Association of Inherited Genetic Factors With Drug-Induced Hepatic Damage Among Children With Acute Lymphoblastic Leukemia.
Jama Network Open
Yang, Wenjian W; Karol, Seth E SE; Hoshitsuki, Keito K; Lee, Shawn S; Larsen, Eric C EC; Winick, Naomi N; Carroll, William L WL; Loh, Mignon L ML; Raetz, Elizabeth A EA; Hunger, Stephen P SP; Winter, Stuart S SS; Dunsmore, Kimberly P KP; Devidas, Meenakshi M; Relling, Mary V MV; Yang, Jun J JJ
Genetic analysis of over half a million people characterises C-reactive protein loci.
Nature Communications
Said, Saredo S; Pazoki, Raha R; Karhunen, Ville V; Võsa, Urmo U; Ligthart, Symen S; Bodinier, Barbara B; Koskeridis, Fotios F; Welsh, Paul P; Alizadeh, Behrooz Z BZ; Chasman, Daniel I DI; Sattar, Naveed N; Chadeau-Hyam, Marc M; Evangelou, Evangelos E; Jarvelin, Marjo-Riitta MR; Elliott, Paul P; Tzoulaki, Ioanna I; Dehghan, Abbas A
Enrichment analyses identify shared associations for 25 quantitative traits in over 600,000 individuals from seven diverse ancestries.
American Journal Of Human Genetics
Smith, Samuel Pattillo SP; Shahamatdar, Sahar S; Cheng, Wei W; Zhang, Selena S; Paik, Joseph J; Graff, Misa M; Haiman, Christopher C; Matise, T C TC; North, Kari E KE; Peters, Ulrike U; Kenny, Eimear E; Gignoux, Chris C; Wojcik, Genevieve G; Crawford, Lorin L; Ramachandran, Sohini S
Genetically determined elevated C-reactive protein associated with primary colorectal cancer risk: Mendelian randomization with lifestyle interactions.
American Journal Of Cancer Research
Jung, Su Yon SY; Yu, Herbert H; Pellegrini, Matteo M; Papp, Jeanette C JC; Sobel, Eric M EM; Zhang, Zuo-Feng ZF
Assessing the Relationship Between High-sensitivity C-reactive Protein and Kidney Function Employing Mendelian Randomization in the Japanese Community-based J-MICC Study.
Genome-wide association study of high-sensitivity C-reactive protein, D-dimer, and interleukin-6 levels in multiethnic HIV+ cohorts.
Aids (London, England)
Sherman, Brad T BT; Hu, Xiaojun X; Singh, Kanal K; Haine, Lillian L; Rupert, Adam W AW; Neaton, James D JD; Lundgren, Jens D JD; Imamichi, Tomozumi T; Chang, Weizhong W; Lane, H Clifford HC; ,
A pooled genome-wide association study identifies pancreatic cancer susceptibility loci on chromosome 19p12 and 19p13.3 in the full-Jewish population.
Human Genetics
Streicher, Samantha A SA; Klein, Alison P AP; Olson, Sara H SH; Kurtz, Robert C RC; Amundadottir, Laufey T LT; DeWan, Andrew T AT; Zhao, Hongyu H; Risch, Harvey A HA
Genetic Study of Hepatocyte Nuclear Factor 1 Alpha Variants in Development of Early-Onset Diabetes Type 2 and Maturity-Onset Diabetes of the Young 3 in Iran.
Advanced Biomedical Research
Mohammadi, Aliasgar A; Eskandari, Ameneh A; Sarmadi, Akram A; Rahimi, Mehrali M; Iraj, Bijan B; Hashemipour, Mahin M; Chaleshtori, Morteza Hashmezadeh MH; Tabatabaiefar, Mohammad Amin MA
Genetic analysis of hsCRP in American Indians: The Strong Heart Family Study.
Plos One
Best, Lyle G LG; Balakrishnan, Poojitha P; Cole, Shelley A SA; Haack, Karin K; Kocarnik, Jonathan M JM; Pankratz, Nathan N; Anderson, Matthew Z MZ; Franceschini, Nora N; Howard, Barbara V BV; Lee, Elisa T ET; North, Kari E KE; Umans, Jason G JG; Yracheta, Joseph M JM; Navas-Acien, Ana A; Voruganti, V Saroja VS
Genome-Wide Association Study Identifies Loci for Liver Enzyme Concentrations in Mexican Americans: The GUARDIAN Consortium.
Obesity (Silver Spring, Md.)
Young, Kendra A KA; Palmer, Nicholette D ND; Fingerlin, Tasha E TE; Langefeld, Carl D CD; Norris, Jill M JM; Wang, Nan N; Xiang, Anny H AH; Guo, Xiuqing X; Williams, Adrienne H AH; Chen, Yii-Der I YI; Taylor, Kent D KD; Rotter, Jerome I JI; Raffel, Leslie J LJ; Goodarzi, Mark O MO; Watanabe, Richard M RM; Wagenknecht, Lynne E LE
Liver Function and Risk of Type 2 Diabetes: Bidirectional Mendelian Randomization Study.
