IGF1 c.403-5895A>G

Variant ID: 12-102802239-T-C

NM_000618.3(IGF1):c.403-5895A>G

This variant was identified in 19 publications

View GRCh38 version.




Publications:


Identifying potential biomarkers for the diagnosis and treatment of IgA nephropathy based on bioinformatics analysis.

Bmc Medical Genomics
Li, Xiaohui X; Zeng, Mengru M; Liu, Jialu J; Zhang, Shumin S; Liu, Yifei Y; Zhao, Yuee Y; Wei, Cong C; Yang, Kexin K; Huang, Ying Y; Zhang, Lei L; Xiao, Li L
Publication Date: 2023-03-28

Variant appearance in text: rs978458
PubMed Link: 36978098
Variant Present in the following documents:
  • Main text
  • 12920_2023_Article_1494.pdf
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The G allele of the IGF1 rs2162679 SNP is a potential protective factor for any myopia: Updated systematic review and meta-analysis.

Plos One
Meng, Bo B; Wang, Kang K; Huang, Yingxiang Y; Wang, Yanling Y
Publication Date: 2022

Variant appearance in text: rs978458
PubMed Link: 35862416
Variant Present in the following documents:
  • Main text
  • pone.0271809.pdf
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Association of the Combined Effects between Insulin-Like Growth Factor-1 Gene Polymorphisms and Negative Life Events with Major Depressive Disorder among Chinese population in the Context of Oxidative Stress.

Oxidative Medicine And Cellular Longevity
Qiao, Zhengxue Z; Xie, Yunjia Y; Wu, Yongmei Y; Yang, Xiuxian X; Qiu, Xiaohui X; Zhou, Jiawei J; Lu, Yuxin Y; Chen, Lu L; Tong, Yuying Y; Xu, Jia J; Li, Jiarui J; He, Jingyun J; Pan, Hui H; Yang, Yanjie Y; Yang, Jiarun J; Bu, Tianyi T
Publication Date: 2022

Variant appearance in text: rs978458
PubMed Link: 35498133
Variant Present in the following documents:
  • OMCL2022-3253687.pdf
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Mammographic breast density and IGF-1 gene polymorphisms rs1520220, rs2946834 and rs6219 in Polish women.

Contemporary Oncology (Poznan, Poland)
Smolarz, Beata B; Połać, Ireneusz I; Romanowicz, Hanna H
Publication Date: 2021

Variant appearance in text: rs978458
PubMed Link: 34729039
Variant Present in the following documents:
  • Main text
  • WO-25-45368.pdf
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Single nucleotide polymorphisms of insulin-like growth factor gene and mammographic breast density.

Przeglad Menopauzalny = Menopause Review
Smolarz, Beata B; Wójcik, Luiza L; Romanowicz, Hanna H
Publication Date: 2020-12

Variant appearance in text: rs978458
PubMed Link: 33488326
Variant Present in the following documents:
  • MR-19-42759.pdf
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The 46th Annual Meeting of the European Society for Blood and Marrow Transplantation: Physicians Poster Session (P001-P706).

Bone Marrow Transplantation
Publication Date: 2020-12

Variant appearance in text: rs978458
PubMed Link: 33311612
Variant Present in the following documents:
  • Main text
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Mendelian randomization provides evidence for a causal effect of higher serum IGF-1 concentration on risk of hip and knee osteoarthritis.

Rheumatology (Oxford, England)
Hartley, April A; Sanderson, Eleanor E; Paternoster, Lavinia L; Teumer, Alexander A; Kaplan, Robert C RC; Tobias, Jon H JH; Gregson, Celia L CL
Publication Date: 2021-04-06

Variant appearance in text: rs978458
PubMed Link: 33027520
Variant Present in the following documents:
  • Main text
  • keaa597.pdf
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Insulin-Like Growth Factor Gene Polymorphisms Predict Clinical Course in Allogeneic Hematopoietic Stem Cell Transplantation.

Frontiers In Immunology
Ebbesen, Maria M; Enevold, Christian C; Juul, Anders A; Heilmann, Carsten C; Sengeløv, Henrik H; Müller, Klaus K
Publication Date: 2020

Variant appearance in text: rs978458
PubMed Link: 32793242
Variant Present in the following documents:
  • Main text
  • fimmu-11-01646.pdf
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IGF1 Gene Is Associated With Triglyceride Levels In Subjects With Family History Of Hypertension From The SAPPHIRe And TWB Projects.

International Journal Of Medical Sciences
Wang, Wen-Chang WC; Chiu, Yen-Feng YF; Chung, Ren-Hua RH; Hwu, Chii-Min CM; Lee, I-Te IT; Lee, Chien-Hsing CH; Chang, Yi-Cheng YC; Hung, Kuan-Yi KY; Quertermous, Thomas T; Chen, Yii-Der I YI; Hsiung, Chao A CA
Publication Date: 2018

Variant appearance in text: rs978458
PubMed Link: 30013445
Variant Present in the following documents:
  • Main text
  • ijmsv15p1035.pdf
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Circulating insulin-like growth factors and Alzheimer disease: A mendelian randomization study.

