POLE c.375G>T ;(p.Q125H)

Variant ID: 12-133256588-C-A

NM_006231.2(POLE):c.375G>T;(p.Q125H)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


Ultra-mutated colorectal cancer patients with POLE driver mutations exhibit distinct clinical patterns.

Cancer Medicine
Hu, Hanguang H; Cai, Wen W; Wu, Dehao D; Hu, Wangxiong W; Dong Wang, Li L; Mao, Jianshan J; Zheng, Shu S; Ge, Weiting W
Publication Date: 2021-01

Variant appearance in text: POLE: Q125H
PubMed Link: 33125191
Variant Present in the following documents:
  • Main text
  • CAM4-10-135.pdf
View BVdb publication page



Clinicopathological and mutational analyses of colorectal cancer with mutations in the POLE gene.

Cancer Medicine
Hino, Hitoshi H; Shiomi, Akio A; Kusuhara, Masatoshi M; Kagawa, Hiroyasu H; Yamakawa, Yushi Y; Hatakeyama, Keiichi K; Kawabata, Takanori T; Oishi, Takuma T; Urakami, Kenichi K; Nagashima, Takeshi T; Kinugasa, Yusuke Y; Yamaguchi, Ken K
Publication Date: 2019-08

Variant appearance in text: POLE: Q125H
PubMed Link: 31240875
Variant Present in the following documents:
  • Main text
  • CAM4-8-4587.pdf
View BVdb publication page



Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology
Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR
Publication Date: 2019-04

Variant appearance in text: POLE: Q125H
PubMed Link: 31034466
Variant Present in the following documents:
  • pcbi.1006981.s010.xlsx, sheet 1
View BVdb publication page