Diabetes
De Silva, N Maneka G NMG; Borges, Maria Carolina MC; Hingorani, Aroon D AD; Engmann, Jorgen J; Shah, Tina T; Zhang, Xiaoshuai X; Luan, Jian'an J; Langenberg, Claudia C; Wong, Andrew A; Kuh, Diana D; Chambers, John C JC; Zhang, Weihua W; Jarvelin, Marjo-Ritta MR; Sebert, Sylvain S; Auvinen, Juha J; , ; Gaunt, Tom R TR; Lawlor, Deborah A DA
Group IIA Secretory Phospholipase A2, Vascular Inflammation, and Incident Cardiovascular Disease.
Arteriosclerosis, Thrombosis, And Vascular Biology
Akinkuolie, Akintunde O AO; Lawler, Patrick R PR; Chu, Audrey Y AY; Caulfield, Michael M; Mu, Jianying J; Ding, Bo B; Nyberg, Fredrik F; Glynn, Robert J RJ; Ridker, Paul M PM; Hurt-Camejo, Eva E; Chasman, Daniel I DI; Mora, Samia S
Association between a Genetic Risk Score Based on Single Nucleotide Polymorphisms of Coronary Artery Disease-Related Genes and Left Main Coronary Artery Disease.
Biomed Research International
Xu, Zhengxi Z; Liu, Hanning H; Sun, Cheng C; Si, Ke K; Zhao, Yan Y; Zheng, Zhe Z
Mendelian randomization analysis of C-reactive protein on colorectal cancer risk.
International Journal Of Epidemiology
Wang, Xiaoliang X; Dai, James Y JY; Albanes, Demetrius D; Arndt, Volker V; Berndt, Sonja I SI; Bézieau, Stéphane S; Brenner, Hermann H; Buchanan, Daniel D DD; Butterbach, Katja K; Caan, Bette B; Casey, Graham G; Campbell, Peter T PT; Chan, Andrew T AT; Chen, Zhengyi Z; Chang-Claude, Jenny J; Cotterchio, Michelle M; Easton, Douglas F DF; Giles, Graham G GG; Giovannucci, Edward E; Grady, William M WM; Hoffmeister, Michael M; Hopper, John L JL; Hsu, Li L; Jenkins, Mark A MA; Joshi, Amit D AD; Lampe, Johanna W JW; Larsson, Susanna C SC; Lejbkowicz, Flavio F; Li, Li L; Lindblom, Annika A; Le Marchand, Loic L; Martin, Vicente V; Milne, Roger L RL; Moreno, Victor V; Newcomb, Polly A PA; Offitt, Kenneth K; Ogino, Shuji S; Pharoah, Paul D P PDP; Pinchev, Mila M; Potter, John D JD; Rennert, Hedy S HS; Rennert, Gad G; Saliba, Walid W; Schafmayer, Clemens C; Schoen, Robert E RE; Schrotz-King, Petra P; Slattery, Martha L ML; Song, Mingyang M; Stegmaier, Christa C; Weinstein, Stephanie J SJ; Wolk, Alicja A; Woods, Michael O MO; Wu, Anna H AH; Gruber, Stephen B SB; Peters, Ulrike U; White, Emily E
Genetic polymorphisms of diabetes-related genes, their interaction with diabetes status, and breast cancer incidence and mortality: The Long Island Breast Cancer Study Project.
Molecular Carcinogenesis
Parada, Humberto H; Cleveland, Rebecca J RJ; North, Kari E KE; Stevens, June J; Teitelbaum, Susan L SL; Neugut, Alfred I AI; Santella, Regina M RM; Martinez, Maria E ME; Gammon, Marilie D MD
Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.