Neurology
Williams, Dylan M DM; Karlsson, Ida K IK; Pedersen, Nancy L NL; Hägg, Sara S
Publication Date: 2018-01-23

Variant appearance in text: rs978458
PubMed Link: 29282328
Variant Present in the following documents:
  • NEUROLOGY2017817544.pdf
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Investigation of DNA repair-related SNPs underlying susceptibility to papillary thyroid carcinoma reveals MGMT as a novel candidate gene in Belarusian children exposed to radiation.

Bmc Cancer
Lonjou, Christine C; Damiola, Francesca F; Moissonnier, Monika M; Durand, Geoffroy G; Malakhova, Irina I; Masyakin, Vladimir V; Le Calvez-Kelm, Florence F; Cardis, Elisabeth E; Byrnes, Graham G; Kesminiene, Ausrele A; Lesueur, Fabienne F
Publication Date: 2017-05-12

Variant appearance in text: rs978458
PubMed Link: 28499365
Variant Present in the following documents:
  • 12885_2017_3314_MOESM1_ESM.xls, sheet 1
View BVdb publication page



Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits.

Aging Cell
Teumer, Alexander A; Qi, Qibin Q; Nethander, Maria M; Aschard, Hugues H; Bandinelli, Stefania S; Beekman, Marian M; Berndt, Sonja I SI; Bidlingmaier, Martin M; Broer, Linda L; , ; Cappola, Anne A; Ceda, Gian Paolo GP; Chanock, Stephen S; Chen, Ming-Huei MH; Chen, Tai C TC; Chen, Yii-Der Ida YD; Chung, Jonathan J; Del Greco Miglianico, Fabiola F; Eriksson, Joel J; Ferrucci, Luigi L; Friedrich, Nele N; Gnewuch, Carsten C; Goodarzi, Mark O MO; Grarup, Niels N; Guo, Tingwei T; Hammer, Elke E; Hayes, Richard B RB; Hicks, Andrew A AA; Hofman, Albert A; Houwing-Duistermaat, Jeanine J JJ; Hu, Frank F; Hunter, David J DJ; Husemoen, Lise L LL; Isaacs, Aaron A; Jacobs, Kevin B KB; Janssen, Joop A M J L JA; Jansson, John-Olov JO; Jehmlich, Nico N; Johnson, Simon S; Juul, Anders A; Karlsson, Magnus M; Kilpelainen, Tuomas O TO; Kovacs, Peter P; Kraft, Peter P; Li, Chao C; Linneberg, Allan A; Liu, Yongmei Y; Loos, Ruth J F RJ; , ; Lorentzon, Mattias M; Lu, Yingchang Y; Maggio, Marcello M; Magi, Reedik R; Meigs, James J; Mellström, Dan D; Nauck, Matthias M; Newman, Anne B AB; Pollak, Michael N MN; Pramstaller, Peter P PP; Prokopenko, Inga I; Psaty, Bruce M BM; Reincke, Martin M; Rimm, Eric B EB; Rotter, Jerome I JI; Saint Pierre, Aude A; Schurmann, Claudia C; Seshadri, Sudha S; Sjögren, Klara K; Slagboom, P Eline PE; Strickler, Howard D HD; Stumvoll, Michael M; Suh, Yousin Y; Sun, Qi Q; Zhang, Cuilin C; Svensson, Johan J; Tanaka, Toshiko T; Tare, Archana A; Tönjes, Anke A; Uh, Hae-Won HW; van Duijn, Cornelia M CM; van Heemst, Diana D; Vandenput, Liesbeth L; Vasan, Ramachandran S RS; Völker, Uwe U; Willems, Sara M SM; Ohlsson, Claes C; Wallaschofski, Henri H; Kaplan, Robert C RC
Publication Date: 2016-10

Variant appearance in text: rs978458
PubMed Link: 27329260
Variant Present in the following documents:
  • Main text
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Assessing the role of insulin-like growth factors and binding proteins in prostate cancer using Mendelian randomization: Genetic variants as instruments for circulating levels.

