Variant ID: 12-21368722-T-C

NM_006446.4(SLCO1B1):c.1498-1331T>C

This variant was identified in 79 publications




Publications:


Pharmacogenetics of Statin-Induced Myotoxicity.

Frontiers In Genetics
PS Kee, PKL Chin, MA Kennedy, SDS Maggo
Publication Date: 2020

Variant appearance in text: rs4363657
PubMed Link: 33193687
Variant Present in the following documents:
  • Main text
View BVdb publication page



Corrigendum.

Personalized Medicine
.
Publication Date: 2020-09

Variant appearance in text: rs4363657
PubMed Link: 32915689
Variant Present in the following documents:
  • Main text
View BVdb publication page



Shared mechanisms for cognitive impairment and physical frailty: A model for complex systems.

Alzheimer'S & Dementia (New York, N. Y.)
L Sargent, M Nalls, EJ Amella, PW Slattum, M Mueller, S Bandinelli, Q Tian, T Swift-Scanlan, SK Lageman, A Singleton
Publication Date: 2020

Variant appearance in text: rs4363657
PubMed Link: 32685657
Variant Present in the following documents:
  • Main text
View BVdb publication page



The influence of genetic polymorphisms in drug metabolism enzymes and transporters on the pharmacokinetics of different fluvastatin formulations.

Asian Journal Of Pharmaceutical Sciences
Q Xiang, W Wu, N Zhao, C Li, J Xu, L Ma, X Zhang, Q Xie, Z Zhang, J Wang, W Xu, X Zhao, Y Cui
Publication Date: 2020-03

Variant appearance in text: rs4363657
PubMed Link: 32373204
Variant Present in the following documents:
  • Main text
View BVdb publication page



A Genome-wide Association Study of Circulating Levels of Atorvastatin and Its Major Metabolites.

Clinical Pharmacology And Therapeutics
RM Turner, V Fontana, JE Zhang, D Carr, P Yin, R FitzGerald, AP Morris, M Pirmohamed
Publication Date: 2020-08

Variant appearance in text: rs4363657
PubMed Link: 32128760
Variant Present in the following documents:
  • Supplemental file
View BVdb publication page



A Look at Genetic Linkage between Clozapine-induced Agranulocytosis, Malignant Hyperthermia, Neuroleptic Malignant Syndrome, and Statin-induced Myopathy.

Innovations In Clinical Neuroscience
N Pothen, S Kansal, T Rais, S Doumas, R Solhkhah
Publication Date: 2019-11-01

Variant appearance in text: rs4363657
PubMed Link: 32082940
Variant Present in the following documents:
  • Main text
View BVdb publication page



Metabolic GWAS of elite athletes reveals novel genetically-influenced metabolites associated with athletic performance.

Scientific Reports
F Al-Khelaifi, I Diboun, F Donati, F Botrè, D Abraham, A Hingorani, O Albagha, C Georgakopoulos, K Suhre, NA Yousri, MA Elrayess
Publication Date: 2019-12-27

Variant appearance in text: rs4363657
PubMed Link: 31882771
Variant Present in the following documents:
  • Supplemental file
  • Main text
  • 41598_2019_Article_56496.pdf
View BVdb publication page



microRNA-206 modulates the hepatic expression of the organic anion-transporting polypeptide 1B1.

Liver International : Official Journal Of The International Association For The Study Of The Liver
T El Saadany, B van Rosmalen, Z Gai, C Hiller, J Verheij, B Stieger, T van Gulik, M Visentin, GA Kullak-Ublick
Publication Date: 2019-12

Variant appearance in text: rs4363657
PubMed Link: 31408569
Variant Present in the following documents:
  • Supplemental file
View BVdb publication page



Impact of pharmacogenetics on statin-induced myopathy in South-Indian subjects.

Indian Heart Journal
N Ramakumari, B Indumathi, SK Katkam, VK Kutala
Publication Date: 2018-12

Variant appearance in text: rs4363657
PubMed Link: 30595243
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Pharmacogenomics of Medications Commonly Used in the Intensive Care Unit.

Frontiers In Pharmacology
S Zhou, DJ Skaar, PA Jacobson, RS Huang
Publication Date: 2018

Variant appearance in text: rs4363657
PubMed Link: 30564130
Variant Present in the following documents:
  • Main text
View BVdb publication page



Differential diagnosis of idiopathic inflammatory myopathies in adults - the first step when approaching a patient with muscle weakness.