American Journal Of Human Genetics
Ligthart, Symen S; Vaez, Ahmad A; Võsa, Urmo U; Stathopoulou, Maria G MG; de Vries, Paul S PS; Prins, Bram P BP; Van der Most, Peter J PJ; Tanaka, Toshiko T; Naderi, Elnaz E; Rose, Lynda M LM; Wu, Ying Y; Karlsson, Robert R; Barbalic, Maja M; Lin, Honghuang H; Pool, René R; Zhu, Gu G; Macé, Aurélien A; Sidore, Carlo C; Trompet, Stella S; Mangino, Massimo M; Sabater-Lleal, Maria M; Kemp, John P JP; Abbasi, Ali A; Kacprowski, Tim T; Verweij, Niek N; Smith, Albert V AV; Huang, Tao T; Marzi, Carola C; Feitosa, Mary F MF; Lohman, Kurt K KK; Kleber, Marcus E ME; Milaneschi, Yuri Y; Mueller, Christian C; Huq, Mahmudul M; Vlachopoulou, Efthymia E; Lyytikäinen, Leo-Pekka LP; Oldmeadow, Christopher C; Deelen, Joris J; Perola, Markus M; Zhao, Jing Hua JH; Feenstra, Bjarke B; , ; Amini, Marzyeh M; , ; Lahti, Jari J; Schraut, Katharina E KE; Fornage, Myriam M; Suktitipat, Bhoom B; Chen, Wei-Min WM; Li, Xiaohui X; Nutile, Teresa T; Malerba, Giovanni G; Luan, Jian'an J; Bak, Tom T; Schork, Nicholas N; Del Greco M, Fabiola F; Thiering, Elisabeth E; Mahajan, Anubha A; Marioni, Riccardo E RE; Mihailov, Evelin E; Eriksson, Joel J; Ozel, Ayse Bilge AB; Zhang, Weihua W; Nethander, Maria M; Cheng, Yu-Ching YC; Aslibekyan, Stella S; Ang, Wei W; Gandin, Ilaria I; Yengo, Loïc L; Portas, Laura L; Kooperberg, Charles C; Hofer, Edith E; Rajan, Kumar B KB; Schurmann, Claudia C; den Hollander, Wouter W; Ahluwalia, Tarunveer S TS; Zhao, Jing J; Draisma, Harmen H M HHM; Ford, Ian I; Timpson, Nicholas N; Teumer, Alexander A; Huang, Hongyan H; Wahl, Simone S; Liu, YongMei Y; Huang, Jie J; Uh, Hae-Won HW; Geller, Frank F; Joshi, Peter K PK; Yanek, Lisa R LR; Trabetti, Elisabetta E; Lehne, Benjamin B; Vozzi, Diego D; Verbanck, Marie M; Biino, Ginevra G; Saba, Yasaman Y; Meulenbelt, Ingrid I; O'Connell, Jeff R JR; Laakso, Markku M; Giulianini, Franco F; Magnusson, Patrik K E PKE; Ballantyne, Christie M CM; Hottenga, Jouke Jan JJ; Montgomery, Grant W GW; Rivadineira, Fernando F; Rueedi, Rico R; Steri, Maristella M; Herzig, Karl-Heinz KH; Stott, David J DJ; Menni, Cristina C; Frånberg, Mattias M; St Pourcain, Beate B; Felix, Stephan B SB; Pers, Tune H TH; Bakker, Stephan J L SJL; Kraft, Peter P; Peters, Annette A; Vaidya, Dhananjay D; Delgado, Graciela G; Smit, Johannes H JH; Großmann, Vera V; Sinisalo, Juha J; Seppälä, Ilkka I; Williams, Stephen R SR; Holliday, Elizabeth G EG; Moed, Matthijs M; Langenberg, Claudia C; Räikkönen, Katri K; Ding, Jingzhong J; Campbell, Harry H; Sale, Michele M MM; Chen, Yii-Der I YI; James, Alan L AL; Ruggiero, Daniela D; Soranzo, Nicole N; Hartman, Catharina A CA; Smith, Erin N EN; Berenson, Gerald S GS; Fuchsberger, Christian C; Hernandez, Dena D; Tiesler, Carla M T CMT; Giedraitis, Vilmantas V; Liewald, David D; Fischer, Krista K; Mellström, Dan D; Larsson, Anders A; Wang, Yunmei Y; Scott, William R WR; Lorentzon, Matthias M; Beilby, John J; Ryan, Kathleen A KA; Pennell, Craig E CE; Vuckovic, Dragana D; Balkau, Beverly B; Concas, Maria Pina MP; Schmidt, Reinhold R; Mendes de Leon, Carlos F CF; Bottinger, Erwin P EP; Kloppenburg, Margreet M; Paternoster, Lavinia L; Boehnke, Michael M; Musk, A W AW; Willemsen, Gonneke G; Evans, David M DM; Madden, Pamela A F PAF; Kähönen, Mika M; Kutalik, Zoltán Z; Zoledziewska, Magdalena M; Karhunen, Ville V; Kritchevsky, Stephen B SB; Sattar, Naveed N; Lachance, Genevieve G; Clarke, Robert R; Harris, Tamara B TB; Raitakari, Olli T OT; Attia, John R JR; van Heemst, Diana D; Kajantie, Eero E; Sorice, Rossella R; Gambaro, Giovanni G; Scott, Robert A RA; Hicks, Andrew A