POLE c.31_32delinsCA ;(p.A11Q)

Variant ID: 12-133263870-GC-TG

NM_006231.2(POLE):c.31_32delinsCA;(p.A11Q)

This variant was identified in 7 publications

View GRCh38 version.




Publications:


Elevated expression of LPCAT1 predicts a poor prognosis and is correlated with the tumour microenvironment in endometrial cancer.

Cancer Cell International
Zhao, Tianyi T; Zhang, Yifang Y; Ma, Xiaohong X; Wei, Lina L; Hou, Yixin Y; Sun, Rui R; Jiang, Jie J
Publication Date: 2021-05-20

Variant appearance in text: POLE: A11Q
PubMed Link: 34016103
Variant Present in the following documents:
  • 12935_2021_1965_MOESM4_ESM.xlsx, sheet 1
View BVdb publication page



Mutational processes of distinct POLE exonuclease domain mutants drive an enrichment of a specific TP53 mutation in colorectal cancer.

Plos Genetics
Fang, Hu H; Barbour, Jayne A JA; Poulos, Rebecca C RC; Katainen, Riku R; Aaltonen, Lauri A LA; Wong, Jason W H JWH
Publication Date: 2020-02

Variant appearance in text: POLE: A11Q
PubMed Link: 32012149
Variant Present in the following documents:
  • pgen.1008572.s015.xlsx, sheet 1
View BVdb publication page



Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas.

Cell Reports
Way, Gregory P GP; Sanchez-Vega, Francisco F; La, Konnor K; Armenia, Joshua J; Chatila, Walid K WK; Luna, Augustin A; Sander, Chris C; Cherniack, Andrew D AD; Mina, Marco M; Ciriello, Giovanni G; Schultz, Nikolaus N; , ; Sanchez, Yolanda Y; Greene, Casey S CS
Publication Date: 2018-04-03

Variant appearance in text: POLE: A11Q
PubMed Link: 29617658
Variant Present in the following documents:
  • NIHMS958974-supplement-3.xlsx, sheet 1
View BVdb publication page



Ornithine decarboxylase as a therapeutic target for endometrial cancer.

Plos One
Kim, Hong Im HI; Schultz, Chad R CR; Buras, Andrea L AL; Friedman, Elizabeth E; Fedorko, Alyssa A; Seamon, Leigh L; Chandramouli, Gadisetti V R GVR; Maxwell, G Larry GL; Bachmann, André S AS; Risinger, John I JI
Publication Date: 2017

Variant appearance in text: POLE: A11Q
PubMed Link: 29240775
Variant Present in the following documents:
  • pone.0189044.s004.xlsx, sheet 3
View BVdb publication page



Mutation Clusters from Cancer Exome.

Genes
Kakushadze, Zura Z; Yu, Willie W
Publication Date: 2017-08-15

Variant appearance in text: POLE: A11Q
PubMed Link: 28809811
Variant Present in the following documents:
  • Main text
View BVdb publication page



Long non-coding RNA profiling links subgroup classification of endometrioid endometrial carcinomas with trithorax and polycomb complex aberrations.

Oncotarget
Jiang, Yunyun Y; Malouf, Gabriel G GG; Zhang, Jianping J; Zheng, Xiaofeng X; Chen, Yunxin Y; Thompson, Erika J EJ; Weinstein, John N JN; Yuan, Ying Y; Spano, Jean-Philippe JP; Broaddus, Russell R; Tannir, Nizar M NM; Khayat, David D; Lu, Karen H KH; Su, Xiaoping X
Publication Date: 2015-11-24

Variant appearance in text: POLE: A11Q
PubMed Link: 26431491
Variant Present in the following documents:
  • oncotarget-06-39865-s002.xlsx, sheet 11
View BVdb publication page



A TrkB-STAT3-miR-204-5p regulatory circuitry controls proliferation and invasion of endometrial carcinoma cells.

Molecular Cancer
Bao, Wei W; Wang, Hui-Hui HH; Tian, Fu-Ju FJ; He, Xiao-Ying XY; Qiu, Mei-Ting MT; Wang, Jing-Yun JY; Zhang, Hui-Juan HJ; Wang, Li-Hua LH; Wan, Xiao-Ping XP
Publication Date: 2013-12-09

Variant appearance in text: POLE: A11Q
PubMed Link: 24321270
Variant Present in the following documents:
  • 1476-4598-12-155-S5.xls, sheet 5
  • 1476-4598-12-155-S5.xls, sheet 4
View BVdb publication page