Reumatologia
P Szczęsny, K Świerkocka, M Olesińska
Publication Date: 2018

Variant appearance in text: rs4363657
PubMed Link: 30505013
Variant Present in the following documents:
  • Main text
View BVdb publication page



Effects of SLCO1B1 and GATM gene variants on rosuvastatin-induced myopathy are unrelated to high plasma exposure of rosuvastatin and its metabolites.

Acta Pharmacologica Sinica
X Bai, B Zhang, P Wang, GL Wang, JL Li, DS Wen, XZ Long, HS Sun, YB Liu, M Huang, SL Zhong
Publication Date: 2019-04

Variant appearance in text: rs4363657
PubMed Link: 29950617
Variant Present in the following documents:
  • Main text
View BVdb publication page



CRISPR-Cas12a-assisted nucleic acid detection.

Cell Discovery
SY Li, QX Cheng, JM Wang, XY Li, ZL Zhang, S Gao, RB Cao, GP Zhao, J Wang
Publication Date: 2018

Variant appearance in text: rs4363657
PubMed Link: 29707234
Variant Present in the following documents:
  • 41421_2018_28_MOESM1_ESM.pdf
View BVdb publication page



The role of genetic variation of human metabolism for BMI, mental traits and mental disorders.

Molecular Metabolism
J Hebebrand, T Peters, D Schijven, M Hebebrand, C Grasemann, TW Winkler, IM Heid, J Antel, M Föcker, L Tegeler, L Brauner, RAH Adan, JJ Luykx, CU Correll, IR König, A Hinney, L Libuda
Publication Date: 2018-06

Variant appearance in text: rs4363657
PubMed Link: 29673576
Variant Present in the following documents:
  • mmc1.xlsx
View BVdb publication page



Pharmacogenetic landscape of Metabolic Syndrome components drug response in Tunisia and comparison with worldwide populations.

Plos One
H Jmel, L Romdhane, Y Ben Halima, M Hechmi, C Naouali, H Dallali, Y Hamdi, J Shan, A Abid, H Jamoussi, S Trabelsi, L Chouchane, D Luiselli, S Abdelhak, R Kefi
Publication Date: 2018

Variant appearance in text: rs4363657
PubMed Link: 29652911
Variant Present in the following documents:
  • Main text
View BVdb publication page



PheWAS and Beyond: The Landscape of Associations with Medical Diagnoses and Clinical Measures across 38,662 Individuals from Geisinger.

American Journal Of Human Genetics
A Verma, A Lucas, SS Verma, Y Zhang, N Josyula, A Khan, DN Hartzel, DR Lavage, J Leader, MD Ritchie, SA Pendergrass
Publication Date: 2018-04-05

Variant appearance in text: rs4363657
PubMed Link: 29606303
Variant Present in the following documents:
  • mmc2.xlsx
View BVdb publication page



The effect of genetic variants on the relationship between statins and breast cancer in postmenopausal women in the Women's Health Initiative observational study.

Breast Cancer Research And Treatment
CH Bock, AM Jay, G Dyson, JL Beebe-Dimmer, ML Cote, L Hou, BV Howard, P Desai, K Purrington, R Prentice, MS Simon
Publication Date: 2018-02

Variant appearance in text: rs4363657
PubMed Link: 29063981
Variant Present in the following documents:
  • Main text
View BVdb publication page



Pharmacogenetics in Cardiovascular Medicine.

Current Genetic Medicine Reports
S Tuteja, N Limdi
Publication Date: 2016-09

Variant appearance in text: rs4363657
PubMed Link: 29057167
Variant Present in the following documents:
  • Main text
View BVdb publication page



Uncover the Underlying Mechanism of Drug-Induced Myopathy by Using Systems Biology Approaches.

International Journal Of Genomics
D Li, A Li, H Zhou, X Wang, P Li, S Bi, Y Teng
Publication Date: 2017

Variant appearance in text: rs4363657
PubMed Link: 28831389
Variant Present in the following documents:
  • Main text
View BVdb publication page



Precision medicine and pharmacogenetics: what does oncology have that addiction medicine does not?

Addiction (Abingdon, England)
HR Kranzler, RV Smith, R Schnoll, A Moustafa, E Greenstreet-Akman
Publication Date: 2017-12

Variant appearance in text: rs4363657
PubMed Link: 28431457
Variant Present in the following documents:
  • Main text
View BVdb publication page



SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+ breast cancer: genome-wide association studies of the estrone pathway.

