LRP6 c.34A>T ;(p.S12C)

Variant ID: 12-12419636-T-A

NM_002336.2(LRP6):c.34A>T;(p.S12C)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


Inhibition of Dopamine Receptor D1 Signaling Promotes Human Bile Duct Cancer Progression via WNT signaling.

Cancer Science
Yogo, Akitada A; Masui, Toshihiko T; Takaishi, Shigeo S; Masuo, Kenji K; Chen, Ru R; Kasai, Yosuke Y; Nagai, Kazuyuki K; Anazawa, Takayuki T; Watanabe, Sadanori S; Sakamoto, Satoko S; Watanabe, Akira A; Inagaki, Ryosaku R; Nakagawa, Masahiro M MM; Ogawa, Seishi S; Seno, Hiroshi H; Uemoto, Shinji S; Hatano, Etsuro E
Publication Date: 2022-11-28

Variant appearance in text: LRP6: S12C
PubMed Link: 36441110
Variant Present in the following documents:
  • Main text
  • CAS-114-1324.pdf
View BVdb publication page



Cardiomyocyte-Restricted Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) Deletion Leads to Lethal Dilated Cardiomyopathy Partly Through Drp1 Signaling.

Theranostics
Chen, Zhidan Z; Li, Yang Y; Wang, Ying Y; Qian, Juying J; Ma, Hong H; Wang, Xiang X; Jiang, Guoliang G; Liu, Ming M; An, Yanpeng Y; Ma, Leilei L; Kang, Le L; Jia, Jianguo J; Yang, Chunjie C; Zhang, Guoping G; Chen, Ying Y; Gao, Wei W; Fu, Mingqiang M; Huang, Zheyong Z; Tang, Huiru H; Zhu, Yichun Y; Ge, Junbo J; Gong, Hui H; Zou, Yunzeng Y
Publication Date: 2018

Variant appearance in text: LRP6: S12C
PubMed Link: 29344294
Variant Present in the following documents:
  • thnov08p0627.pdf
View BVdb publication page



Regulation of Stem Cell Proliferation and Cell Fate Specification by Wingless/Wnt Signaling Gradients Enriched at Adult Intestinal Compartment Boundaries.

Plos Genetics
Tian, Ai A; Benchabane, Hassina H; Wang, Zhenghan Z; Ahmed, Yashi Y
Publication Date: 2016-02

Variant appearance in text: LRP6: S12C
PubMed Link: 26845150
Variant Present in the following documents:
  • Main text
  • pgen.1005822.pdf
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WNT7B promotes bone formation in part through mTORC1.

Plos Genetics
Chen, Jianquan J; Tu, Xiaolin X; Esen, Emel E; Joeng, Kyu Sang KS; Lin, Congxin C; Arbeit, Jeffrey M JM; Rüegg, Markus A MA; Hall, Michael N MN; Ma, Liang L; Long, Fanxin F
Publication Date: 2014-01

Variant appearance in text: LRP6: S12C
PubMed Link: 24497849
Variant Present in the following documents:
  • Main text
  • pgen.1004145.pdf
View BVdb publication page



NLK positively regulates Wnt/β-catenin signalling by phosphorylating LEF1 in neural progenitor cells.

The Embo Journal
Ota, Satoshi S; Ishitani, Shizuka S; Shimizu, Nobuyuki N; Matsumoto, Kunihiro K; Itoh, Motoyuki M; Ishitani, Tohru T
Publication Date: 2012-04-18

Variant appearance in text: LRP6: S12C
PubMed Link: 22373574
Variant Present in the following documents:
  • Main text
View BVdb publication page



Dishevelled, a Wnt signalling component, is involved in mitotic progression in cooperation with Plk1.

The Embo Journal
Kikuchi, Koji K; Niikura, Yohei Y; Kitagawa, Katsumi K; Kikuchi, Akira A
Publication Date: 2010-10-20

Variant appearance in text: LRP6: S12C
PubMed Link: 20823832
Variant Present in the following documents:
  • Main text
View BVdb publication page