Publications:

---

Characterization of clonal immunoglobulin heavy V-D-J gene rearrangements in Chinese patients with chronic lymphocytic leukemia: Clinical features and molecular profiles.

Frontiers In Oncology

Deng, Xinyue X; Zhang, Meilan M; Wang, Jiachen J; Zhou, Xiaoxi X; Xiao, Min M

Publication Date: 2023

Variant appearance in text: KRAS: A146S

PubMed Link: 36874132

Variant Present in the following documents:

• Table_1.xlsx, sheet 1

View BVdb publication page

---

High-risk multiple myeloma predicted by circulating plasma cells and its genetic characteristics.

Frontiers In Oncology

Xia, Yuan Y; Shen, Na N; Zhang, Run R; Wu, Yujie Y; Shi, Qinglin Q; Li, Jianyong J; Chen, Lijuan L; Xu, Min M; Jin, Yuanyuan Y

Publication Date: 2023

Variant appearance in text: rs121913527

PubMed Link: 36845679

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

---

Calibration of computational tools for missense variant pathogenicity classification and ClinGen recommendations for PP3/BP4 criteria.

American Journal Of Human Genetics

Pejaver, Vikas V; Byrne, Alicia B AB; Feng, Bing-Jian BJ; Pagel, Kymberleigh A KA; Mooney, Sean D SD; Karchin, Rachel R; O'Donnell-Luria, Anne A; Harrison, Steven M SM; Tavtigian, Sean V SV; Greenblatt, Marc S MS; Biesecker, Leslie G LG; Radivojac, Predrag P; Brenner, Steven E SE; ,

Publication Date: 2022-12-01

Variant appearance in text: KRAS: A146S; rs121913527

PubMed Link: 36413997

Variant Present in the following documents:

• mmc2.xlsx, sheet 1

View BVdb publication page

---

Mutational landscape of circulating tumor DNA identifies distinct molecular features associated with therapeutic response in patients with metastatic colorectal cancer.

Therapeutic Advances In Medical Oncology

Shi, Min M; Yuan, Hong H; Ji, Jun J; Zhang, Shouwei S; Li, Qingyuan Q; Chen, Yawei Y; Gong, Xiaoli X; Zhu, Zhenggang Z; Zhang, Jun J

Publication Date: 2022

Variant appearance in text: rs121913527

PubMed Link: 35096147

Variant Present in the following documents:

• sj-xls-4-tam-10.1177_17588359211070643.xls, sheet 1

View BVdb publication page

---

Single-cell analysis of gastric pre-cancerous and cancer lesions reveals cell lineage diversity and intratumoral heterogeneity.

Npj Precision Oncology

Kim, Jihyun J; Park, Charny C; Kim, Kwang H KH; Kim, Eun Hye EH; Kim, Hyunki H; Woo, Jong Kyu JK; Seong, Je Kyung JK; Nam, Ki Taek KT; Lee, Yong Chan YC; Cho, Soo Young SY

Publication Date: 2022-01-27

Variant appearance in text: rs121913527

PubMed Link: 35087207

Variant Present in the following documents:

• 41698_2022_251_MOESM1_ESM.pdf

View BVdb publication page

---

KLF3 and PAX6 are candidate driver genes in late-stage, MSI-hypermutated endometrioid endometrial carcinomas.

Plos One

Rudd, Meghan L ML; Hansen, Nancy F NF; Zhang, Xiaolu X; Urick, Mary Ellen ME; Zhang, Suiyuan S; Merino, Maria J MJ; , ; Mullikin, James C JC; Brody, Lawrence C LC; Bell, Daphne W DW

Publication Date: 2022

Variant appearance in text: rs121913527

PubMed Link: 35081118

Variant Present in the following documents:

• pone.0251286.s005.xlsx, sheet 8

View BVdb publication page

---

KLF3 and PAX6 are candidate driver genes in late-stage, MSI-hypermutated endometrioid endometrial carcinomas.

Plos One

Rudd, Meghan L ML; Hansen, Nancy F NF; Zhang, Xiaolu X; Urick, Mary Ellen ME; Zhang, Suiyuan S; Merino, Maria J MJ; , ; Mullikin, James C JC; Brody, Lawrence C LC; Bell, Daphne W DW

Publication Date: 2022

Variant appearance in text: rs121913527

PubMed Link: 35081118

Variant Present in the following documents:

• pone.0251286.s005.xlsx, sheet 8

View BVdb publication page

---

Dynamic recurrence risk and adjuvant chemotherapy benefit prediction by ctDNA in resected NSCLC.