Breast Cancer Research And Treatment
TM Dudenkov, JN Ingle, AU Buzdar, ME Robson, M Kubo, I Ibrahim-Zada, A Batzler, GD Jenkins, TL Pietrzak, EE Carlson, P Barman, MP Goetz, DW Northfelt, A Moreno-Aspita, CV Williard, KR Kalari, Y Nakamura, L Wang, RM Weinshilboum
Publication Date: 2017-07

Variant appearance in text: rs4363657
PubMed Link: 28429243
Variant Present in the following documents:
  • NIHMS898876-supplement-supplemental.doc
View BVdb publication page



Molecular pathways associated with blood pressure and hexadecanedioate levels.

Plos One
C Menni, SJ Metrustry, G Ehret, AF Dominiczak, P Chowienczyk, TD Spector, S Padmanabhan, AM Valdes
Publication Date: 2017

Variant appearance in text: rs4363657
PubMed Link: 28403188
Variant Present in the following documents:
  • Main text
View BVdb publication page



A genetic risk score is significantly associated with statin therapy response in the elderly population.

Clinical Genetics
DM Ciuculete, M Bandstein, C Benedict, G Waeber, P Vollenweider, L Lind, HB Schiöth, J Mwinyi
Publication Date: 2017-03

Variant appearance in text: rs4363657
PubMed Link: 27943270
Variant Present in the following documents:
  • Supplemental file
View BVdb publication page



The Importance of Patient-Specific Factors for Hepatic Drug Response and Toxicity.

International Journal Of Molecular Sciences
VM Lauschke, M Ingelman-Sundberg
Publication Date: 2016-10-12

Variant appearance in text: rs4363657
PubMed Link: 27754327
Variant Present in the following documents:
  • Main text
View BVdb publication page



Racial Differences in the Cholesterol-Lowering Effect of Statin.

Journal Of Atherosclerosis And Thrombosis
R Naito, K Miyauchi, H Daida
Publication Date: 2017-01-01

Variant appearance in text: rs4363657
PubMed Link: 27733728
Variant Present in the following documents:
  • Main text
View BVdb publication page



Laboratory Medicine in the Clinical Decision Support for Treatment of Hypercholesterolemia: Pharmacogenetics of Statins.

Clinics In Laboratory Medicine
G Ruaño, R Seip, A Windemuth, AH Wu, PD Thompson
Publication Date: 2016-09

Variant appearance in text: rs4363657
PubMed Link: 27514463
Variant Present in the following documents:
  • Main text
View BVdb publication page



Molecular mechanisms of statin intolerance.

Archives Of Medical Science : Ams
A Gluba-Brzozka, B Franczyk, PP Toth, J Rysz, M Banach
Publication Date: 2016-06-01

Variant appearance in text: rs4363657
PubMed Link: 27279860
Variant Present in the following documents:
  • Main text
View BVdb publication page



Rare genetic variants in cellular transporters, metabolic enzymes, and nuclear receptors can be important determinants of interindividual differences in drug response.

Genetics In Medicine : Official Journal Of The American College Of Medical Genetics
M Kozyra, M Ingelman-Sundberg, VM Lauschke
Publication Date: 2017-01

Variant appearance in text: rs4363657
PubMed Link: 27101133
Variant Present in the following documents:
  • Supplemental file
View BVdb publication page



Common and rare variants associating with serum levels of creatine kinase and lactate dehydrogenase.

Nature Communications
RP Kristjansson, A Oddsson, H Helgason, G Sveinbjornsson, GA Arnadottir, BO Jensson, A Jonasdottir, A Jonasdottir, G Bragi Walters, G Sulem, A Oskarsdottir, S Benonisdottir, OB Davidsson, G Masson, OT Magnusson, H Holm, O Sigurdardottir, I Jonsdottir, GI Eyjolfsson, I Olafsson, DF Gudbjartsson, U Thorsteinsdottir, P Sulem, K Stefansson
Publication Date: 2016-02-03

Variant appearance in text: rs4363657
PubMed Link: 26838040
Variant Present in the following documents:
  • ncomms10572-s1.pdf
  • Main text
View BVdb publication page



Clinical Perspectives on Targeting Therapies for Personalized Medicine.

