Publications:

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Pharmacogenetics of tenofovir renal toxicity in HIV-positive Southern Africans.

Pharmacogenetics And Genomics

Mateza, Somila S; Bradford, Yuki Y; Maartens, Gary G; Sokhela, Simiso S; Chandiwana, Nomathemba C NC; Venter, Willem D F WDF; Post, Frank A FA; Ritchie, Marylyn D MD; Haas, David W DW; Sinxadi, Phumla P

Publication Date: 2023-04-24

Variant appearance in text: rs11045879

PubMed Link: 37099271

Variant Present in the following documents:

• Main text
• pgen-33-91.pdf

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Pharmacogenomic profile of a central European urban random population-Czech population.

Plos One

Proietti, Riccardo R; Maranho Neto, Geraldo A GA; Kunzova, Sarka S; Lo Re, Oriana O; Ahola-Olli, Ari A; Heliste, Juho J; Gonzalez-Rivas, Juan Pablo JP; Vinciguerra, Manlio M

Publication Date: 2023

Variant appearance in text: rs11045879

PubMed Link: 37079615

Variant Present in the following documents:

• Main text
• pone.0284386.pdf

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Personalized Medicine in Infant Population with Cancer: Pharmacogenetic Pilot Study of Polymorphisms Related to Toxicity and Response to Chemotherapy.

Cancers

Urtasun, Andrea A; Olivera, Gladys G GG; Sendra, Luis L; Aliño, Salvador F SF; Berlanga, Pablo P; Gargallo, Pablo P; Hervás, David D; Balaguer, Julia J; Juan-Ribelles, Antonio A; Andrés, María Del Mar MDM; Cañete, Adela A; Herrero, María José MJ

Publication Date: 2023-02-23

Variant appearance in text: rs11045879

PubMed Link: 36900216

Variant Present in the following documents:

• cancers-15-01424.pdf

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Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics

Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P

Publication Date: 2023-02-23

Variant appearance in text: SLCO1B1: 1865+4846T>C

PubMed Link: 36823319

Variant Present in the following documents:

• 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6

View BVdb publication page

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Effects of genetic polymorphisms on methotrexate levels and toxicity in Chinese patients with acute lymphoblastic leukemia.

Blood Science (Baltimore, Md.)

Hao, Qishan Q; Song, Yang Y; Fang, Qiuyun Q; Lin, Yani Y; Chen, Long L; Wang, Xiaodan X; Zhang, Ping P; Wang, Zhe Z; Gong, Xiaoyuan X; Liu, Kaiqi K; Li, Qinghua Q; Tian, Zheng Z; Wang, Min M; Wang, Jianxiang J; Mi, Yingchang Y

Publication Date: 2023-01

Variant appearance in text: rs11045879

PubMed Link: 36742186

Variant Present in the following documents:

• Main text
• bs9-5-32.pdf

View BVdb publication page

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Association between high-dose methotrexate-induced toxicity and polymorphisms within methotrexate pathway genes in acute lymphoblastic leukemia.

Frontiers In Pharmacology

Xu, Meng M; Wu, Shuangshuang S; Wang, Yue Y; Zhao, Yundong Y; Wang, Ximin X; Wei, Changhong C; Liu, Xueying X; Hao, Feng F; Hu, Cheng C

Publication Date: 2022

Variant appearance in text: rs11045879

PubMed Link: 36532750

Variant Present in the following documents:

• Main text
• fphar-13-1003812.pdf

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The Role of Single Nucleotide Polymorphisms in Transporter Proteins and the Folate Metabolism Pathway in Delayed Methotrexate Excretion: A Case Report and Literature Review.

Pharmacogenomics And Personalized Medicine

Wang, Jun J; Zhao, Yue-Tao YT; Sun, Meng-Jiao MJ; Chen, Feng F; Guo, Hong-Li HL

Publication Date: 2022

Variant appearance in text: rs11045879

PubMed Link: 36349164

Variant Present in the following documents:

• Main text
• pgpm-15-919.pdf

View BVdb publication page

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Role of Drug Transporters in Elucidating Inter-Individual Variability in Pediatric Chemotherapy-Related Toxicities and Response.

