Publications:

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The Effect of Single Nucleotide Variations in the Transmembrane Domain of OATP1B1 on in vitro Functionality.

Pharmaceutical Research

Kiander, Wilma W; Vellonen, Kati-Sisko KS; Malinen, Melina M MM; Gynther, Mikko M; Hagström, Marja M; Bhattacharya, Madhushree M; Auriola, Seppo S; Koenderink, Jan B JB; Kidron, Heidi H

Publication Date: 2021-10

Variant appearance in text: SLCO1B1: Leu543Trp; rs72661137

PubMed Link: 34647232

Variant Present in the following documents:

• Main text
• 11095_2021_Article_3107.pdf

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SLCO1B1: Application and Limitations of Deep Mutational Scanning for Genomic Missense Variant Function.

Drug Metabolism And Disposition: The Biological Fate Of Chemicals

Zhang, Lingxin L; Sarangi, Vivekananda V; Ho, Ming-Fen MF; Moon, Irene I; Kalari, Krishna R KR; Wang, Liewei L; Weinshilboum, Richard M RM

Publication Date: 2021-05

Variant appearance in text: SLCO1B1: 1628T>G; rs72661137

PubMed Link: 33658230

Variant Present in the following documents:

• Main text
• dmd.120.000264.pdf

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Genetic variation in human drug-related genes.

Genome Medicine

Schärfe, Charlotta Pauline Irmgard CPI; Tremmel, Roman R; Schwab, Matthias M; Kohlbacher, Oliver O; Marks, Debora Susan DS

Publication Date: 2017-12-22

Variant appearance in text: rs72661137

PubMed Link: 29273096

Variant Present in the following documents:

• 13073_2017_502_MOESM2_ESM.xlsx, sheet 2

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Association between SLCO1B1 -521T>C and -388A>G polymorphisms and risk of statin-induced adverse drug reactions: A meta-analysis.

Springerplus

Jiang, Jiajia J; Tang, Qing Q; Feng, Jing J; Dai, Rong R; Wang, Yang Y; Yang, Yuan Y; Tang, Xiaojun X; Deng, Changkai C; Zeng, Huan H; Zhao, Yong Y; Zhang, Fan F

Publication Date: 2016

Variant appearance in text: SLCO1B1: 1628T>G

PubMed Link: 27606156

Variant Present in the following documents:

• 40064_2016_Article_2912.pdf

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Unique expression features of cancer-type organic anion transporting polypeptide 1B3 mRNA expression in human colon and lung cancers.

Clinical And Translational Medicine

Sun, Yuchen Y; Furihata, Tomomi T; Ishii, Seiya S; Nagai, Miki M; Harada, Manami M; Shimozato, Osamu O; Kamijo, Takehiko T; Motohashi, Shinichiro S; Yoshino, Ichiro I; Kamiichi, Atsuko A; Kobayashi, Kaoru K; Chiba, Kan K

Publication Date: 2014

Variant appearance in text: SLCO1B1: 1628T>G

PubMed Link: 25625007

Variant Present in the following documents:

• s40169-014-0037-y.pdf

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Interaction of three regiospecific amino acid residues is required for OATP1B1 gain of OATP1B3 substrate specificity.

Molecular Pharmaceutics

DeGorter, Marianne K MK; Ho, Richard H RH; Leake, Brenda F BF; Tirona, Rommel G RG; Kim, Richard B RB

Publication Date: 2012-04-02

Variant appearance in text: OATP1B1: Leu543Trp; rs72661137

PubMed Link: 22352740

Variant Present in the following documents:

• Main text

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Pharmacogenomic insights into treatment and management of statin-induced myopathy.

Genome Medicine

Peters, Bas Jm BJ; Klungel, Olaf H OH; Visseren, Frank L FL; de Boer, Anthonius A; Maitland-van der Zee, Anke-Hilse AH

Publication Date: 2009-12-29

Variant appearance in text: SLCO1B1: 1628T>G

PubMed Link: 20090898

Variant Present in the following documents:

• gm120.pdf

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Role of transmembrane domain 10 for the function of organic anion transporting polypeptide 1B1.

Protein Science : A Publication Of The Protein Society

Gui, Chunshan C; Hagenbuch, Bruno B

Publication Date: 2009-11

Variant appearance in text: OATP1B1: L543W

PubMed Link: 19760661

Variant Present in the following documents:

• Main text

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Amino acid residues in transmembrane domain 10 of organic anion transporting polypeptide 1B3 are critical for cholecystokinin octapeptide transport.

Biochemistry

Gui, Chunshan C; Hagenbuch, Bruno B

Publication Date: 2008-09-02

Variant appearance in text: OATP1B1: L543W

PubMed Link: 18690707

Variant Present in the following documents:

• Main text

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