Variant ID: 12-102590890-T-G

NM_002674.2(PMCH):c.309A>C;(p.Lys103Asn)

This variant was identified in 10 publications




Publications:


High rates of transmitted NNRTI resistance among persons with acute HIV infection in Malawi: implications for first-line dolutegravir scale-up.

Aids Research And Therapy
SE Rutstein, JS Chen, JAE Nelson, S Phiri, WC Miller, MC Hosseinipour
Publication Date: 2019-02-22

Variant appearance in text: MCH: K103N
PubMed Link: 30795780
Variant Present in the following documents:
  • Main text
View BVdb publication page



HIV Drug Resistance in Adults Receiving Early vs. Delayed Antiretroviral Therapy: HPTN 052.

Journal Of Acquired Immune Deficiency Syndromes (1999)
PJ Palumbo, JM Fogel, SE Hudelson, EA Wilson, S Hart, L Hovind, E Piwowar-Manning, C Wallis, MA Papathanasopoulos, MG Morgado, S Saravanan, S Tripathy, JJ Eron, JE Gallant, M McCauley, T Gamble, MC Hosseinipour, N Kumarasamy, JG Hakim, JH Pilotto, J Kumwenda, V Akelo, SV Godbole, BR Santos, B Grinsztejn, R Panchia, S Chariyalertsak, J Makhema, S Badal-Faesen, YQ Chen, MS Cohen, SH Eshleman
Publication Date: 2018-04-15

Variant appearance in text: MCH: K103N
PubMed Link: 29293156
Variant Present in the following documents:
  • Main text
View BVdb publication page



Evaluation of mHealth strategies to optimize adherence and efficacy of Option B+ prevention of mother-to-child HIV transmission: Rationale, design and methods of a 3-armed randomized controlled trial.

Contemporary Clinical Trials
AL Drake, JA Unger, K Ronen, D Matemo, T Perrier, B DeRenzi, BA Richardson, J Kinuthia, G John-Stewart
Publication Date: 2017-06

Variant appearance in text: MCH: K103N
PubMed Link: 28315480
Variant Present in the following documents:
  • Main text
View BVdb publication page



Comparison of 454 Ultra-Deep Sequencing and Allele-Specific Real-Time PCR with Regard to the Detection of Emerging Drug-Resistant Minor HIV-1 Variants after Antiretroviral Prophylaxis for Vertical Transmission.

Plos One
A Hauser, C Kuecherer, A Kunz, PW Dabrowski, A Radonić, A Nitsche, S Theuring, N Bannert, J Sewangi, P Mbezi, F Dugange, G Harms, K Meixenberger
Publication Date: 2015

Variant appearance in text: MCH: K103N
PubMed Link: 26469189
Variant Present in the following documents:
  • 9789241599818_eng.pdf
  • pmtctguidelines3.pdf
View BVdb publication page



8th IAS Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2015).

Journal Of The International Aids Society
.
Publication Date: 2015

Variant appearance in text: MCH: K103N
PubMed Link: 26205488
Variant Present in the following documents:
  • Main text
View BVdb publication page



HIV-1 Genetic Variability and Clinical Implications.

Isrn Microbiology
MM Santoro, CF Perno
Publication Date: 2013

Variant appearance in text: MCH: K103N
PubMed Link: 23844315
Variant Present in the following documents:
  • 9789241599818_eng.pdf
View BVdb publication page



Clinical and genetic determinants of plasma nevirapine exposure following an intrapartum dose to prevent mother-to-child HIV transmission.

The Journal Of Infectious Diseases
S Vardhanabhuti, EP Acosta, HJ Ribaudo, P Severe, U Lalloo, N Kumarasamy, F Taulo, J Kabanda, O Oneko, P Ive, P Sambarey, ES Chan, J Hitti, F Hong, D McMahon, DW Haas,
Publication Date: 2013-08-15

Variant appearance in text: MCH: K103N
PubMed Link: 23687222
Variant Present in the following documents:
  • 9789241599818_eng.pdf
View BVdb publication page



Emergence of minor drug-resistant HIV-1 variants after triple antiretroviral prophylaxis for prevention of vertical HIV-1 transmission.

Plos One
A Hauser, J Sewangi, P Mbezi, F Dugange, I Lau, J Ziske, S Theuring, C Kuecherer, G Harms, A Kunz
Publication Date: 2012

Variant appearance in text: MCH: K103N
PubMed Link: 22384138
Variant Present in the following documents:
  • 9789241599818_eng.pdf
  • pmtctguidelines3.pdf
View BVdb publication page



Update on successes and challenges regarding mother-to-child transmission of HIV.

Current Opinion In Pediatrics
E Paintsil, WA Andiman
Publication Date: 2009-02

Variant appearance in text: MCH: K103N
PubMed Link: 19242245
Variant Present in the following documents:
  • Main text
View BVdb publication page



Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa.

Clinical Infectious Diseases : An Official Publication Of The Infectious Diseases Society Of America
VC Marconi, H Sunpath, Z Lu, M Gordon, K Koranteng-Apeagyei, J Hampton, S Carpenter, J Giddy, D Ross, H Holst, E Losina, BD Walker, DR Kuritzkes,
Publication Date: 2008-05-15

Variant appearance in text: MCH: K103N
PubMed Link: 18419495
Variant Present in the following documents:
  • Main text
View BVdb publication page



Alternative transcript annotations:

Transcript cDNA Protein Consequence Exon Intron
ENST00000327680.2 c.*821T>G - 3_prime_UTR_variant 12/12 -
ENST00000329406.4 c.309A>C p.Lys103Asn missense_variant 2/3 -
ENST00000378128.3 c.*1089T>G - 3_prime_UTR_variant 7/7 -
ENST00000412715.2 c.*1089T>G - 3_prime_UTR_variant 6/6 -
ENST00000417507.2 c.*1153T>G - 3_prime_UTR_variant 7/7 -
ENST00000457614.2 c.*1875T>G - 3_prime_UTR_variant,NMD_transcript_variant 8/8 -
ENST00000535811.1 n.1216T>G - non_coding_transcript_exon_variant 2/2 -
NM_001319988.1 c.*821T>G - 3_prime_UTR_variant 12/12 -
NM_001319993.1 c.*821T>G - 3_prime_UTR_variant 12/12 -
NM_001319994.1 c.*821T>G - 3_prime_UTR_variant 11/11 -
NM_002674.4 c.309A>C p.Lys103Asn missense_variant 2/3 -
NM_017915.4 c.*821T>G - 3_prime_UTR_variant 11/11 -
NR_135123.1 n.1760T>G - non_coding_transcript_exon_variant 5/5 -