Pharmaceuticals (Basel, Switzerland)

Kamath, Ashwin A; Srinivasamurthy, Suresh Kumar SK; Chowta, Mukta N MN; Ullal, Sheetal D SD; Daali, Youssef Y; Chakradhara Rao, Uppugunduri S US

Publication Date: 2022-08-11

Variant appearance in text: rs11045879

PubMed Link: 36015138

Variant Present in the following documents:

• Main text
• pharmaceuticals-15-00990.pdf

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Pharmacogenetics and Pain Treatment with a Focus on Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) and Antidepressants: A Systematic Review.

Pharmaceutics

Zobdeh, Farzin F; Eremenko, Ivan I II; Akan, Mikail A MA; Tarasov, Vadim V VV; Chubarev, Vladimir N VN; Schiöth, Helgi B HB; Mwinyi, Jessica J

Publication Date: 2022-06-01

Variant appearance in text: rs11045879

PubMed Link: 35745763

Variant Present in the following documents:

• Main text
• pharmaceutics-14-01190.pdf

View BVdb publication page

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Pharmacogenetics implementation in the clinics: information and guidelines for germline variants.

Cancer Drug Resistance (Alhambra, Calif.)

Olivera, Gladys G; Sendra, Luis L; Herrero, María José MJ; Berlanga, Pablo P; Gargallo, Pablo P; Yáñez, Yania Y; Urtasun, Andrea A; de Mora, Jaime Font JF; Castel, Victoria V; Cañete, Adela A; Aliño, Salvador F SF

Publication Date: 2019

Variant appearance in text: rs11045879

PubMed Link: 35582138

Variant Present in the following documents:

• cdr-2-53.pdf

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Pharmacogenetics of Dolutegravir Plasma Exposure Among Southern Africans With Human Immunodeficiency Virus.

The Journal Of Infectious Diseases

Cindi, Zinhle Z; Kawuma, Aida N AN; Maartens, Gary G; Bradford, Yuki Y; Venter, Francois F; Sokhela, Simiso S; Chandiwana, Nomathemba N; Wasmann, Roeland E RE; Denti, Paolo P; Wiesner, Lubbe L; Ritchie, Marylyn D MD; Haas, David W DW; Sinxadi, Phumla P

Publication Date: 2022-11-01

Variant appearance in text: rs11045879

PubMed Link: 35512135

Variant Present in the following documents:

• EMS145648-supplement-Supplementary_file.pdf

View BVdb publication page

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Effects of Cytochrome P450 and Transporter Polymorphisms on the Bioavailability and Safety of Dutasteride and Tamsulosin.

Frontiers In Pharmacology

Villapalos-García, Gonzalo G; Zubiaur, Pablo P; Navares-Gómez, Marcos M; Saiz-Rodríguez, Miriam M; Mejía-Abril, Gina G; Martín-Vílchez, Samuel S; Román, Manuel M; Ochoa, Dolores D; Abad-Santos, Francisco F

Publication Date: 2021

Variant appearance in text: rs11045879

PubMed Link: 34690761

Variant Present in the following documents:

• Main text

View BVdb publication page

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Integrated CGH/WES Analyses Advance Understanding of Aggressive Neuroblastoma Evolution: A Case Study.

Cells

Corallo, Diana D; Zanon, Carlo C; Pantile, Marcella M; Tonini, Gian Paolo GP; Zin, Angelica A; Francescato, Samuela S; Rossi, Bartolomeo B; Trevisson, Eva E; Pinato, Claudia C; Monferrer, Ezequiel E; Noguera, Rosa R; Aliño, Salvador F SF; Herrero, Maria Jose MJ; Biffi, Alessandra A; Viscardi, Elisabetta E; Aveic, Sanja S

Publication Date: 2021-10-09

Variant appearance in text: rs11045879

PubMed Link: 34685674

Variant Present in the following documents:

• Main text

View BVdb publication page

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Variants in COMT, CYP3A5, CYP2B6, and ABCG2 Alter Quetiapine Pharmacokinetics.

