KRAS c.437C>A ;(p.A146E)

Variant ID: 12-25378561-G-T

NM_004985.3(KRAS):c.437C>A;(p.A146E)

This variant was identified in 7 publications

View GRCh38 version.




Publications:


Genome-wide analyses of 200,453 individuals yield new insights into the causes and consequences of clonal hematopoiesis.

Nature Genetics
Kar, Siddhartha P SP; Quiros, Pedro M PM; Gu, Muxin M; Jiang, Tao T; Mitchell, Jonathan J; Langdon, Ryan R; Iyer, Vivek V; Barcena, Clea C; Vijayabaskar, M S MS; Fabre, Margarete A MA; Carter, Paul P; Petrovski, Slavé S; Burgess, Stephen S; Vassiliou, George S GS
Publication Date: 2022-08

Variant appearance in text: KRAS: A146E
PubMed Link: 35835912
Variant Present in the following documents:
  • 41588_2022_1121_MOESM3_ESM.xlsx, sheet 4
View BVdb publication page



Tumor Location Is Associated With the Prevalence of Braf And Pik3ca Mutations in Patients with Wild-Type Ras Colorectal Cancer: A Prospective Multi-Center Cohort Study in Japan.

Translational Oncology
Taniguchi, Hiroya H; Uehara, Keisuke K; Nakayama, Goro G; Nakayama, Hiroshi H; Aiba, Toshisada T; Hattori, Norifumi N; Kataoka, Masato M; Nakano, Yasuyuki Y; Kawase, Yoshihisa Y; Okochi, Osamu O; Matsuoka, Hiroshi H; Utsunomiya, Setsuo S; Sakamoto, Eiji E; Mori, Yoshinori Y; Umeda, Shinichi S; Shikano, Toshio T; Komori, Koji K; Tajika, Masahiro M; Kadowaki, Shigenori S; Muro, Kei K; Yatabe, Yasushi Y
Publication Date: 2020-07

Variant appearance in text: KRAS: A146E
PubMed Link: 32428838
Variant Present in the following documents:
  • Main text
View BVdb publication page



Clinicopathological features and endoscopic characteristics of inverted sessile serrated adenomas/polyps.

Endoscopy International Open
Takashima, Kenji K; Oono, Yasuhiro Y; Kojima, Motohiro M; Ikematsu, Hiroaki H; Akimoto, Tetsuo T; Yano, Tomonori T
Publication Date: 2019-03

Variant appearance in text: KRAS: A146E
PubMed Link: 30834291
Variant Present in the following documents:
  • Main text
  • 10-1055-a-0820-2179.pdf
View BVdb publication page



Phase II trial of biweekly cetuximab and irinotecan as third-line therapy for pretreated KRAS exon 2 wild-type colorectal cancer.

Cancer Science
Osumi, Hiroki H; Shinozaki, Eiji E; Mashima, Tetsuo T; Wakatsuki, Takeru T; Suenaga, Mitsukuni M; Ichimura, Takashi T; Ogura, Mariko M; Ota, Yumiko Y; Nakayama, Izuma I; Takahari, Daisuke D; Chin, Keisho K; Miki, Yoshio Y; Yamaguchi, Kensei K
Publication Date: 2018-08

Variant appearance in text: KRAS: A146E
PubMed Link: 29908105
Variant Present in the following documents:
  • Main text
  • CAS-109-2567.pdf
View BVdb publication page



Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications
Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ
Publication Date: 2017-05-11

Variant appearance in text: KRAS: 437C>A
PubMed Link: 28492226
Variant Present in the following documents:
  • ncomms15086-s3.xlsx, sheet 1
View BVdb publication page



A retrospective observational study of clinicopathological features of KRAS, NRAS, BRAF and PIK3CA mutations in Japanese patients with metastatic colorectal cancer.

Bmc Cancer
Kawazoe, Akihito A; Shitara, Kohei K; Fukuoka, Shota S; Kuboki, Yasutoshi Y; Bando, Hideaki H; Okamoto, Wataru W; Kojima, Takashi T; Fuse, Nozomu N; Yamanaka, Takeharu T; Doi, Toshihiko T; Ohtsu, Atsushi A; Yoshino, Takayuki T
Publication Date: 2015-04-11

Variant appearance in text: KRAS: A146E
PubMed Link: 25886136
Variant Present in the following documents:
  • Main text
  • 12885_2015_Article_1276.pdf
View BVdb publication page



Simultaneous identification of 36 mutations in KRAS codons 61 and 146, BRAF, NRAS, and PIK3CA in a single reaction by multiplex assay kit.

Bmc Cancer
Bando, Hideaki H; Yoshino, Takayuki T; Shinozaki, Eiji E; Nishina, Tomohiro T; Yamazaki, Kentaro K; Yamaguchi, Kensei K; Yuki, Satoshi S; Kajiura, Shinya S; Fujii, Satoshi S; Yamanaka, Takeharu T; Tsuchihara, Katsuya K; Ohtsu, Atsushi A
Publication Date: 2013-09-03

Variant appearance in text: KRAS: A146E
PubMed Link: 24006859
Variant Present in the following documents:
  • Main text
  • 1471-2407-13-405.pdf
View BVdb publication page