POLE c.967A>G ;(p.T323A)

Variant ID: 12-133252733-T-C

NM_006231.2(POLE):c.967A>G;(p.T323A)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


Management and Prognosis of Patients with Recurrent or Persistent/Progressive Uterine Carcinosarcoma.

Current Oncology (Toronto, Ont.)
Tung, Hsiu-Jung HJ; Chiang, Chi-Yuan CY; Chang, Wei-Yang WY; Wu, Ren-Chin RC; Huang, Huei-Jean HJ; Yang, Lan-Yan LY; Lin, Chiao-Yun CY; Wang, Chun-Chieh CC; Chao, Angel A; Lai, Chyong-Huey CH
Publication Date: 2022-10-13

Variant appearance in text: POLE: T323A
PubMed Link: 36290878
Variant Present in the following documents:
  • Main text
  • curroncol-29-00601.pdf
View BVdb publication page



POLE/POLD1 mutation in non-exonuclease domain matters for predicting efficacy of immune-checkpoint-inhibitor therapy.

Clinical And Translational Medicine
Chen, Yan-Xing YX; Wang, Zi-Xian ZX; Yuan, Shu-Qiang SQ; Jiang, Teng-Jia TJ; Huang, You-Sheng YS; Xu, Rui-Hua RH; Wang, Feng F; Zhao, Qi Q
Publication Date: 2021-09

Variant appearance in text: POLE: T323A
PubMed Link: 34586735
Variant Present in the following documents:
  • CTM2-11-e524-s001.xlsx, sheet 2
View BVdb publication page



Interpretation of somatic POLE mutations in endometrial carcinoma.

The Journal Of Pathology
León-Castillo, Alicia A; Britton, Heidi H; McConechy, Melissa K MK; McAlpine, Jessica N JN; Nout, Remi R; Kommoss, Stefan S; Brucker, Sara Y SY; Carlson, Joseph W JW; Epstein, Elisabeth E; Rau, Tilman T TT; Bosse, Tjalling T; Church, David N DN; Gilks, C Blake CB
Publication Date: 2020-03

Variant appearance in text: POLE: 967A>G; T323A
PubMed Link: 31829442
Variant Present in the following documents:
  • Main text
  • PATH-250-323.pdf
  • PATH-250-323-s002.xlsx, sheet 2
View BVdb publication page



Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology
Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR
Publication Date: 2019-04

Variant appearance in text: POLE: T323A
PubMed Link: 31034466
Variant Present in the following documents:
  • pcbi.1006981.s010.xlsx, sheet 1
View BVdb publication page



Tumor Mutational Burden Guides Therapy in a Treatment Refractory POLE-Mutant Uterine Carcinosarcoma.

The Oncologist
Bhangoo, Munveer S MS; Boasberg, Peter P; Mehta, Pareen P; Elvin, Julia A JA; Ali, Siraj M SM; Wu, Winnie W; Klempner, Samuel J SJ
Publication Date: 2018-05

Variant appearance in text: POLE: T323A
PubMed Link: 29386312
Variant Present in the following documents:
  • Main text
View BVdb publication page



Multilevel genomics of colorectal cancers with microsatellite instability-clinical impact of JAK1 mutations and consensus molecular subtype 1.

Genome Medicine
Sveen, Anita A; Johannessen, Bjarne B; Tengs, Torstein T; Danielsen, Stine A SA; Eilertsen, Ina A IA; Lind, Guro E GE; Berg, Kaja C G KCG; Leithe, Edward E; Meza-Zepeda, Leonardo A LA; Domingo, Enric E; Myklebost, Ola O; Kerr, David D; Tomlinson, Ian I; Nesbakken, Arild A; Skotheim, Rolf I RI; Lothe, Ragnhild A RA
Publication Date: 2017-05-24

Variant appearance in text: POLE: T323A
PubMed Link: 28539123
Variant Present in the following documents:
  • 13073_2017_434_MOESM1_ESM.xlsx, sheet 5
View BVdb publication page