Pharmaceutics

Zubiaur, Pablo P; Fernández-Campos, Paula P; Navares-Gómez, Marcos M; Soria-Chacartegui, Paula P; Villapalos-García, Gonzalo G; Román, Manuel M; Mejía-Abril, Gina G; Ochoa, Dolores D; Abad-Santos, Francisco F

Publication Date: 2021-09-28

Variant appearance in text: rs11045879

PubMed Link: 34683865

Variant Present in the following documents:

• Main text

View BVdb publication page

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A Risk Scoring Model for High-Dose Methotrexate-Induced Liver Injury in Children With Acute Lymphoblastic Leukemia Based on Gene Polymorphism Study.

Frontiers In Pharmacology

He, Xia X; Yao, Pingli P; Li, Mengting M; Liang, Hong H; Liu, Yilong Y; Du, Shan S; Zhang, Min M; Sun, Wenzhuo W; Wang, Zeyuan Z; Hao, Xin X; Yu, Ze Z; Gao, Fei F; Liu, Xinxia X; Tong, Rongsheng R

Publication Date: 2021

Variant appearance in text: rs11045879

PubMed Link: 34658865

Variant Present in the following documents:

• Main text
• fphar-12-726229.pdf

View BVdb publication page

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Genetic Polymorphisms of GGH and ABCC2 Are Associated with Methotrexate Intolerance in Patients with Rheumatoid Arthritis.

Journal Of Clinical Medicine

Escudero-Contreras, Alejandro A; López-Medina, Clementina C; Collantes-Estévez, Eduardo E; Ortega-Castro, Rafaela R; Calvo-Gutiérrez, Jerusalem J; Mena-Vázquez, Natalia N; Panero-Lamothe, Blanca B; Manzanares-Martín, Bárbara B; Cáliz-Cáliz, Rafael R; Jiménez-Morales, Alberto A; Ruiz-Jiménez, Mayte M; Font-Ugalde, Pilar P

Publication Date: 2021-09-09

Variant appearance in text: rs11045879

PubMed Link: 34575187

Variant Present in the following documents:

• Main text
• jcm-10-04070.pdf

View BVdb publication page

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PriME-PGx: La Princesa University Hospital Multidisciplinary Initiative for the Implementation of Pharmacogenetics.

Journal Of Clinical Medicine

Zubiaur, Pablo P; Mejía-Abril, Gina G; Navares-Gómez, Marcos M; Villapalos-García, Gonzalo G; Soria-Chacartegui, Paula P; Saiz-Rodríguez, Miriam M; Ochoa, Dolores D; Abad-Santos, Francisco F

Publication Date: 2021-08-24

Variant appearance in text: rs11045879

PubMed Link: 34501219

Variant Present in the following documents:

• Main text
• jcm-10-03772.pdf

View BVdb publication page

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Systematic Review of Pharmacogenetic Factors That Influence High-Dose Methotrexate Pharmacokinetics in Pediatric Malignancies.

Cancers

Taylor, Zachary L ZL; Vang, Jesper J; Lopez-Lopez, Elixabet E; Oosterom, Natanja N; Mikkelsen, Torben T; Ramsey, Laura B LB

Publication Date: 2021-06-07

Variant appearance in text: rs11045879

PubMed Link: 34200242

Variant Present in the following documents:

• Main text
• cancers-13-02837.pdf

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Dexketoprofen Pharmacokinetics is not Significantly Altered by Genetic Polymorphism.

Frontiers In Pharmacology

Mejía-Abril, Gina G; Zubiaur, Pablo P; Navares-Gómez, Marcos M; Villapalos-García, Gonzalo G; Román, Manuel M; Ochoa, Dolores D; Abad-Santos, Francisco F

Publication Date: 2021

Variant appearance in text: rs11045879

PubMed Link: 33995083

Variant Present in the following documents:

• Main text
• fphar-12-660639.pdf

View BVdb publication page

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SLCO1B1 Phenotype and CYP3A5 Polymorphism Significantly Affect Atorvastatin Bioavailability.