Nature Communications

Qiu, Bin B; Guo, Wei W; Zhang, Fan F; Lv, Fang F; Ji, Ying Y; Peng, Yue Y; Chen, Xiaoxi X; Bao, Hua H; Xu, Yang Y; Shao, Yang Y; Tan, Fengwei F; Xue, Qi Q; Gao, Shugeng S; He, Jie J

Publication Date: 2021-11-19

Variant appearance in text: KRAS: 436G>T; A146S

PubMed Link: 34799585

Variant Present in the following documents:

• 41467_2021_27022_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

---

Dynamic recurrence risk and adjuvant chemotherapy benefit prediction by ctDNA in resected NSCLC.

Nature Communications

Qiu, Bin B; Guo, Wei W; Zhang, Fan F; Lv, Fang F; Ji, Ying Y; Peng, Yue Y; Chen, Xiaoxi X; Bao, Hua H; Xu, Yang Y; Shao, Yang Y; Tan, Fengwei F; Xue, Qi Q; Gao, Shugeng S; He, Jie J

Publication Date: 2021-11-19

Variant appearance in text: KRAS: 436G>T; A146S

PubMed Link: 34799585

Variant Present in the following documents:

• 41467_2021_27022_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

---

KRAS mutations are negatively correlated with immunity in colon cancer.

Aging

Fu, Xiaorui X; Wang, Xinyi X; Duanmu, Jinzhong J; Li, Taiyuan T; Jiang, Qunguang Q

Publication Date: 2020-11-26

Variant appearance in text: rs121913527

PubMed Link: 33254149

Variant Present in the following documents:

• Main text
• aging-13-202182.pdf

View BVdb publication page

---

Discovering the molecular differences between right- and left-sided colon cancer using machine learning methods.

Bmc Cancer

Jiang, Yimei Y; Yan, Xiaowei X; Liu, Kun K; Shi, Yiqing Y; Wang, Changgang C; Hu, Jiele J; Li, You Y; Wu, Qinghua Q; Xiang, Ming M; Zhao, Ren R

Publication Date: 2020-10-19

Variant appearance in text: rs121913527

PubMed Link: 33076847

Variant Present in the following documents:

• Main text
• 12885_2020_Article_7507.pdf

View BVdb publication page

---

Usefulness of a novel device to divide core needle biopsy specimens in a spatially matched fashion.

Scientific Reports

Shiraishi, Takumi T; Inui, Shogo S; Inoue, Yuta Y; Saito, Yumiko Y; Taga, Hideto H; Kaneko, Masatomo M; Tsuji, Keisuke K; Ueda, Saya S; Ueda, Takashi T; Matsugasumi, Toru T; Taniguchi, Hidefumi H; Ueno, Akihisa A; Yamada, Takeshi T; Yamada, Yasuhiro Y; Iwata, Tsuyoshi T; Fujihara, Atsuko A; Hongo, Fumiya F; Ukimura, Osamu O

Publication Date: 2020-10-13

Variant appearance in text: rs121913527

PubMed Link: 33051506

Variant Present in the following documents:

• 41598_2020_74136_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

---

Identification of pathogenic missense mutations using protein stability predictors.

Scientific Reports

Gerasimavicius, Lukas L; Liu, Xin X; Marsh, Joseph A JA

Publication Date: 2020-09-21

Variant appearance in text: KRAS: A146S

PubMed Link: 32958805

Variant Present in the following documents:

• 41598_2020_72404_MOESM2_ESM.xlsx, sheet 2

View BVdb publication page

---

Tumor Location Is Associated With the Prevalence of Braf And Pik3ca Mutations in Patients with Wild-Type Ras Colorectal Cancer: A Prospective Multi-Center Cohort Study in Japan.

