IGF1 c.220+4996G>T

Variant ID: 12-102864425-C-A

NM_000618.3(IGF1):c.220+4996G>T

This variant was identified in 22 publications

View GRCh38 version.




Publications:


The Insulin-like Growth Factor System and Colorectal Cancer.

Life (Basel, Switzerland)
Gligorijević, Nikola N; Dobrijević, Zorana Z; Šunderić, Miloš M; Robajac, Dragana D; Četić, Danilo D; Penezić, Ana A; Miljuš, Goran G; Nedić, Olgica O
Publication Date: 2022-08-20

Variant appearance in text: rs1019731
PubMed Link: 36013453
Variant Present in the following documents:
  • Main text
  • life-12-01274.pdf
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Dual Characters of GH-IGF1 Signaling Pathways in Radiotherapy and Post-radiotherapy Repair of Cancers.

Frontiers In Cell And Developmental Biology
Cheng, Yunyun Y; Li, Wanqiao W; Gui, Ruirui R; Wang, Chunli C; Song, Jie J; Wang, Zhaoguo Z; Wang, Xue X; Shen, Yannan Y; Wang, Zhicheng Z; Hao, Linlin L
Publication Date: 2021

Variant appearance in text: rs1019731
PubMed Link: 34178997
Variant Present in the following documents:
  • Main text
  • fcell-09-671247.pdf
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Development of a Genetic Risk Score to predict the risk of overweight and obesity in European adolescents from the HELENA study.

Scientific Reports
Seral-Cortes, Miguel M; Sabroso-Lasa, Sergio S; De Miguel-Etayo, Pilar P; Gonzalez-Gross, Marcela M; Gesteiro, Eva E; Molina-Hidalgo, Cristina C; De Henauw, Stefaan S; Gottrand, Frederic F; Mavrogianni, Christina C; Manios, Yannis Y; Plada, Maria M; Widhalm, Kurt K; Kafatos, Anthony A; Erhardt, Éva É; Meirhaeghe, Aline A; Salazar-Tortosa, Diego D; Ruiz, Jonatan J; Moreno, Luis A LA; Esteban, Luis Mariano LM; Labayen, Idoia I
Publication Date: 2021-02-04

Variant appearance in text: rs1019731
PubMed Link: 33542408
Variant Present in the following documents:
  • Main text
  • 41598_2021_Article_82712.pdf
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Polymorphisms of Insulin-Like Growth Factor 1 Pathway Genes and Breast Cancer Risk.

Frontiers In Oncology
Shi, Joy J; Aronson, Kristan J KJ; Grundy, Anne A; Kobayashi, Lindsay C LC; Burstyn, Igor I; Schuetz, Johanna M JM; Lohrisch, Caroline A CA; SenGupta, Sandip K SK; Lai, Agnes S AS; Brooks-Wilson, Angela A; Spinelli, John J JJ; Richardson, Harriet H
Publication Date: 2016

Variant appearance in text: rs1019731
PubMed Link: 27376028
Variant Present in the following documents:
  • Main text
  • fonc-06-00136.pdf
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Assessment of age-related changes in heritability and IGF-1 gene effect on circulating IGF-1 levels.

Age (Dordrecht, Netherlands)
Franco, Liran L; Williams, Frances M K FM; Trofimov, Svetlana S; Malkin, Ida I; Surdulescu, Gabriela G; Spector, Timothy T; Livshits, Gregory G
Publication Date: 2014-06

Variant appearance in text: rs1019731
PubMed Link: 24493200
Variant Present in the following documents:
  • Main text
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Genomic markers of ovarian reserve.

Seminars In Reproductive Medicine
Wood, Michelle A MA; Rajkovic, Aleksandar A
Publication Date: 2013-11

Variant appearance in text: rs1019731
PubMed Link: 24101221
Variant Present in the following documents:
  • Main text
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Genetic variation and reproductive timing: African American women from the Population Architecture using Genomics and Epidemiology (PAGE) Study.

Plos One
Spencer, Kylee L KL; Malinowski, Jennifer J; Carty, Cara L CL; Franceschini, Nora N; Fernández-Rhodes, Lindsay L; Young, Alicia A; Cheng, Iona I; Ritchie, Marylyn D MD; Haiman, Christopher A CA; Wilkens, Lynne L; Chunyuanwu, ; Matise, Tara C TC; Carlson, Christopher S CS; Brennan, Kathleen K; Park, Amy A; Rajkovic, Aleksandar A; Hindorff, Lucia A LA; Buyske, Steven S; Crawford, Dana C DC
Publication Date: 2013

Variant appearance in text: rs1019731
PubMed Link: 23424626
Variant Present in the following documents:
  • Main text
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The insulin and igf-I pathway in endocrine glands carcinogenesis.

