Publications:

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Organic Anion Transporting Polypeptide 2B1 (OATP2B1) Genetic Variants: In Vitro Functional Characterization and Association With Circulating Concentrations of Endogenous Substrates.

Frontiers In Pharmacology

Medwid, Samantha S; Price, Hayley R HR; Taylor, Daniel P DP; Mailloux, Jaymie J; Schwarz, Ute I UI; Kim, Richard B RB; Tirona, Rommel G RG

Publication Date: 2021

Variant appearance in text: SLCO2B1: 601G>A; rs35199625

PubMed Link: 34594217

Variant Present in the following documents:

• Main text

View BVdb publication page

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Pharmacogenomics of celiprolol - evidence for a role of P-glycoprotein and organic anion transporting polypeptide 1A2 in celiprolol pharmacokinetics.

Clinical And Translational Science

Hirvensalo, Päivi P; Tornio, Aleksi A; Tapaninen, Tuija T; Paile-Hyvärinen, Maria M; Neuvonen, Mikko M; Backman, Janne T JT; Niemi, Mikko M

Publication Date: 2022-02

Variant appearance in text: SLCO2B1: 601G>A; rs35199625

PubMed Link: 34585840

Variant Present in the following documents:

• Main text
• CTS-15-409.pdf

View BVdb publication page

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Pharmacogenomic landscape of COVID-19 therapies from Indian population genomes.

Pharmacogenomics

Sahana, S S; Sivadas, Ambily A; Mangla, Mohit M; Jain, Abhinav A; Bhoyar, Rahul C RC; Pandhare, Kavita K; Mishra, Anushree A; Sharma, Disha D; Imran, Mohamed M; Senthivel, Vigneshwar V; Divakar, Mohit Kumar MK; Rophina, Mercy M; Jolly, Bani B; Batra, Arushi A; Sharma, Sumit S; Siwach, Sanjay S; Jadhao, Arun G AG; Palande, Nikhil V NV; Jha, Ganga Nath GN; Ashrafi, Nishat N; Mishra, Prashant Kumar PK; Vidhya, A K AK; Jain, Suman S; Dash, Debasis D; Kumar, Nachimuthu Senthil NS; Vanlallawma, Andrew A; Sarma, Ranjan Jyoti RJ; Chhakchhuak, Lalchhandama L; Kalyanaraman, Shantaraman S; Mahadevan, Radha R; Kandasamy, Sunitha S; Devi, Pabitha P; Rajagopal, Raskin Erusan RE; Ramya, J Ezhil JE; Devi, P Nirmala PN; Bajaj, Anjali A; Gupta, Vishu V; Mathew, Samatha S; Goswami, Sangam S; Prakash, Savinitha S; Joshi, Kandarp K; Kumla, Meya M; Sreedevi, S S; Gajjar, Devarshi D; Soraisham, Ronibala R; Yadav, Rohit R; Devi, Yumnam Silla YS; Gupta, Aayush A; Mukerji, Mitali M; Ramalingam, Sivaprakash S; Binukumar, B K BK; Sivasubbu, Sridhar S; Scaria, Vinod V

Publication Date: 2021-07

Variant appearance in text: rs35199625

PubMed Link: 34142560

Variant Present in the following documents:

• pgs-2021-0028.pdf

View BVdb publication page

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Disseminated Talaromyces marneffei Infection in a Non-HIV Infant With a Homozygous Private Variant of RELB.

Frontiers In Cellular And Infection Microbiology

Ding, Xiaofang X; Huang, Han H; Zhong, Lili L; Chen, Min M; Peng, Fang F; Zhang, Bing B; Cui, Xinyu X; Yang, Xiu-An XA

Publication Date: 2021

Variant appearance in text: SLCO2B1: V201M; rs35199625

PubMed Link: 33791233

Variant Present in the following documents:

• Table_2.xlsx, sheet 1

View BVdb publication page

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Decoding variants in drug-metabolizing enzymes and transporters in solid tumor patients by whole-exome sequencing.

Saudi Journal Of Biological Sciences

Aboul-Soud, Mourad A M MAM; Alzahrani, Alhussain J AJ; Mahmoud, Amer A

Publication Date: 2021-01

Variant appearance in text: rs35199625

PubMed Link: 33424349

Variant Present in the following documents:

• mmc1.xlsx, sheet 1

View BVdb publication page

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Influence of genetic factors on long-term treatment related neurocognitive complications, and on anxiety and depression in survivors of childhood acute lymphoblastic leukemia: The Petale study.