AA; Ferrucci, Luigi L; Standl, Marie M; Lindgren, Cecilia M CM; Starr, John M JM; Karlsson, Magnus M; Lind, Lars L; Li, Jun Z JZ; Chambers, John C JC; Mori, Trevor A TA; de Geus, Eco J C N EJCN; Heath, Andrew C AC; Martin, Nicholas G NG; Auvinen, Juha J; Buckley, Brendan M BM; de Craen, Anton J M AJM; Waldenberger, Melanie M; Strauch, Konstantin K; Meitinger, Thomas T; Scott, Rodney J RJ; McEvoy, Mark M; Beekman, Marian M; Bombieri, Cristina C; Ridker, Paul M PM; Mohlke, Karen L KL; Pedersen, Nancy L NL; Morrison, Alanna C AC; Boomsma, Dorret I DI; Whitfield, John B JB; Strachan, David P DP; Hofman, Albert A; Vollenweider, Peter P; Cucca, Francesco F; Jarvelin, Marjo-Riitta MR; Jukema, J Wouter JW; Spector, Tim D TD; Hamsten, Anders A; Zeller, Tanja T; Uitterlinden, André G AG; Nauck, Matthias M; Gudnason, Vilmundur V; Qi, Lu L; Grallert, Harald H; Borecki, Ingrid B IB; Rotter, Jerome I JI; März, Winfried W; Wild, Philipp S PS; Lokki, Marja-Liisa ML; Boyle, Michael M; Salomaa, Veikko V; Melbye, Mads M; Eriksson, Johan G JG; Wilson, James F JF; Penninx, Brenda W J H BWJH; Becker, Diane M DM; Worrall, Bradford B BB; Gibson, Greg G; Krauss, Ronald M RM; Ciullo, Marina M; Zaza, Gianluigi G; Wareham, Nicholas J NJ; Oldehinkel, Albertine J AJ; Palmer, Lyle J LJ; Murray, Sarah S SS; Pramstaller, Peter P PP; Bandinelli, Stefania S; Heinrich, Joachim J; Ingelsson, Erik E; Deary, Ian J IJ; Mägi, Reedik R; Vandenput, Liesbeth L; van der Harst, Pim P; Desch, Karl C KC; Kooner, Jaspal S JS; Ohlsson, Claes C; Hayward, Caroline C; Lehtimäki, Terho T; Shuldiner, Alan R AR; Arnett, Donna K DK; Beilin, Lawrence J LJ; Robino, Antonietta A; Froguel, Philippe P; Pirastu, Mario M; Jess, Tine T; Koenig, Wolfgang W; Loos, Ruth J F RJF; Evans, Denis A DA; Schmidt, Helena H; Smith, George Davey GD; Slagboom, P Eline PE; Eiriksdottir, Gudny G; Morris, Andrew P AP; Psaty, Bruce M BM; Tracy, Russell P RP; Nolte, Ilja M IM; Boerwinkle, Eric E; Visvikis-Siest, Sophie S; Reiner, Alex P AP; Gross, Myron M; Bis, Joshua C JC; Franke, Lude L; Franco, Oscar H OH; Benjamin, Emelia J EJ; Chasman, Daniel I DI; Dupuis, Josée J; Snieder, Harold H; Dehghan, Abbas A; Alizadeh, Behrooz Z BZ
HNF1A is a novel oncogene that regulates human pancreatic cancer stem cell properties.
Elife
Abel, Ethan V EV; Goto, Masashi M; Magnuson, Brian B; Abraham, Saji S; Ramanathan, Nikita N; Hotaling, Emily E; Alaniz, Anthony A AA; Kumar-Sinha, Chandan C; Dziubinski, Michele L ML; Urs, Sumithra S; Wang, Lidong L; Shi, Jiaqi J; Waghray, Meghna M; Ljungman, Mats M; Crawford, Howard C HC; Simeone, Diane M DM
Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer.
Nature Communications
Klein, Alison P AP; Wolpin, Brian M BM; Risch, Harvey A HA; Stolzenberg-Solomon, Rachael Z RZ; Mocci, Evelina E; Zhang, Mingfeng M; Canzian, Federico F; Childs, Erica J EJ; Hoskins, Jason W JW; Jermusyk, Ashley A; Zhong, Jun J; Chen, Fei F; Albanes, Demetrius D; Andreotti, Gabriella G; Arslan, Alan A AA; Babic, Ana A; Bamlet, William R WR; Beane-Freeman, Laura L; Berndt, Sonja I SI; Blackford, Amanda A; Borges, Michael M; Borgida, Ayelet A; Bracci, Paige M PM; Brais, Lauren L; Brennan, Paul P; Brenner, Hermann H; Bueno-de-Mesquita, Bas B; Buring, Julie J; Campa, Daniele D; Capurso, Gabriele G; Cavestro, Giulia Martina GM; Chaffee, Kari G KG; Chung, Charles C CC; Cleary, Sean S; Cotterchio, Michelle M; Dijk, Frederike F; Duell, Eric J EJ; Foretova, Lenka L; Fuchs, Charles C; Funel, Niccola N; Gallinger, Steven S; M Gaziano, J Michael JM; Gazouli, Maria M; Giles, Graham G GG; Giovannucci, Edward E; Goggins, Michael