Journal Of Oncology
Malaguarnera, Roberta R; Morcavallo, Alaide A; Belfiore, Antonino A
Publication Date: 2012

Variant appearance in text: rs1019731
PubMed Link: 22927847
Variant Present in the following documents:
  • Main text
  • JO2012-635614.pdf
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Genetic variability in IGF-1 and IGFBP-3 and body size in early life.

Bmc Public Health
Poole, Elizabeth M EM; Tworoger, Shelley S SS; Hankinson, Susan E SE; Baer, Heather J HJ
Publication Date: 2012-08-15

Variant appearance in text: rs1019731
PubMed Link: 22894543
Variant Present in the following documents:
  • Main text
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Fetal growth and body size genes and risk of childhood acute lymphoblastic leukemia.

Cancer Causes & Control : Ccc
Chokkalingam, Anand P AP; Metayer, Catherine C; Scelo, Ghislaine G; Chang, Jeffrey S JS; Schiffman, Joshua J; Urayama, Kevin Y KY; Ma, Xiaomei X; Hansen, Helen M HM; Feusner, James H JH; Barcellos, Lisa F LF; Wiencke, John K JK; Wiemels, Joseph L JL; Buffler, Patricia A PA
Publication Date: 2012-09

Variant appearance in text: rs1019731
PubMed Link: 22878902
Variant Present in the following documents:
  • Main text
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ESR1, HK3 and BRSK1 gene variants are associated with both age at natural menopause and premature ovarian failure.

Orphanet Journal Of Rare Diseases
Qin, Yingying Y; Sun, Mei M; You, Li L; Wei, Deying D; Sun, Jielin J; Liang, Xiaoyan X; Zhang, Bo B; Jiang, Hong H; Xu, Jianfeng J; Chen, Zi-Jiang ZJ
Publication Date: 2012-01-17

Variant appearance in text: rs1019731
PubMed Link: 22248077
Variant Present in the following documents:
  • Main text
  • 1750-1172-7-5.pdf
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Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height.