Translational Oncology

Taniguchi, Hiroya H; Uehara, Keisuke K; Nakayama, Goro G; Nakayama, Hiroshi H; Aiba, Toshisada T; Hattori, Norifumi N; Kataoka, Masato M; Nakano, Yasuyuki Y; Kawase, Yoshihisa Y; Okochi, Osamu O; Matsuoka, Hiroshi H; Utsunomiya, Setsuo S; Sakamoto, Eiji E; Mori, Yoshinori Y; Umeda, Shinichi S; Shikano, Toshio T; Komori, Koji K; Tajika, Masahiro M; Kadowaki, Shigenori S; Muro, Kei K; Yatabe, Yasushi Y

Publication Date: 2020-07

Variant appearance in text: KRAS: A146S

PubMed Link: 32428838

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

---

Genetic variants and clinical significance of pediatric acute lymphoblastic leukemia.

Annals Of Translational Medicine

Zhang, Hong-Hong HH; Wang, Hong-Sheng HS; Qian, Xiao-Wen XW; Fan, Cui-Qing CQ; Li, Jun J; Miao, Hui H; Zhu, Xiao-Hua XH; Yu, Yi Y; Meng, Jian-Hua JH; Cao, Ping P; Le, Jun J; Jiang, Jun-Ye JY; Jiang, Wen-Jing WJ; Wang, Ping P; Zhai, Xiao-Wen XW

Publication Date: 2019-07

Variant appearance in text: rs121913527

PubMed Link: 31475166

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Resectable lung lesions malignancy assessment and cancer detection by ultra-deep sequencing of targeted gene mutations in plasma cell-free DNA.

Journal Of Medical Genetics

Peng, Muyun M; Xie, Yuancai Y; Li, Xiaohua X; Qian, Youhui Y; Tu, Xiaonian X; Yao, Xumei X; Cheng, Fangsheng F; Xu, Feiyue F; Kong, Deju D; He, Bing B; Liu, Chaoyu C; Cao, Fengjun F; Yang, Haoxian H; Yu, Fenglei F; Xu, Chuanbo C; Tian, Geng G

Publication Date: 2019-10

Variant appearance in text: KRAS: 436G>T; Ala146Ser

PubMed Link: 30981987

Variant Present in the following documents:

• jmedgenet-2018-105825supp002.xlsx, sheet 4

View BVdb publication page

---

Enrichment of short mutant cell-free DNA fragments enhanced detection of pancreatic cancer.

Ebiomedicine

Liu, Xiaoyu X; Liu, Lingxiao L; Ji, Yuan Y; Li, Changyu C; Wei, Tao T; Yang, Xuerong X; Zhang, Yuefang Y; Cai, Xuyu X; Gao, Yangbin Y; Xu, Weihong W; Rao, Shengxiang S; Jin, Dayong D; Lou, Wenhui W; Qiu, Zilong Z; Wang, Xiaolin X

Publication Date: 2019-03

Variant appearance in text: rs121913527

PubMed Link: 30857943

Variant Present in the following documents:

• mmc3.xlsx, sheet 2

View BVdb publication page

---

Clinicopathological features and endoscopic characteristics of inverted sessile serrated adenomas/polyps.

Endoscopy International Open

Takashima, Kenji K; Oono, Yasuhiro Y; Kojima, Motohiro M; Ikematsu, Hiroaki H; Akimoto, Tetsuo T; Yano, Tomonori T

Publication Date: 2019-03

Variant appearance in text: KRAS: A146S

PubMed Link: 30834291

Variant Present in the following documents:

• Main text

View BVdb publication page

---

ITK inhibition induced in vitro and in vivo anti-tumor activity through downregulating TCR signaling pathway in malignant T cell lymphoma.

Cancer Cell International

Liu, Yalu Y; Wang, Xiaogan X; Deng, Lijuan L; Ping, Lingyan L; Shi, Yunfei Y; Zheng, Wen W; Lin, Ningjing N; Wang, Xiaopei X; Tu, Meifeng M; Xie, Yan Y; Liu, Weiping W; Ying, Zhitao Z; Zhang, Chen C; Pan, Zhengying Z; Wang, Xi X; Ding, Ning N; Song, Yuqin Y; Zhu, Jun J

Publication Date: 2019

Variant appearance in text: KRAS: A146S

PubMed Link: 30814910

Variant Present in the following documents:

• Main text
• 12935_2019_Article_754.pdf

View BVdb publication page

---

Whole-exon sequencing of human myeloma cell lines shows mutations related to myeloma patients at relapse with major hits in the DNA regulation and repair pathways.

