Assessing the Relationship Between High-sensitivity C-reactive Protein and Kidney Function Employing Mendelian Randomization in the Japanese Community-based J-MICC Study.
Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease.
Nature Communications
Nielsen, Jonas B JB; Rom, Oren O; Surakka, Ida I; Graham, Sarah E SE; Zhou, Wei W; Roychowdhury, Tanmoy T; Fritsche, Lars G LG; Gagliano Taliun, Sarah A SA; Sidore, Carlo C; Liu, Yuhao Y; Gabrielsen, Maiken E ME; Skogholt, Anne Heidi AH; Wolford, Brooke B; Overton, William W; Zhao, Ying Y; Chen, Jin J; Zhang, He H; Hornsby, Whitney E WE; Acheampong, Akua A; Grooms, Austen A; Schaefer, Amanda A; Zajac, Gregory J M GJM; Villacorta, Luis L; Zhang, Jifeng J; Brumpton, Ben B; Løset, Mari M; Rai, Vivek V; Lundegaard, Pia R PR; Olesen, Morten S MS; Taylor, Kent D KD; Palmer, Nicholette D ND; Chen, Yii-Der YD; Choi, Seung H SH; Lubitz, Steven A SA; Ellinor, Patrick T PT; Barnes, Kathleen C KC; Daya, Michelle M; Rafaels, Nicholas N; Weiss, Scott T ST; Lasky-Su, Jessica J; Tracy, Russell P RP; Vasan, Ramachandran S RS; Cupples, L Adrienne LA; Mathias, Rasika A RA; Yanek, Lisa R LR; Becker, Lewis C LC; Peyser, Patricia A PA; Bielak, Lawrence F LF; Smith, Jennifer A JA; Aslibekyan, Stella S; Hidalgo, Bertha A BA; Arnett, Donna K DK; Irvin, Marguerite R MR; Wilson, James G JG; Musani, Solomon K SK; Correa, Adolfo A; Rich, Stephen S SS; Guo, Xiuqing X; Rotter, Jerome I JI; Konkle, Barbara A BA; Johnsen, Jill M JM; Ashley-Koch, Allison E AE; Telen, Marilyn J MJ; Sheehan, Vivien A VA; Blangero, John J; Curran, Joanne E JE; Peralta, Juan M JM; Montgomery, Courtney C; Sheu, Wayne H-H WH; Chung, Ren-Hua RH; Schwander, Karen K; Nouraie, Seyed M SM; Gordeuk, Victor R VR; Zhang, Yingze Y; Kooperberg, Charles C; Reiner, Alexander P AP; Jackson, Rebecca D RD; Bleecker, Eugene R ER; Meyers, Deborah A DA; Li, Xingnan X; Das, Sayantan S; Yu, Ketian K; LeFaive, Jonathon J; Smith, Albert A; Blackwell, Tom T; Taliun, Daniel D; Zollner, Sebastian S; Forer, Lukas L; Schoenherr, Sebastian S; Fuchsberger, Christian C; Pandit, Anita A; Zawistowski, Matthew M; Kheterpal, Sachin S; Brummett, Chad M CM; Natarajan, Pradeep P; Schlessinger, David D; Lee, Seunggeun S; Kang, Hyun Min HM; Cucca, Francesco F; Holmen, Oddgeir L OL; Åsvold, Bjørn O BO; Boehnke, Michael M; Kathiresan, Sekar S; Abecasis, Goncalo R GR; Chen, Y Eugene YE; Willer, Cristen J CJ; Hveem, Kristian K
Genome-wide association study of high-sensitivity C-reactive protein, D-dimer, and interleukin-6 levels in multiethnic HIV+ cohorts.
Aids (London, England)
Sherman, Brad T BT; Hu, Xiaojun X; Singh, Kanal K; Haine, Lillian L; Rupert, Adam W AW; Neaton, James D JD; Lundgren, Jens D JD; Imamichi, Tomozumi T; Chang, Weizhong W; Lane, H Clifford HC; ,
Common and Rare Sequence Variants Influencing Tumor Biomarkers in Blood.
Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology
Olafsson, Sigurgeir S; Alexandersson, Kristjan F KF; Gizurarson, Johann G K JGK; Hauksdottir, Katrin K; Gunnarsson, Orvar O; Olafsson, Karl K; Gudmundsson, Julius J; Stacey, Simon N SN; Sveinbjornsson, Gardar G; Saemundsdottir, Jona J; Bjornsson, Einar S ES; Olafsson, Sigurdur S; Bjornsson, Sigurdur S; Orvar, Kjartan B KB; Vikingsson, Arnor A; Geirsson, Arni J AJ; Arinbjarnarson, Sturla S; Bjornsdottir, Gyda G; Thorgeirsson, Thorgeir E TE; Sigurdsson, Snaevar S; Halldorsson, Gisli H GH; Magnusson, Olafur T OT; Masson, Gisli G; Holm, Hilma H; Jonsdottir, Ingileif I; Sigurdardottir, Olof O; Eyjolfsson, Gudmundur I GI; Olafsson, Isleifur I; Sulem, Patrick P; Thorsteinsdottir, Unnur U; Jonsson, Thorvaldur T; Rafnar, Thorunn T; Gudbjartsson, Daniel F DF; Stefansson, Kari K
Genetic analysis of hsCRP in American Indians: The Strong Heart Family Study.
Plos One
Best, Lyle G LG; Balakrishnan, Poojitha P; Cole, Shelley A SA; Haack, Karin K; Kocarnik, Jonathan M JM; Pankratz, Nathan N; Anderson, Matthew Z MZ; Franceschini, Nora N; Howard, Barbara V BV; Lee, Elisa T ET; North, Kari E KE; Umans, Jason G JG; Yracheta, Joseph M JM; Navas-Acien, Ana A; Voruganti, V Saroja VS
Mycophenolic Acid and Its Metabolites in Kidney Transplant Recipients: A Semimechanistic Enterohepatic Circulation Model to Improve Estimating Exposure.
Journal Of Clinical Pharmacology
Okour, Malek M; Jacobson, Pamala A PA; Ahmed, Mariam A MA; Israni, Ajay K AK; Brundage, Richard C RC
Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.
Nature Genetics
Phelan, Catherine M CM; Kuchenbaecker, Karoline B KB; Tyrer, Jonathan P JP; Kar, Siddhartha P SP; Lawrenson, Kate K; Winham, Stacey J SJ; Dennis, Joe J; Pirie, Ailith A; Riggan, Marjorie J MJ; Chornokur, Ganna G; Earp, Madalene A MA; Lyra, Paulo C PC; Lee, Janet M JM; Coetzee, Simon S; Beesley, Jonathan J; McGuffog, Lesley L; Soucy, Penny P; Dicks, Ed E; Lee, Andrew A; Barrowdale, Daniel D; Lecarpentier, Julie J; Leslie, Goska G; Aalfs, Cora M CM; Aben, Katja K H KKH; Adams, Marcia M; Adlard, Julian J; Andrulis, Irene L IL; Anton-Culver, Hoda H; Antonenkova, Natalia N; , ; Aravantinos, Gerasimos G; Arnold, Norbert N; Arun, Banu K BK; Arver, Brita B; Azzollini, Jacopo J; Balmaña, Judith J; Banerjee, Susana N SN; Barjhoux, Laure L; Barkardottir, Rosa B RB; Bean, Yukie Y; Beckmann, Matthias W MW; Beeghly-Fadiel, Alicia A; Benitez, Javier J; Bermisheva, Marina M; Bernardini, Marcus Q MQ; Birrer, Michael J MJ; Bjorge, Line L; Black, Amanda A; Blankstein, Kenneth K; Blok, Marinus J MJ; Bodelon, Clara C; Bogdanova, Natalia N; Bojesen, Anders A; Bonanni, Bernardo B; Borg, Åke Å; Bradbury, Angela R AR; Brenton, James D JD; Brewer, Carole C; Brinton, Louise L; Broberg, Per P; Brooks-Wilson, Angela A; Bruinsma, Fiona F; Brunet, Joan J; Buecher, Bruno B; Butzow, Ralf R; Buys, Saundra S SS; Caldes, Trinidad T; Caligo, Maria A MA; Campbell, Ian I; Cannioto, Rikki R; Carney, Michael E ME; Cescon, Terence T; Chan, Salina B SB; Chang-Claude, Jenny J; Chanock, Stephen S; Chen, Xiao Qing XQ; Chiew, Yoke-Eng YE; Chiquette, Jocelyne J; Chung, Wendy K WK; Claes, Kathleen B M KBM; Conner, Thomas T; Cook, Linda S LS; Cook, Jackie J; Cramer, Daniel W DW; Cunningham, Julie M JM; D'Aloisio, Aimee A AA; Daly, Mary B MB; Damiola, Francesca F; Damirovna, Sakaeva Dina SD; Dansonka-Mieszkowska, Agnieszka A; Dao, Fanny F; Davidson, Rosemarie R; DeFazio, Anna A; Delnatte, Capucine C; Doheny, Kimberly F KF; Diez, Orland O; Ding, Yuan Chun YC; Doherty, Jennifer Anne JA; Domchek, Susan M SM; Dorfling, Cecilia M CM; 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Association of exome sequences with plasma C-reactive protein levels in >9000 participants.