M; Goodman, Gary E GE; Goodman, Phyllis J PJ; Hackert, Thilo T; Haiman, Christopher C; Hartge, Patricia P; Hasan, Manal M; Hegyi, Peter P; Helzlsouer, Kathy J KJ; Herman, Joseph J; Holcatova, Ivana I; Holly, Elizabeth A EA; Hoover, Robert R; Hung, Rayjean J RJ; Jacobs, Eric J EJ; Jamroziak, Krzysztof K; Janout, Vladimir V; Kaaks, Rudolf R; Khaw, Kay-Tee KT; Klein, Eric A EA; Kogevinas, Manolis M; Kooperberg, Charles C; Kulke, Matthew H MH; Kupcinskas, Juozas J; Kurtz, Robert J RJ; Laheru, Daniel D; Landi, Stefano S; Lawlor, Rita T RT; Lee, I-Min IM; LeMarchand, Loic L; Lu, Lingeng L; Malats, Núria N; Mambrini, Andrea A; Mannisto, Satu S; Milne, Roger L RL; Mohelníková-Duchoňová, Beatrice B; Neale, Rachel E RE; Neoptolemos, John P JP; Oberg, Ann L AL; Olson, Sara H SH; Orlow, Irene I; Pasquali, Claudio C; Patel, Alpa V AV; Peters, Ulrike U; Pezzilli, Raffaele R; Porta, Miquel M; Real, Francisco X FX; Rothman, Nathaniel N; Scelo, Ghislaine G; Sesso, Howard D HD; Severi, Gianluca G; Shu, Xiao-Ou XO; Silverman, Debra D; Smith, Jill P JP; Soucek, Pavel P; Sund, Malin M; Talar-Wojnarowska, Renata R; Tavano, Francesca F; Thornquist, Mark D MD; Tobias, Geoffrey S GS; Van Den Eeden, Stephen K SK; Vashist, Yogesh Y; Visvanathan, Kala K; Vodicka, Pavel P; Wactawski-Wende, Jean J; Wang, Zhaoming Z; Wentzensen, Nicolas N; White, Emily E; Yu, Herbert H; Yu, Kai K; Zeleniuch-Jacquotte, Anne A; Zheng, Wei W; Kraft, Peter P; Li, Donghui D; Chanock, Stephen S; Obazee, Ofure O; Petersen, Gloria M GM; Amundadottir, Laufey T LT
Hepatocyte nuclear factors as possible C-reactive protein transcriptional inducer in the liver and white adipose tissue of rats with experimental chronic renal failure.
Molecular And Cellular Biochemistry
Sucajtys-Szulc, Elzbieta E; Debska-Slizien, Alicja A; Rutkowski, Boleslaw B; Milczarek, Ryszard R; Pelikant-Malecka, Iwona I; Sledzinski, Tomasz T; Swierczynski, Julian J; Szolkiewicz, Marek M
Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.
Nature Genetics
Phelan, Catherine M CM; Kuchenbaecker, Karoline B KB; Tyrer, Jonathan P JP; Kar, Siddhartha P SP; Lawrenson, Kate K; Winham, Stacey J SJ; Dennis, Joe J; Pirie, Ailith A; Riggan, Marjorie J MJ; Chornokur, Ganna G; Earp, Madalene A MA; Lyra, Paulo C PC; Lee, Janet M JM; Coetzee, Simon S; Beesley, Jonathan J; McGuffog, Lesley L; Soucy, Penny P; Dicks, Ed E; Lee, Andrew A; Barrowdale, Daniel D; Lecarpentier, Julie J; Leslie, Goska G; Aalfs, Cora M CM; Aben, Katja K H KKH; Adams, Marcia M; Adlard, Julian J; Andrulis, Irene L IL; Anton-Culver, Hoda H; Antonenkova, Natalia N; , ; Aravantinos, Gerasimos G; Arnold, Norbert N; Arun, Banu K BK; Arver, Brita B; Azzollini, Jacopo J; Balmaña, Judith J; Banerjee, Susana N SN; Barjhoux, Laure L; Barkardottir, Rosa B RB; Bean, Yukie Y; Beckmann, Matthias W MW; Beeghly-Fadiel, Alicia A; Benitez, Javier J; Bermisheva, Marina M; Bernardini, Marcus Q MQ; Birrer, Michael J MJ; Bjorge, Line L; Black, Amanda A; Blankstein, Kenneth K; Blok, Marinus J MJ; Bodelon, Clara C; 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Pancreatic cancer-associated gene polymorphisms in a nation-wide cohort of p16-Leiden germline mutation carriers; a case-control study.
Bmc Research Notes
Potjer, Thomas P TP; van der Stoep, Nienke N; Houwing-Duistermaat, Jeanine J JJ; Konings, Ingrid C A W IC; Aalfs, Cora M CM; van den Akker, Peter C PC; Ausems, Margreet G MG; Dommering, Charlotte J CJ; van der Kolk, Lizet E LE; Maiburg, Merel C MC; Spruijt, Liesbeth L; Wagner, Anja A; Vasen, Hans F A HF; Hes, Frederik J FJ
Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer.
