Analysis of CACNA1C and KCNH2 Risk Variants on Cardiac Autonomic Function in Patients with Schizophrenia.
Genes
Refisch, Alexander A; Komatsuzaki, Shoko S; Ungelenk, Martin M; Schumann, Andy A; Chung, Ha-Yeun HY; Schilling, Susann S SS; Jantzen, Wibke W; Schröder, Sabine S; Nöthen, Markus M MM; Mühleisen, Thomas W TW; Hübner, Christian A CA; Bär, Karl-Jürgen KJ
A systematic review of common genetic variation and biological pathways in autism spectrum disorder.
Bmc Neuroscience
Rodriguez-Gomez, Diego Alejandro DA; Garcia-Guaqueta, Danna Paola DP; Charry-Sánchez, Jesús David JD; Sarquis-Buitrago, Elias E; Blanco, Mariana M; Velez-van-Meerbeke, Alberto A; Talero-Gutiérrez, Claudia C
Parallel functional testing identifies enhancers active in early postnatal mouse brain.
Elife
Lambert, Jason T JT; Su-Feher, Linda L; Cichewicz, Karol K; Warren, Tracy L TL; Zdilar, Iva I; Wang, Yurong Y; Lim, Kenneth J KJ; Haigh, Jessica L JL; Morse, Sarah J SJ; Canales, Cesar P CP; Stradleigh, Tyler W TW; Castillo Palacios, Erika E; Haghani, Viktoria V; Moss, Spencer D SD; Parolini, Hannah H; Quintero, Diana D; Shrestha, Diwash D; Vogt, Daniel D; Byrne, Leah C LC; Nord, Alex S AS
Association Study of Sequence Variants in Voltage-gated Ca2+ Channel Subunit Alpha-1C and Autism Spectrum Disorders.
Reports Of Biochemistry & Molecular Biology
Sayad, Arezou A; Ghafouri-Fard, Soudeh S; Noroozi, Rezvan R; Omrani, Mir Davood MD; Ganji, Maziar M; Dastmalchi, Romina R; Glassy, Mark M; Taheri, Mohammad M
Genome-Wide Supported Risk Variants in MIR137, CACNA1C, CSMD1, DRD2, and GRM3 Contribute to Schizophrenia Susceptibility in Pakistani Population.
Psychiatry Investigation
Fatima, Ambrin A; Farooq, Muhammad M; Abdullah, Uzma U; Tariq, Muhammad M; Mustafa, Tanveer T; Iqbal, Muhammad M; Tommerup, Niels N; Mahmood Baig, Shahid S
Cognitive Characterization of Schizophrenia Risk Variants Involved in Synaptic Transmission: Evidence of CACNA1C's Role in Working Memory.
Neuropsychopharmacology : Official Publication Of The American College Of Neuropsychopharmacology
Cosgrove, Donna D; Mothersill, Omar O; Kendall, Kimberley K; Konte, Bettina B; Harold, Denise D; Giegling, Ina I; Hartmann, Annette A; Richards, Alex A; Mantripragada, Kiran K; , ; Owen, Michael J MJ; O'Donovan, Michael C MC; Gill, Michael M; Rujescu, Dan D; Walters, James J; Corvin, Aiden A; Morris, Derek W DW; Donohoe, Gary G
CACNA1C hypermethylation is associated with bipolar disorder.
Translational Psychiatry
Starnawska, A A; Demontis, D D; Pen, A A; Hedemand, A A; Nielsen, A L AL; Staunstrup, N H NH; Grove, J J; Als, T D TD; Jarram, A A; O'Brien, N L NL; Mors, O O; McQuillin, A A; Børglum, A D AD; Nyegaard, M M
Roussos, Panos P; Mitchell, Amanda C AC; Voloudakis, Georgios G; Fullard, John F JF; Pothula, Venu M VM; Tsang, Jonathan J; Stahl, Eli A EA; Georgakopoulos, Anastasios A; Ruderfer, Douglas M DM; Charney, Alexander A; Okada, Yukinori Y; Siminovitch, Katherine A KA; Worthington, Jane J; Padyukov, Leonid L; Klareskog, Lars L; Gregersen, Peter K PK; Plenge, Robert M RM; Raychaudhuri, Soumya S; Fromer, Menachem M; Purcell, Shaun M SM; Brennand, Kristen J KJ; Robakis, Nikolaos K NK; Schadt, Eric E EE; Akbarian, Schahram S; Sklar, Pamela P
Calcium-dependent intracellular signal pathways in primary cultured adipocytes and ANK3 gene variation in patients with bipolar disorder and healthy controls.