Plos One

Petrykey, Kateryna K; Lippé, Sarah S; Robaey, Philippe P; Sultan, Serge S; Laniel, Julie J; Drouin, Simon S; Bertout, Laurence L; Beaulieu, Patrick P; St-Onge, Pascal P; Boulet-Craig, Aubrée A; Rezgui, Aziz A; Yasui, Yutaka Y; Sapkota, Yadav Y; Krull, Kevin R KR; Hudson, Melissa M MM; Laverdière, Caroline C; Sinnett, Daniel D; Krajinovic, Maja M

Publication Date: 2019

Variant appearance in text: rs35199625

PubMed Link: 31181069

Variant Present in the following documents:

• Main text

View BVdb publication page

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Pharmacogenetic Factors Affecting Asthma Treatment Response. Potential Implications for Drug Therapy.

Frontiers In Pharmacology

García-Menaya, Jesús Miguel JM; Cordobés-Durán, Concepción C; García-Martín, Elena E; Agúndez, José A G JAG

Publication Date: 2019

Variant appearance in text: rs35199625

PubMed Link: 31178722

Variant Present in the following documents:

• Main text

View BVdb publication page

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Targeted next generation sequencing as a tool for precision medicine.

Bmc Medical Genomics

Gulilat, Markus M; Lamb, Tyler T; Teft, Wendy A WA; Wang, Jian J; Dron, Jacqueline S JS; Robinson, John F JF; Tirona, Rommel G RG; Hegele, Robert A RA; Kim, Richard B RB; Schwarz, Ute I UI

Publication Date: 2019-06-03

Variant appearance in text: rs35199625

PubMed Link: 31159795

Variant Present in the following documents:

• 12920_2019_527_MOESM1_ESM.xlsx, sheet 6

View BVdb publication page

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Enantiospecific Pharmacogenomics of Fluvastatin.

Clinical Pharmacology And Therapeutics

Hirvensalo, Päivi P; Tornio, Aleksi A; Neuvonen, Mikko M; Kiander, Wilma W; Kidron, Heidi H; Paile-Hyvärinen, Maria M; Tapaninen, Tuija T; Backman, Janne T JT; Niemi, Mikko M

Publication Date: 2019-09

Variant appearance in text: SLCO2B1: 601G>A; Val201Met; rs35199625

PubMed Link: 30989645

Variant Present in the following documents:

• Main text
• CPT-106-668-s002.pdf
• CPT-106-668.pdf
• CPT-106-668-s003.pdf

View BVdb publication page

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Organoids as a new model for improving regenerative medicine and cancer personalized therapy in renal diseases.

Cell Death & Disease

Grassi, Ludovica L; Alfonsi, Romina R; Francescangeli, Federica F; Signore, Michele M; De Angelis, Maria Laura ML; Addario, Antonio A; Costantini, Manuela M; Flex, Elisabetta E; Ciolfi, Andrea A; Pizzi, Simone S; Bruselles, Alessandro A; Pallocca, Matteo M; Simone, Giuseppe G; Haoui, Mustapha M; Falchi, Mario M; Milella, Michele M; Sentinelli, Steno S; Di Matteo, Paola P; Stellacci, Emilia E; Gallucci, Michele M; Muto, Giovanni G; Tartaglia, Marco M; De Maria, Ruggero R; Bonci, Désirée D

Publication Date: 2019-02-27

Variant appearance in text: rs35199625

PubMed Link: 30814510

Variant Present in the following documents:

• 41419_2019_1453_MOESM27_ESM.xlsx, sheet 2

View BVdb publication page

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Organic Anion Transporting Polypeptides: Emerging Roles in Cancer Pharmacology.

Molecular Pharmacology

Schulte, Rachael R RR; Ho, Richard H RH

Publication Date: 2019-05

Variant appearance in text: SLCO2B1: 601G>A; rs35199625

PubMed Link: 30782852

Variant Present in the following documents:

• Main text

View BVdb publication page

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Genetic variation in human drug-related genes.

Genome Medicine

Schärfe, Charlotta Pauline Irmgard CPI; Tremmel, Roman R; Schwab, Matthias M; Kohlbacher, Oliver O; Marks, Debora Susan DS

Publication Date: 2017-12-22

Variant appearance in text: rs35199625

PubMed Link: 29273096

Variant Present in the following documents:

• 13073_2017_502_MOESM2_ESM.xlsx, sheet 2

View BVdb publication page

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Longitudinal analysis of treatment-induced genomic alterations in gliomas.

Genome Medicine

Erson-Omay, E Zeynep EZ; Henegariu, Octavian O; Omay, S Bülent SB; Harmancı, Akdes Serin AS; Youngblood, Mark W MW; Mishra-Gorur, Ketu K; Li, Jie J; Özduman, Koray K; Carrión-Grant, Geneive G; Clark, Victoria E VE; Çağlar, Caner C; Bakırcıoğlu, Mehmet M; Pamir, M Necmettin MN; Tabar, Viviane V; Vortmeyer, Alexander O AO; Bilguvar, Kaya K; Yasuno, Katsuhito K; DeAngelis, Lisa M LM; Baehring, Joachim M JM; Moliterno, Jennifer J; Günel, Murat M

Publication Date: 2017-02-02

Variant appearance in text: SLCO2B1: V201M

PubMed Link: 28153049

Variant Present in the following documents:

• 13073_2017_401_MOESM3_ESM.xlsx, sheet 2

View BVdb publication page

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Characterization of ADME gene variation in 21 populations by exome sequencing.