Nature Genetics
Childs, Erica J EJ; Mocci, Evelina E; Campa, Daniele D; Bracci, Paige M PM; Gallinger, Steven S; Goggins, Michael M; Li, Donghui D; Neale, Rachel E RE; Olson, Sara H SH; Scelo, Ghislaine G; Amundadottir, Laufey T LT; Bamlet, William R WR; Bijlsma, Maarten F MF; Blackford, Amanda A; Borges, Michael M; Brennan, Paul P; Brenner, Hermann H; Bueno-de-Mesquita, H Bas HB; Canzian, Federico F; Capurso, Gabriele G; Cavestro, Giulia M GM; Chaffee, Kari G KG; Chanock, Stephen J SJ; Cleary, Sean P SP; Cotterchio, Michelle M; Foretova, Lenka L; Fuchs, Charles C; Funel, Niccola N; Gazouli, Maria M; Hassan, Manal M; Herman, Joseph M JM; Holcatova, Ivana I; Holly, Elizabeth A EA; Hoover, Robert N RN; Hung, Rayjean J RJ; Janout, Vladimir V; Key, Timothy J TJ; Kupcinskas, Juozas J; Kurtz, Robert C RC; Landi, Stefano S; Lu, Lingeng L; Malecka-Panas, Ewa E; Mambrini, Andrea A; Mohelnikova-Duchonova, Beatrice B; Neoptolemos, John P JP; Oberg, Ann L AL; Orlow, Irene I; Pasquali, Claudio C; Pezzilli, Raffaele R; Rizzato, Cosmeri C; Saldia, Amethyst A; Scarpa, Aldo A; Stolzenberg-Solomon, Rachael Z RZ; Strobel, Oliver O; Tavano, Francesca F; Vashist, Yogesh K YK; Vodicka, Pavel P; Wolpin, Brian M BM; Yu, Herbert H; Petersen, Gloria M GM; Risch, Harvey A HA; Klein, Alison P AP
A new susceptibility locus for myocardial infarction, hypertension, type 2 diabetes mellitus, and dyslipidemia on chromosome 12q24.
Disease Markers
Wakil, Salma M SM; Muiya, Nzioka P NP; Tahir, Asma I AI; Al-Najai, Mohammed M; Baz, Batoul B; Andres, Editha E; Mazhar, Nejat N; Al Tassan, Nada N; Alshahid, Maie M; Meyer, Brian F BF; Dzimiri, Nduna N
Multiancestral analysis of inflammation-related genetic variants and C-reactive protein in the population architecture using genomics and epidemiology study.
Circulation. Cardiovascular Genetics
Kocarnik, Jonathan M JM; Pendergrass, Sarah A SA; Carty, Cara L CL; Pankow, James S JS; Schumacher, Fredrick R FR; Cheng, Iona I; Durda, Peter P; Ambite, José Luis JL; Deelman, Ewa E; Cook, Nancy R NR; Liu, Simin S; Wactawski-Wende, Jean J; Hutter, Carolyn C; Brown-Gentry, Kristin K; Wilson, Sarah S; Best, Lyle G LG; Pankratz, Nathan N; Hong, Ching-Ping CP; Cole, Shelley A SA; Voruganti, V Saroja VS; Bůžkova, Petra P; Jorgensen, Neal W NW; Jenny, Nancy S NS; Wilkens, Lynne R LR; Haiman, Christopher A CA; Kolonel, Laurence N LN; Lacroix, Andrea A; North, Kari K; Jackson, Rebecca R; Le Marchand, Loic L; Hindorff, Lucia A LA; Crawford, Dana C DC; Gross, Myron M; Peters, Ulrike U
Hepatocyte nuclear factor 1 regulates the expression of the organic cation transporter 1 via binding to an evolutionary conserved region in intron 1 of the OCT1 gene.
The Journal Of Pharmacology And Experimental Therapeutics
O'Brien, Valerie P VP; Bokelmann, Kristin K; Ramírez, Jacqueline J; Jobst, Karoline K; Ratain, Mark J MJ; Brockmöller, Jürgen J; Tzvetkov, Mladen V MV
Are C-reactive protein associated genetic variants associated with serum levels and retinal markers of microvascular pathology in Asian populations from Singapore?
Plos One
Dorajoo, Rajkumar R; Li, Ruoying R; Ikram, Mohammad Kamran MK; Liu, Jianjun J; Froguel, Philippe P; Lee, Jeannette J; Sim, Xueling X; Ong, Rick Twee-Hee RT; Tay, Wan Ting WT; Peng, Chen C; Young, Terri L TL; Blakemore, Alexandra I F AI; Cheng, Ching Yu CY; Aung, Tin T; Mitchell, Paul P; Wang, Jie Jin JJ; Klaver, Caroline C CC; Boerwinkle, Eric E; Klein, Ronald R; Siscovick, David S DS; Jensen, Richard A RA; Gudnason, Vilmundur V; Smith, Albert Vernon AV; Teo, Yik Ying YY; Wong, Tien Yin TY; Tai, E-Shyong ES; Heng, Chew-Kiat CK; Friedlander, Yechiel Y
SHAVE: shrinkage estimator measured for multiple visits increases power in GWAS of quantitative traits.
European Journal Of Human Genetics : Ejhg
Meirelles, Osorio D OD; Ding, Jun J; Tanaka, Toshiko T; Sanna, Serena S; Yang, Hsih-Te HT; Dudekula, Dawood B DB; Cucca, Francesco F; Ferrucci, Luigi L; Abecasis, Goncalo G; Schlessinger, David D
Pathway analysis of genome-wide association study data highlights pancreatic development genes as susceptibility factors for pancreatic cancer.