Journal Of Personalized Medicine

Zubiaur, Pablo P; Benedicto, Maria Dolores MD; Villapalos-García, Gonzalo G; Navares-Gómez, Marcos M; Mejía-Abril, Gina G; Román, Manuel M; Martín-Vílchez, Samuel S; Ochoa, Dolores D; Abad-Santos, Francisco F

Publication Date: 2021-03-13

Variant appearance in text: rs11045879

PubMed Link: 33805706

Variant Present in the following documents:

• Main text

View BVdb publication page

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Study on Relationships of Tumor Status and Gene Polymorphism With Blood Concentration of MTX and Toxicities in 63 Pediatric Mature B Cell Lymphoma in Chinese Population.

Technology In Cancer Research & Treatment

Huang, Shuang S; Jin, Lin L; Yang, Jing J; Duan, Long Yan LY; Zhang, Meng M; Zhou, Ju Chun JC; Zhang, Hong Yong HY

Publication Date: 2021

Variant appearance in text: rs11045879

PubMed Link: 33752528

Variant Present in the following documents:

• Main text
• 10.1177_1533033821995288.pdf

View BVdb publication page

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Phenotype prediction and characterization of 25 pharmacogenes in Thais from whole genome sequencing for clinical implementation.

Scientific Reports

Mauleekoonphairoj, John J; Chamnanphon, Monpat M; Khongphatthanayothin, Apichai A; Sutjaporn, Boosamas B; Wandee, Pharawee P; Poovorawan, Yong Y; Nademanee, Koonlawee K; Pongpanich, Monnat M; Chariyavilaskul, Pajaree P

Publication Date: 2020-11-03

Variant appearance in text: rs11045879

PubMed Link: 33144648

Variant Present in the following documents:

• Main text
• 41598_2020_Article_76085.pdf

View BVdb publication page

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Analysis of Drug Metabolizing Gene Panel in Osteosarcoma Patients Identifies Association Between Variants in SULT1E1, CYP2B6 and CYP4F8 and Methotrexate Levels and Toxicities.

Frontiers In Pharmacology

Hurkmans, Evelien G E EGE; Klumpers, Marije J MJ; Vermeulen, Sita H SH; Hagleitner, Melanie M MM; Flucke, Uta U; Schreuder, H W Bart HWB; Gelderblom, Hans H; Bras, Johannes J; Guchelaar, Henk-Jan HJ; Coenen, Marieke J H MJH; Te Loo, D Maroeska W M DMWM

Publication Date: 2020

Variant appearance in text: rs11045879

PubMed Link: 32903464

Variant Present in the following documents:

• Main text
• fphar-11-01241.pdf

View BVdb publication page

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Pharmacogenomics as a Tool to Limit Acute and Long-Term Adverse Effects of Chemotherapeutics: An Update in Pediatric Oncology.

Frontiers In Pharmacology

Bernsen, Emma C EC; Hagleitner, Melanie M MM; Kouwenberg, Theodorus W TW; Hanff, Lidwien M LM

Publication Date: 2020

Variant appearance in text: rs11045879

PubMed Link: 32848787

Variant Present in the following documents:

• Table_1.pdf

View BVdb publication page

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Implementation of Pharmacogenetics to Individualize Treatment Regimens for Children with Acute Lymphoblastic Leukemia.

Pharmacogenomics And Personalized Medicine

Maamari, Dimitri D; El-Khoury, Habib H; Saifi, Omran O; Muwakkit, Samar A SA; Zgheib, Nathalie K NK

Publication Date: 2020

Variant appearance in text: rs11045879

PubMed Link: 32848445

Variant Present in the following documents:

• Main text

View BVdb publication page

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Pharmacogenomics and Pharmacogenetics in Osteosarcoma: Translational Studies and Clinical Impact.

International Journal Of Molecular Sciences

Hattinger, Claudia Maria CM; Patrizio, Maria Pia MP; Luppi, Silvia S; Serra, Massimo M

Publication Date: 2020-06-30

Variant appearance in text: rs11045879

PubMed Link: 32629971

Variant Present in the following documents:

• Main text
• ijms-21-04659.pdf

View BVdb publication page

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Drug Resistance Biomarkers and Their Clinical Applications in Childhood Acute Lymphoblastic Leukemia.

