Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling.
Elife
Tsutsumi, Naotaka N; Mukherjee, Somnath S; Waghray, Deepa D; Janda, Claudia Y CY; Jude, Kevin M KM; Miao, Yi Y; Burg, John S JS; Aduri, Nanda Gowtham NG; Kossiakoff, Anthony A AA; Gati, Cornelius C; Garcia, K Christopher KC