KRAS c.437C>G ;(p.A146G)

Variant ID: 12-25378561-G-C

NM_004985.3(KRAS):c.437C>G;(p.A146G)

This variant was identified in 8 publications

View GRCh38 version.




Publications:


Identification of relevant genetic alterations in cancer using topological data analysis.

Nature Communications
Rabadán, Raúl R; Mohamedi, Yamina Y; Rubin, Udi U; Chu, Tim T; Alghalith, Adam N AN; Elliott, Oliver O; Arnés, Luis L; Cal, Santiago S; Obaya, Álvaro J ÁJ; Levine, Arnold J AJ; Cámara, Pablo G PG
Publication Date: 2020-07-30

Variant appearance in text: KRAS: A146G
PubMed Link: 32732999
Variant Present in the following documents:
  • 41467_2020_17659_MOESM3_ESM.xls, sheet 1
View BVdb publication page



Tumor Location Is Associated With the Prevalence of Braf And Pik3ca Mutations in Patients with Wild-Type Ras Colorectal Cancer: A Prospective Multi-Center Cohort Study in Japan.

Translational Oncology
Taniguchi, Hiroya H; Uehara, Keisuke K; Nakayama, Goro G; Nakayama, Hiroshi H; Aiba, Toshisada T; Hattori, Norifumi N; Kataoka, Masato M; Nakano, Yasuyuki Y; Kawase, Yoshihisa Y; Okochi, Osamu O; Matsuoka, Hiroshi H; Utsunomiya, Setsuo S; Sakamoto, Eiji E; Mori, Yoshinori Y; Umeda, Shinichi S; Shikano, Toshio T; Komori, Koji K; Tajika, Masahiro M; Kadowaki, Shigenori S; Muro, Kei K; Yatabe, Yasushi Y
Publication Date: 2020-07

Variant appearance in text: KRAS: A146G
PubMed Link: 32428838
Variant Present in the following documents:
  • Main text
View BVdb publication page



Validation and Clinical Applications of a Comprehensive Next Generation Sequencing System for Molecular Characterization of Solid Cancer Tissues.

Frontiers In Molecular Biosciences
Dehghani, Mehdi M; Rosenblatt, Kevin P KP; Li, Lei L; Rakhade, Mrudula M; Amato, Robert J RJ
Publication Date: 2019

Variant appearance in text: KRAS: A146G
PubMed Link: 31681791
Variant Present in the following documents:
  • Data_Sheet_9.xlsx, sheet 1
View BVdb publication page



Clinicopathological features and endoscopic characteristics of inverted sessile serrated adenomas/polyps.

Endoscopy International Open
Takashima, Kenji K; Oono, Yasuhiro Y; Kojima, Motohiro M; Ikematsu, Hiroaki H; Akimoto, Tetsuo T; Yano, Tomonori T
Publication Date: 2019-03

Variant appearance in text: KRAS: A146G
PubMed Link: 30834291
Variant Present in the following documents:
  • Main text
  • 10-1055-a-0820-2179.pdf
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Phase II trial of biweekly cetuximab and irinotecan as third-line therapy for pretreated KRAS exon 2 wild-type colorectal cancer.

Cancer Science
Osumi, Hiroki H; Shinozaki, Eiji E; Mashima, Tetsuo T; Wakatsuki, Takeru T; Suenaga, Mitsukuni M; Ichimura, Takashi T; Ogura, Mariko M; Ota, Yumiko Y; Nakayama, Izuma I; Takahari, Daisuke D; Chin, Keisho K; Miki, Yoshio Y; Yamaguchi, Kensei K
Publication Date: 2018-08

Variant appearance in text: KRAS: A146G
PubMed Link: 29908105
Variant Present in the following documents:
  • Main text
  • CAS-109-2567.pdf
View BVdb publication page



A retrospective observational study of clinicopathological features of KRAS, NRAS, BRAF and PIK3CA mutations in Japanese patients with metastatic colorectal cancer.

Bmc Cancer
Kawazoe, Akihito A; Shitara, Kohei K; Fukuoka, Shota S; Kuboki, Yasutoshi Y; Bando, Hideaki H; Okamoto, Wataru W; Kojima, Takashi T; Fuse, Nozomu N; Yamanaka, Takeharu T; Doi, Toshihiko T; Ohtsu, Atsushi A; Yoshino, Takayuki T
Publication Date: 2015-04-11

Variant appearance in text: KRAS: A146G
PubMed Link: 25886136
Variant Present in the following documents:
  • Main text
  • 12885_2015_Article_1276.pdf
View BVdb publication page



GNAS and KRAS Mutations Define Separate Progression Pathways in Intraductal Papillary Mucinous Neoplasm-Associated Carcinoma.

Journal Of The American College Of Surgeons
Tan, Marcus C MC; Basturk, Olca O; Brannon, A Rose AR; Bhanot, Umesh U; Scott, Sasinya N SN; Bouvier, Nancy N; LaFemina, Jennifer J; Jarnagin, William R WR; Berger, Michael F MF; Klimstra, David D; Allen, Peter J PJ
Publication Date: 2015-05

Variant appearance in text: KRAS: A146G
PubMed Link: 25840541
Variant Present in the following documents:
  • Main text
View BVdb publication page



Simultaneous identification of 36 mutations in KRAS codons 61 and 146, BRAF, NRAS, and PIK3CA in a single reaction by multiplex assay kit.

Bmc Cancer
Bando, Hideaki H; Yoshino, Takayuki T; Shinozaki, Eiji E; Nishina, Tomohiro T; Yamazaki, Kentaro K; Yamaguchi, Kensei K; Yuki, Satoshi S; Kajiura, Shinya S; Fujii, Satoshi S; Yamanaka, Takeharu T; Tsuchihara, Katsuya K; Ohtsu, Atsushi A
Publication Date: 2013-09-03

Variant appearance in text: KRAS: A146G
PubMed Link: 24006859
Variant Present in the following documents:
  • Main text
  • 1471-2407-13-405.pdf
View BVdb publication page