Frontiers In Oncology

Aberuyi, Narges N; Rahgozar, Soheila S; Ghodousi, Elaheh Sadat ES; Ghaedi, Kamran K

Publication Date: 2019

Variant appearance in text: rs11045879

PubMed Link: 32010613

Variant Present in the following documents:

• Main text

View BVdb publication page

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Heterogeneity in the distribution of 159 drug-response related SNPs in world populations and their genetic relatedness.

Plos One

Ahsan, Tamim T; Urmi, Nusrat Jahan NJ; Sajib, Abu Ashfaqur AA

Publication Date: 2020

Variant appearance in text: rs11045879

PubMed Link: 31971968

Variant Present in the following documents:

• Main text
• pone.0228000.pdf

View BVdb publication page

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Introducing the first whole genomes of nationals from the United Arab Emirates.

Scientific Reports

AlSafar, Habiba S HS; Al-Ali, Mariam M; Elbait, Gihan Daw GD; Al-Maini, Mustafa H MH; Ruta, Dymitr D; Peramo, Braulio B; Henschel, Andreas A; Tay, Guan K GK

Publication Date: 2019-10-11

Variant appearance in text: rs11045879

PubMed Link: 31604968

Variant Present in the following documents:

• 41598_2019_50876_MOESM1_ESM.xlsx, sheet 1
• 41598_2019_50876_MOESM1_ESM.xlsx, sheet 2

View BVdb publication page

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Pathway genes and metabolites in thiopurine therapy in Korean children with acute lymphoblastic leukaemia.

British Journal Of Clinical Pharmacology

Choi, Rihwa R; Sohn, Insuk I; Kim, Min-Ji MJ; Woo, Hye In HI; Lee, Ji Won JW; Ma, Youngeun Y; Yi, Eun Sang ES; Koo, Hong Hoe HH; Lee, Soo-Youn SY

Publication Date: 2019-07

Variant appearance in text: rs11045879

PubMed Link: 30927276

Variant Present in the following documents:

• Main text

View BVdb publication page

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Pharmacogenomic and Pharmacotranscriptomic Profiling of Childhood Acute Lymphoblastic Leukemia: Paving the Way to Personalized Treatment.

Genes

Pavlovic, Sonja S; Kotur, Nikola N; Stankovic, Biljana B; Zukic, Branka B; Gasic, Vladimir V; Dokmanovic, Lidija L

Publication Date: 2019-03-01

Variant appearance in text: rs11045879

PubMed Link: 30832275

Variant Present in the following documents:

• Main text
• genes-10-00191.pdf

View BVdb publication page

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Organic Anion Transporting Polypeptides: Emerging Roles in Cancer Pharmacology.

Molecular Pharmacology

Schulte, Rachael R RR; Ho, Richard H RH

Publication Date: 2019-05

Variant appearance in text: SLCO1B1: 1865+4846T>C; rs11045879

PubMed Link: 30782852

Variant Present in the following documents:

• Main text

View BVdb publication page

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Whole genome sequencing identifies high-impact variants in well-known pharmacogenomic genes.

The Pharmacogenomics Journal

Choi, Jihoon J; Tantisira, Kelan G KG; Duan, Qing Ling QL

Publication Date: 2019-04

Variant appearance in text: rs11045879

PubMed Link: 30214008

Variant Present in the following documents:

• NIHMS1503453-supplement-3.xlsx, sheet 1

View BVdb publication page

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Induction and Amelioration of Methotrexate-Induced Gastrointestinal Toxicity are Related to Immune Response and Gut Microbiota.

