POLE c.4933C>T ;(p.Q1645*)

Variant ID: 12-133219111-G-A

NM_006231.2(POLE):c.4933C>T;(p.Q1645*)

This variant was identified in 2 publications

View GRCh38 version.




Publications:


Characterization of leukemic resistance to CD19-targeted CAR T-cell therapy through deep genomic sequencing.

Cancer Immunology Research
Chen, Gregory M GM; Chen, Chia-Hui CH; Perazzelli, Jessica J; Grupp, Stephan A SA; Barrett, David M DM; Tan, Kai K
Publication Date: 2022-10-18

Variant appearance in text: POLE: Q1645X
PubMed Link: 36255409
Variant Present in the following documents:
  • cir-22-0095_supplementary_table_2_suppst2.xlsx, sheet 2
View BVdb publication page



Combined mismatch repair and POLE/POLD1 defects explain unresolved suspected Lynch syndrome cancers.

European Journal Of Human Genetics : Ejhg
Jansen, Anne Ml AM; van Wezel, Tom T; van den Akker, Brendy Ewm BE; Ventayol Garcia, Marina M; Ruano, Dina D; Tops, Carli Mj CM; Wagner, Anja A; Letteboer, Tom Gw TG; Gómez-García, Encarna B EB; Devilee, Peter P; Wijnen, Juul T JT; Hes, Frederik J FJ; Morreau, Hans H
Publication Date: 2016-07

Variant appearance in text: POLE: 4933C>T
PubMed Link: 26648449
Variant Present in the following documents:
  • ejhg2015252x4.xlsx, sheet 1
View BVdb publication page