International Journal Of Cancer
Bonilla, Carolina C; Lewis, Sarah J SJ; Rowlands, Mari-Anne MA; Gaunt, Tom R TR; Davey Smith, George G; Gunnell, David D; Palmer, Tom T; Donovan, Jenny L JL; Hamdy, Freddie C FC; Neal, David E DE; Eeles, Rosalind R; Easton, Doug D; Kote-Jarai, Zsofia Z; Al Olama, Ali Amin AA; Benlloch, Sara S; Muir, Kenneth K; Giles, Graham G GG; Wiklund, Fredrik F; Grönberg, Henrik H; Haiman, Christopher A CA; Schleutker, Johanna J; Nordestgaard, Børge G BG; Travis, Ruth C RC; Pashayan, Nora N; Khaw, Kay-Tee KT; Stanford, Janet L JL; Blot, William J WJ; Thibodeau, Stephen S; Maier, Christiane C; Kibel, Adam S AS; Cybulski, Cezary C; Cannon-Albright, Lisa L; Brenner, Hermann H; Park, Jong J; Kaneva, Radka R; Batra, Jyotsna J; Teixeira, Manuel R MR; Pandha, Hardev H; , ; Lathrop, Mark M; Martin, Richard M RM; Holly, Jeff M P JM
Publication Date: 2016-10-01

Variant appearance in text: rs978458
PubMed Link: 27225428
Variant Present in the following documents:
  • Main text
  • IJC-139-1520.pdf
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Assessment of age-related changes in heritability and IGF-1 gene effect on circulating IGF-1 levels.

Age (Dordrecht, Netherlands)
Franco, Liran L; Williams, Frances M K FM; Trofimov, Svetlana S; Malkin, Ida I; Surdulescu, Gabriela G; Spector, Timothy T; Livshits, Gregory G
Publication Date: 2014-06

Variant appearance in text: rs978458
PubMed Link: 24493200
Variant Present in the following documents:
  • Main text
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Insulin-like growth factor 1 is not associated with high myopia in a large Japanese cohort.

Molecular Vision
Miyake, Masahiro M; Yamashiro, Kenji K; Nakanishi, Hideo H; Nakata, Isao I; Akagi-Kurashige, Yumiko Y; Tsujikawa, Akitaka A; Moriyama, Muka M; Ohno-Matsui, Kyoko K; Mochizuki, Manabu M; Yamada, Ryo R; Matsuda, Fumihiko F; Yoshimura, Nagahisa N
Publication Date: 2013

Variant appearance in text: rs978458
PubMed Link: 23734076
Variant Present in the following documents:
  • Main text
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Polymorphisms of IGFI contribute to the development of ischemic stroke.

Experimental And Therapeutic Medicine
Kim, Hak Jae HJ; Kim, Su Kang SK; Park, Hae Jeong HJ; Chung, Joo-Ho JH; Chun, Jinman J; Yun, Dong Hwan DH; Kim, Young Ock YO
Publication Date: 2012-01

Variant appearance in text: rs978458
PubMed Link: 22969851
Variant Present in the following documents:
  • Main text
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Fetal growth and body size genes and risk of childhood acute lymphoblastic leukemia.

Cancer Causes & Control : Ccc
Chokkalingam, Anand P AP; Metayer, Catherine C; Scelo, Ghislaine G; Chang, Jeffrey S JS; Schiffman, Joshua J; Urayama, Kevin Y KY; Ma, Xiaomei X; Hansen, Helen M HM; Feusner, James H JH; Barcellos, Lisa F LF; Wiencke, John K JK; Wiemels, Joseph L JL; Buffler, Patricia A PA
Publication Date: 2012-09

Variant appearance in text: rs978458
PubMed Link: 22878902
Variant Present in the following documents:
  • 10552_2012_Article_35.pdf
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Prospective study of insulin-like growth factor-I, insulin-like growth factor-binding protein 3, genetic variants in the IGF1 and IGFBP3 genes and risk of coronary artery disease.

International Journal Of Molecular Epidemiology And Genetics
Ricketts, Sally L SL; Rensing, Katrijn L KL; Holly, Jeff M JM; Chen, Li L; Young, Elizabeth H EH; Luben, Robert R; Ashford, Sofie S; Song, Kijoung K; Yuan, Xin X; Dehghan, Abbas A; Wright, Benjamin J BJ; Waterworth, Dawn M DM; Mooser, Vincent V; , ; Waeber, Gérard G; Vollenweider, Peter P; Epstein, Stephen E SE; Burnett, Mary S MS; Devaney, Joseph M JM; Hakonarson, Hakon H HH; Rader, Daniel J DJ; Reilly, Muredach P MP; Danesh, John J; Thompson, Simon G SG; Dunning, Alison M AM; van Duijn, Cornelia M CM; Samani, Nilesh J NJ; McPherson, Ruth R; Wareham, Nicholas J NJ; Khaw, Kay-Tee KT; Boekholdt, S Matthijs SM; Sandhu, Manjinder S MS
Publication Date: 2011-08-30

Variant appearance in text: rs978458
PubMed Link: 21915365
Variant Present in the following documents:
  • Main text
View BVdb publication page



IGF-I and IGFBP-3 polymorphisms in relation to circulating levels among African American and Caucasian women.

Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology
D'Aloisio, Aimee A AA; Schroeder, Jane C JC; North, Kari E KE; Poole, Charles C; West, Suzanne L SL; Travlos, Gregory S GS; Baird, Donna D DD
Publication Date: 2009-03

Variant appearance in text: rs978458
PubMed Link: 19240240
Variant Present in the following documents:
  • Main text
View BVdb publication page