Molecular Psychiatry
Hayashi, A A; Le Gal, K K; Södersten, K K; Vizlin-Hodzic, D D; Ågren, H H; Funa, K K
Are genetic risk factors for psychosis also associated with dimension-specific psychotic experiences in adolescence?
Plos One
Sieradzka, Dominika D; Power, Robert A RA; Freeman, Daniel D; Cardno, Alastair G AG; McGuire, Philip P; Plomin, Robert R; Meaburn, Emma L EL; Dudbridge, Frank F; Ronald, Angelica A
Neurophysiologic effect of GWAS derived schizophrenia and bipolar risk variants.
American Journal Of Medical Genetics. Part B, Neuropsychiatric Genetics : The Official Publication Of The International Society Of Psychiatric Genetics
Hall, Mei-Hua MH; Levy, Deborah L DL; Salisbury, Dean F DF; Haddad, Steve S; Gallagher, Patience P; Lohan, Mary M; Cohen, Bruce B; Ongür, Dost D; Smoller, Jordan W JW
A population-based study of genetic variation and psychotic experiences in adolescents.
Schizophrenia Bulletin
Zammit, Stanley S; Hamshere, Marian M; Dwyer, Sarah S; Georgiva, Lyudmila L; Timpson, Nic N; Moskvina, Valentina V; Richards, Alexander A; Evans, David M DM; Lewis, Glyn G; Jones, Peter P; Owen, Michael J MJ; O'Donovan, Michael C MC
Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate.
Plos Genetics
Andreassen, Ole A OA; Thompson, Wesley K WK; Schork, Andrew J AJ; Ripke, Stephan S; Mattingsdal, Morten M; Kelsoe, John R JR; Kendler, Kenneth S KS; O'Donovan, Michael C MC; Rujescu, Dan D; Werge, Thomas T; Sklar, Pamela P; , ; , ; Roddey, J Cooper JC; Chen, Chi-Hua CH; McEvoy, Linda L; Desikan, Rahul S RS; Djurovic, Srdjan S; Dale, Anders M AM
Suggestive evidence for association between L-type voltage-gated calcium channel (CACNA1C) gene haplotypes and bipolar disorder in Latinos: a family-based association study.
Bipolar Disorders
Gonzalez, Suzanne S; Xu, Chun C; Ramirez, Mercedes M; Zavala, Juan J; Armas, Regina R; Contreras, Salvador A SA; Contreras, Javier J; Dassori, Albana A; Leach, Robin J RJ; Flores, Deborah D; Jerez, Alvaro A; Raventós, Henriette H; Ontiveros, Alfonso A; Nicolini, Humberto H; Escamilla, Michael M
Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors.
American Journal Of Human Genetics
Andreassen, Ole A OA; Djurovic, Srdjan S; Thompson, Wesley K WK; Schork, Andrew J AJ; Kendler, Kenneth S KS; O'Donovan, Michael C MC; Rujescu, Dan D; Werge, Thomas T; van de Bunt, Martijn M; Morris, Andrew P AP; McCarthy, Mark I MI; , ; , ; , ; Roddey, J Cooper JC; McEvoy, Linda K LK; Desikan, Rahul S RS; Dale, Anders M AM
Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC.
Molecular Psychiatry
Hamshere, M L ML; Walters, J T R JT; Smith, R R; Richards, A L AL; Green, E E; Grozeva, D D; Jones, I I; Forty, L L; Jones, L L; Gordon-Smith, K K; Riley, B B; O'Neill, F A FA; O'Neill, T T; Kendler, K S KS; Sklar, P P; Purcell, S S; Kranz, J J; , ; , ; , ; Morris, D D; Gill, M M; Holmans, P P; Craddock, N N; Corvin, A A; Owen, M J MJ; O'Donovan, M C MC
Mood disorder susceptibility gene CACNA1C modifies mood-related behaviors in mice and interacts with sex to influence behavior in mice and diagnosis in humans.
Biological Psychiatry
Dao, David T DT; Mahon, Pamela Belmonte PB; Cai, Xiang X; Kovacsics, Colleen E CE; Blackwell, Robert A RA; Arad, Michal M; Shi, Jianxin J; Zandi, Peter P PP; O'Donnell, Patricio P; , ; Knowles, James A JA; Weissman, Myrna M MM; Coryell, William W; Scheftner, William A WA; Lawson, William B WB; Levinson, Douglas F DF; Thompson, Scott M SM; Potash, James B JB; Gould, Todd D TD