KRAS c.319G>A ;(p.E107K)

Variant ID: 12-25378679-C-T

NM_004985.3(KRAS):c.319G>A;(p.E107K)

This variant was identified in 10 publications

View GRCh38 version.




Publications:


RAS Nanoclusters Selectively Sort Distinct Lipid Headgroups and Acyl Chains.

Frontiers In Molecular Biosciences
Zhou, Yong Y; Gorfe, Alemayehu A AA; Hancock, John F JF
Publication Date: 2021

Variant appearance in text: KRAS: E107K
PubMed Link: 34222339
Variant Present in the following documents:
  • Main text
  • fmolb-08-686338.pdf
View BVdb publication page



RAS Nanoclusters: Dynamic Signaling Platforms Amenable to Therapeutic Intervention.

Biomolecules
Van, Que N QN; Prakash, Priyanka P; Shrestha, Rebika R; Balius, Trent E TE; Turbyville, Thomas J TJ; Stephen, Andrew G AG
Publication Date: 2021-03-03

Variant appearance in text: KRAS: E107K
PubMed Link: 33802474
Variant Present in the following documents:
  • Main text
  • biomolecules-11-00377.pdf
View BVdb publication page



Oncogenic K-Ras4B Dimerization Enhances Downstream Mitogen-activated Protein Kinase Signaling.

Journal Of Molecular Biology
Muratcioglu, Serena S; Aydin, Cihan C; Odabasi, Ezgi E; Ozdemir, E Sila ES; Firat-Karalar, Elif Nur EN; Jang, Hyunbum H; Tsai, Chung-Jung CJ; Nussinov, Ruth R; Kavakli, Ibrahim Halil IH; Gursoy, Attila A; Keskin, Ozlem O
Publication Date: 2020-02-14

Variant appearance in text: K-Ras4B: E107K
PubMed Link: 31931009
Variant Present in the following documents:
  • Main text
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: KRAS: E107K
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 2
  • pone.0196434.s001.xlsx, sheet 3
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Spatiotemporal Analysis of K-Ras Plasma Membrane Interactions Reveals Multiple High Order Homo-oligomeric Complexes.

Journal Of The American Chemical Society
Sarkar-Banerjee, Suparna S; Sayyed-Ahmad, Abdallah A; Prakash, Priyanka P; Cho, Kwang-Jin KJ; Waxham, M Neal MN; Hancock, John F JF; Gorfe, Alemayehu A AA
Publication Date: 2017-09-27

Variant appearance in text: K-Ras4B: E107K
PubMed Link: 28863262
Variant Present in the following documents:
  • Main text
View BVdb publication page



Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications
Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ
Publication Date: 2017-05-11

Variant appearance in text: KRAS: 319G>A
PubMed Link: 28492226
Variant Present in the following documents:
  • ncomms15086-s3.xlsx, sheet 1
View BVdb publication page



Computational and biochemical characterization of two partially overlapping interfaces and multiple weak-affinity K-Ras dimers.

Scientific Reports
Prakash, Priyanka P; Sayyed-Ahmad, Abdallah A; Cho, Kwang-Jin KJ; Dolino, Drew M DM; Chen, Wei W; Li, Hongyang H; Grant, Barry J BJ; Hancock, John F JF; Gorfe, Alemayehu A AA
Publication Date: 2017-01-09

Variant appearance in text: K-Ras4B: E107K
PubMed Link: 28067274
Variant Present in the following documents:
  • Main text
  • srep40109.pdf
View BVdb publication page



Spatio-temporal mutation profiles of case-matched colorectal carcinomas and their metastases reveal unique de novo mutations in metachronous lung metastases by targeted next generation sequencing.

Molecular Cancer
Kovaleva, Valentina V; Geissler, Anna-Lena AL; Lutz, Lisa L; Fritsch, Ralph R; Makowiec, Frank F; Wiesemann, Sebastian S; Hopt, Ulrich T UT; Passlick, Bernward B; Werner, Martin M; Lassmann, Silke S
Publication Date: 2016-10-18

Variant appearance in text: KRAS: 319G>A; Glu107Lys
PubMed Link: 27756406
Variant Present in the following documents:
  • 12943_2016_549_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Preserved genetic diversity in organoids cultured from biopsies of human colorectal cancer metastases.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Weeber, Fleur F; van de Wetering, Marc M; Hoogstraat, Marlous M; Dijkstra, Krijn K KK; Krijgsman, Oscar O; Kuilman, Thomas T; Gadellaa-van Hooijdonk, Christa G M CG; van der Velden, Daphne L DL; Peeper, Daniel S DS; Cuppen, Edwin P J G EP; Vries, Robert G RG; Clevers, Hans H; Voest, Emile E EE
Publication Date: 2015-10-27

Variant appearance in text: KRAS: E107K
PubMed Link: 26460009
Variant Present in the following documents:
  • Main text
View BVdb publication page