Human Molecular Genetics
Schick, Ursula M UM; Auer, Paul L PL; Bis, Joshua C JC; Lin, Honghuang H; Wei, Peng P; Pankratz, Nathan N; Lange, Leslie A LA; Brody, Jennifer J; Stitziel, Nathan O NO; Kim, Daniel S DS; Carlson, Christopher S CS; Fornage, Myriam M; Haessler, Jeffery J; Hsu, Li L; Jackson, Rebecca D RD; Kooperberg, Charles C; Leal, Suzanne M SM; Psaty, Bruce M BM; Boerwinkle, Eric E; Tracy, Russell R; Ardissino, Diego D; Shah, Svati S; Willer, Cristen C; Loos, Ruth R; Melander, Olle O; Mcpherson, Ruth R; Hovingh, Kees K; Reilly, Muredach M; Watkins, Hugh H; Girelli, Domenico D; Fontanillas, Pierre P; Chasman, Daniel I DI; Gabriel, Stacey B SB; Gibbs, Richard R; Nickerson, Deborah A DA; Kathiresan, Sekar S; Peters, Ulrike U; Dupuis, Josée J; Wilson, James G JG; Rich, Stephen S SS; Morrison, Alanna C AC; Benjamin, Emelia J EJ; Gross, Myron D MD; Reiner, Alex P AP; , ; ,
A new susceptibility locus for myocardial infarction, hypertension, type 2 diabetes mellitus, and dyslipidemia on chromosome 12q24.
Disease Markers
Wakil, Salma M SM; Muiya, Nzioka P NP; Tahir, Asma I AI; Al-Najai, Mohammed M; Baz, Batoul B; Andres, Editha E; Mazhar, Nejat N; Al Tassan, Nada N; Alshahid, Maie M; Meyer, Brian F BF; Dzimiri, Nduna N
Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.
Plos Genetics
Lowe, Jennifer K JK; Maller, Julian B JB; Pe'er, Itsik I; Neale, Benjamin M BM; Salit, Jacqueline J; Kenny, Eimear E EE; Shea, Jessica L JL; Burkhardt, Ralph R; Smith, J Gustav JG; Ji, Weizhen W; Noel, Martha M; Foo, Jia Nee JN; Blundell, Maude L ML; Skilling, Vita V; Garcia, Laura L; Sullivan, Marcia L ML; Lee, Heather E HE; Labek, Anna A; Ferdowsian, Hope H; Auerbach, Steven B SB; Lifton, Richard P RP; Newton-Cheh, Christopher C; Breslow, Jan L JL; Stoffel, Markus M; Daly, Mark J MJ; Altshuler, David M DM; Friedman, Jeffrey M JM
Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein.
American Journal Of Human Genetics
Reiner, Alexander P AP; Barber, Mathew J MJ; Guan, Yongtao Y; Ridker, Paul M PM; Lange, Leslie A LA; Chasman, Daniel I DI; Walston, Jeremy D JD; Cooper, Gregory M GM; Jenny, Nancy S NS; Rieder, Mark J MJ; Durda, J Peter JP; Smith, Joshua D JD; Novembre, John J; Tracy, Russell P RP; Rotter, Jerome I JI; Stephens, Matthew M; Nickerson, Deborah A DA; Krauss, Ronald M RM