American Journal Of Human Genetics
Lanktree, Matthew B MB; Guo, Yiran Y; Murtaza, Muhammed M; Glessner, Joseph T JT; Bailey, Swneke D SD; Onland-Moret, N Charlotte NC; Lettre, Guillaume G; Ongen, Halit H; Rajagopalan, Ramakrishnan R; Johnson, Toby T; Shen, Haiqing H; Nelson, Christopher P CP; Klopp, Norman N; Baumert, Jens J; Padmanabhan, Sandosh S; Pankratz, Nathan N; Pankow, James S JS; Shah, Sonia S; Taylor, Kira K; Barnard, John J; Peters, Bas J BJ; Maloney, Cliona M CM; Lobmeyer, Maximilian T MT; Stanton, Alice A; Zafarmand, M Hadi MH; Romaine, Simon P R SP; Mehta, Amar A; van Iperen, Erik P A EP; Gong, Yan Y; Price, Tom S TS; Smith, Erin N EN; Kim, Cecilia E CE; Li, Yun R YR; Asselbergs, Folkert W FW; Atwood, Larry D LD; Bailey, Kristian M KM; Bhatt, Deepak D; Bauer, Florianne F; Behr, Elijah R ER; Bhangale, Tushar T; Boer, Jolanda M A JM; Boehm, Bernhard O BO; Bradfield, Jonathan P JP; Brown, Morris M; Braund, Peter S PS; Burton, Paul R PR; Carty, Cara C; Chandrupatla, Hareesh R HR; Chen, Wei W; Connell, John J; Dalgeorgou, Chrysoula C; Boer, Anthonius de Ad; Drenos, Fotios F; Elbers, Clara C CC; Fang, James C JC; Fox, Caroline S CS; Frackelton, Edward C EC; Fuchs, Barry B; Furlong, Clement E CE; Gibson, Quince Q; Gieger, Christian C; Goel, Anuj A; Grobbee, Diederik E DE; Hastie, Claire C; Howard, Philip J PJ; Huang, Guan-Hua GH; Johnson, W Craig WC; Li, Qing Q; Kleber, Marcus E ME; Klein, Barbara E K BE; Klein, Ronald R; Kooperberg, Charles C; Ky, Bonnie B; Lacroix, Andrea A; Lanken, Paul P; Lathrop, Mark M; Li, Mingyao M; Marshall, Vanessa V; Melander, Olle O; Mentch, Frank D FD; Meyer, Nuala J NJ; Monda, Keri L KL; Montpetit, Alexandre A; Murugesan, Gurunathan G; Nakayama, Karen K; Nondahl, Dave D; Onipinla, Abiodun A; Rafelt, Suzanne S; Newhouse, Stephen J SJ; Otieno, F George FG; Patel, Sanjey R SR; Putt, Mary E ME; Rodriguez, Santiago S; Safa, Radwan N RN; Sawyer, Douglas B DB; Schreiner, Pamela J PJ; Simpson, Claire C; Sivapalaratnam, Suthesh S; Srinivasan, Sathanur R SR; Suver, Christine C; Swergold, Gary G; Sweitzer, Nancy K NK; Thomas, Kelly A KA; Thorand, Barbara B; Timpson, Nicholas J NJ; Tischfield, Sam S; Tobin, Martin M; Tomaszewski, Maciej M; Tomaszweski, Maciej M; Verschuren, W M Monique WM; Wallace, Chris C; Winkelmann, Bernhard B; Zhang, Haitao H; Zheng, Dongling D; Zhang, Li L; Zmuda, Joseph M JM; Clarke, Robert R; Balmforth, Anthony J AJ; Danesh, John J; Day, Ian N IN; Schork, Nicholas J NJ; de Bakker, Paul I W PI; Delles, Christian C; Duggan, David D; Hingorani, Aroon D AD; Hirschhorn, Joel N JN; Hofker, Marten H MH; Humphries, Steve E SE; Kivimaki, Mika M; Lawlor, Debbie A DA; Kottke-Marchant, Kandice K; Mega, Jessica L JL; Mitchell, Braxton D BD; Morrow, David A DA; Palmen, Jutta J; Redline, Susan S; Shields, Denis C DC; Shuldiner, Alan R AR; Sleiman, Patrick M PM; Smith, George Davey GD; Farrall, Martin M; Jamshidi, Yalda Y; Christiani, David C DC; Casas, Juan P JP; Hall, Alistair S AS; Doevendans, Pieter A PA; Christie, Jason D JD; Berenson, Gerald S GS; Murray, Sarah S SS; Illig, Thomas T; Dorn, Gerald W GW; Cappola, Thomas P TP; Boerwinkle, Eric E; Sever, Peter P; Rader, Daniel J DJ; Reilly, Muredach P MP; Caulfield, Mark M; Talmud, Philippa J PJ; Topol, Eric E; Engert, James C JC; Wang, Kai K; Dominiczak, Anna A; Hamsten, Anders A; Curtis, Sean P SP; Silverstein, Roy L RL; Lange, Leslie A LA; Sabatine, Marc S MS; Trip, Mieke M; Saleheen, Danish D; Peden, John F JF; Cruickshanks, Karen J KJ; März, Winfried W; O'Connell, Jeffrey R JR; Klungel, Olaf H OH; Wijmenga, Cisca C; Maitland-van der Zee, Anke Hilse AH; Schadt, Eric E EE; Johnson, Julie A JA; Jarvik, Gail P GP; Papanicolaou, George J GJ; , ; Grant, Struan F A SF; Munroe, Patricia B PB; North, Kari E KE; Samani, Nilesh J NJ; Koenig, Wolfgang W; Gaunt, Tom R TR; Anand, Sonia S SS; van der Schouw, Yvonne T YT; , ; Soranzo, Nicole N; Fitzgerald, Garret A GA; Reiner, Alex A; Hegele, Robert A RA; Hakonarson, Hakon H; Keating, Brendan J BJ
Publication Date: 2011-01-07

Variant appearance in text: rs1019731
PubMed Link: 21194676
Variant Present in the following documents:
  • Main text
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Common genetic variation within IGFI, IGFII, IGFBP-1, and IGFBP-3 and endometrial cancer risk.

Gynecologic Oncology
McGrath, Monica M; Lee, I-Min IM; Buring, Julie J; De Vivo, Immaculata I
Publication Date: 2011-02

Variant appearance in text: rs1019731
PubMed Link: 21078522
Variant Present in the following documents:
  • Main text
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A large-scale candidate gene association study of age at menarche and age at natural menopause.

Human Genetics
He, Chunyan C; Kraft, Peter P; Chasman, Daniel I DI; Buring, Julie E JE; Chen, Constance C; Hankinson, Susan E SE; Paré, Guillaume G; Chanock, Stephen S; Ridker, Paul M PM; Hunter, David J DJ
Publication Date: 2010-11

Variant appearance in text: rs1019731
PubMed Link: 20734064
Variant Present in the following documents:
  • Main text
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Genetic association of insulin-like growth factor-1 polymorphisms with high-grade myopia in an international family cohort.

