos P; Ferreira, Manuel A MA; Sanna, Serena S; Uda, Manuela M; Hicks, Andrew A AA; Penninger, Josef Martin JM; Gieger, Christian C; Kooner, Jaspal S JS; Ouwehand, Willem H WH; Soranzo, Nicole N; Chambers, John C JC
A regulatory polymorphism at position -309 in PTPRCAP is associated with susceptibility to diffuse-type gastric cancer and gene expression.
Neoplasia (New York, N.Y.)
Ju, Hyoungseok H; Lim, Byungho B; Kim, Minjin M; Kim, Yong Sung YS; Kim, Woo Ho WH; Ihm, Chunhwa C; Noh, Seung-Moo SM; Han, Dong Soo DS; Yu, Hang-Jong HJ; Choi, Bo Youl BY; Kang, Changwon C