Advances In Protein Chemistry And Structural Biology
DR Singer, ZM Zaïr
Publication Date: 2016

Variant appearance in text: rs4363657
PubMed Link: 26827603
Variant Present in the following documents:
  • Main text
View BVdb publication page



The Interaction Between Statins and Exercise: Mechanisms and Strategies to Counter the Musculoskeletal Side Effects of This Combination Therapy.

The Ochsner Journal
RE Deichmann, CJ Lavie, T Asher, JJ DiNicolantonio, JH O'Keefe, PD Thompson
Publication Date: 2015

Variant appearance in text: rs4363657
PubMed Link: 26730228
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic diversity of variants involved in drug response and metabolism in Sri Lankan populations: implications for clinical implementation of pharmacogenomics.

Pharmacogenetics And Genomics
SL Chan, N Samaranayake, CJ Ross, MT Toh, B Carleton, MR Hayden, YY Teo, VH Dissanayake, LR Brunham
Publication Date: 2016-01

Variant appearance in text: rs4363657
PubMed Link: 26444257
Variant Present in the following documents:
  • fpc-26-28-s010.docx
  • fpc-26-28-s009.docx
View BVdb publication page



HMGCR rs17671591 SNP Determines Lower Plasma LDL-C after Atorvastatin Therapy in Chilean Individuals.

Basic & Clinical Pharmacology & Toxicology
A Cuevas, C Fernández, L Ferrada, T Zambrano, A Rosales, N Saavedra, LA Salazar
Publication Date: 2016-04

Variant appearance in text: rs4363657
PubMed Link: 26408409
Variant Present in the following documents:
  • Supplemental file
View BVdb publication page



Association Between SLCO1B1 Gene T521C Polymorphism and Statin-Related Myopathy Risk: A Meta-Analysis of Case-Control Studies.

Medicine
Q Hou, S Li, L Li, Y Li, X Sun, H Tian
Publication Date: 2015-09

Variant appearance in text: rs4363657
PubMed Link: 26376374
Variant Present in the following documents:
  • Main text
View BVdb publication page



A 68-year old male presenting with rhabdomyolysis-associated acute kidney injury following concomitant use of elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate and pravastatin/fenofibrate: a case report.

Journal Of Medical Case Reports
V Suttels, E Florence, J Leys, M Vekemans, J Van den Ende, E Vlieghe, C Kenyon
Publication Date: 2015-09-08

Variant appearance in text: rs4363657
PubMed Link: 26347243
Variant Present in the following documents:
  • Main text
View BVdb publication page



Marked differences in frequencies of statin therapy relevant SLCO1B1 variants and haplotypes between Roma and Hungarian populations.

Bmc Genetics
A Nagy, C Sipeky, R Szalai, BI Melegh, P Matyas, A Ganczer, K Toth, B Melegh
Publication Date: 2015-09-03

Variant appearance in text: SLCO1B1: 1498-1331T>C; rs4363657
PubMed Link: 26334733
Variant Present in the following documents:
  • Main text
View BVdb publication page



Evidence for Clinical Implementation of Pharmacogenomics in Cardiac Drugs.

Mayo Clinic Proceedings
AL Kaufman, J Spitz, M Jacobs, M Sorrentino, S Yuen, K Danahey, D Saner, TE Klein, RB Altman, MJ Ratain, PH O'Donnell
Publication Date: 2015-06

Variant appearance in text: rs4363657
PubMed Link: 26046407
Variant Present in the following documents:
  • NIHMS676556-supplement-4.pdf
View BVdb publication page



SLCO1B1 polymorphism is not associated with risk of statin-induced myalgia/myopathy in a Czech population.

Medical Science Monitor : International Medical Journal Of Experimental And Clinical Research
JA Hubáček, D Dlouhá, V Adámková, L Zlatohlavek, O Viklický, P Hrubá, R Češka, M Vrablík
Publication Date: 2015-05-20

Variant appearance in text: rs4363657
PubMed Link: 25992810
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genotype-based clinical trials in cardiovascular disease.

Nature Reviews. Cardiology
NL Pereira, DJ Sargent, ME Farkouh, CS Rihal
Publication Date: 2015-08

Variant appearance in text: rs4363657
PubMed Link: 25940926
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genomics and metabolomics of muscular mass in a community-based sample of UK females.

European Journal Of Human Genetics : Ejhg
M Korostishevsky, CJ Steves, I Malkin, T Spector, FM Williams, G Livshits
Publication Date: 2016-02

Variant appearance in text: rs4363657
PubMed Link: 25898920
Variant Present in the following documents:
  • Main text
  • ejhg201585x1.pdf
View BVdb publication page



Statin pharmacogenomics: opportunities to improve patient outcomes and healthcare costs with genetic testing.