Ebiomedicine

Zhou, Bailing B; Xia, Xuyang X; Wang, Peiqi P; Chen, Shuang S; Yu, Chaoheng C; Huang, Rong R; Zhang, Rui R; Wang, Yantai Y; Lu, Lian L; Yuan, Fengjiao F; Tian, Yaomei Y; Fan, Yingzi Y; Zhang, Xueyan X; Shu, Yang Y; Zhang, Shouyue S; Bai, Ding D; Wu, Lei L; Xu, Heng H; Yang, Li L

Publication Date: 2018-07

Variant appearance in text: rs11045879

PubMed Link: 30049384

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

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Clinical Pharmacogenetic Models of Treatment Response to Methotrexate Monotherapy in Slovenian and Serbian Rheumatoid Arthritis Patients: Differences in Patient's Management May Preclude Generalization of the Models.

Frontiers In Pharmacology

Jenko, Barbara B; Tomšič, Matija M; Jekić, Biljana B; Milić, Vera V; Dolžan, Vita V; Praprotnik, Sonja S

Publication Date: 2018

Variant appearance in text: SLCO1B1: 1865+4846T>C; rs11045879

PubMed Link: 29422864

Variant Present in the following documents:

• Main text

View BVdb publication page

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Association between SLC19A1 Gene Polymorphism and High Dose Methotrexate Toxicity in Childhood Acute Lymphoblastic Leukaemia and Non Hodgkin Malignant Lymphoma: Introducing a Haplotype based Approach.

Radiology And Oncology

Kotnik, Barbara Faganel BF; Jazbec, Janez J; Grabar, Petra Bohanec PB; Rodriguez-Antona, Cristina C; Dolzan, Vita V

Publication Date: 2017-12

Variant appearance in text: rs11045879

PubMed Link: 29333125

Variant Present in the following documents:

• Main text
• raon-51-455.pdf

View BVdb publication page

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APEX1 Polymorphism and Mercaptopurine-Related Early Onset Neutropenia in Pediatric Acute Lymphoblastic Leukemia.

Cancer Research And Treatment

Kim, Hyery H; Seo, Heewon H; Park, Yoomi Y; Min, Byung-Joo BJ; Seo, Myung-Eui ME; Park, Kyung Duk KD; Shin, Hee Young HY; Kim, Ju Han JH; Kang, Hyoung Jin HJ

Publication Date: 2018-07

Variant appearance in text: rs11045879

PubMed Link: 28882023

Variant Present in the following documents:

• Main text
• crt-2017-351.pdf

View BVdb publication page

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Polymorphisms in methotrexate transporters and their relationship to plasma methotrexate levels, toxicity of high-dose methotrexate, and outcome of pediatric acute lymphoblastic leukemia.

Oncotarget

Liu, Shu-Guang SG; Gao, Chao C; Zhang, Rui-Dong RD; Zhao, Xiao-Xi XX; Cui, Lei L; Li, Wei-Jing WJ; Chen, Zhen-Ping ZP; Yue, Zhi-Xia ZX; Zhang, Yuan-Yuan YY; Wu, Min-Yuan MY; Wang, Jian-Xiang JX; Li, Zhi-Gang ZG; Zheng, Hu-Yong HY

Publication Date: 2017-06-06

Variant appearance in text: rs11045879

PubMed Link: 28525903

Variant Present in the following documents:

• Main text
• oncotarget-08-37761.pdf

View BVdb publication page

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Molecular pathways associated with blood pressure and hexadecanedioate levels.

Plos One

Menni, Cristina C; Metrustry, Sarah J SJ; Ehret, Georg G; Dominiczak, Anna F AF; Chowienczyk, Phil P; Spector, Tim D TD; Padmanabhan, Sandosh S; Valdes, Ana M AM

Publication Date: 2017

Variant appearance in text: rs11045879

PubMed Link: 28403188

Variant Present in the following documents:

• Main text

View BVdb publication page

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MTHFR polymorphisms in childhood acute lymphoblastic leukemia: influence on methotrexate therapy.

Pharmacogenomics And Personalized Medicine

Umerez, Maitane M; Gutierrez-Camino, Ángela Á; Muñoz-Maldonado, Carmen C; Martin-Guerrero, Idoia I; Garcia-Orad, Africa A

Publication Date: 2017

Variant appearance in text: rs11045879

PubMed Link: 28392709

Variant Present in the following documents:

• Main text
• pgpm-10-069.pdf

View BVdb publication page

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