LRP6 c.4321C>G ;(p.R1441G)

Variant ID: 12-12278358-G-C

NM_002336.2(LRP6):c.4321C>G;(p.R1441G)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


Microglia Polarization, Gene-Environment Interactions and Wnt/β-Catenin Signaling: Emerging Roles of Glia-Neuron and Glia-Stem/Neuroprogenitor Crosstalk for Dopaminergic Neurorestoration in Aged Parkinsonian Brain.

Frontiers In Aging Neuroscience
L'Episcopo, Francesca F; Tirolo, Cataldo C; Serapide, Maria F MF; Caniglia, Salvatore S; Testa, Nunzio N; Leggio, Loredana L; Vivarelli, Silvia S; Iraci, Nunzio N; Pluchino, Stefano S; Marchetti, Bianca B
Publication Date: 2018

Variant appearance in text: LRP6: R1441G
PubMed Link: 29483868
Variant Present in the following documents:
  • fnagi-10-00012.pdf
View BVdb publication page



The regulation and deregulation of Wnt signaling by PARK genes in health and disease.

Journal Of Molecular Cell Biology
Berwick, Daniel C DC; Harvey, Kirsten K
Publication Date: 2014-02

Variant appearance in text: LRP6: R1441G
PubMed Link: 24115276
Variant Present in the following documents:
  • Main text
View BVdb publication page



LRRK2 functions as a Wnt signaling scaffold, bridging cytosolic proteins and membrane-localized LRP6.

Human Molecular Genetics
Berwick, Daniel C DC; Harvey, Kirsten K
Publication Date: 2012-11-15

Variant appearance in text: LRP6: R1441G
PubMed Link: 22899650
Variant Present in the following documents:
  • Main text
  • dds342.pdf
View BVdb publication page