Journal Of Personalized Medicine
WJ Canestaro, DG Brooks, D Chaplin, NK Choudhry, E Lawler, L Martell, T Brennan, ER Wassman
Publication Date: 2012-10-17

Variant appearance in text: rs4363657
PubMed Link: 25562358
Variant Present in the following documents:
  • Main text
View BVdb publication page



A genome-wide pleiotropy scan for prostate cancer risk.

European Urology
OA Panagiotou, RC Travis, D Campa, SI Berndt, S Lindstrom, P Kraft, FR Schumacher, A Siddiq, SI Papatheodorou, JL Stanford, D Albanes, J Virtamo, SJ Weinstein, WR Diver, SM Gapstur, VL Stevens, H Boeing, HB Bueno-de-Mesquita, A Barricarte Gurrea, R Kaaks, KT Khaw, V Krogh, K Overvad, E Riboli, D Trichopoulos, E Giovannucci, M Stampfer, C Haiman, B Henderson, L Le Marchand, JM Gaziano, DJ Hunter, S Koutros, M Yeager, RN Hoover, , SJ Chanock, S Wacholder, TJ Key, KK Tsilidis
Publication Date: 2015-04

Variant appearance in text: rs4363657
PubMed Link: 25277271
Variant Present in the following documents:
  • NIHMS628904-supplement-Suppl__1.doc
View BVdb publication page



Mechanisms and assessment of statin-related muscular adverse effects.

British Journal Of Clinical Pharmacology
D Moßhammer, E Schaeffeler, M Schwab, K Mörike
Publication Date: 2014-09

Variant appearance in text: rs4363657
PubMed Link: 25069381
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic factors affecting statin concentrations and subsequent myopathy: a HuGENet systematic review.

Genetics In Medicine : Official Journal Of The American College Of Medical Genetics
WJ Canestaro, MA Austin, KE Thummel
Publication Date: 2014-11

Variant appearance in text: rs4363657
PubMed Link: 24810685
Variant Present in the following documents:
  • Main text
View BVdb publication page



An assessment by the Statin Muscle Safety Task Force: 2014 update.

Journal Of Clinical Lipidology
RS Rosenson, SK Baker, TA Jacobson, SL Kopecky, BA Parker, The National Lipid Association's Muscle Safety Expert Panel
Publication Date: 2014

Variant appearance in text: rs4363657
PubMed Link: 24793443
Variant Present in the following documents:
  • Supplemental file
View BVdb publication page



Associations of novel genetic variations in the folate-related and ARID5B genes with the pharmacokinetics and toxicity of high-dose methotrexate in paediatric acute lymphoblastic leukaemia.

British Journal Of Haematology
K Csordas, O Lautner-Csorba, AF Semsei, A Harnos, M Hegyi, DJ Erdelyi, OT Eipel, C Szalai, GT Kovacs
Publication Date: 2014-08

Variant appearance in text: rs4363657
PubMed Link: 24712521
Variant Present in the following documents:
  • Supplemental file
View BVdb publication page



Genomic convergence and network analysis approach to identify candidate genes in Alzheimer's disease.

Bmc Genomics
P Talwar, Y Silla, S Grover, M Gupta, R Agarwal, S Kushwaha, R Kukreti
Publication Date: 2014-03-15

Variant appearance in text: rs4363657
PubMed Link: 24628925
Variant Present in the following documents:
  • 12864_2013_7037_MOESM1_ESM.xlsx
View BVdb publication page



Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data.

Nature Biotechnology
JC Denny, L Bastarache, MD Ritchie, RJ Carroll, R Zink, JD Mosley, JR Field, JM Pulley, AH Ramirez, E Bowton, MA Basford, DS Carrell, PL Peissig, AN Kho, JA Pacheco, LV Rasmussen, DR Crosslin, PK Crane, J Pathak, SJ Bielinski, SA Pendergrass, H Xu, LA Hindorff, R Li, TA Manolio, CG Chute, RL Chisholm, EB Larson, GP Jarvik, MH Brilliant, CA McCarty, IJ Kullo, JL Haines, DC Crawford, DR Masys, DM Roden
Publication Date: 2013-12

Variant appearance in text: rs4363657
PubMed Link: 24270849
Variant Present in the following documents:
  • NIHMS561785-supplement-supplementary_data.pdf
View BVdb publication page



SLCO1B1 genetic variant associated with statin-induced myopathy: a proof-of-concept study using the clinical practice research datalink.