Carcinogenesis
Li, Donghui D; Duell, Eric J EJ; Yu, Kai K; Risch, Harvey A HA; Olson, Sara H SH; Kooperberg, Charles C; Wolpin, Brian M BM; Jiao, Li L; Dong, Xiaoqun X; Wheeler, Bill B; Arslan, Alan A AA; Bueno-de-Mesquita, H Bas HB; Fuchs, Charles S CS; Gallinger, Steven S; Gross, Myron M; Hartge, Patricia P; Hoover, Robert N RN; Holly, Elizabeth A EA; Jacobs, Eric J EJ; Klein, Alison P AP; LaCroix, Andrea A; Mandelson, Margaret T MT; Petersen, Gloria G; Zheng, Wei W; Agalliu, Ilir I; Albanes, Demetrius D; Boutron-Ruault, Marie-Christine MC; Bracci, Paige M PM; Buring, Julie E JE; Canzian, Federico F; Chang, Kenneth K; Chanock, Stephen J SJ; Cotterchio, Michelle M; Gaziano, J Michael JM; Giovannucci, Edward L EL; Goggins, Michael M; Hallmans, Göran G; Hankinson, Susan E SE; Hoffman Bolton, Judith A JA; Hunter, David J DJ; Hutchinson, Amy A; Jacobs, Kevin B KB; Jenab, Mazda M; Khaw, Kay-Tee KT; Kraft, Peter P; Krogh, Vittorio V; Kurtz, Robert C RC; McWilliams, Robert R RR; Mendelsohn, Julie B JB; Patel, Alpa V AV; Rabe, Kari G KG; Riboli, Elio E; Shu, Xiao-Ou XO; Tjønneland, Anne A; Tobias, Geoffrey S GS; Trichopoulos, Dimitrios D; Virtamo, Jarmo J; Visvanathan, Kala K; Watters, Joanne J; Yu, Herbert H; Zeleniuch-Jacquotte, Anne A; Amundadottir, Laufey L; Stolzenberg-Solomon, Rachael Z RZ
C-reactive protein (CRP) promoter polymorphisms influence circulating CRP levels in a genome-wide association study of African Americans.
Human Molecular Genetics
Doumatey, Ayo P AP; Chen, Guanjie G; Tekola Ayele, Fasil F; Zhou, Jie J; Erdos, Michael M; Shriner, Daniel D; Huang, Hanxia H; Adeleye, Jokotade J; Balogun, Williams W; Fasanmade, Olufemi O; Johnson, Thomas T; Oli, Johnnie J; Okafor, Godfrey G; Amoah, Albert A; Eghan, Benjamin A BA; Agyenim-Boateng, Kofi K; Acheampong, Joseph J; Adebamowo, Clement C; Gerry, Norman P NP; Christman, Michael F MF; Adeyemo, Adebowale A; Rotimi, Charles N CN
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.
Nature Genetics
Chambers, John C JC; Zhang, Weihua W; Sehmi, Joban J; Li, Xinzhong X; Wass, Mark N MN; Van der Harst, Pim P; Holm, Hilma H; Sanna, Serena S; Kavousi, Maryam M; Baumeister, Sebastian E SE; Coin, Lachlan J LJ; Deng, Guohong G; Gieger, Christian C; Heard-Costa, Nancy L NL; Hottenga, Jouke-Jan JJ; Kühnel, Brigitte B; Kumar, Vinod V; Lagou, Vasiliki V; Liang, Liming L; Luan, Jian'an J; Vidal, Pedro Marques PM; Mateo Leach, Irene I; O'Reilly, Paul F PF; Peden, John F JF; Rahmioglu, Nilufer N; Soininen, Pasi P; Speliotes, Elizabeth K EK; Yuan, Xin X; Thorleifsson, Gudmar G; Alizadeh, Behrooz Z BZ; Atwood, Larry D LD; Borecki, Ingrid B IB; Brown, Morris J MJ; Charoen, Pimphen P; Cucca, Francesco F; Das, Debashish D; de Geus, Eco J C EJ; Dixon, Anna L AL; Döring, Angela A; Ehret, Georg G; Eyjolfsson, Gudmundur I GI; Farrall, Martin M; Forouhi, Nita G NG; Friedrich, Nele N; Goessling, Wolfram W; Gudbjartsson, Daniel F DF; Harris, Tamara B TB; Hartikainen, Anna-Liisa AL; Heath, Simon S; Hirschfield, Gideon M GM; Hofman, Albert A; Homuth, Georg G; Hyppönen, Elina E; Janssen, Harry L A HL; Johnson, Toby T; Kangas, Antti J AJ; Kema, Ido P IP; Kühn, Jens P JP; Lai, Sandra S; Lathrop, Mark M; Lerch, Markus M MM; Li, Yun Y; Liang, T Jake TJ; Lin, Jing-Ping JP; Loos, Ruth J F RJ; Martin, Nicholas G NG; Moffatt, Miriam F MF; Montgomery, Grant W GW; Munroe, Patricia B PB; Musunuru, Kiran K; Nakamura, Yusuke Y; O'Donnell, Christopher J CJ; Olafsson, Isleifur I; Penninx, Brenda W BW; Pouta, Anneli A; Prins, Bram P BP; Prokopenko, Inga I; Puls, Ralf R; Ruokonen, Aimo A; Savolainen, Markku J MJ; Schlessinger, David