Pharmacogenetics And Genomics

Hovelson, Daniel H DH; Xue, Zhengyu Z; Zawistowski, Matthew M; Ehm, Margaret G MG; Harris, Elizabeth C EC; Stocker, Sophie L SL; Gross, Annette S AS; Jang, In-Jin IJ; Ieiri, Ichiro I; Lee, Jong-Eun JE; Cardon, Lon R LR; Chissoe, Stephanie L SL; Abecasis, Gonçalo G; Nelson, Matthew R MR

Publication Date: 2017-03

Variant appearance in text: SLCO2B1: 601G>A; rs35199625

PubMed Link: 27984508

Variant Present in the following documents:

• fpc-27-089-s005.xlsx, sheet 2
• fpc-27-089-s006.xlsx, sheet 2

View BVdb publication page

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Reproducible Analysis of Post-Translational Modifications in Proteomes--Application to Human Mutations.

Plos One

Holehouse, Alex S AS; Naegle, Kristen M KM

Publication Date: 2015

Variant appearance in text: rs35199625

PubMed Link: 26659599

Variant Present in the following documents:

• pone.0144692.s002.xlsx, sheet 1

View BVdb publication page

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Whole-genome sequencing of the world's oldest people.

Plos One

Gierman, Hinco J HJ; Fortney, Kristen K; Roach, Jared C JC; Coles, Natalie S NS; Li, Hong H; Glusman, Gustavo G; Markov, Glenn J GJ; Smith, Justin D JD; Hood, Leroy L; Coles, L Stephen LS; Kim, Stuart K SK

Publication Date: 2014

Variant appearance in text: SLCO2B1: V201M; rs35199625

PubMed Link: 25390934

Variant Present in the following documents:

• pone.0112430.s004.xlsx, sheet 1

View BVdb publication page

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The integrated landscape of driver genomic alterations in glioblastoma.

Nature Genetics

Frattini, Veronique V; Trifonov, Vladimir V; Chan, Joseph Minhow JM; Castano, Angelica A; Lia, Marie M; Abate, Francesco F; Keir, Stephen T ST; Ji, Alan X AX; Zoppoli, Pietro P; Niola, Francesco F; Danussi, Carla C; Dolgalev, Igor I; Porrati, Paola P; Pellegatta, Serena S; Heguy, Adriana A; Gupta, Gaurav G; Pisapia, David J DJ; Canoll, Peter P; Bruce, Jeffrey N JN; McLendon, Roger E RE; Yan, Hai H; Aldape, Ken K; Finocchiaro, Gaetano G; Mikkelsen, Tom T; Privé, Gilbert G GG; Bigner, Darell D DD; Lasorella, Anna A; Rabadan, Raul R; Iavarone, Antonio A

Publication Date: 2013-10

Variant appearance in text: SLCO2B1: V201M; rs35199625

PubMed Link: 23917401

Variant Present in the following documents:

• NIHMS510851-supplement-3.xlsx, sheet 1

View BVdb publication page

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SLCO2B1 genetic polymorphisms in a Korean population: pyrosequencing analyses and comprehensive comparison with other populations.

Molecular Biology Reports

Kim, Kyoung-Ah KA; Joo, Hyun-Jin HJ; Lee, Hae-Mi HM; Park, Ji-Young JY

Publication Date: 2013-07

Variant appearance in text: SLCO2B1: 601G>A; rs35199625

PubMed Link: 23666051

Variant Present in the following documents:

• Main text

View BVdb publication page

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Genetics is a major determinant of expression of the human hepatic uptake transporter OATP1B1, but not of OATP1B3 and OATP2B1.

Genome Medicine

Nies, Anne T AT; Niemi, Mikko M; Burk, Oliver O; Winter, Stefan S; Zanger, Ulrich M UM; Stieger, Bruno B; Schwab, Matthias M; Schaeffeler, Elke E

Publication Date: 2013

Variant appearance in text: SLCO2B1: 601G>A; rs35199625

PubMed Link: 23311897

Variant Present in the following documents:

• Main text
• gm405.pdf

View BVdb publication page

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Orange and apple juice greatly reduce the plasma concentrations of the OATP2B1 substrate aliskiren.

British Journal Of Clinical Pharmacology

Tapaninen, Tuija T; Neuvonen, Pertti J PJ; Niemi, Mikko M

Publication Date: 2011-05

Variant appearance in text: SLCO2B1: 601G>A; rs35199625

PubMed Link: 21204914

Variant Present in the following documents:

• Main text

View BVdb publication page

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