Clinical Pharmacology And Therapeutics
DF Carr, H O'Meara, AL Jorgensen, J Campbell, M Hobbs, G McCann, T van Staa, M Pirmohamed
Publication Date: 2013-12

Variant appearance in text: rs4363657
PubMed Link: 23942138
Variant Present in the following documents:
  • Main text
View BVdb publication page



Roles of genetic polymorphisms in the folate pathway in childhood acute lymphoblastic leukemia evaluated by Bayesian relevance and effect size analysis.

Plos One
O Lautner-Csorba, A Gézsi, DJ Erdélyi, G Hullám, P Antal, ÁF Semsei, N Kutszegi, G Kovács, A Falus, C Szalai
Publication Date: 2013

Variant appearance in text: rs4363657
PubMed Link: 23940529
Variant Present in the following documents:
  • pone.0069843.s012.xls
  • pone.0069843.s010.xls
  • pone.0069843.s007.doc
  • Main text
  • pone.0069843.s006.doc
View BVdb publication page



ATP5H/KCTD2 locus is associated with Alzheimer's disease risk.

Molecular Psychiatry
M Boada, C Antúnez, R Ramírez-Lorca, AL DeStefano, A González-Pérez, J Gayán, J López-Arrieta, MA Ikram, I Hernández, J Marín, JJ Galán, JC Bis, A Mauleón, M Rosende-Roca, C Moreno-Rey, V Gudnasson, FJ Morón, J Velasco, JM Carrasco, M Alegret, A Espinosa, G Vinyes, A Lafuente, L Vargas, AL Fitzpatrick, , LJ Launer, ME Sáez, E Vázquez, JT Becker, OL López, M Serrano-Ríos, L Tárraga, CM van Duijn, LM Real, S Seshadri, A Ruiz
Publication Date: 2014-06

Variant appearance in text: rs4363657
PubMed Link: 23857120
Variant Present in the following documents:
  • mp201386x9.xls
View BVdb publication page



GStream: improving SNP and CNV coverage on genome-wide association studies.

Plos One
A Alonso, S Marsal, R Tortosa, O Canela-Xandri, A Julià
Publication Date: 2013

Variant appearance in text: rs4363657
PubMed Link: 23844243
Variant Present in the following documents:
  • pone.0068822.s013.xlsx
View BVdb publication page



Pharmacogenomics and cardiovascular disease.

Current Cardiology Reports
P Weeke, DM Roden
Publication Date: 2013-07

Variant appearance in text: rs4363657
PubMed Link: 23689943
Variant Present in the following documents:
  • Main text
View BVdb publication page



Pharmacogenetics and cardiovascular disease--implications for personalized medicine.

Pharmacological Reviews
JA Johnson, LH Cavallari
Publication Date: 2013-07

Variant appearance in text: rs4363657
PubMed Link: 23686351
Variant Present in the following documents:
  • Main text
View BVdb publication page



Predicting the cost and pace of pharmacogenomic advances: an evidence-based study.

Clinical Chemistry
R Arnaout, TP Buck, P Roulette, VP Sukhatme
Publication Date: 2013-04

Variant appearance in text: rs4363657
PubMed Link: 23230323
Variant Present in the following documents:
  • Supplemental file
View BVdb publication page



Pharmacogenomics of drug metabolizing enzymes and transporters: implications for cancer therapy.

Pharmacogenomics And Personalized Medicine
J Li, MH Bluth
Publication Date: 2011

Variant appearance in text: rs4363657
PubMed Link: 23226051
Variant Present in the following documents:
  • Main text
View BVdb publication page



Effect of statins on skeletal muscle: exercise, myopathy, and muscle outcomes.

Exercise And Sport Sciences Reviews
BA Parker, PD Thompson
Publication Date: 2012-10

Variant appearance in text: rs4363657
PubMed Link: 23000957
Variant Present in the following documents:
  • Main text
View BVdb publication page



Pharmacogenomics of adverse drug reactions: implementing personalized medicine.

Human Molecular Genetics
CY Wei, MT Lee, YT Chen
Publication Date: 2012-10-15

Variant appearance in text: rs4363657
PubMed Link: 22907657
Variant Present in the following documents:
  • Supplemental file
View BVdb publication page



Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants.

