POLE c.75C>A ;(p.A25=)

Variant ID: 12-133257853-G-T

NM_006231.2(POLE):c.75C>A;(p.A25=)

This variant was identified in 5 publications

View GRCh38 version.




Publications:


Landscape of Genetic Alterations Underlying Hallmark Signature Changes in Cancer Reveals TP53 Aneuploidy-driven Metabolic Reprogramming.

Cancer Research Communications
McClure, Marni B MB; Kogure, Yasunori Y; Ansari-Pour, Naser N; Saito, Yuki Y; Chao, Hann-Hsiang HH; Shepherd, Jonathan J; Tabata, Mariko M; Olopade, Olufunmilayo I OI; Wedge, David C DC; Hoadley, Katherine A KA; Perou, Charles M CM; Kataoka, Keisuke K
Publication Date: 2023-02

Variant appearance in text: POLE: A25A
PubMed Link: 36860655
Variant Present in the following documents:
  • crc-22-0073-s01.xlsx, sheet 2
View BVdb publication page



A computational and structural analysis of germline and somatic variants affecting the DDR mechanism, and their impact on human diseases.

Scientific Reports
Magraner-Pardo, Lorena L; Laskowski, Roman A RA; Pons, Tirso T; Thornton, Janet M JM
Publication Date: 2021-07-12

Variant appearance in text: POLE: A25A
PubMed Link: 34253785
Variant Present in the following documents:
  • 41598_2021_93715_MOESM2_ESM.xlsx, sheet 10
View BVdb publication page



Elevated expression of LPCAT1 predicts a poor prognosis and is correlated with the tumour microenvironment in endometrial cancer.

Cancer Cell International
Zhao, Tianyi T; Zhang, Yifang Y; Ma, Xiaohong X; Wei, Lina L; Hou, Yixin Y; Sun, Rui R; Jiang, Jie J
Publication Date: 2021-05-20

Variant appearance in text: POLE: a25a
PubMed Link: 34016103
Variant Present in the following documents:
  • 12935_2021_1965_MOESM4_ESM.xlsx, sheet 1
View BVdb publication page



Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas.

Cell Reports
Way, Gregory P GP; Sanchez-Vega, Francisco F; La, Konnor K; Armenia, Joshua J; Chatila, Walid K WK; Luna, Augustin A; Sander, Chris C; Cherniack, Andrew D AD; Mina, Marco M; Ciriello, Giovanni G; Schultz, Nikolaus N; , ; Sanchez, Yolanda Y; Greene, Casey S CS
Publication Date: 2018-04-03

Variant appearance in text: POLE: A25A
PubMed Link: 29617658
Variant Present in the following documents:
  • NIHMS958974-supplement-3.xlsx, sheet 1
View BVdb publication page



Mutation Clusters from Cancer Exome.

Genes
Kakushadze, Zura Z; Yu, Willie W
Publication Date: 2017-08-15

Variant appearance in text: POLE: A25A
PubMed Link: 28809811
Variant Present in the following documents:
  • Main text
  • genes-08-00201.pdf
View BVdb publication page