Investigative Ophthalmology & Visual Science
Metlapally, Ravikanth R; Ki, Chang-Seok CS; Li, Yi-Ju YJ; Tran-Viet, Khanh-Nhat KN; Abbott, Diana D; Malecaze, Francois F; Calvas, Patrick P; Mackey, David A DA; Rosenberg, Thomas T; Paget, Sandrine S; Guggenheim, Jeremy A JA; Young, Terri L TL
Publication Date: 2010-09

Variant appearance in text: rs1019731
PubMed Link: 20435602
Variant Present in the following documents:
  • Main text
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Common genetic variation in IGF1, IGFBP1 and IGFBP3 and ovarian cancer risk.

Carcinogenesis
Terry, Kathryn L KL; Tworoger, Shelley S SS; Gates, Margaret A MA; Cramer, Daniel W DW; Hankinson, Susan E SE
Publication Date: 2009-12

Variant appearance in text: rs1019731
PubMed Link: 19858071
Variant Present in the following documents:
  • Main text
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Genetic variation and circulating levels of IGF-I and IGFBP-3 in relation to risk of proliferative benign breast disease.

International Journal Of Cancer
Su, Xuefen X; Colditz, Graham A GA; Willett, Walter C WC; Collins, Laura C LC; Schnitt, Stuart J SJ; Connolly, James L JL; Pollak, Michael N MN; Rosner, Bernard B; Tamimi, Rulla M RM
Publication Date: 2010-01-01

Variant appearance in text: rs1019731
PubMed Link: 19551864
Variant Present in the following documents:
  • Main text
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IGF-I and IGFBP-3 polymorphisms in relation to circulating levels among African American and Caucasian women.

Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology
D'Aloisio, Aimee A AA; Schroeder, Jane C JC; North, Kari E KE; Poole, Charles C; West, Suzanne L SL; Travlos, Gregory S GS; Baird, Donna D DD
Publication Date: 2009-03

Variant appearance in text: rs1019731
PubMed Link: 19240240
Variant Present in the following documents:
  • Main text
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Insulin-like growth factor-1- and interleukin-6-related gene variation and risk of multiple myeloma.

Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology
Birmann, Brenda M BM; Tamimi, Rulla M RM; Giovannucci, Edward E; Rosner, Bernard B; Hunter, David J DJ; Kraft, Peter P; Mitsiades, Constantine C; Anderson, Kenneth C KC; Colditz, Graham A GA
Publication Date: 2009-01

Variant appearance in text: rs1019731
PubMed Link: 19124510
Variant Present in the following documents:
  • Main text
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Can genes for mammographic density inform cancer aetiology?

Nature Reviews. Cancer
Kelemen, Linda E LE; Sellers, Thomas A TA; Vachon, Celine M CM
Publication Date: 2008-10

Variant appearance in text: rs1019731
PubMed Link: 18772892
Variant Present in the following documents:
  • Main text
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IGF-1, IGFBP-1, and IGFBP-3 polymorphisms predict circulating IGF levels but not breast cancer risk: findings from the Breast and Prostate Cancer Cohort Consortium (BPC3).

Plos One
Patel, Alpa V AV; Cheng, Iona I; Canzian, Federico F; Le Marchand, Loïc L; Thun, Michael J MJ; Berg, Christine D CD; Buring, Julie J; Calle, Eugenia E EE; Chanock, Stephen S; Clavel-Chapelon, Francoise F; Cox, David G DG; Dorronsoro, Miren M; Dossus, Laure L; Haiman, Christopher A CA; Hankinson, Susan E SE; Henderson, Brian E BE; Hoover, Robert R; Hunter, David J DJ; Kaaks, Rudolf R; Kolonel, Laurence N LN; Kraft, Peter P; Linseisen, Jakob J; Lund, Eiliv E; Manjer, Jonas J; McCarty, Catherine C; Peeters, Petra H M PH; Pike, Malcolm C MC; Pollak, Michael M; Riboli, Elio E; Stram, Daniel O DO; Tjonneland, Anne A; Travis, Ruth C RC; Trichopoulos, Dimitrios D; Tumino, Rosario R; Yeager, Meredith M; Ziegler, Regina G RG; Feigelson, Heather Spencer HS; ,
Publication Date: 2008-07-02

Variant appearance in text: rs1019731
PubMed Link: 18596909
Variant Present in the following documents:
  • Main text
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Common genetic variation in IGF1, IGFBP-1, and IGFBP-3 in relation to mammographic density: a cross-sectional study.

Breast Cancer Research : Bcr
Tamimi, Rulla M RM; Cox, David G DG; Kraft, Peter P; Pollak, Michael N MN; Haiman, Christopher A CA; Cheng, Iona I; Freedman, Matthew L ML; Hankinson, Susan E SE; Hunter, David J DJ; Colditz, Graham A GA
Publication Date: 2007

Variant appearance in text: rs1019731
PubMed Link: 17300730
Variant Present in the following documents:
  • Main text
  • bcr1655.pdf
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