Plos Genetics
F Zou, HS Chai, CS Younkin, M Allen, J Crook, VS Pankratz, MM Carrasquillo, CN Rowley, AA Nair, S Middha, S Maharjan, T Nguyen, L Ma, KG Malphrus, R Palusak, S Lincoln, G Bisceglio, C Georgescu, N Kouri, CP Kolbert, J Jen, JL Haines, R Mayeux, MA Pericak-Vance, LA Farrer, GD Schellenberg, , RC Petersen, NR Graff-Radford, DW Dickson, SG Younkin, N Ertekin-Taner
Publication Date: 2012

Variant appearance in text: rs4363657
PubMed Link: 22685416
Variant Present in the following documents:
  • pgen.1002707.s006.pdf
View BVdb publication page



Pharmacogenetics of statins: achievements, whole-genome analyses and future perspectives.

Pharmacogenomics
I Postmus, JJ Verschuren, AJ de Craen, PE Slagboom, RG Westendorp, JW Jukema, S Trompet
Publication Date: 2012-05

Variant appearance in text: rs4363657
PubMed Link: 22594514
Variant Present in the following documents:
  • Supplemental file
View BVdb publication page



Clinical utility of pharmacogenetic biomarkers in cardiovascular therapeutics: a challenge for clinical implementation.

Pharmacogenomics
FS Ong, JL Deignan, JZ Kuo, KE Bernstein, JI Rotter, WW Grody, K Das
Publication Date: 2012-03

Variant appearance in text: rs4363657
PubMed Link: 22380001
Variant Present in the following documents:
  • Main text
View BVdb publication page



Stroke Genetics Update: 2011.

Current Cardiovascular Risk Reports
JW Cole, JF Meschia
Publication Date: 2011-12-01

Variant appearance in text: rs4363657
PubMed Link: 22163054
Variant Present in the following documents:
  • Main text
View BVdb publication page



SLCO1B1 rs4149056 polymorphism associated with statin-induced myopathy is differently distributed according to ethnicity in the Brazilian general population: Amerindians as a high risk ethnic group.

Bmc Medical Genetics
PC Santos, RA Soares, RM Nascimento, GL Machado-Coelho, JG Mill, JE Krieger, AC Pereira
Publication Date: 2011-10-12

Variant appearance in text: rs4363657
PubMed Link: 21992719
Variant Present in the following documents:
  • Main text
View BVdb publication page



The impact of pharmacogenomics on the management of cardiac disease.

Clinical Pharmacology And Therapeutics
NL Pereira, RM Weinshilboum
Publication Date: 2011-10

Variant appearance in text: rs4363657
PubMed Link: 21934720
Variant Present in the following documents:
  • Main text
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Pharmacogenomics: application to the management of cardiovascular disease.

Clinical Pharmacology And Therapeutics
JA Johnson, LH Cavallari, AL Beitelshees, JP Lewis, AR Shuldiner, DM Roden
Publication Date: 2011-10

Variant appearance in text: rs4363657
PubMed Link: 21918509
Variant Present in the following documents:
  • Main text
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Association of common variants in the human eyes shut ortholog (EYS) with statin-induced myopathy: evidence for additional functions of EYS.

Muscle & Nerve
PJ Isackson, HM Ochs-Balcom, C Ma, JB Harley, W Peltier, M Tarnopolsky, N Sripathi, RL Wortmann, Z Simmons, JD Wilson, SA Smith, A Barboi, E Fine, A Baer, S Baker, K Kaufman, B Cobb, JR Kilpatrick, GD Vladutiu
Publication Date: 2011-10

Variant appearance in text: rs4363657
PubMed Link: 21826682
Variant Present in the following documents:
  • Main text
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Mayo Genome Consortia: a genotype-phenotype resource for genome-wide association studies with an application to the analysis of circulating bilirubin levels.

Mayo Clinic Proceedings
SJ Bielinski, HS Chai, J Pathak, JA Talwalkar, PJ Limburg, RE Gullerud, H Sicotte, EW Klee, JL Ross, JP Kocher, IJ Kullo, JA Heit, GM Petersen, M de Andrade, CG Chute
Publication Date: 2011-07

Variant appearance in text: rs4363657
PubMed Link: 21646302
Variant Present in the following documents:
  • Main text
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Pharmacogenomics: the genetics of variable drug responses.

