Publications:

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Distinct molecular phenotype and the potential prognostic value of immune prognostic index and tumor infiltrating lymphocytes in hepatoid adenocarcinoma of stomach.

Translational Oncology

Kang, Muxing M; Ma, Xiaojing X; Shi, Jifei J; Chen, Guofeng G; Jin, Xiaoli X; Wang, Jun J; Lin, Lele L; Wu, Zhiwei Z; Chen, Kaibo K; Xu, Jinghong J; Huang, Pintong P; Chen, Jian J

Publication Date: 2022-05

Variant appearance in text: POLE: P436H

PubMed Link: 35276435

Variant Present in the following documents:

• Main text
• main.pdf

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POLE/POLD1 mutation in non-exonuclease domain matters for predicting efficacy of immune-checkpoint-inhibitor therapy.

Clinical And Translational Medicine

Chen, Yan-Xing YX; Wang, Zi-Xian ZX; Yuan, Shu-Qiang SQ; Jiang, Teng-Jia TJ; Huang, You-Sheng YS; Xu, Rui-Hua RH; Wang, Feng F; Zhao, Qi Q

Publication Date: 2021-09

Variant appearance in text: POLE: P436H

PubMed Link: 34586735

Variant Present in the following documents:

• CTM2-11-e524-s001.xlsx, sheet 2

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A computational and structural analysis of germline and somatic variants affecting the DDR mechanism, and their impact on human diseases.

Scientific Reports

Magraner-Pardo, Lorena L; Laskowski, Roman A RA; Pons, Tirso T; Thornton, Janet M JM

Publication Date: 2021-07-12

Variant appearance in text: POLE: 1307C>A; P436H

PubMed Link: 34253785

Variant Present in the following documents:

• 41598_2021_93715_MOESM2_ESM.xlsx, sheet 10

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Modeling biological and genetic diversity in upper tract urothelial carcinoma with patient derived xenografts.

Nature Communications

Kim, Kwanghee K; Hu, Wenhuo W; Audenet, François F; Almassi, Nima N; Hanrahan, Aphrothiti J AJ; Murray, Katie K; Bagrodia, Aditya A; Wong, Nathan N; Clinton, Timothy N TN; Dason, Shawn S; Mohan, Vishnu V; Jebiwott, Sylvia S; Nagar, Karan K; Gao, Jianjiong J; Penson, Alex A; Hughes, Chris C; Gordon, Benjamin B; Chen, Ziyu Z; Dong, Yiyu Y; Watson, Philip A PA; Alvim, Ricardo R; Elzein, Arijh A; Gao, Sizhi P SP; Cocco, Emiliano E; Santin, Alessandro D AD; Ostrovnaya, Irina I; Hsieh, James J JJ; Sagi, Irit I; Pietzak, Eugene J EJ; Hakimi, A Ari AA; Rosenberg, Jonathan E JE; Iyer, Gopa G; Vargas, Herbert A HA; Scaltriti, Maurizio M; Al-Ahmadie, Hikmat H; Solit, David B DB; Coleman, Jonathan A JA

Publication Date: 2020-04-24

Variant appearance in text: POLE: 1307C>A; P436H

PubMed Link: 32332851

Variant Present in the following documents:

• 41467_2020_15885_MOESM3_ESM.xlsx, sheet 5
• 41467_2020_15885_MOESM3_ESM.xlsx, sheet 3

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Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology

Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR

Publication Date: 2019-04

Variant appearance in text: POLE: P436H

PubMed Link: 31034466

Variant Present in the following documents:

• pcbi.1006981.s010.xlsx, sheet 1

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Phenotype of POLE-mutated endometrial cancer.

Plos One

Imboden, Sara S; Nastic, Denis D; Ghaderi, Mehran M; Rydberg, Filippa F; Rau, Tilman T TT; Mueller, Michael D MD; Epstein, Elisabeth E; Carlson, Joseph W JW

Publication Date: 2019

Variant appearance in text: POLE: 1307C>A; P436H

PubMed Link: 30917185

Variant Present in the following documents:

• Main text
• pone.0214318.pdf

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The genetic landscape of endometrial clear cell carcinomas.

The Journal Of Pathology

DeLair, Deborah F DF; Burke, Kathleen A KA; Selenica, Pier P; Lim, Raymond S RS; Scott, Sasinya N SN; Middha, Sumit S; Mohanty, Abhinita S AS; Cheng, Donavan T DT; Berger, Michael F MF; Soslow, Robert A RA; Weigelt, Britta B

Publication Date: 2017-10

Variant appearance in text: POLE: P436H

PubMed Link: 28718916

Variant Present in the following documents:

• Main text

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DNA Damage Response and Repair Gene Alterations Are Associated with Improved Survival in Patients with Platinum-Treated Advanced Urothelial Carcinoma.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Teo, Min Yuen MY; Bambury, Richard M RM; Zabor, Emily C EC; Jordan, Emmet E; Al-Ahmadie, Hikmat H; Boyd, Mariel E ME; Bouvier, Nancy N; Mullane, Stephanie A SA; Cha, Eugene K EK; Roper, Nitin N; Ostrovnaya, Irina I; Hyman, David M DM; Bochner, Bernard H BH; Arcila, Maria E ME; Solit, David B DB; Berger, Michael F MF; Bajorin, Dean F DF; Bellmunt, Joaquim J; Iyer, Gopakumar G; Rosenberg, Jonathan E JE

Publication Date: 2017-07-15

Variant appearance in text: POLE: P436H

PubMed Link: 28137924

Variant Present in the following documents:

• Main text

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POLD1: Central mediator of DNA replication and repair, and implication in cancer and other pathologies.

Gene

Nicolas, Emmanuelle E; Golemis, Erica A EA; Arora, Sanjeevani S

Publication Date: 2016-09-15

Variant appearance in text: POLE: P436H

PubMed Link: 27320729

Variant Present in the following documents:

• Main text
• main.pdf

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