D; Schouten, Jeoffrey N L JN; Seedorf, Udo U; Sen-Chowdhry, Srijita S; Siminovitch, Katherine A KA; Smit, Johannes H JH; Spector, Timothy D TD; Tan, Wenting W; Teslovich, Tanya M TM; Tukiainen, Taru T; Uitterlinden, Andre G AG; Van der Klauw, Melanie M MM; Vasan, Ramachandran S RS; Wallace, Chris C; Wallaschofski, Henri H; Wichmann, H-Erich HE; Willemsen, Gonneke G; Würtz, Peter P; Xu, Chun C; Yerges-Armstrong, Laura M LM; , ; , ; , ; , ; , ; , ; , ; Abecasis, Goncalo R GR; Ahmadi, Kourosh R KR; Boomsma, Dorret I DI; Caulfield, Mark M; Cookson, William O WO; van Duijn, Cornelia M CM; Froguel, Philippe P; Matsuda, Koichi K; McCarthy, Mark I MI; Meisinger, Christa C; Mooser, Vincent V; Pietiläinen, Kirsi H KH; Schumann, Gunter G; Snieder, Harold H; Sternberg, Michael J E MJ; Stolk, Ronald P RP; Thomas, Howard C HC; Thorsteinsdottir, Unnur U; Uda, Manuela M; Waeber, Gérard G; Wareham, Nicholas J NJ; Waterworth, Dawn M DM; Watkins, Hugh H; Whitfield, John B JB; Witteman, Jacqueline C M JC; Wolffenbuttel, Bruce H R BH; Fox, Caroline S CS; Ala-Korpela, Mika M; Stefansson, Kari K; Vollenweider, Peter P; Völzke, Henry H; Schadt, Eric E EE; Scott, James J; Järvelin, Marjo-Riitta MR; Elliott, Paul P; Kooner, Jaspal S JS
Single-nucleotide polymorphisms at five loci are associated with C-reactive protein levels in a cohort of Filipino young adults.
Journal Of Human Genetics
Curocichin, Ghenadie G; Wu, Ying Y; McDade, Thomas W TW; Kuzawa, Christopher W CW; Borja, Judith B JB; Qin, Li L; Lange, Ethan M EM; Adair, Linda S LS; Lange, Leslie A LA; Mohlke, Karen L KL
Genome-wide association with C-reactive protein levels in CLHNS: evidence for the CRP and HNF1A loci and their interaction with exposure to a pathogenic environment.
Inflammation
Wu, Ying Y; McDade, Thomas W TW; Kuzawa, Christopher W CW; Borja, Judith J; Li, Yun Y; Adair, Linda S LS; Mohlke, Karen L KL; Lange, Leslie A LA
Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a genome-wide association study of fibrinogen in 17 686 women: the Women's Genome Health Study.
Circulation. Cardiovascular Genetics
Danik, Jacqueline S JS; Paré, Guillaume G; Chasman, Daniel I DI; Zee, Robert Y L RY; Kwiatkowski, David J DJ; Parker, Alex A; Miletich, Joseph P JP; Ridker, Paul M PM
Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.
Plos Genetics
Lowe, Jennifer K JK; Maller, Julian B JB; Pe'er, Itsik I; Neale, Benjamin M BM; Salit, Jacqueline J; Kenny, Eimear E EE; Shea, Jessica L JL; Burkhardt, Ralph R; Smith, J Gustav JG; Ji, Weizhen W; Noel, Martha M; Foo, Jia Nee JN; Blundell, Maude L ML; Skilling, Vita V; Garcia, Laura L; Sullivan, Marcia L ML; Lee, Heather E HE; Labek, Anna A; Ferdowsian, Hope H; Auerbach, Steven B SB; Lifton, Richard P RP; Newton-Cheh, Christopher C; Breslow, Jan L JL; Stoffel, Markus M; Daly, Mark J MJ; Altshuler, David M DM; Friedman, Jeffrey M JM
Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein.
American Journal Of Human Genetics
Reiner, Alexander P AP; Barber, Mathew J MJ; Guan, Yongtao Y; Ridker, Paul M PM; Lange, Leslie A LA; Chasman, Daniel I DI; Walston, Jeremy D JD; Cooper, Gregory M GM; Jenny, Nancy S NS; Rieder, Mark J MJ; Durda, J Peter JP; Smith, Joshua D JD; Novembre, John J; Tracy, Russell P RP; Rotter, Jerome I JI; Stephens, Matthew M; Nickerson, Deborah A DA; Krauss, Ronald M RM
Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study.
American Journal Of Human Genetics
Ridker, Paul M PM; Pare, Guillaume G; Parker, Alex A; Zee, Robert Y L RY; Danik, Jacqueline S JS; Buring, Julie E JE; Kwiatkowski, David D; Cook, Nancy R NR; Miletich, Joseph P JP; Chasman, Daniel I DI