Circulation
DM Roden, RA Wilke, HK Kroemer, CM Stein
Publication Date: 2011-04-19

Variant appearance in text: rs4363657
PubMed Link: 21502584
Variant Present in the following documents:
  • Main text
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Cerivastatin, genetic variants, and the risk of rhabdomyolysis.

Pharmacogenetics And Genomics
KD Marciante, JP Durda, SR Heckbert, T Lumley, K Rice, B McKnight, RA Totah, B Tamraz, DL Kroetz, H Fukushima, R Kaspera, JC Bis, NL Glazer, G Li, TR Austin, KD Taylor, JI Rotter, CE Jaquish, PY Kwok, RP Tracy, BM Psaty
Publication Date: 2011-05

Variant appearance in text: rs4363657
PubMed Link: 21386754
Variant Present in the following documents:
  • Main text
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Pharmacogenomics: a systems approach.

Wiley Interdisciplinary Reviews. Systems Biology And Medicine
L Wang
Publication Date: 2010

Variant appearance in text: rs4363657
PubMed Link: 20836007
Variant Present in the following documents:
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Genome-wide association studies in pharmacogenomics: successes and lessons.

Pharmacogenetics And Genomics
AA Motsinger-Reif, E Jorgenson, MV Relling, DL Kroetz, R Weinshilboum, NJ Cox, DM Roden
Publication Date: 2013-08

Variant appearance in text: rs4363657
PubMed Link: 20639796
Variant Present in the following documents:
  • Main text
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Rhabdomyolysis and acute kidney injury secondary to concomitant use of fluvastatin and rapamycin in a renal transplant recipient.

Nephrology, Dialysis, Transplantation : Official Publication Of The European Dialysis And Transplant Association - European Renal Association
N Basic-Jukic, P Kes, L Bubic-Filipi, Z Vranjican
Publication Date: 2010-06

Variant appearance in text: rs4363657
PubMed Link: 20332417
Variant Present in the following documents:
  • Supplemental file
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The genetics of ischaemic stroke.

Journal Of Internal Medicine
M Matarin, A Singleton, J Hardy, J Meschia
Publication Date: 2010-02

Variant appearance in text: rs4363657
PubMed Link: 20175863
Variant Present in the following documents:
  • Main text
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Pharmacogenomic insights into treatment and management of statin-induced myopathy.

Genome Medicine
BJ Peters, OH Klungel, FL Visseren, A de Boer, AH Maitland-van der Zee
Publication Date: 2009-12-29

Variant appearance in text: rs4363657
PubMed Link: 20090898
Variant Present in the following documents:
  • Main text
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The influence of SLCO1B1 (OATP1B1) gene polymorphisms on response to statin therapy.

The Pharmacogenomics Journal
SP Romaine, KM Bailey, AS Hall, AJ Balmforth
Publication Date: 2010-02

Variant appearance in text: rs4363657
PubMed Link: 19884908
Variant Present in the following documents:
  • Supplemental file
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Pharmacogenetics and stroke.

Stroke
JF Meschia
Publication Date: 2009-11

Variant appearance in text: rs4363657
PubMed Link: 19762696
Variant Present in the following documents:
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Cardiovascular pharmacogenomics and individualized drug therapy.

Nature Reviews. Cardiology
NL Pereira, RM Weinshilboum
Publication Date: 2009-10

Variant appearance in text: rs4363657
PubMed Link: 19707183
Variant Present in the following documents:
  • Main text
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Genetic architecture of type 2 diabetes: recent progress and clinical implications.

Diabetes Care
RW Grant, AF Moore, JC Florez
Publication Date: 2009-06

Variant appearance in text: rs4363657
PubMed Link: 19460916
Variant Present in the following documents:
  • Main text
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Genome-wide association meta-analysis for total serum bilirubin levels.

Human Molecular Genetics
AD Johnson, M Kavousi, AV Smith, MH Chen, A Dehghan, T Aspelund, JP Lin, CM van Duijn, TB Harris, LA Cupples, AG Uitterlinden, L Launer, A Hofman, F Rivadeneira, B Stricker, Q Yang, CJ O'Donnell, V Gudnason, JC Witteman
Publication Date: 2009-07-15

Variant appearance in text: rs4363657
PubMed Link: 19414484
Variant Present in the following documents:
  • Main text
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Alternative transcript annotations:

Transcript cDNA Protein Consequence Exon Intron
ENST00000256958.2 c.1498-1331T>C - intron_variant - 11/14
NM_006446.5 c.1498-1331T>C - intron_variant - 11/14