Journal Of Hematology & Oncology

Tessoulin, Benoît B; Moreau-Aubry, Agnès A; Descamps, Géraldine G; Gomez-Bougie, Patricia P; Maïga, Sophie S; Gaignard, Alban A; Chiron, David D; Ménoret, Emmanuelle E; Le Gouill, Steven S; Moreau, Philippe P; Amiot, Martine M; Pellat-Deceunynck, Catherine C

Publication Date: 2018-12-13

Variant appearance in text: rs121913527

PubMed Link: 30545397

Variant Present in the following documents:

• 13045_2018_679_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

---

Phase II trial of biweekly cetuximab and irinotecan as third-line therapy for pretreated KRAS exon 2 wild-type colorectal cancer.

Cancer Science

Osumi, Hiroki H; Shinozaki, Eiji E; Mashima, Tetsuo T; Wakatsuki, Takeru T; Suenaga, Mitsukuni M; Ichimura, Takashi T; Ogura, Mariko M; Ota, Yumiko Y; Nakayama, Izuma I; Takahari, Daisuke D; Chin, Keisho K; Miki, Yoshio Y; Yamaguchi, Kensei K

Publication Date: 2018-08

Variant appearance in text: KRAS: A146S

PubMed Link: 29908105

Variant Present in the following documents:

• Main text
• CAS-109-2567.pdf

View BVdb publication page

---

LitVar: a semantic search engine for linking genomic variant data in PubMed and PMC.

Nucleic Acids Research

Allot, Alexis A; Peng, Yifan Y; Wei, Chih-Hsuan CH; Lee, Kyubum K; Phan, Lon L; Lu, Zhiyong Z

Publication Date: 2018-07-02

Variant appearance in text: rs121913527

PubMed Link: 29762787

Variant Present in the following documents:

• Main text
• gky355.pdf

View BVdb publication page

---

Cis-oriented solvent-front EGFR G796S mutation in tissue and ctDNA in a patient progressing on osimertinib: a case report and review of the literature.

Lung Cancer (Auckland, N.Z.)

Klempner, Samuel J SJ; Mehta, Pareen P; Schrock, Alexa B AB; Ali, Siraj M SM; Ou, Sai-Hong Ignatius SI

Publication Date: 2017

Variant appearance in text: KRAS: A146S

PubMed Link: 29255376

Variant Present in the following documents:

• Main text
• lctt-8-241.pdf

View BVdb publication page

---

Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications

Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ

Publication Date: 2017-05-11

Variant appearance in text: N/A

PubMed Link: 28492226

Variant Present in the following documents:

View BVdb publication page

---

CHK1-targeted therapy to deplete DNA replication-stressed, p53-deficient, hyperdiploid colorectal cancer stem cells.

Gut

Manic, Gwenola G; Signore, Michele M; Sistigu, Antonella A; Russo, Giorgio G; Corradi, Francesca F; Siteni, Silvia S; Musella, Martina M; Vitale, Sara S; De Angelis, Maria Laura ML; Pallocca, Matteo M; Amoreo, Carla Azzurra CA; Sperati, Francesca F; Di Franco, Simone S; Barresi, Sabina S; Policicchio, Eleonora E; De Luca, Gabriele G; De Nicola, Francesca F; Mottolese, Marcella M; Zeuner, Ann A; Fanciulli, Maurizio M; Stassi, Giorgio G; Maugeri-Saccà, Marcello M; Baiocchi, Marta M; Tartaglia, Marco M; Vitale, Ilio I; De Maria, Ruggero R

Publication Date: 2018-05

Variant appearance in text: rs121913527

PubMed Link: 28389531

Variant Present in the following documents:

• gutjnl-2016-312623supp002.pdf

View BVdb publication page

---

Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors.

