Loss of heterozygosity of essential genes represents a widespread class of potential cancer vulnerabilities.
Nature Communications
Nichols, Caitlin A CA; Gibson, William J WJ; Brown, Meredith S MS; Kosmicki, Jack A JA; Busanovich, John P JP; Wei, Hope H; Urbanski, Laura M LM; Curimjee, Naomi N; Berger, Ashton C AC; Gao, Galen F GF; Cherniack, Andrew D AD; Dhe-Paganon, Sirano S; Paolella, Brenton R BR; Beroukhim, Rameen R
Tissue-specific genetic control of splicing: implications for the study of complex traits.
Plos Biology
Heinzen, Erin L EL; Ge, Dongliang D; Cronin, Kenneth D KD; Maia, Jessica M JM; Shianna, Kevin V KV; Gabriel, Willow N WN; Welsh-Bohmer, Kathleen A KA; Hulette, Christine M CM; Denny, Thomas N TN; Goldstein, David B DB
Common variants at 30 loci contribute to polygenic dyslipidemia.
Nature Genetics
Kathiresan, Sekar S; Willer, Cristen J CJ; Peloso, Gina M GM; Demissie, Serkalem S; Musunuru, Kiran K; Schadt, Eric E EE; Kaplan, Lee L; Bennett, Derrick D; Li, Yun Y; Tanaka, Toshiko T; Voight, Benjamin F BF; Bonnycastle, Lori L LL; Jackson, Anne U AU; Crawford, Gabriel G; Surti, Aarti A; Guiducci, Candace C; Burtt, Noel P NP; Parish, Sarah S; Clarke, Robert R; Zelenika, Diana D; Kubalanza, Kari A KA; Morken, Mario A MA; Scott, Laura J LJ; Stringham, Heather M HM; Galan, Pilar P; Swift, Amy J AJ; Kuusisto, Johanna J; Bergman, Richard N RN; Sundvall, Jouko J; Laakso, Markku M; Ferrucci, Luigi L; Scheet, Paul P; Sanna, Serena S; Uda, Manuela M; Yang, Qiong Q; Lunetta, Kathryn L KL; Dupuis, Josée J; de Bakker, Paul I W PI; O'Donnell, Christopher J CJ; Chambers, John C JC; Kooner, Jaspal S JS; Hercberg, Serge S; Meneton, Pierre P; Lakatta, Edward G EG; Scuteri, Angelo A; Schlessinger, David D; Tuomilehto, Jaakko J; Collins, Francis S FS; Groop, Leif L; Altshuler, David D; Collins, Rory R; Lathrop, G Mark GM; Melander, Olle O; Salomaa, Veikko V; Peltonen, Leena L; Orho-Melander, Marju M; Ordovas, Jose M JM; Boehnke, Michael M; Abecasis, Gonçalo R GR; Mohlke, Karen L KL; Cupples, L Adrienne LA