Nature Communications

Schütte, Moritz M; Risch, Thomas T; Abdavi-Azar, Nilofar N; Boehnke, Karsten K; Schumacher, Dirk D; Keil, Marlen M; Yildiriman, Reha R; Jandrasits, Christine C; Borodina, Tatiana T; Amstislavskiy, Vyacheslav V; Worth, Catherine L CL; Schweiger, Caroline C; Liebs, Sandra S; Lange, Martin M; Warnatz, Hans-Jörg HJ; Butcher, Lee M LM; Barrett, James E JE; Sultan, Marc M; Wierling, Christoph C; Golob-Schwarzl, Nicole N; Lax, Sigurd S; Uranitsch, Stefan S; Becker, Michael M; Welte, Yvonne Y; Regan, Joseph Lewis JL; Silvestrov, Maxine M; Kehler, Inge I; Fusi, Alberto A; Kessler, Thomas T; Herwig, Ralf R; Landegren, Ulf U; Wienke, Dirk D; Nilsson, Mats M; Velasco, Juan A JA; Garin-Chesa, Pilar P; Reinhard, Christoph C; Beck, Stephan S; Schäfer, Reinhold R; Regenbrecht, Christian R A CR; Henderson, David D; Lange, Bodo B; Haybaeck, Johannes J; Keilholz, Ulrich U; Hoffmann, Jens J; Lehrach, Hans H; Yaspo, Marie-Laure ML

Publication Date: 2017-02-10

Variant appearance in text: rs121913527

PubMed Link: 28186126

Variant Present in the following documents:

• ncomms14262-s5.xlsx, sheet 2

View BVdb publication page

---

A retrospective observational study of clinicopathological features of KRAS, NRAS, BRAF and PIK3CA mutations in Japanese patients with metastatic colorectal cancer.

Bmc Cancer

Kawazoe, Akihito A; Shitara, Kohei K; Fukuoka, Shota S; Kuboki, Yasutoshi Y; Bando, Hideaki H; Okamoto, Wataru W; Kojima, Takashi T; Fuse, Nozomu N; Yamanaka, Takeharu T; Doi, Toshihiko T; Ohtsu, Atsushi A; Yoshino, Takayuki T

Publication Date: 2015-04-11

Variant appearance in text: KRAS: A146S

PubMed Link: 25886136

Variant Present in the following documents:

• Main text
• 12885_2015_Article_1276.pdf

View BVdb publication page

---

NCI-60 whole exome sequencing and pharmacological CellMiner analyses.

Plos One

Reinhold, William C WC; Varma, Sudhir S; Sousa, Fabricio F; Sunshine, Margot M; Abaan, Ogan D OD; Davis, Sean R SR; Reinhold, Spencer W SW; Kohn, Kurt W KW; Morris, Joel J; Meltzer, Paul S PS; Doroshow, James H JH; Pommier, Yves Y

Publication Date: 2014

Variant appearance in text: rs121913527

PubMed Link: 25032700

Variant Present in the following documents:

• pone.0101670.s004.xlsx, sheet 1

View BVdb publication page

---

Simultaneous identification of 36 mutations in KRAS codons 61 and 146, BRAF, NRAS, and PIK3CA in a single reaction by multiplex assay kit.

Bmc Cancer

Bando, Hideaki H; Yoshino, Takayuki T; Shinozaki, Eiji E; Nishina, Tomohiro T; Yamazaki, Kentaro K; Yamaguchi, Kensei K; Yuki, Satoshi S; Kajiura, Shinya S; Fujii, Satoshi S; Yamanaka, Takeharu T; Tsuchihara, Katsuya K; Ohtsu, Atsushi A

Publication Date: 2013-09-03

Variant appearance in text: KRAS: A146S

PubMed Link: 24006859

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Use of multivariate analysis to suggest a new molecular classification of colorectal cancer.

The Journal Of Pathology

Domingo, Enric E; Ramamoorthy, Rajarajan R; Oukrif, Dahmane D; Rosmarin, Daniel D; Presz, Michal M; Wang, Haitao H; Pulker, Hannah H; Lockstone, Helen H; Hveem, Tarjei T; Cranston, Treena T; Danielsen, Havard H; Novelli, Marco M; Davidson, Brian B; Xu, Zheng-Zhou ZZ; Molloy, Peter P; Johnstone, Elaine E; Holmes, Christopher C; Midgley, Rachel R; Kerr, David D; Sieber, Oliver O; Tomlinson, Ian I

Publication Date: 2013-02

Variant appearance in text: KRAS: A146S

PubMed Link: 23165447

Variant Present in the following documents:

• path0229-0441-FigureS1.pdf

View BVdb publication page

---